List of works - Alison Gartland

A Candidate Gene Association Study of Bone Mineral Density in an Iranian Population

scientific article published on 27 October 2016

A new histomorphometric method to assess growth plate chondrodysplasia and its application to the toothless (tl, Csf1(null)) osteopetrotic rat.

scientific article published in January 2004

Adenosine triphosphate stimulates human osteoclast activity via upregulation of osteoblast-expressed receptor activator of nuclear factor-kappa B ligand

scientific article published in November 2002

Application of multiple forms of mechanical loading to human osteoblasts reveals increased ATP release in response to fluid flow in 3D cultures and differential regulation of immediate early genes.

scientific article

Bone phenotypes of P2 receptor knockout mice.

scientific article published in June 2011

Bone turnover is altered in transgenic rats overexpressing the P2Y2 purinergic receptor

scientific article

Cobalt and chromium exposure affects osteoblast function and impairs the mineralization of prosthesis surfaces in vitro

scientific article published on 30 April 2015

Dataset for the proteomic inventory and quantitative analysis of the breast cancer hypoxic secretome associated with osteotropism

scientific article published on 23 October 2015

Editorial overview: Musculoskeletal: Are we on the road to personalised medicine in musculoskeletal diseases?

scholarly article by Alison Gartland & Lynne J Hocking published June 2014 in Current Opinion in Pharmacology

Effects of chronic cobalt and chromium exposure after metal-on-metal hip resurfacing: An epigenome-wide association pilot study

scientific article published on 18 January 2017

Effects of cobalt and chromium ions at clinically equivalent concentrations after metal-on-metal hip replacement on human osteoblasts and osteoclasts: Implications for skeletal health

article

Extracellular nucleotide signaling: a mechanism for integrating local and systemic responses in the activation of bone remodeling

scientific article (publication date: May 2001)

Functional polymorphisms in the P2X7 receptor gene are associated with stress fracture injury

scientific article published on 29 January 2016

Generation of a novel mouse model for the inducible depletion of macrophages in vivo

scientific article published on 20 September 2012

Genetic Background Strongly Influences the Bone Phenotype of P2X7 Receptor Knockout Mice

scientific article

Human Osteoclast Culture and Phenotypic Characterization

article

In vitro chondrocyte differentiation using costochondral chondrocytes as a source of primary rat chondrocyte cultures: an improved isolation and cryopreservation method.

scientific article

Isolation and culture of human osteoblasts

article

LOXL2-mediated matrix remodeling in metastasis and mammary gland involution

scientific article published on 13 January 2011

Lysyl Oxidase, a Targetable Secreted Molecule Involved in Cancer Metastasis

scientific article

Osteocyte physiology and response to fluid shear stress are impaired following exposure to cobalt and chromium: Implications for bone health following joint replacement

scientific article published on 27 September 2016

P2 receptors in bone--modulation of osteoclast formation and activity via P2X7 activation

scientific article (publication date: 2003)

P2X7 receptor regulates osteoclast function and bone loss in a mouse model of osteoporosis.

scientific article published on 22 February 2018

P2X7 receptors: role in bone cell formation and function

scientific article

PPAR agonists modulate human osteoclast formation and activity in vitro

scientific article published on 28 September 2006

Polymorphisms in the P2X7 receptor gene are associated with low lumbar spine bone mineral density and accelerated bone loss in post-menopausal women

scientific article

Primary human osteoblast cultures.

scientific article

Purinergic signalling in bone

scientific article (publication date: 2012)

Purinergic signalling in osteoblasts.

scientific article published on January 2012

RSPO2 and RANKL signal through LGR4 to regulate osteoclastic premetastatic niche formation and bone metastasis

scientific article published in 2022

Reduced bone turnover in mice lacking the P2Y13 receptor of ADP.

scientific article

Role of purinergic receptor polymorphisms in human bone.

scientific article published on June 2011

Role of the P2X7 receptor in the osteogenic differentiation of mesenchymal cells and in osteoclast fusion : presented by: Maria P. Abbracchio.

scientific article published on September 2013

Role of the P2Y13 receptor in the differentiation of bone marrow stromal cells into osteoblasts and adipocytes

scientific article

Septoclast deficiency accompanies postnatal growth plate chondrodysplasia in the toothless (tl) osteopetrotic, colony-stimulating factor-1 (CSF-1)-deficient rat and is partially responsive to CSF-1 injections

scientific journal article

Simulated Interventions to Ameliorate Age-Related Bone Loss Indicate the Importance of Timing

scientific article published on 13 June 2016

Single-nucleotide polymorphisms in the P2X7 receptor gene are associated with post-menopausal bone loss and vertebral fractures

scientific article

Targeting P2 receptors--current progress in treating musculoskeletal diseases

scientific article published on 28 May 2014

The P2Y(6) receptor stimulates bone resorption by osteoclasts.

scientific article published on 9 August 2011

The P2Y13 receptor regulates extracellular ATP metabolism and the osteogenic response to mechanical loading.

scientific article

The P2Y13 receptor regulates phosphate metabolism and FGF-23 secretion with effects on skeletal development

article

The effects of P2X7 receptor antagonists on the formation and function of human osteoclasts in vitro

scientific article published on 21 April 2010

The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase.

scientific article published on 27 May 2015

The pre-metastatic niche: is metastasis random?

scientific article

The role of lysyl oxidase, the extracellular matrix and the pre-metastatic niche in bone metastasis

scientific article

Trophic activity of human P2X7 receptor isoforms A and B in osteosarcoma.

scientific article

Understanding the tissue effects of tribo-corrosion: uptake, distribution, and speciation of cobalt and chromium in human bone cells

scientific article

List of works by Alison Gartland

A Candidate Gene Association Study of Bone Mineral Density in an Iranian Population

A new histomorphometric method to assess growth plate chondrodysplasia and its application to the toothless (tl, Csf1(null)) osteopetrotic rat.

Adenosine triphosphate stimulates human osteoclast activity via upregulation of osteoblast-expressed receptor activator of nuclear factor-kappa B ligand

Application of multiple forms of mechanical loading to human osteoblasts reveals increased ATP release in response to fluid flow in 3D cultures and differential regulation of immediate early genes.

Bone phenotypes of P2 receptor knockout mice.

Bone turnover is altered in transgenic rats overexpressing the P2Y2 purinergic receptor

Cobalt and chromium exposure affects osteoblast function and impairs the mineralization of prosthesis surfaces in vitro

Dataset for the proteomic inventory and quantitative analysis of the breast cancer hypoxic secretome associated with osteotropism

Editorial overview: Musculoskeletal: Are we on the road to personalised medicine in musculoskeletal diseases?

Effects of chronic cobalt and chromium exposure after metal-on-metal hip resurfacing: An epigenome-wide association pilot study

Effects of cobalt and chromium ions at clinically equivalent concentrations after metal-on-metal hip replacement on human osteoblasts and osteoclasts: Implications for skeletal health

Extracellular nucleotide signaling: a mechanism for integrating local and systemic responses in the activation of bone remodeling

Functional polymorphisms in the P2X7 receptor gene are associated with stress fracture injury

Generation of a novel mouse model for the inducible depletion of macrophages in vivo

Genetic Background Strongly Influences the Bone Phenotype of P2X7 Receptor Knockout Mice

Human Osteoclast Culture and Phenotypic Characterization

In vitro chondrocyte differentiation using costochondral chondrocytes as a source of primary rat chondrocyte cultures: an improved isolation and cryopreservation method.

Isolation and culture of human osteoblasts

LOXL2-mediated matrix remodeling in metastasis and mammary gland involution

Lysyl Oxidase, a Targetable Secreted Molecule Involved in Cancer Metastasis

Osteocyte physiology and response to fluid shear stress are impaired following exposure to cobalt and chromium: Implications for bone health following joint replacement

P2 receptors in bone--modulation of osteoclast formation and activity via P2X7 activation

P2X7 receptor regulates osteoclast function and bone loss in a mouse model of osteoporosis.

P2X7 receptors: role in bone cell formation and function

PPAR agonists modulate human osteoclast formation and activity in vitro

Polymorphisms in the P2X7 receptor gene are associated with low lumbar spine bone mineral density and accelerated bone loss in post-menopausal women

Primary human osteoblast cultures.

Purinergic signalling in bone

Purinergic signalling in osteoblasts.

RSPO2 and RANKL signal through LGR4 to regulate osteoclastic premetastatic niche formation and bone metastasis

Reduced bone turnover in mice lacking the P2Y13 receptor of ADP.

Role of purinergic receptor polymorphisms in human bone.

Role of the P2X7 receptor in the osteogenic differentiation of mesenchymal cells and in osteoclast fusion : presented by: Maria P. Abbracchio.

Role of the P2Y13 receptor in the differentiation of bone marrow stromal cells into osteoblasts and adipocytes

Septoclast deficiency accompanies postnatal growth plate chondrodysplasia in the toothless (tl) osteopetrotic, colony-stimulating factor-1 (CSF-1)-deficient rat and is partially responsive to CSF-1 injections

Simulated Interventions to Ameliorate Age-Related Bone Loss Indicate the Importance of Timing

Single-nucleotide polymorphisms in the P2X7 receptor gene are associated with post-menopausal bone loss and vertebral fractures

Targeting P2 receptors--current progress in treating musculoskeletal diseases

The P2Y(6) receptor stimulates bone resorption by osteoclasts.

The P2Y13 receptor regulates extracellular ATP metabolism and the osteogenic response to mechanical loading.

The P2Y13 receptor regulates phosphate metabolism and FGF-23 secretion with effects on skeletal development

The effects of P2X7 receptor antagonists on the formation and function of human osteoclasts in vitro

The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase.

The pre-metastatic niche: is metastasis random?

The role of lysyl oxidase, the extracellular matrix and the pre-metastatic niche in bone metastasis

Trophic activity of human P2X7 receptor isoforms A and B in osteosarcoma.

Understanding the tissue effects of tribo-corrosion: uptake, distribution, and speciation of cobalt and chromium in human bone cells