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List of works by Thomas Thum

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MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

scientific journal article
MicroRNAs in the human heart: a clue to fetal gene reprogramming in heart failure

scientific article (publication date: 17 July 2007)
Cardiac fibroblast-derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy

scientific article
The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy.

scientific article published on January 2012
Circulating long noncoding RNA, LIPCAR, predicts survival in patients with heart failure

scientific article published on 24 March 2014
LDL cholesterol upregulates synthesis of asymmetrical dimethylarginine in human endothelial cells: involvement of S-adenosylmethionine-dependent methyltransferases

scientific article (publication date: 21 July 2000)
MicroRNA-24 regulates vascularity after myocardial infarction

scientific article published on 25 July 2011
Regulation and function of miRNA-21 in health and disease.

scientific article published on 07 July 2011
Effect of intravenous iron sucrose on exercise tolerance in anemic and nonanemic patients with symptomatic chronic heart failure and iron deficiency FERRIC-HF: a randomized, controlled, observer-blinded trial

scientific article
Endothelial nitric oxide synthase uncoupling impairs endothelial progenitor cell mobilization and function in diabetes

scientific article published on 01 March 2007
Diagnostic and prognostic impact of six circulating microRNAs in acute coronary syndrome

scientific article
Exosomes: new players in cell-cell communication.

scientific article published on 10 August 2012
Transforming growth factor-β-induced endothelial-to-mesenchymal transition is partly mediated by microRNA-21.

scientific article published on 17 November 2011
Circulating microRNAs as biomarkers and potential paracrine mediators of cardiovascular disease

scientific article published on 01 October 2010
MicroRNAs as mediators and therapeutic targets in chronic kidney disease

scientific article published on March 22, 2011
Age-dependent impairment of endothelial progenitor cells is corrected by growth-hormone-mediated increase of insulin-like growth-factor-1.

scientific article published on 18 January 2007
Non-coding RNAs in cardiac remodeling and heart failure.

scientific article published on August 2013
MiR-378 controls cardiac hypertrophy by combined repression of mitogen-activated protein kinase pathway factors

scientific article
Circulating miR-210 predicts survival in critically ill patients with acute kidney injury

scientific article
Role of miR-21 in the pathogenesis of atrial fibrosis

scientific article
Macrophage microRNA-155 promotes cardiac hypertrophy and failure.

scientific article published on 16 August 2013
Urinary miR-210 as a mediator of acute T-cell mediated rejection in renal allograft recipients

scientific article published on 3 August 2011
Effects of physical exercise on myocardial telomere-regulating proteins, survival pathways, and apoptosis

scientific article
miR-212 and miR-132 are required for epithelial stromal interactions necessary for mouse mammary gland development.

scientific article published on 7 November 2010
Circulating microRNAs as potential biomarkers of aerobic exercise capacity

scientific article published on 20 December 2013
Short communication: asymmetric dimethylarginine impairs angiogenic progenitor cell function in patients with coronary artery disease through a microRNA-21-dependent mechanism

scientific journal article
MicroRNA therapeutics in cardiovascular medicine

scientific article published on December 13, 2011
Circulating endothelial progenitor cells in patients with Eisenmenger syndrome and idiopathic pulmonary arterial hypertension.

scientific article published on 2 June 2008
Biogenesis and regulation of cardiovascular microRNAs.

scientific article published on July 2011
Hallmarks of ion channel gene expression in end-stage heart failure

scientific article
Gene expression in distinct regions of the heart

scientific article (publication date: 18 March 2000)
Suppression of endothelial progenitor cells in human coronary artery disease by the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine

scientific article published on 10 October 2005
A phenotypic screen to identify hypertrophy-modulating microRNAs in primary cardiomyocytes

scientific article
Mechanisms underlying recoupling of eNOS by HMG-CoA reductase inhibition in a rat model of streptozotocin-induced diabetes mellitus.

scientific article
Resveratrol reverses endothelial nitric-oxide synthase uncoupling in apolipoprotein E knockout mice.

scientific article published on 7 July 2010
SERCA2a gene therapy restores microRNA-1 expression in heart failure via an Akt/FoxO3A-dependent pathway

scientific journal article
Regulated microRNAs in the CSF of patients with multiple sclerosis: a case-control study

scientific article published on 17 October 2012
Signal transducer and activator of transcription 3-mediated regulation of miR-199a-5p links cardiomyocyte and endothelial cell function in the heart: a key role for ubiquitin-conjugating enzymes

scientific article published on 21 October 2010
Comparison of different miR-21 inhibitor chemistries in a cardiac disease model

scientific article published on February 2011
Prevention of liver cancer cachexia-induced cardiac wasting and heart failure

scientific article published on 29 August 2013
MicroRNAs in hypertension: mechanisms and therapeutic targets.

scientific article published on February 2012
A signature of circulating microRNAs differentiates takotsubo cardiomyopathy from acute myocardial infarction

scientific article published on 17 September 2013
Nfat and miR-25 cooperate to reactivate the transcription factor Hand2 in heart failure

scientific journal article
miRNA screening reveals a new miRNA family stimulating iPS cell generation via regulation of Meox2.

scientific article
MicroRNA-22 increases senescence and activates cardiac fibroblasts in the aging heart

scientific article published on April 27, 2012
MicroRNA-24 antagonism prevents renal ischemia reperfusion injury

scientific article
Testosterone, cytochrome P450, and cardiac hypertrophy

scientific article published in October 2002
Epigenetic modifications in cardiovascular disease.

scientific article published on 11 January 2012
MicroRNAs in myocardial infarction.

scientific article published on February 2013
Targeting myocardial remodelling to develop novel therapies for heart failure: a position paper from the Working Group on Myocardial Function of the European Society of Cardiology

scientific article

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