Search filters

List of works by Nico Lachmann

A ubiquitous chromatin opening element prevents transgene silencing in pluripotent stem cells and their differentiated progeny

scientific article published on 01 March 2013

Bioreactor-based mass production of human iPSC-derived macrophages enables immunotherapies against bacterial airway infections

scientific article published in Nature Communications

Clonal inventory screens uncover monoclonality following serial transplantation of MGMT P140K-transduced stem cells and dose-intense chemotherapy

scientific article published on 11 April 2011

Concise Review: Towards the Clinical Translation of Induced Pluripotent Stem Cell-Derived Blood Cells-Ready for Take-Off

scientific article published on 26 December 2018

Deoxycytidine-kinase knockdown as a novel myeloprotective strategy in the context of fludarabine, cytarabine or cladribine therapy.

scientific article published on 29 April 2015

Efficient hematopoietic redifferentiation of induced pluripotent stem cells derived from primitive murine bone marrow cells

scientific article published on 24 August 2011

Efficient in vivo regulation of cytidine deaminase expression in the haematopoietic system using a doxycycline-inducible lentiviral vector system.

scientific article published on 17 May 2012

Ex vivo Generation of Genetically Modified Macrophages from Human Induced Pluripotent Stem Cells.

scientific article published on 16 May 2017

Gene correction of human induced pluripotent stem cells repairs the cellular phenotype in pulmonary alveolar proteinosis.

scientific article published in January 2014

Generation of HLA-universal iPSCs-derived megakaryocytes and platelets for survival under refractoriness conditions

scientific article

Hematopoietic stem cell gene therapy for IFNγR1 deficiency protects mice from mycobacterial infections

scientific article published on 12 December 2017

Human Lentiviral Gene Therapy Restores the Cellular Phenotype of Autosomal Recessive Complete IFN-γR1 Deficiency

scientific article published on 11 April 2020

Impaired IFNγ-Signaling and Mycobacterial Clearance in IFNγR1-Deficient Human iPSC-Derived Macrophages

scientific article

In vivo enrichment of cytidine deaminase gene-modified hematopoietic cells by prolonged cytosine-arabinoside application

scientific article published on 16 January 2012

Large-scale hematopoietic differentiation of human induced pluripotent stem cells provides granulocytes or macrophages for cell replacement therapies

scientific article published on February 2015

Lentiviral MGMT(P140K)-mediated in vivo selection employing a ubiquitous chromatin opening element (A2UCOE) linked to a cellular promoter.

scientific article published on 27 May 2014

Lost in translation: pluripotent stem cell-derived hematopoiesis

scientific article (publication date: November 2015)

Lung surfactant metabolism: early in life, early in disease and target in cell therapy.

scientific article

MicroRNA-150-regulated vectors allow lymphocyte-sparing transgene expression in hematopoietic gene therapy

scientific article published on 6 October 2011

MicroRNA-Based Therapy of GATA2-Deficient Vascular Disease.

scientific article published on 25 October 2016

Monocyte/macrophage lineage commitment and distribution are affected by the lack of regulatory T cells in scurfy mice.

scientific article

Myeloprotection by cytidine deaminase gene transfer in antileukemic therapy.

scientific article published on March 2013

Patient iPSC-Derived Macrophages to Study Inborn Errors of the IFN-γ Responsive Pathway

scientific article published on 19 February 2020

Promoter and lineage independent anti-silencing activity of the A2 ubiquitous chromatin opening element for optimized human pluripotent stem cell-based gene therapy.

scientific article published on 26 November 2013

Pulmonary Transplantation of Human iPSC-derived Macrophages Ameliorates Pulmonary Alveolar Proteinosis.

scientific article published on 13 April 2018

Pulmonary macrophage transplantation therapy

scientific article

Pulmonary transplantation of macrophage progenitors as effective and long-lasting therapy for hereditary pulmonary alveolar proteinosis

scientific article published in August 2014

TALEN-mediated functional correction of X-linked chronic granulomatous disease in patient-derived induced pluripotent stem cells

scientific article published on 3 August 2015

TALEN-mediated functional correction of human iPSC-derived macrophages in context of hereditary pulmonary alveolar proteinosis.

scientific article published on 9 November 2017

Targeted Integration of Inducible Caspase-9 in Human iPSCs Allows Efficient in vitro Clearance of iPSCs and iPSC-Macrophages

scientific article published on 03 April 2020

Tightly regulated 'all-in-one' lentiviral vectors for protection of human hematopoietic cells from anticancer chemotherapy.

scientific article

iPSC-Derived Macrophages Effectively Treat Pulmonary Alveolar Proteinosis in Csf2rb-Deficient Mice

scientific article published on 09 August 2018

Paulina is supported by:

About Paulina

Help