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List of works by Gaynor A Smith

A Nurr1 agonist causes neuroprotection in a Parkinson's disease lesion model primed with the toll-like receptor 3 dsRNA inflammatory stimulant poly(I:C).

scientific article

ALS-associated peripherin spliced transcripts form distinct protein inclusions that are neuroprotective against oxidative stress

scientific article

Amphetamine-induced dyskinesia in the transplanted hemi-Parkinsonian mouse.

scientific article published on January 2012

Amphetamine-induced rotation in the transplanted hemi-parkinsonian rat – Response to pharmacological modulation ⬇️

scientific article published on April 9, 2012

Chronic administration of Dimebon does not ameliorate amyloid-β pathology in 5xFAD transgenic mice.

scientific article

Comparison of 6‐hydroxydopamine lesions of the substantia nigra and the medial forebrain bundle on a lateralised choice reaction time task in mice ⬇️

scientific article published on November 1, 2012

Context-driven changes in L-DOPA-induced behaviours in the 6-OHDA lesioned rat.

scientific article published on 8 January 2011

Enhanced ubiquitin-dependent degradation by Nedd4 protects against α-synuclein accumulation and toxicity in animal models of Parkinson's disease.

scientific article published on 31 December 2013

Fibroblast Biomarkers of Sporadic Parkinson's Disease and LRRK2 Kinase Inhibition.

scientific article published on 23 September 2015

Glucocerebrosidase gene therapy prevents α-synucleinopathy of midbrain dopamine neurons

scientific journal article

Glutathione S-Transferase Regulates Mitochondrial Populations in Axons through Increased Glutathione Oxidation

scientific article published on 14 May 2019

Increased efficacy of the 6-hydroxydopamine lesion of the median forebrain bundle in small rats, by modification of the stereotaxic coordinates.

scientific article

Influence of chronic L-DOPA treatment on immune response following allogeneic and xenogeneic graft in a rat model of Parkinson's disease ⬇️

scientific article

Pharmacological modulation of amphetamine-induced dyskinesia in transplanted hemi-parkinsonian rats.

scientific article published on 18 June 2012

Progressive axonal transport and synaptic protein changes correlate with behavioral and neuropathological abnormalities in the heterozygous Q175 KI mouse model of Huntington's disease

scientific article published on 12 April 2014

Progressive decline of glucocerebrosidase in aging and Parkinson's disease.

scientific article

Successful function of autologous iPSC-derived dopamine neurons following transplantation in a non-human primate model of Parkinson's disease

scientific article published on 26 February 2015

Sustained Systemic Glucocerebrosidase Inhibition Induces Brain α-Synuclein Aggregation, Microglia and Complement C1q Activation in Mice

scientific article

The search for genetic mouse models of prodromal Parkinson's disease.

scientific article published on 14 July 2012

Two cells are better than one: optimizing stem cell survival by co-grafting "helper" cells that offer regulated trophic support.

scientific article published on 12 July 2013

Understanding graft-induced dyskinesia.

scientific article published on September 2010

Unilateral nigrostriatal 6-hydroxydopamine lesions in mice II: Predicting l-DOPA-induced dyskinesia ⬇️

scientific article published on September 19, 2011

Using Drosophila models of Huntington's disease as a translatable tool

scientific article published in August 2015

Widespread neuron-specific transgene expression in brain and spinal cord following synapsin promoter-driven AAV9 neonatal intracerebroventricular injection.

scientific article published on 29 May 2014

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