List of works - Ian E. Gentle

A non-death function of the mitochondrial apoptosis apparatus in immunity

scientific article published on 12 April 2019

Cell wall integrity is linked to mitochondria and phospholipid homeostasis in Candida albicans through the activity of the post-transcriptional regulator Ccr4-Pop2.

scientific article

Conserved motifs reveal details of ancestry and structure in the small TIM chaperones of the mitochondrial intermembrane space.

scientific article

Conserved substrate binding by chaperones in the bacterial periplasm and the mitochondrial intermembrane space

scientific article

Direct production of proteins with N-terminal cysteine for site-specific conjugation

scientific article

Diversity of cell death signaling pathways in macrophages upon infection with modified vaccinia virus Ankara (MVA)

scientific article published on 28 October 2021

In TNF-stimulated cells, RIPK1 promotes cell survival by stabilizing TRAF2 and cIAP1, which limits induction of non-canonical NF-kappaB and activation of caspase-8

scientific article

Inhibitor of apoptosis proteins are required for effective fusion of autophagosomes with lysosomes.

scientific article published on 9 May 2018

Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation.

scientific article published in February 2012

Inhibitors of apoptosis proteins (IAPs) are required for effective T-cell expansion/survival during antiviral immunity in mice

scientific article published on 12 December 2013

Integral membrane proteins in the mitochondrial outer membrane of Saccharomyces cerevisiae

scientific article

Mature DIABLO/Smac is produced by the IMP protease complex on the mitochondrial inner membrane

scientific article

Molecular architecture and function of the Omp85 family of proteins

scientific article

New Perspectives in TNF-R1-Induced NF-κB Signaling

scientific article published on 01 January 2011

RIPK1 is not essential for TNFR1-induced activation of NF-kappaB.

scientific article published on 20 November 2009

Survival and differentiation defects contribute to neutropenia in glucose-6-phosphatase-β (G6PC3) deficiency in a model of mouse neutrophil granulocyte differentiation.

scientific article published on 17 May 2013

TAK1 is required for survival of mouse fibroblasts treated with TRAIL, and does so by NF-kappaB dependent induction of cFLIPL.

scientific article

TIR-domain-containing adapter-inducing interferon-β (TRIF) forms filamentous structures, whose pro-apoptotic signalling is terminated by autophagy

scientific article published on 28 April 2017

TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor (tnf) to efficiently activate nf-{kappa}b and to prevent tnf-induced apoptosis.

scientific article published on December 2009

The AML-associated K313 mutation enhances C/EBPα activity by leading to C/EBPα overexpression

scientific article published on 05 July 2021

The Omp85 family of proteins is essential for outer membrane biogenesis in mitochondria and bacteria.

scientific article

List of works by Ian E. Gentle

A non-death function of the mitochondrial apoptosis apparatus in immunity

Cell wall integrity is linked to mitochondria and phospholipid homeostasis in Candida albicans through the activity of the post-transcriptional regulator Ccr4-Pop2.

Conserved motifs reveal details of ancestry and structure in the small TIM chaperones of the mitochondrial intermembrane space.

Conserved substrate binding by chaperones in the bacterial periplasm and the mitochondrial intermembrane space

Direct production of proteins with N-terminal cysteine for site-specific conjugation

Diversity of cell death signaling pathways in macrophages upon infection with modified vaccinia virus Ankara (MVA)

In TNF-stimulated cells, RIPK1 promotes cell survival by stabilizing TRAF2 and cIAP1, which limits induction of non-canonical NF-kappaB and activation of caspase-8

Inhibitor of apoptosis proteins are required for effective fusion of autophagosomes with lysosomes.

Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation.

Inhibitors of apoptosis proteins (IAPs) are required for effective T-cell expansion/survival during antiviral immunity in mice

Integral membrane proteins in the mitochondrial outer membrane of Saccharomyces cerevisiae

Mature DIABLO/Smac is produced by the IMP protease complex on the mitochondrial inner membrane

Molecular architecture and function of the Omp85 family of proteins

New Perspectives in TNF-R1-Induced NF-κB Signaling

RIPK1 is not essential for TNFR1-induced activation of NF-kappaB.

Survival and differentiation defects contribute to neutropenia in glucose-6-phosphatase-β (G6PC3) deficiency in a model of mouse neutrophil granulocyte differentiation.

TAK1 is required for survival of mouse fibroblasts treated with TRAIL, and does so by NF-kappaB dependent induction of cFLIPL.

TIR-domain-containing adapter-inducing interferon-β (TRIF) forms filamentous structures, whose pro-apoptotic signalling is terminated by autophagy

TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor (tnf) to efficiently activate nf-{kappa}b and to prevent tnf-induced apoptosis.

The AML-associated K313 mutation enhances C/EBPα activity by leading to C/EBPα overexpression

The Omp85 family of proteins is essential for outer membrane biogenesis in mitochondria and bacteria.