List of works - Christopher E Andoniou

"Natural Regulators": NK Cells as Modulators of T Cell Immunity

scientific article

A chemokine-like viral protein enhances alpha interferon production by plasmacytoid dendritic cells but delays CD8+ T cell activation and impairs viral clearance.

scientific article published on 08 May 2013

A natural genetic variant of granzyme B confers lethality to a common viral infection

scientific article (publication date: December 2014)

A novel checkpoint in the Bcl-2-regulated apoptotic pathway revealed by murine cytomegalovirus infection of dendritic cells

scientific article

ASC modulates CTL cytotoxicity and transplant outcome independent of the inflammasome

scientific article published on 22 May 2020

Acute GVHD results in a severe DC defect that prevents T-cell priming and leads to fulminant cytomegalovirus disease in mice

scientific article

Association of p59(fyn) with the T lymphocyte costimulatory receptor CD2. Binding of the Fyn Src homology (SH) 3 domain is regulated by the Fyn SH2 domain.

scientific article

CD83 increases MHC II and CD86 on dendritic cells by opposing IL-10-driven MARCH1-mediated ubiquitination and degradation. ⬇️

scientific article

CIS is a potent checkpoint in NK cell-mediated tumor immunity

scientific article

Cathepsin C limits acute viral infection independently of NK cell and CD8+ T-cell cytolytic function.

scientific article published on 26 October 2010

Cbl-mediated negative regulation of the Syk tyrosine kinase. A critical role for Cbl phosphotyrosine-binding domain binding to Syk phosphotyrosine 323

scientific article

CpG pretreatment enhances antiviral T-cell immunity against cytomegalovirus

scientific article published on 14 May 2013

Cross-talk between dendritic cells and natural killer cells in viral infection

scientific article

Cytomegalovirus establishes a latent reservoir and triggers long-lasting inflammation in the eye.

scientific article published on 31 May 2018

Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice

scientific article published on 26 June 2015

Die Another Day: Inhibition of Cell Death Pathways by Cytomegalovirus.

scientific article published on 2 September 2017

Infection of dendritic cells by murine cytomegalovirus induces functional paralysis

scientific article published on 01 November 2001

Innate immunity defines the capacity of antiviral T cells to limit persistent infection

scientific article

Interaction between conventional dendritic cells and natural killer cells is integral to the activation of effective antiviral immunity.

scientific article

Killers and beyond: NK-cell-mediated control of immune responses.

scientific article

Loss of c-Cbl RING finger function results in high-intensity TCR signaling and thymic deletion.

scientific article

MCMV-mediated inhibition of the pro-apoptotic Bak protein is required for optimal in vivo replication

scientific article

Murine cytomegalovirus infection exacerbates complex IV deficiency in a model of mitochondrial disease

scientific article published on 04 March 2020

NK cells require IL-28R for optimal in vivo activity

scientific article published on 21 April 2015

Natural killer cells in viral infection: more than just killers.

scientific article published on December 2006

Ocular antigen does not cause disease unless presented in the context of inflammation.

scientific article published on 27 October 2017

Peripheral natural killer cell maturation depends on the transcription factor Aiolos

scientific article

Strain-specific antibody therapy prevents cytomegalovirus reactivation after transplantation

scientific article

Suicide watch: how cytomegalovirus interferes with the cell-death pathways of infected cells.

scientific article published on 14 April 2010

TRAIL+ NK cells control CD4+ T cell responses during chronic viral infection to limit autoimmunity.

scientific article published on October 2014

The Avidity Game: Selecting Natural-Born Killers

scientific article published on 01 June 2019

The Cbl protooncogene product: from an enigmatic oncogene to center stage of signal transduction.

scientific article published on January 1997

The Murine Natural Cytotoxic Receptor NKp46/NCR1 Controls TRAIL Protein Expression in NK Cells and ILC1s.

scientific article published in March 2018

The RING Finger Domain of Cbl Is Essential for Negative Regulation of the Syk Tyrosine Kinase

scientific article published in Journal of Biological Chemistry

The early kinetics of cytomegalovirus-specific CD8+ T-cell responses are not affected by antigen load or the absence of perforin or gamma interferon

scientific article published on 12 March 2008

The early monocytic response to cytomegalovirus infection is MyD88 dependent but occurs independently of common inflammatory cytokine signals

scientific article published on 16 December 2013

The roles of interferon-γ and perforin in antiviral immunity in mice that differ in genetically determined NK-cell-mediated antiviral activity

scientific article published on 30 June 2009

The two major sites of cbl tyrosine phosphorylation in abl-transformed cells select the crkL SH2 domain

scientific journal article

Virally mediated inhibition of Bax in leukocytes promotes dissemination of murine cytomegalovirus

scientific article published on 24 October 2008

List of works by Christopher E Andoniou

"Natural Regulators": NK Cells as Modulators of T Cell Immunity

A chemokine-like viral protein enhances alpha interferon production by plasmacytoid dendritic cells but delays CD8+ T cell activation and impairs viral clearance.

A natural genetic variant of granzyme B confers lethality to a common viral infection

A novel checkpoint in the Bcl-2-regulated apoptotic pathway revealed by murine cytomegalovirus infection of dendritic cells

ASC modulates CTL cytotoxicity and transplant outcome independent of the inflammasome

Acute GVHD results in a severe DC defect that prevents T-cell priming and leads to fulminant cytomegalovirus disease in mice

Association of p59(fyn) with the T lymphocyte costimulatory receptor CD2. Binding of the Fyn Src homology (SH) 3 domain is regulated by the Fyn SH2 domain.

CD83 increases MHC II and CD86 on dendritic cells by opposing IL-10-driven MARCH1-mediated ubiquitination and degradation. ⬇️

CIS is a potent checkpoint in NK cell-mediated tumor immunity

Cathepsin C limits acute viral infection independently of NK cell and CD8+ T-cell cytolytic function.

Cbl-mediated negative regulation of the Syk tyrosine kinase. A critical role for Cbl phosphotyrosine-binding domain binding to Syk phosphotyrosine 323

CpG pretreatment enhances antiviral T-cell immunity against cytomegalovirus

Cross-talk between dendritic cells and natural killer cells in viral infection

Cytomegalovirus establishes a latent reservoir and triggers long-lasting inflammation in the eye.

Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice

Die Another Day: Inhibition of Cell Death Pathways by Cytomegalovirus.

Infection of dendritic cells by murine cytomegalovirus induces functional paralysis

Innate immunity defines the capacity of antiviral T cells to limit persistent infection

Interaction between conventional dendritic cells and natural killer cells is integral to the activation of effective antiviral immunity.

Killers and beyond: NK-cell-mediated control of immune responses.

Loss of c-Cbl RING finger function results in high-intensity TCR signaling and thymic deletion.

MCMV-mediated inhibition of the pro-apoptotic Bak protein is required for optimal in vivo replication

Murine cytomegalovirus infection exacerbates complex IV deficiency in a model of mitochondrial disease

NK cells require IL-28R for optimal in vivo activity

Natural killer cells in viral infection: more than just killers.

Ocular antigen does not cause disease unless presented in the context of inflammation.

Peripheral natural killer cell maturation depends on the transcription factor Aiolos

Strain-specific antibody therapy prevents cytomegalovirus reactivation after transplantation

Suicide watch: how cytomegalovirus interferes with the cell-death pathways of infected cells.

TRAIL+ NK cells control CD4+ T cell responses during chronic viral infection to limit autoimmunity.

The Avidity Game: Selecting Natural-Born Killers

The Cbl protooncogene product: from an enigmatic oncogene to center stage of signal transduction.

The Murine Natural Cytotoxic Receptor NKp46/NCR1 Controls TRAIL Protein Expression in NK Cells and ILC1s.

The RING Finger Domain of Cbl Is Essential for Negative Regulation of the Syk Tyrosine Kinase

The early kinetics of cytomegalovirus-specific CD8+ T-cell responses are not affected by antigen load or the absence of perforin or gamma interferon

The early monocytic response to cytomegalovirus infection is MyD88 dependent but occurs independently of common inflammatory cytokine signals

The roles of interferon-γ and perforin in antiviral immunity in mice that differ in genetically determined NK-cell-mediated antiviral activity

The two major sites of cbl tyrosine phosphorylation in abl-transformed cells select the crkL SH2 domain

Virally mediated inhibition of Bax in leukocytes promotes dissemination of murine cytomegalovirus