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List of works by Niels A. Lemmermann

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Murine model of cytomegalovirus latency and reactivation.

scientific article published on January 2008
Mast cells expedite control of pulmonary murine cytomegalovirus infection by enhancing the recruitment of protective CD8 T cells to the lungs

scientific article
The immune evasion paradox: immunoevasins of murine cytomegalovirus enhance priming of CD8 T cells by preventing negative feedback regulation.

scientific article published on 24 September 2008
Non-redundant and redundant roles of cytomegalovirus gH/gL complexes in host organ entry and intra-tissue spread.

scientific article published on 6 February 2015
In vivo impact of cytomegalovirus evasion of CD8 T-cell immunity: facts and thoughts based on murine models.

scientific article published on 08 October 2010
Epitope-specific in vivo protection against cytomegalovirus disease by CD8 T cells in the murine model of preemptive immunotherapy

scientific article
Superresolution imaging of biological nanostructures by spectral precision distance microscopy.

scientific article published on September 2011
Peptide Processing Is Critical for T-Cell Memory Inflation and May Be Optimized to Improve Immune Protection by CMV-Based Vaccine Vectors

scientific article
Single cell detection of latent cytomegalovirus reactivation in host tissue.

scientific article published on 16 February 2011
A novel transmembrane domain mediating retention of a highly motile herpesvirus glycoprotein in the endoplasmic reticulum

scientific article
Polyclonal cytomegalovirus-specific antibodies not only prevent virus dissemination from the portal of entry but also inhibit focal virus spread within target tissues

scientific article published on 26 March 2008
NKG2D induces Mcl-1 expression and mediates survival of CD8 memory T cell precursors via phosphatidylinositol 3-kinase

scientific article published on 26 June 2013
Evaluating Human T-Cell Therapy of Cytomegalovirus Organ Disease in HLA-Transgenic Mice

scientific article published on 16 July 2015
Superior induction and maintenance of protective CD8 T cells in mice infected with mouse cytomegalovirus vector expressing RAE-1γ.

scientific article published on 19 September 2013
Antigen presentation under the influence of 'immune evasion' proteins and its modulation by interferon-gamma: implications for immunotherapy of cytomegalovirus infection with antiviral CD8 T cells

scientific article published on 09 September 2012
Mast cells as rapid innate sensors of cytomegalovirus by TLR3/TRIF signaling-dependent and -independent mechanisms

scientific article
Mouse Model of Cytomegalovirus Disease and Immunotherapy in the Immunocompromised Host: Predictions for Medical Translation that Survived the "Test of Time"

scientific article published on 06 December 2018
Murine cytomegalovirus (CMV) infection via the intranasal route offers a robust model of immunity upon mucosal CMV infection.

scientific article
Immune control in the absence of immunodominant epitopes: implications for immunotherapy of cytomegalovirus infection with antiviral CD8 T cells

scientific article published on 14 September 2012
Mast cells: innate attractors recruiting protective CD8 T cells to sites of cytomegalovirus infection.

scientific article
Spatial distribution and structural arrangement of a murine cytomegalovirus glycoprotein detected by SPDM localization microscopy.

scientific article published on 7 February 2014
Refining human T-cell immunotherapy of cytomegalovirus disease: a mouse model with 'humanized' antigen presentation as a new preclinical study tool

scientific article
Reconstitution of CD8 T Cells Protective against Cytomegalovirus in a Mouse Model of Hematopoietic Cell Transplantation: Dynamics and Inessentiality of Epitope Immunodominance.

scientific article published on 14 June 2016
Cytomegalovirus vector expressing RAE-1γ induces enhanced anti-tumor capacity of murine CD8+ T cells.

scientific article published on 14 June 2017
Enhancerless cytomegalovirus is capable of establishing a low-level maintenance infection in severely immunodeficient host tissues but fails in exponential growth.

scientific article
Cellular reservoirs of latent cytomegaloviruses

scientific article published on 22 April 2019
Recent advances in CMV tropism, latency, and diagnosis during aging.

scientific article
The murine cytomegalovirus M35 protein antagonizes type I IFN induction downstream of pattern recognition receptors by targeting NF-κB mediated transcription

scientific article (publication date: May 2017)
NKG2D stimulation of CD8+ T cells during priming promotes their capacity to produce cytokines in response to viral infection in mice.

scientific article published on 4 April 2017
Principles for studying in vivo attenuation of virus mutants: defining the role of the cytomegalovirus gH/gL/gO complex as a paradigm.

scientific article published on 18 March 2015
The herpesviral antagonist m152 reveals differential activation of STING-dependent IRF and NF-κB signaling and STING's dual role during MCMV infection

scientific article published on 29 January 2019
Noncanonical expression of a murine cytomegalovirus early protein CD8 T-cell epitope as an immediate early epitope based on transcription from an upstream gene.

scientific article published on 14 February 2014
The p36 isoform of murine cytomegalovirus m152 protein suffices for mediating innate and adaptive immune evasion.

scientific article published on 16 December 2013
The Mouse Cytomegalovirus Gene m42 Targets Surface Expression of the Protein Tyrosine Phosphatase CD45 in Infected Macrophages

scientific article
Identification of an atypical CD8 T cell epitope encoded by murine cytomegalovirus ORF-M54 gaining dominance after deletion of the immunodominant antiviral CD8 T cell specificities.

scientific article published on 25 March 2015
An endocytic YXXΦ (YRRF) cargo sorting motif in the cytoplasmic tail of murine cytomegalovirus AP2 'adapter adapter' protein m04/gp34 antagonizes virus evasion of natural killer cells

scientific article
Coincident airway exposure to low-potency allergen and cytomegalovirus sensitizes for allergic airway disease by viral activation of migratory dendritic cells

scientific article published on 07 March 2019
Transcripts expressed in cytomegalovirus latency coding for an antigenic IE/E phase peptide that drives "memory inflation"

scientific article published on 19 April 2019
CD8 T-Cell Immunotherapy of Cytomegalovirus Disease in the Murine Model

Efficient Delivery of Human Cytomegalovirus T Cell Antigens by Attenuated Sendai Virus Vectors

scientific article published on 17 July 2018
Function of the cargo sorting dileucine motif in a cytomegalovirus immune evasion protein

scientific article published on 19 April 2019
Positive Role of the MHC Class-I Antigen Presentation Regulator m04/gp34 of Murine Cytomegalovirus in Antiviral Protection by CD8 T Cells

scientific article published on 26 August 2020
Eomes broadens the scope of CD8 T-cell memory by inhibiting apoptosis in cells of low affinity

scientific article published on 17 March 2020
Revisiting CD8 T-cell 'Memory Inflation': New Insights with Implications for Cytomegaloviruses as Vaccine Vectors

scientific article published on 22 July 2020
Cytomegalovirus-Associated Inhibition of Hematopoiesis Is Preventable by Cytoimmunotherapy With Antiviral CD8 T Cells

scientific article published on 21 April 2020
Advances in cytomegalovirus (CMV) biology and its relationship to health, diseases, and aging

scientific article published on 11 March 2020
The Anti-apoptotic Murine Cytomegalovirus Protein vMIA-m38.5 Induces Mast Cell Degranulation

scientific article published on 25 August 2020
Insufficient Antigen Presentation Due to Viral Immune Evasion Explains Lethal Cytomegalovirus Organ Disease After Allogeneic Hematopoietic Cell Transplantation

scientific article published on 15 April 2020
TLR3-independent activation of mast cells by cytomegalovirus contributes to control of pulmonary infection.

scientific article published on 8 May 2017
Non-cognate bystander cytolysis by clonal epitope-specific CTL lines through CD28-CD80 interaction inhibits antibody production: A potential caveat to CD8 T-cell immunotherapy.

scientific article

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