List of works - Christopher V. Carman

A small molecule agonist of an integrin, alphaLbeta2.

scientific article

A transmigratory cup in leukocyte diapedesis both through individual vascular endothelial cells and between them

scientific article

Actin foci facilitate activation of the phospholipase C-γ in primary T lymphocytes via the WASP pathway

scientific article

Activation-induced conformational changes in the I domain region of lymphocyte function-associated antigen 1.

scientific article published on 15 January 2002

Active Rap1, a small GTPase that induces malignant transformation of hematopoietic progenitors, localizes in the nucleus and regulates protein expression.

scientific article published on May 2007

Antigen Recognition Is Facilitated by Invadosome-like Protrusions Formed by Memory/Effector T Cells ⬇️

scientific article published on March 21, 2012

Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins

scientific article published in September 2003

Binding and phosphorylation of tubulin by G protein-coupled receptor kinases

scientific article

Cdc42 interacting protein 4 (CIP4) is essential for integrin-dependent T-cell trafficking.

scientific article

Cellular and extracellular programming of cell fate through engineered intracrine-, paracrine-, and endocrine-like mechanisms

scientific article

Central role for hydrogen peroxide in P2Y1 ADP receptor-mediated cellular responses in vascular endothelium

scientific article published on 18 February 2014

Dimerization and the effectiveness of ICAM-1 in mediating LFA-1-dependent adhesion

scientific article published in June 2001

Directed evolution to probe protein allostery and integrin I domains of 200,000-fold higher affinity.

scholarly article

Disrupting integrin transmembrane domain heterodimerization increases ligand binding affinity, not valency or clustering.

scientific article

ERG is required for the differentiation of embryonic stem cells along the endothelial lineage

scientific article published on 23 December 2009

ETS-related gene (ERG) controls endothelial cell permeability via transcriptional regulation of the claudin 5 (CLDN5) gene

scientific journal article

Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression

scientific article (publication date: 31 July 2003)

G-protein-coupled receptors: turn-ons and turn-offs

scientific article

Glassy dynamics, cell mechanics, and endothelial permeability

scientific article published on 30 May 2013

High-resolution fluorescence microscopy to study transendothelial migration.

scientific article published in January 2012

Integrin avidity regulation: are changes in affinity and conformation underemphasized?

scientific article (publication date: October 2003)

Intravital imaging of mesenchymal stem cell trafficking and association with platelets and neutrophils.

scientific article

Mechanisms for transcellular diapedesis: probing and pathfinding by 'invadosome-like protrusions'.

scientific article published on September 2009

Mesenchymal stem cells transmigrate between and directly through tumor necrosis factor-α-activated endothelial cells via both leukocyte-like and novel mechanisms

scientific article

Mutational analysis of Gbetagamma and phospholipid interaction with G protein-coupled receptor kinase 2

scientific article (publication date: 7 April 2000)

Novel role of CD47 in rat microvascular endothelium: signaling and regulation of T-cell transendothelial migration.

scientific article

Overview: Imaging in the Study of Integrins ⬇️

scientific article published on January 1, 2012

Probing the biomechanical contribution of the endothelium to lymphocyte migration: diapedesis by the path of least resistance.

scientific article

RIAM, an Ena/VASP and Profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion

scientific article

Regulation of outside-in signaling and affinity by the beta2 I domain of integrin alphaLbeta2.

scholarly article

Release of cellular tension signals self-restorative ventral lamellipodia to heal barrier micro-wounds.

scientific article

Role of BRAFV600E in the first preclinical model of multifocal infiltrating myopericytoma development and microenvironment

scientific article

Selective gene silencing in activated leukocytes by targeting siRNAs to the integrin lymphocyte function-associated antigen-1.

scholarly article

Selective regulation of Galpha(q/11) by an RGS domain in the G protein-coupled receptor kinase, GRK2

scientific journal article

Soluble adhesion molecules as markers for sepsis and the potential pathophysiological discrepancy in neonates, children and adults

scientific article

Specific and covalent labeling of a membrane protein with organic fluorochromes and quantum dots

scientific article

Structural basis of integrin regulation and signaling

scientific article (publication date: 2007)

Structure-function analysis of G protein-coupled receptor kinase-5. Role of the carboxyl terminus in kinase regulation

scientific article

Substrate stiffening promotes endothelial monolayer disruption through enhanced physical forces

scientific article published on 22 September 2010

Teasing out monocyte trafficking mechanisms

scientific article published on 01 August 2008

The primacy of affinity over clustering in regulation of adhesiveness of the integrin {alpha}L{beta}2.

scientific article

The receptor PD-1 controls follicular regulatory T cells in the lymph nodes and blood.

scientific article published on 16 December 2012

Transition from rolling to firm adhesion is regulated by the conformation of the I domain of the integrin lymphocyte function-associated antigen-1.

scientific article published on 3 October 2002

Tumor-Derived Extracellular Vesicles Breach the Intact Blood-Brain Barrier via Transcytosis

scientific article published on 10 September 2019

Ultrastructure and function of dimeric, soluble intercellular adhesion molecule-1 (ICAM-1).

scientific article published on 4 June 2001

List of works by Christopher V. Carman

A small molecule agonist of an integrin, alphaLbeta2.

A transmigratory cup in leukocyte diapedesis both through individual vascular endothelial cells and between them

Actin foci facilitate activation of the phospholipase C-γ in primary T lymphocytes via the WASP pathway

Activation-induced conformational changes in the I domain region of lymphocyte function-associated antigen 1.

Active Rap1, a small GTPase that induces malignant transformation of hematopoietic progenitors, localizes in the nucleus and regulates protein expression.

Antigen Recognition Is Facilitated by Invadosome-like Protrusions Formed by Memory/Effector T Cells ⬇️

Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins

Binding and phosphorylation of tubulin by G protein-coupled receptor kinases

Cdc42 interacting protein 4 (CIP4) is essential for integrin-dependent T-cell trafficking.

Cellular and extracellular programming of cell fate through engineered intracrine-, paracrine-, and endocrine-like mechanisms

Central role for hydrogen peroxide in P2Y1 ADP receptor-mediated cellular responses in vascular endothelium

Dimerization and the effectiveness of ICAM-1 in mediating LFA-1-dependent adhesion

Directed evolution to probe protein allostery and integrin I domains of 200,000-fold higher affinity.

Disrupting integrin transmembrane domain heterodimerization increases ligand binding affinity, not valency or clustering.

ERG is required for the differentiation of embryonic stem cells along the endothelial lineage

ETS-related gene (ERG) controls endothelial cell permeability via transcriptional regulation of the claudin 5 (CLDN5) gene

Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression

G-protein-coupled receptors: turn-ons and turn-offs

Glassy dynamics, cell mechanics, and endothelial permeability

High-resolution fluorescence microscopy to study transendothelial migration.

Integrin avidity regulation: are changes in affinity and conformation underemphasized?

Intravital imaging of mesenchymal stem cell trafficking and association with platelets and neutrophils.

Mechanisms for transcellular diapedesis: probing and pathfinding by 'invadosome-like protrusions'.

Mesenchymal stem cells transmigrate between and directly through tumor necrosis factor-α-activated endothelial cells via both leukocyte-like and novel mechanisms

Mutational analysis of Gbetagamma and phospholipid interaction with G protein-coupled receptor kinase 2

Novel role of CD47 in rat microvascular endothelium: signaling and regulation of T-cell transendothelial migration.

Overview: Imaging in the Study of Integrins ⬇️

Probing the biomechanical contribution of the endothelium to lymphocyte migration: diapedesis by the path of least resistance.

RIAM, an Ena/VASP and Profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion

Regulation of outside-in signaling and affinity by the beta2 I domain of integrin alphaLbeta2.

Release of cellular tension signals self-restorative ventral lamellipodia to heal barrier micro-wounds.

Role of BRAFV600E in the first preclinical model of multifocal infiltrating myopericytoma development and microenvironment

Selective gene silencing in activated leukocytes by targeting siRNAs to the integrin lymphocyte function-associated antigen-1.

Selective regulation of Galpha(q/11) by an RGS domain in the G protein-coupled receptor kinase, GRK2

Soluble adhesion molecules as markers for sepsis and the potential pathophysiological discrepancy in neonates, children and adults

Specific and covalent labeling of a membrane protein with organic fluorochromes and quantum dots

Structural basis of integrin regulation and signaling

Structure-function analysis of G protein-coupled receptor kinase-5. Role of the carboxyl terminus in kinase regulation

Substrate stiffening promotes endothelial monolayer disruption through enhanced physical forces

Teasing out monocyte trafficking mechanisms

The primacy of affinity over clustering in regulation of adhesiveness of the integrin {alpha}L{beta}2.

The receptor PD-1 controls follicular regulatory T cells in the lymph nodes and blood.

Transition from rolling to firm adhesion is regulated by the conformation of the I domain of the integrin lymphocyte function-associated antigen-1.

Tumor-Derived Extracellular Vesicles Breach the Intact Blood-Brain Barrier via Transcytosis

Ultrastructure and function of dimeric, soluble intercellular adhesion molecule-1 (ICAM-1).