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List of works by Yue Lu

A CpG island methylator phenotype in acute myeloid leukemia independent of IDH mutations and associated with a favorable outcome.

scientific article published on 11 January 2017

A Molecular Portrait of High-Grade Ductal Carcinoma In Situ

scientific article published on 6 August 2015

A polynomial time solvable formulation of multiple sequence alignment

scientific article

ATXN7L3 and ENY2 Coordinate Activity of Multiple H2B Deubiquitinases Important for Cellular Proliferation and Tumor Growth.

scientific article published on 27 April 2016

Access to the nucleus and functional association with c-Myc is required for the full oncogenic potential of ΔEGFR/EGFRvIII

scientific article published on 17 December 2012

Activation of HERV-K Env protein is essential for tumorigenesis and metastasis of breast cancer cells

scientific article published on 20 August 2016

Age-related epigenetic drift in the pathogenesis of MDS and AML.

scientific article published on 10 January 2014

Analysis of DNA polymerase ν function in meiotic recombination, immunoglobulin class-switching, and DNA damage tolerance.

scientific article

Analysis of epigenetic modifications by next generation sequencing

scientific article

Architecture of epigenetic reprogramming following Twist1-mediated epithelial-mesenchymal transition

scientific article

Arginine methylation facilitates the recruitment of TOP3B to chromatin to prevent R loop accumulation.

scientific article

CARM1 methylates MED12 to regulate its RNA-binding ability

scientific article published on 19 September 2018

Caloric restriction delays age-related methylation drift

scientific article published on 14 September 2017

Combinations of Tyrosine Kinase Inhibitor and ERAD Inhibitor Promote Oxidative Stress-Induced Apoptosis through ATF4 and KLF9 in Medullary Thyroid Cancer

scientific article published on 14 December 2018

Comprehensive analysis of gene expression patterns in Friedreich's ataxia fibroblasts by RNA sequencing reveals altered levels of protein synthesis factors and solute carriers.

scientific article published in November 2017

Conserved DNA methylation patterns in healthy blood cells and extensive changes in leukemia measured by a new quantitative technique ⬇️

scientific article published on October 17, 2012

Correction: SOX9 Regulates Multiple Genes in Chondrocytes, Including Genes Encoding ECM Proteins, ECM Modification Enzymes, Receptors, and Transporters.

scientific article published on 12 November 2015

Corrigendum: LSD1 is essential for oocyte meiotic progression by regulating CDC25B expression in mice

scientific article published on 20 April 2016

DMBA induced mouse mammary tumors display high incidence of activating Pik3caH1047 and loss of function Pten mutations

scientific article published on 31 August 2016

DNA Methylation Signature Reveals Cell Ontogeny of Renal Cell Carcinomas.

scientific article published on 02 June 2016

DNMT3L facilitates DNA methylation partly by maintaining DNMT3A stability in mouse embryonic stem cells

article

Defects of Lipid Synthesis Are Linked to the Age-Dependent Demyelination Caused by Lamin B1 Overexpression

scientific article

Deficient LRRC8A-dependent volume-regulated anion channel activity is associated with male infertility in mice

article

Defining a Population of Stem-like Human Prostate Cancer Cells That Can Generate and Propagate Castration-Resistant Prostate Cancer.

scientific article published on 8 April 2016

Developing a Novel Two-Dimensional Culture System to Enrich Human Prostate Luminal Progenitors that Can Function as a Cell of Origin for Prostate Cancer

scientific article published on 29 September 2016

Digital Restriction Enzyme Analysis of Methylation (DREAM).

scientific article

Dnmt3a is essential for hematopoietic stem cell differentiation

scientific article

Down-regulation of human endogenous retrovirus type K (HERV-K) viral env RNA in pancreatic cancer cells decreases cell proliferation and tumor growth.

scientific article

Epigenetic synergy between decitabine and platinum derivatives

scientific article

Expanded GAA repeats impede transcription elongation through the FXN gene and induce transcriptional silencing that is restricted to the FXN locus

scientific article

GCN5 Regulates FGF Signaling and Activates Selective MYC Target Genes during Early Embryoid Body Differentiation

scientific article published on 12 December 2017

Gcn5 and PCAF negatively regulate interferon-β production through HAT-independent inhibition of TBK1.

scientific article

Genetic deletion or small-molecule inhibition of the arginine methyltransferase PRMT5 exhibit anti-tumoral activity in mouse models of MLL-rearranged AML.

scientific article published on 30 June 2017

Histone 2B-GFP Label-Retaining Prostate Luminal Cells Possess Progenitor Cell Properties and Are Intrinsically Resistant to Castration.

scientific article published on 19 December 2017

Histone H3K4 methylation regulates deactivation of the spindle assembly checkpoint through direct binding of Mad2

scientific article published on 19 May 2016

Histone methylation regulator PTIP is required to maintain normal and leukemic bone marrow niches

article published in the Proceedings of the National Academy of Sciences of the United States of America

Identification of the NF-κB activating protein-like locus as a risk locus for rheumatoid arthritis.

scientific article published on 06 December 2012

Improving accuracy of multiple sequence alignment algorithms based on alignment of neighboring residues

scientific article published on 04 December 2008

Integrated genetic approaches identify the molecular mechanisms of Sox4 in early B-cell development: intricate roles for RAG1/2 and CK1ε.

scientific article

KDM6B overexpression activates innate immune signaling and impairs hematopoiesis in mice

scientific article published on 01 October 2018

LRIG1 is a pleiotropic androgen receptor-regulated feedback tumor suppressor in prostate cancer

scientific article published on 02 December 2019

LSD1 is essential for oocyte meiotic progression by regulating CDC25B expression in mice

scientific article

Linking prostate cancer cell AR heterogeneity to distinct castration and enzalutamide responses

scientific article published in Nature Communications

Maternal Setdb1 Is Required for Meiotic Progression and Preimplantation Development in Mouse

scientific article

Methylome sequencing for fibrolamellar hepatocellular carcinoma depicts distinctive features

scientific article

MicroRNA-141 suppresses prostate cancer stem cells and metastasis by targeting a cohort of pro-metastasis genes

scientific article published on 23 January 2017

Molecular mechanism by which the nucleoid occlusion factor, SlmA, keeps cytokinesis in check

scientific article

Mouse models of overexpression reveal distinct oncogenic roles for different type I protein arginine methyltransferases

article

Multiple sequence alignment based on profile alignment of intermediate sequences

scientific article published in September 2008

NANOG reprograms prostate cancer cells to castration resistance via dynamically repressing and engaging the AR/FOXA1 signaling axis.

scientific article published on 15 November 2016

Oncogenic and osteolytic functions of histone demethylase NO66 in castration-resistant prostate cancer

scientific article published on 11 March 2019

PHF20 Readers Link Methylation of Histone H3K4 and p53 with H4K16 Acetylation.

scientific article published on October 2016

RNA sequencing analyses reveal novel differentially expressed genes and pathways in pancreatic cancer

scientific article published on 22 March 2017

SOX9 regulates multiple genes in chondrocytes, including genes encoding ECM proteins, ECM modification enzymes, receptors, and transporters

scientific article

Serum exosomal miR-4772-3p is a predictor of tumor recurrence in stage II and III colon cancer

scientific article published on 24 October 2016

Stabilization of the promoter nucleosomes in nucleosome-free regions by the yeast Cyc8-Tup1 corepressor.

scientific article published on 2 November 2012

Stem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer

scientific article published on 29 February 2016

Structural basis of specific DNA binding by the transcription factor ZBTB24

scientific article published on 01 September 2019

Systematic evaluation of RNA-Seq preparation protocol performance

scientific article published on 11 July 2019

TDRD3 is an effector molecule for arginine-methylated histone marks

scientific article

TET1 is a maintenance DNA demethylase that prevents methylation spreading in differentiated cells.

scientific article

TET2 Mutations Affect Non-CpG Island DNA Methylation at Enhancers and Transcription Factor-Binding Sites in Chronic Myelomonocytic Leukemia.

scientific article published on 13 May 2015

The arginine methyltransferase CARM1 represses p300•ACT•CREMτ activity and is required for spermiogenesis.

scientific article

The epigenome of AML stem and progenitor cells ⬇️

scientific article published on December 18, 2012

The tumor promoting activity of the EP4 receptor for prostaglandin E2 in murine skin.

scientific article

Transcriptional consequences of XPA disruption in human cell lines.

scientific article

USP22 controls multiple signaling pathways that are essential for vasculature formation in the mouse placenta

scientific article published on 22 February 2019

dsPIG: a tool to predict imprinted genes from the deep sequencing of whole transcriptomes ⬇️

scientific article published on October 19, 2012

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