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List of works by Francesco Villa

A G613A missense in the Hutchinson's progeria lamin A/C gene causes a lone, autosomal dominant atrioventricular block

scientific article

A Model of Evolutionary Selection: The Cardiovascular Protective Function of the Longevity Associated Variant of BPIFB4

scientific article published on 19 October 2018

A rare genetic variant of BPIFB4 predisposes to high blood pressure via impairment of nitric oxide signaling.

scientific article

APOE Alleles and Extreme Human Longevity

scientific article published on 01 January 2019

Association of the FOXO3A locus with extreme longevity in a southern Italian centenarian study.

scientific article published in April 2009

Association study on long-living individuals from Southern Italy identifies rs10491334 in the CAMKIV gene that regulates survival proteins.

scientific article published on 25 May 2011

Author Correction: A rare genetic variant of BPIFB4 predisposes to high blood pressure via impairment of nitric oxide signaling

scientific article published on 28 June 2019

Centenarians as a model to discover genetic and epigenetic signatures of healthy ageing.

scientific article published on 30 October 2017

Central role of the p53 pathway in the noncoding-RNA response to oxidative stress.

scientific article published on 12 December 2017

Effects of FOXO3 Polymorphisms on Survival to Extreme Longevity in Four Centenarian Studies.

scientific article

Exome sequencing of a family with lone, autosomal dominant atrial flutter identifies a rare variation in ABCB4 significantly enriched in cases

scientific article

Four Genome-Wide Association Studies Identify New Extreme Longevity Variants

scientific article published on 15 March 2017

Genetic Analysis Reveals a Longevity-Associated Protein Modulating Endothelial Function and Angiogenesis

scientific article

LAV-BPIFB4 associates with reduced frailty in humans and its transfer prevents frailty progression in old mice

scientific article published on 28 August 2019

LAV-BPIFB4 isoform modulates eNOS signalling through Ca2+/PKC-alpha-dependent mechanism

scientific article

Longevity-Associated Variant of BPIFB4 Mitigates Monocyte-Mediated Acquired Immune Response

scientific article published on 01 November 2019

PTX3: an inflammatory protein modulating ultrastructure and bioenergetics of human endothelial cells

scientific article published on 02 February 2019

Polymorphisms of the antiapoptotic protein bag3 may play a role in the pathogenesis of tako-tsubo cardiomyopathy.

scientific article published on 11 April 2013

Serum BPIFB4 levels classify health status in long-living individuals.

scientific article published on 15 December 2015

Single systemic transfer of a human gene associated with exceptional longevity halts the progression of atherosclerosis and inflammation in ApoE knockout mice through a CXCR4-mediated mechanism

scientific article published on 10 July 2019

Taste receptors, innate immunity and longevity: the case of TAS2R16 gene

article

The application of genetics approaches to the study of exceptional longevity in humans: potential and limitations

scientific article published on 23 April 2012

The expression of the BPIFB4 and CXCR4 associates with sustained health in long-living individuals from Cilento-Italy.

scientific article published on 22 January 2017

The longevity-associated variant of BPIFB4 improves a CXCR4-mediated striatum-microglia crosstalk preventing disease progression in a mouse model of Huntington's disease

scientific article published on 18 July 2020

Vascular ageing: the role of oxidative stress.

scientific article published on 07 January 2013

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