List of works - Pawel Paszek

A method of ‘speed coefficients’ for biochemical model reduction applied to the NF-κB system ⬇️

scientific article published on February 2015

A systematic survey of the response of a model NF-κB signalling pathway to TNFα stimulation.

scientific article

Anti-inflammatory effects of infliximab in mice are independent of tumour necrosis factor α neutralization.

scientific article published on 26 September 2016

Dynamic NF-κB and E2F interactions control the priority and timing of inflammatory signalling and cell proliferation.

scientific article published on 17 May 2016

Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent models

scientific article

From measuring noise toward integrated single-cell biology

scientific article published on 19 November 2014

Heat shock response regulates stimulus-specificity and sensitivity of the pro-inflammatory NF-κB signalling

scientific article published on 24 May 2020

Inflammasome-dependent IL-1β release depends upon membrane permeabilisation

scientific article

Integration of Kinase and Calcium Signaling at the Level of Chromatin Underlies Inducible Gene Activation in T Cells

scientific article published on 13 September 2017

Interactions among oscillatory pathways in NF-kappa B signaling

scientific article

Investigating IL-1β Secretion Using Real-Time Single-Cell Imaging

scientific article

Macrophage-Specific NF-κB Activation Dynamics Can Segregate Inflammatory Bowel Disease Patients

scientific article published on 11 September 2019

Mathematical model of NF-kappaB regulatory module

scientific article

Modeling stochasticity in gene regulation: characterization in the terms of the underlying distribution function

scientific article published on 15 March 2007

Oscillatory control of signalling molecules ⬇️

scientific article published on September 17, 2010

Population robustness arising from cellular heterogeneity

scientific article

Pulsatile stimulation determines timing and specificity of NF-kappaB-dependent transcription

scientific article

Quantitative analysis of competitive cytokine signaling predicts tissue thresholds for the propagation of macrophage activation

article

Quantitative analysis reveals crosstalk mechanisms of heat shock-induced attenuation of NF-κB signaling at the single cell level.

scientific article published on 30 April 2018

Quantitative dynamic imaging of immune cell signalling using lentiviral gene transfer.

scientific article published on 20 May 2015

Signal transduction controls heterogeneous NF-κB dynamics and target gene expression through cytokine-specific refractory states

scientific article

Single TNFalpha trimers mediating NF-kappaB activation: stochastic robustness of NF-kappaB signaling.

scientific article

Stochastic effects of multiple regulators on expression profiles in eukaryotes.

scientific article published on 8 December 2004

Stochasticity in the miR-9/Hes1 oscillatory network can account for clonal heterogeneity in the timing of differentiation

scientific article published on 04 October 2016

Transcriptional stochasticity in gene expression.

scientific article published on 21 July 2005

List of works by Pawel Paszek

A method of ‘speed coefficients’ for biochemical model reduction applied to the NF-κB system ⬇️

A systematic survey of the response of a model NF-κB signalling pathway to TNFα stimulation.

Anti-inflammatory effects of infliximab in mice are independent of tumour necrosis factor α neutralization.

Dynamic NF-κB and E2F interactions control the priority and timing of inflammatory signalling and cell proliferation.

Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent models

From measuring noise toward integrated single-cell biology

Heat shock response regulates stimulus-specificity and sensitivity of the pro-inflammatory NF-κB signalling

Inflammasome-dependent IL-1β release depends upon membrane permeabilisation

Integration of Kinase and Calcium Signaling at the Level of Chromatin Underlies Inducible Gene Activation in T Cells

Interactions among oscillatory pathways in NF-kappa B signaling

Investigating IL-1β Secretion Using Real-Time Single-Cell Imaging

Macrophage-Specific NF-κB Activation Dynamics Can Segregate Inflammatory Bowel Disease Patients

Mathematical model of NF-kappaB regulatory module

Modeling stochasticity in gene regulation: characterization in the terms of the underlying distribution function

Oscillatory control of signalling molecules ⬇️

Population robustness arising from cellular heterogeneity

Pulsatile stimulation determines timing and specificity of NF-kappaB-dependent transcription

Quantitative analysis of competitive cytokine signaling predicts tissue thresholds for the propagation of macrophage activation

Quantitative analysis reveals crosstalk mechanisms of heat shock-induced attenuation of NF-κB signaling at the single cell level.

Quantitative dynamic imaging of immune cell signalling using lentiviral gene transfer.

Signal transduction controls heterogeneous NF-κB dynamics and target gene expression through cytokine-specific refractory states

Single TNFalpha trimers mediating NF-kappaB activation: stochastic robustness of NF-kappaB signaling.

Stochastic effects of multiple regulators on expression profiles in eukaryotes.

Stochasticity in the miR-9/Hes1 oscillatory network can account for clonal heterogeneity in the timing of differentiation

Transcriptional stochasticity in gene expression.