List of works - Thomas Herrmann

A Photo-Crosslinkable Biotin Derivative of the Phosphoantigen (E)-4-Hydroxy-3-Methylbut-2-Enyl Diphosphate (HMBPP) Activates Vγ9Vδ2 T Cells and Binds to the HMBPP Site of BTN3A1.

scientific article

A glance over the fence: Using phylogeny and species comparison for a better understanding of antigen recognition by human γδ T-cells

scientific article published on 27 September 2020

A polymorphism of the rat T-cell receptor beta-chain variable gene 13 (BV13S1) correlates with the frequency of BV13S1-positive CD4 cells

scientific article published in April 2000

Ablation of T cell immunity differentially influences tumor risk in inbred BD rat strains

scientific article published on 13 January 2009

Alpaca (Vicugna pacos), the first nonprimate species with a phosphoantigen-reactive Vγ9Vδ2 T cell subset

scientific article published on 05 March 2020

B7-H1-deficiency enhances the potential of tolerogenic dendritic cells by activating CD1d-restricted type II NKT cells

scientific article

Butyrophilin 3A (BTN3A, CD277)-specific antibody 20.1 differentially activates Vγ9Vδ2 TCR clonotypes and interferes with phosphoantigen activation

scientific article published on 6 April 2017

CD1d expression in paneth cells and rat exocrine pancreas revealed by novel monoclonal antibodies which differentially affect NKT cell activation

scientific article

CD8⁺ T cell help is required for efficient induction of EAE in Lewis rats

scientific article published on 7 May 2013

Characterization of a new mouse model for peripheral T cell lymphoma in humans

scientific article

Contrasting contributions of complementarity-determining region 2 and hypervariable region 4 of rat BV8S2+ (Vbeta8.2) TCR to the recognition of myelin basic protein and different types of bacterial superantigens

scientific article published on 29 March 2004

Control of TCR V alpha-mediated positive repertoire selection and alloreactivity by differential J alpha usage and CDR3 alpha composition

scientific article published in October 1997

Control of Toxoplasma gondii infection by athymic LEW-Whnrnurats

scientific article published on 21 April 2008

Demonstration of two distinct forms of released low-affinity type interleukin 2 receptors

scientific article published in November 1988

Different manifestations of Toxoplasma gondii infection in F344 and LEW rats

scientific article published in March 1999

Differential CD4/CD8 subset-specific expression of highly homologous rat Tcrb-V8 family members suggests a role of CDR2 and/or CDR4 (HV4) in MHC class-specific thymic selection

scientific article published on 01 March 1999

Differential modulation of CD8beta by rat gammadelta and alphabeta T cells after activation

scientific article

Direct identification of rat iNKT cells reveals remarkable similarities to human iNKT cells and a profound deficiency in LEW rats

scientific article published on 26 December 2012

Enhanced glucocorticoid receptor signaling in T cells impacts thymocyte apoptosis and adaptive immune responses

scientific article published on March 2007

Establishment of a vascular endothelial cell-reactive type II NKT cell clone from a rat model of autoimmune vasculitis

scientific article published on 19 September 2014

Expression of functional CD8alpha Beta heterodimer on rat gamma delta T cells does not correlate with the CDR3 length of the TCR delta chain predicted for MHC class I-restricted antigen recognition

scientific article published in December 2000

Function and expression of CD1d and invariant natural killer T-cell receptor in the cotton rat (Sigmodon hispidus).

scientific article published on 8 September 2015

In vivo responses of CD4+ and CD8+ cells to bacterial superantigens

scientific article published in July 1992

Inhibition of phosphoantigen-mediated gammadelta T-cell proliferation by CD4+ CD25+ FoxP3+ regulatory T cells

scientific article

Key implication of CD277/butyrophilin-3 (BTN3A) in cellular stress sensing by a major human γδ T-cell subset

scientific article

Modulation of experimental autoimmune encephalomyelitis by administration of cells expressing antigenic peptide covalently linked to MHC class II.

scientific article published on July 2004

Monovalent antibody scFv fragments selected to modulate T-cell activation by inhibition of CD86-CD28 interaction

scientific journal article

Normal clonal expansion but impaired Fas-mediated cell death and anergy induction in interleukin-2-deficient mice

scientific article published in September 1995

Peripheral T-cell reactivity to bacterial superantigens in vivo: the response/anergy paradox.

scientific article

Polyinosinic-polycytidylic acid-mediated stimulation of human gammadelta T cells via CD11c dendritic cell-derived type I interferons

scientific article

Preferential TCR V usage in rat repertoire selection: Vα8 imparts both positive thymic selection by and alloreactivity to RT1f

scientific article published on 01 September 1994

Prevention of type 1 diabetes in the rat with an allele-specific anti-T-cell receptor antibody: Vβ13 as a therapeutic target and biomarker

scientific article published on 24 February 2012

Reduced expression of the mevalonate pathway enzyme farnesyl pyrophosphate synthase unveils recognition of tumor cells by Vgamma9Vdelta2 T cells

scientific article

Robust 8-color flow cytometry panel reveals enhanced effector function of NKG2C+ CD57+ FcεRγ- NK cells in CMV seropositive human blood donors

scientific article

Species Specific Differences of CD1d Oligomer Loading In Vitro

scientific article published on 24 November 2015

Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome

scientific article

Superantigen-presentation by rat major histocompatibility complex class II molecules RT1.Bl and RT1.Dl

scientific article published on 24 December 2008

Superantigens

Synergistic targeting of breast cancer stem-like cells by human γδ T cells and CD8+ T cells.

scientific article published on 30 March 2017

TCR repertoire analysis reveals phosphoantigen-induced polyclonal proliferation of Vγ9Vδ2 T cells in neonates and adults

scientific article published on 17 February 2020

Tandem repeats modify the structure of the canine CD1D gene.

scientific article published on 19 September 2012

The Armadillo (Dasypus novemcinctus): A Witness but Not a Functional Example for the Emergence of the Butyrophilin 3/Vγ9Vδ2 System in Placental Mammals.

scientific article

The CD8 T cell response to staphylococcal enterotoxins.

scientific article

The Forgotten: Identification and Functional Characterization of MHC Class II Molecules H2-Eb2 and RT1-Db2.

scientific article published on 06 January 2016

The Vγ9Vδ2 T Cell Antigen Receptor and Butyrophilin-3 A1: Models of Interaction, the Possibility of Co-Evolution, and the Case of Dendritic Epidermal T Cells

scientific article

The canonical T cell receptor of dendritic epidermal γδ T cells is highly conserved between rats and mice

scientific article published on 01 December 1996

The endogenous danger signals HSP70 and MICA cooperate in the activation of cytotoxic effector functions of NK cells.

scientific article published on April 2010

The high affinity interleukin 2 receptor: evidence for three distinct polypeptide chains comprising the high affinity interleukin 2 receptor

scientific article published in November 1988

The human intermediate-affinity interleukin 2 receptor consists of two distinct, partially homologous glycoproteins

scientific article

The hypervariable region 4 (HV4) and position 93 of the α chain modulate CD1d-glycolipid binding of iNKT TCRs.

scientific article published on 12 May 2015

The intermediate-affinity interleukin (IL)2 receptor expressed on Theileria annulata-infected cells comprises a single IL 2-binding protein. Partial characterization of bovine IL2 receptors

scientific article published in July 1989

The viral superantigen Mls-1a induces interferon-gamma secretion by specifically primed CD8+ cells but fails to trigger cytotoxicity.

scientific article

Thymic development and repertoire selection: the rat perspective.

scientific article

Vγ9 and Vδ2 T cell antigen receptor genes and butyrophilin 3 (BTN3) emerged with placental mammals and are concomitantly preserved in selected species like alpaca (Vicugna pacos).

scientific article published on 14 February 2014

Vγ9Vδ2 TCR-activation by phosphorylated antigens requires butyrophilin 3 A1 (BTN3A1) and additional genes on human chromosome 6.

scientific article published on 30 June 2014

List of works by Thomas Herrmann

A Photo-Crosslinkable Biotin Derivative of the Phosphoantigen (E)-4-Hydroxy-3-Methylbut-2-Enyl Diphosphate (HMBPP) Activates Vγ9Vδ2 T Cells and Binds to the HMBPP Site of BTN3A1.

A glance over the fence: Using phylogeny and species comparison for a better understanding of antigen recognition by human γδ T-cells

A polymorphism of the rat T-cell receptor beta-chain variable gene 13 (BV13S1) correlates with the frequency of BV13S1-positive CD4 cells

Ablation of T cell immunity differentially influences tumor risk in inbred BD rat strains

Alpaca (Vicugna pacos), the first nonprimate species with a phosphoantigen-reactive Vγ9Vδ2 T cell subset

B7-H1-deficiency enhances the potential of tolerogenic dendritic cells by activating CD1d-restricted type II NKT cells

Butyrophilin 3A (BTN3A, CD277)-specific antibody 20.1 differentially activates Vγ9Vδ2 TCR clonotypes and interferes with phosphoantigen activation

CD1d expression in paneth cells and rat exocrine pancreas revealed by novel monoclonal antibodies which differentially affect NKT cell activation

CD8⁺ T cell help is required for efficient induction of EAE in Lewis rats

Characterization of a new mouse model for peripheral T cell lymphoma in humans

Contrasting contributions of complementarity-determining region 2 and hypervariable region 4 of rat BV8S2+ (Vbeta8.2) TCR to the recognition of myelin basic protein and different types of bacterial superantigens

Control of TCR V alpha-mediated positive repertoire selection and alloreactivity by differential J alpha usage and CDR3 alpha composition

Control of Toxoplasma gondii infection by athymic LEW-Whnrnurats

Demonstration of two distinct forms of released low-affinity type interleukin 2 receptors

Different manifestations of Toxoplasma gondii infection in F344 and LEW rats

Differential CD4/CD8 subset-specific expression of highly homologous rat Tcrb-V8 family members suggests a role of CDR2 and/or CDR4 (HV4) in MHC class-specific thymic selection

Differential modulation of CD8beta by rat gammadelta and alphabeta T cells after activation

Direct identification of rat iNKT cells reveals remarkable similarities to human iNKT cells and a profound deficiency in LEW rats

Enhanced glucocorticoid receptor signaling in T cells impacts thymocyte apoptosis and adaptive immune responses

Establishment of a vascular endothelial cell-reactive type II NKT cell clone from a rat model of autoimmune vasculitis

Expression of functional CD8alpha Beta heterodimer on rat gamma delta T cells does not correlate with the CDR3 length of the TCR delta chain predicted for MHC class I-restricted antigen recognition

Function and expression of CD1d and invariant natural killer T-cell receptor in the cotton rat (Sigmodon hispidus).

In vivo responses of CD4+ and CD8+ cells to bacterial superantigens

Inhibition of phosphoantigen-mediated gammadelta T-cell proliferation by CD4+ CD25+ FoxP3+ regulatory T cells

Key implication of CD277/butyrophilin-3 (BTN3A) in cellular stress sensing by a major human γδ T-cell subset

Modulation of experimental autoimmune encephalomyelitis by administration of cells expressing antigenic peptide covalently linked to MHC class II.

Monovalent antibody scFv fragments selected to modulate T-cell activation by inhibition of CD86-CD28 interaction

Normal clonal expansion but impaired Fas-mediated cell death and anergy induction in interleukin-2-deficient mice

Peripheral T-cell reactivity to bacterial superantigens in vivo: the response/anergy paradox.

Polyinosinic-polycytidylic acid-mediated stimulation of human gammadelta T cells via CD11c dendritic cell-derived type I interferons

Preferential TCR V usage in rat repertoire selection: Vα8 imparts both positive thymic selection by and alloreactivity to RT1f

Prevention of type 1 diabetes in the rat with an allele-specific anti-T-cell receptor antibody: Vβ13 as a therapeutic target and biomarker

Reduced expression of the mevalonate pathway enzyme farnesyl pyrophosphate synthase unveils recognition of tumor cells by Vgamma9Vdelta2 T cells

Robust 8-color flow cytometry panel reveals enhanced effector function of NKG2C+ CD57+ FcεRγ- NK cells in CMV seropositive human blood donors

Species Specific Differences of CD1d Oligomer Loading In Vitro

Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome

Superantigen-presentation by rat major histocompatibility complex class II molecules RT1.Bl and RT1.Dl

Superantigens

Synergistic targeting of breast cancer stem-like cells by human γδ T cells and CD8+ T cells.

TCR repertoire analysis reveals phosphoantigen-induced polyclonal proliferation of Vγ9Vδ2 T cells in neonates and adults

Tandem repeats modify the structure of the canine CD1D gene.

The Armadillo (Dasypus novemcinctus): A Witness but Not a Functional Example for the Emergence of the Butyrophilin 3/Vγ9Vδ2 System in Placental Mammals.

The CD8 T cell response to staphylococcal enterotoxins.

The Forgotten: Identification and Functional Characterization of MHC Class II Molecules H2-Eb2 and RT1-Db2.

The Vγ9Vδ2 T Cell Antigen Receptor and Butyrophilin-3 A1: Models of Interaction, the Possibility of Co-Evolution, and the Case of Dendritic Epidermal T Cells

The canonical T cell receptor of dendritic epidermal γδ T cells is highly conserved between rats and mice

The endogenous danger signals HSP70 and MICA cooperate in the activation of cytotoxic effector functions of NK cells.

The high affinity interleukin 2 receptor: evidence for three distinct polypeptide chains comprising the high affinity interleukin 2 receptor

The human intermediate-affinity interleukin 2 receptor consists of two distinct, partially homologous glycoproteins

The hypervariable region 4 (HV4) and position 93 of the α chain modulate CD1d-glycolipid binding of iNKT TCRs.

The intermediate-affinity interleukin (IL)2 receptor expressed on Theileria annulata-infected cells comprises a single IL 2-binding protein. Partial characterization of bovine IL2 receptors

The viral superantigen Mls-1a induces interferon-gamma secretion by specifically primed CD8+ cells but fails to trigger cytotoxicity.

Thymic development and repertoire selection: the rat perspective.

Vγ9 and Vδ2 T cell antigen receptor genes and butyrophilin 3 (BTN3) emerged with placental mammals and are concomitantly preserved in selected species like alpaca (Vicugna pacos).

Vγ9Vδ2 TCR-activation by phosphorylated antigens requires butyrophilin 3 A1 (BTN3A1) and additional genes on human chromosome 6.