List of works - Damon Tumes

A deep convolutional neural network for segmentation of whole-slide pathology images identifies novel tumour cell-perivascular niche interactions that are associated with poor survival in glioblastoma

scientific article published on 29 April 2021

ACC1 determines memory potential of individual CD4+ T cells by regulating de novo fatty acid biosynthesis

scientific article published on 14 January 2019

Anti-βc mAb CSL311 inhibits human nasal polyp pathophysiology in a humanized mouse xenograft model

scientific article published on 03 October 2019

CD103hi Treg cells constrain lung fibrosis induced by CD103lo tissue-resident pathogenic CD4 T cells

scientific article published on 07 October 2019

DUSP10 constrains innate IL-33-mediated cytokine production in ST2 memory-type pathogenic Th2 cells

scientific article published in Nature Communications

Differential rates of apoptosis and recruitment limit eosinophil accumulation in the lungs of asthma-resistant CBA/Ca mice

scientific article published on 25 June 2008

Early-Life Antibiotic-Driven Dysbiosis Leads to Dysregulated Vaccine Immune Responses in Mice.

scientific article

Enhanced Cell Division Is Required for the Generation of Memory CD4 T Cells to Migrate Into Their Proper Location

scientific article published on 01 January 2019

Eomesodermin controls interleukin-5 production in memory T helper 2 cells through inhibition of activity of the transcription factor GATA3.

scientific article published in November 2011

Epigenetic regulation of T-helper cell differentiation, memory, and plasticity in allergic asthma.

scientific article published on July 2017

Essential Role for CD30-Transglutaminase 2 Axis in Memory Th1 and Th17 Cell Generation

scientific article published on 21 July 2020

Expression of survivin in lung eosinophils is associated with pathology in a mouse model of allergic asthma

scientific article published on 23 April 2009

Ezh2 controls development of natural killer T cells, which cause spontaneous asthma-like pathology

scientific article published on 07 March 2019

Fatty acid metabolic reprogramming via mTOR-mediated inductions of PPARγ directs early activation of T cells.

scientific article published on 30 November 2016

Functionally distinct Gata3/Chd4 complexes coordinately establish T helper 2 (Th2) cell identity

scientific article published on 7 March 2013

Immunisation with the BCG and DTPw vaccines induces different programs of trained immunity in mice

scientific article published in 2022

Memory type 2 helper T cells induce long-lasting antitumor immunity by activating natural killer cells

scientific article published on 6 June 2011

Methylation of Gata3 protein at Arg-261 regulates transactivation of the Il5 gene in T helper 2 cells

scientific article published on 10 April 2015

Multiple developmental pathways lead to the generation of CD4 T cell memory

scientific article published on 07 August 2020

Murine Schnurri-2controls natural killer cell function and lymphoma development

article

Myosin light chains 9 and 12 are functional ligands for CD69 that regulate airway inflammation.

scientific article

Obesity Drives Th17 Cell Differentiation by Inducing the Lipid Metabolic Kinase, ACC1.

scientific article published on 28 July 2015

Pathogenic memory type Th2 cells in allergic inflammation

scientific article published on 11 December 2013

Polycomb group gene product Ring1B regulates Th2-driven airway inflammation through the inhibition of Bim-mediated apoptosis of effector Th2 cells in the lung.

scientific article published on 17 March 2010

Spatial Interplay between Polycomb and Trithorax Complexes Controls Transcriptional Activity in T Lymphocytes

scientific article published on 31 August 2015

Strain-dependent resistance to allergen-induced lung pathophysiology in mice correlates with rate of apoptosis of lung-derived eosinophils

scientific article published on 22 March 2007

Th2 Cells in Health and Disease

scientific article

The immunotoxicity, but not anti-tumor efficacy, of anti-CD40 and anti-CD137 immunotherapies is dependent on the gut microbiota

scientific article published on 08 December 2021

The interleukin-33-p38 kinase axis confers memory T helper 2 cell pathogenicity in the airway.

scientific article published in February 2015

The polycomb protein Ezh2 regulates differentiation and plasticity of CD4(+) T helper type 1 and type 2 cells

scientific article

The role of invariant T cells in inflammation of the skin and airways

scientific article published on 15 April 2019

The transcription factor Sox4 is a downstream target of signaling by the cytokine TGF-β and suppresses T(H)2 differentiation

scientific article published on July 2012

Thy1+IL-7+ lymphatic endothelial cells in iBALT provide a survival niche for memory T-helper cells in allergic airway inflammation

scientific article published on 02 May 2016

Too much of a good thing

scientific article published on 01 February 2013

Toxocara canis larval excretory/secretory proteins impair eosinophil-dependent resistance of mice to Nippostrongylus brasiliensis.

scientific article

Trithorax complex component Menin controls differentiation and maintenance of T helper 17 cells.

scientific article

Type II membrane protein CD69 regulates the formation of resting T-helper memory

scientific article published on 2 April 2012

List of works by Damon Tumes

A deep convolutional neural network for segmentation of whole-slide pathology images identifies novel tumour cell-perivascular niche interactions that are associated with poor survival in glioblastoma

ACC1 determines memory potential of individual CD4+ T cells by regulating de novo fatty acid biosynthesis

Anti-βc mAb CSL311 inhibits human nasal polyp pathophysiology in a humanized mouse xenograft model

CD103hi Treg cells constrain lung fibrosis induced by CD103lo tissue-resident pathogenic CD4 T cells

DUSP10 constrains innate IL-33-mediated cytokine production in ST2 memory-type pathogenic Th2 cells

Differential rates of apoptosis and recruitment limit eosinophil accumulation in the lungs of asthma-resistant CBA/Ca mice

Early-Life Antibiotic-Driven Dysbiosis Leads to Dysregulated Vaccine Immune Responses in Mice.

Enhanced Cell Division Is Required for the Generation of Memory CD4 T Cells to Migrate Into Their Proper Location

Eomesodermin controls interleukin-5 production in memory T helper 2 cells through inhibition of activity of the transcription factor GATA3.

Epigenetic regulation of T-helper cell differentiation, memory, and plasticity in allergic asthma.

Essential Role for CD30-Transglutaminase 2 Axis in Memory Th1 and Th17 Cell Generation

Expression of survivin in lung eosinophils is associated with pathology in a mouse model of allergic asthma

Ezh2 controls development of natural killer T cells, which cause spontaneous asthma-like pathology

Fatty acid metabolic reprogramming via mTOR-mediated inductions of PPARγ directs early activation of T cells.

Functionally distinct Gata3/Chd4 complexes coordinately establish T helper 2 (Th2) cell identity

Immunisation with the BCG and DTPw vaccines induces different programs of trained immunity in mice

Memory type 2 helper T cells induce long-lasting antitumor immunity by activating natural killer cells

Methylation of Gata3 protein at Arg-261 regulates transactivation of the Il5 gene in T helper 2 cells

Multiple developmental pathways lead to the generation of CD4 T cell memory

Murine Schnurri-2controls natural killer cell function and lymphoma development

Myosin light chains 9 and 12 are functional ligands for CD69 that regulate airway inflammation.

Obesity Drives Th17 Cell Differentiation by Inducing the Lipid Metabolic Kinase, ACC1.

Pathogenic memory type Th2 cells in allergic inflammation

Polycomb group gene product Ring1B regulates Th2-driven airway inflammation through the inhibition of Bim-mediated apoptosis of effector Th2 cells in the lung.

Spatial Interplay between Polycomb and Trithorax Complexes Controls Transcriptional Activity in T Lymphocytes

Strain-dependent resistance to allergen-induced lung pathophysiology in mice correlates with rate of apoptosis of lung-derived eosinophils

Th2 Cells in Health and Disease

The immunotoxicity, but not anti-tumor efficacy, of anti-CD40 and anti-CD137 immunotherapies is dependent on the gut microbiota

The interleukin-33-p38 kinase axis confers memory T helper 2 cell pathogenicity in the airway.

The polycomb protein Ezh2 regulates differentiation and plasticity of CD4(+) T helper type 1 and type 2 cells

The role of invariant T cells in inflammation of the skin and airways

The transcription factor Sox4 is a downstream target of signaling by the cytokine TGF-β and suppresses T(H)2 differentiation

Thy1+IL-7+ lymphatic endothelial cells in iBALT provide a survival niche for memory T-helper cells in allergic airway inflammation

Too much of a good thing

Toxocara canis larval excretory/secretory proteins impair eosinophil-dependent resistance of mice to Nippostrongylus brasiliensis.

Trithorax complex component Menin controls differentiation and maintenance of T helper 17 cells.

Type II membrane protein CD69 regulates the formation of resting T-helper memory