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List of works by David A Elliott

3D aggregate culture improves metabolic maturation of human pluripotent stem cell derived cardiomyocytes

scientific article published on 27 November 2017

A targeted NKX2.1 human embryonic stem cell reporter line enables identification of human basal forebrain derivatives.

scientific article published on March 2011

A tyrosine-rich domain within homeodomain transcription factor Nkx2-5 is an essential element in the early cardiac transcriptional regulatory machinery

scientific journal article

ALPK3-deficient cardiomyocytes generated from patient-derived induced pluripotent stem cells and mutant human embryonic stem cells display abnormal calcium handling and establish that ALPK3 deficiency underlies familial cardiomyopathy.

scientific article published on 22 April 2016

Analysis of mitochondrial function and localisation during human embryonic stem cell differentiation in vitro.

scientific article

Atrial-like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial-selective pharmacology.

scientific article published on 19 February 2015

BET inhibition blocks inflammation-induced cardiac dysfunction and SARS-CoV-2 infection

scientific article published on 16 March 2021

Biomarkers of Human Pluripotent Stem Cell-Derived Cardiac Lineages.

scientific article published on 30 May 2017

CD13 and ROR2 Permit Isolation of Highly Enriched Cardiac Mesoderm from Differentiating Human Embryonic Stem Cells

scientific article published on January 2016

Cardiac Repair With a Novel Population of Mesenchymal Stem Cells Resident in the Human Heart

scientific article published on 16 July 2015

Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart

scientific journal article

Cardiac homeobox gene NKX2-5 mutations and congenital heart disease: associations with atrial septal defect and hypoplastic left heart syndrome

scientific article

Cardiac septal and valvular dysmorphogenesis in mice heterozygous for mutations in the homeobox gene Nkx2-5

scientific article published on 01 November 2000

Cardiomyocyte differentiation of pluripotent stem cells with SB203580 analogues correlates with Wnt pathway CK1 inhibition independent of p38 MAPK signaling

scientific article published on 19 December 2014

Cellular reprogramming: a new avenue to cardiac regeneration?

scientific article

Coculturing with endothelial cells promotes in vitro maturation and electrical coupling of human embryonic stem cell-derived cardiomyocytes

scientific article published on 10 January 2017

Comparing mouse and human pluripotent stem cell derived cardiac cells: Both systems have advantages for pharmacological and toxicological screening

scientific article published on 06 May 2015

Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module

scientific article

Controlling expansion and cardiomyogenic differentiation of human pluripotent stem cells in scalable suspension culture

scientific article published on 30 October 2014

Development of a human cardiac organoid injury model reveals innate regenerative potential

scientific article

Differentiation of Human Pluripotent Stem Cells to Cardiomyocytes Under Defined Conditions

scientific article

Differentiation of human embryonic stem cells and induced pluripotent stem cells to cardiomyocytes: a methods overview

scientific article

Differentiation of human embryonic stem cells to HOXA+ hemogenic vasculature that resembles the aorta-gonad-mesonephros.

scientific article published on 17 October 2016

Dual reporter MESP1 mCherry/w-NKX2-5 eGFP/w hESCs enable studying early human cardiac differentiation

scientific article published in January 2015

Evaluating anthracycline cardiotoxicity associated single nucleotide polymorphisms in a paediatric cohort with early onset cardiomyopathy

scientific article published on 21 May 2020

FOXN1 (GFP/w) reporter hESCs enable identification of integrin-β4, HLA-DR, and EpCAM as markers of human PSC-derived FOXN1(+) thymic epithelial progenitors.

scientific article

Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest.

scientific article

GAPTrap: A Simple Expression System for Pluripotent Stem Cells and Their Derivatives

scientific article published on September 2016

Genetic determinants of anthracycline cardiotoxicity - ready for the clinic?

scientific article published on 24 January 2017

Human embryonic stem cell derived mesenchymal progenitors express cardiac markers but do not form contractile cardiomyocytes.

scientific article

Independent regulation of synaptic size and activity by the anaphase-promoting complex

scientific article published in November 2004

Isogenic human pluripotent stem cell pairs reveal the role of a KCNH2 mutation in long-QT syndrome

scientific article

Isolation and characterization of human embryonic stem cell-derived heart field-specific cardiomyocytes unravels new insights into their transcriptional and electrophysiological profiles

scientific article published on 01 February 2022

Isolation and characterization of ventricular-like cells derived from NKX2-5eGFP/w and MLC2vmCherry/w double knock-in human pluripotent stem cells

scientific article published on 21 November 2017

Magnetic Resonance Imaging of Iron Oxide-Labeled Human Embryonic Stem Cell-Derived Cardiac Progenitors

scientific article

Multipotent caudal neural progenitors derived from human pluripotent stem cells that give rise to lineages of the central and peripheral nervous system.

scientific article published on June 2015

NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network

scientific article published on 10 April 2018

NKX2-5(eGFP/w) hESCs for isolation of human cardiac progenitors and cardiomyocytes.

scientific article published on 23 October 2011

PGC-1α and reactive oxygen species regulate human embryonic stem cell-derived cardiomyocyte function.

scientific article published on 12 December 2013

Publisher Correction: The role of cardiac transcription factor NKX2-5 in regulating the human cardiac miRNAome

scientific article published on 27 December 2019

SIRPA is a specific cell-surface marker for isolating cardiomyocytes derived from human pluripotent stem cells. ⬇️

scientific article published on 23 October 2011

SIRPA, VCAM1 and CD34 identify discrete lineages during early human cardiovascular development.

scientific article published on 4 May 2014

Sex-Specific Control of Human Heart Maturation by the Progesterone Receptor

scientific article published on 08 March 2021

Stem cell topography splits growth and homeostatic functions in the fish gill

scientific article published on 16 May 2019

Strategies for rapidly mapping proviral integration sites and assessing cardiogenic potential of nascent human induced pluripotent stem cell clones

scientific article published on 13 May 2014

Systematic review of pharmacogenomics and adverse drug reactions in paediatric oncology patients.

scientific article published on 29 December 2017

The GAL4 System: A Versatile Toolkit for Gene Expression in Drosophila

scientific article published on 01 July 2008

The role of cardiac transcription factor NKX2-5 in regulating the human cardiac miRNAome

scientific article published on 04 November 2019

The use of agarose microwells for scalable embryoid body formation and cardiac differentiation of human and murine pluripotent stem cells

scientific article published on 16 January 2013

Time to mend a broken heart

scientific article published on 17 September 2007

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