List of works - Xavier Trepat

A mechanically active heterotypic E-cadherin/N-cadherin adhesion enables fibroblasts to drive cancer cell invasion

scientific article published on 20 February 2017

Aberrant DNA methylation in non-small cell lung cancer-associated fibroblasts

scientific article published on 7 October 2015

Active Tensile Modulus of an Epithelial Monolayer

scientific article published on 11 December 2015

Active superelasticity in three-dimensional epithelia of controlled shape

scientific article published in Nature

Alveolar permeability and stretch: too far, too fast

scientific article published on 01 October 2008

Cell crawling mediates collective cell migration to close undamaged epithelial gaps

scientific article

Cell migration

scientific article published on 01 October 2012

Cell migration driven by cooperative substrate deformation patterns

scientific article published on 23 April 2010

Chase-and-run between adjacent cell populations promotes directional collective migration

scientific article

Collective cell durotaxis emerges from long-range intercellular force transmission

scientific article published on September 2016

Compressed sensing traction force microscopy.

scientific article published on 20 August 2015

Control of Mechanotransduction by Molecular Clutch Dynamics

scientific article published on 26 February 2018

Control of cell-cell forces and collective cell dynamics by the intercellular adhesome

scientific article

Curvature in Biological Systems: Its Quantification, Emergence, and Implications across the Scales

scientific article published in 2023

Cytoskeleton dynamics: fluctuations within the network.

scientific article published on 9 February 2007

Do biophysical properties of the airway smooth muscle in culture predict airway hyperresponsiveness?

scientific article published on 16 February 2006

Effective viscosity and dynamics of spreading epithelia: a solvable model.

scientific article published on 18 January 2017

Endocytic reawakening of motility in jammed epithelia

scientific article published on 30 January 2017

Epidermal growth factor receptor and integrins control force-dependent vinculin recruitment to E-cadherin junctions.

scientific article published on 27 February 2018

Epithelial bridges maintain tissue integrity during collective cell migration.

scientific article published on December 2013

Fast and slow dynamics of the cytoskeleton

scientific article published on 09 July 2006

Force Triggers YAP Nuclear Entry by Regulating Transport across Nuclear Pores

scientific article

Force loading explains spatial sensing of ligands by cells

scientific article published on 6 December 2017

Forces driving epithelial wound healing.

scientific article

Front-Rear Polarization by Mechanical Cues: From Single Cells to Tissues.

scientific article

Gap geometry dictates epithelial closure efficiency.

scientific article

Generation of stable orthogonal gradients of chemical concentration and substrate stiffness in a microfluidic device

scientific article

Geometry-driven migration efficiency of minimal cell clusters

preprint

Geometry-driven migration efficiency of minimal cell clusters

preprint dated 18 July 2022

Glass-like dynamics of collective cell migration.

scientific article

Gleevec, an Abl family inhibitor, produces a profound change in cell shape and migration

scientific article

Hydraulic Fracture and Toughening of a Brittle Layer Bonded to a Hydrogel

scientific article published on 28 October 2015

Hydraulic fracture during epithelial stretching.

scientific article

Hydraulic fracturing in cells and tissues: fracking meets cell biology

scientific article published on 6 December 2016

Increased migration of olfactory ensheathing cells secreting the Nogo receptor ectodomain over inhibitory substrates and lesioned spinal cord

scientific article

Intermediate filaments control collective migration by restricting traction forces and sustaining cell-cell contacts

scientific article published on 06 July 2018

Long-lived force patterns and deformation waves at repulsive epithelial boundaries

scientific article published on 11 September 2017

Long-term single-cell lineage tracing of deep structures using three-photon activation

Mapping forces and kinematics during collective cell migration.

scientific article published on 8 January 2015

Mapping the cytoskeletal prestress.

scientific article published on 17 February 2010

Mechanical guidance of cell migration: lessons from chemotaxis ⬇️

scientific article published on May 28, 2013

Mechanical regulation of a molecular clutch defines force transmission and transduction in response to matrix rigidity.

scientific article published on 11 April 2016

Mechanics of epithelial closure over non-adherent environments

scientific article

Mechanochemical feedback control of dynamin independent endocytosis modulates membrane tension in adherent cells

scientific article published in Nature Communications

Mechanosensing of substrate thickness.

scientific article published on 22 October 2010

Microrheology of human lung epithelial cells measured by atomic force microscopy

scientific article

Monitoring developmental force distributions in reconstituted embryonic epithelia

scientific article published on 02 September 2015

Monolayer stress microscopy: limitations, artifacts, and accuracy of recovered intercellular stresses

scientific article

Myelin-associated proteins block the migration of olfactory ensheathing cells: an in vitro study using single-cell tracking and traction force microscopy

scientific article

Non-equilibrium cytoquake dynamics in cytoskeletal remodeling and stabilization

scientific article published on 26 September 2016

Optogenetic control of cellular forces and mechanotransduction.

scientific article

Oscillatory magnetic tweezers based on ferromagnetic beads and simple coaxial coils

article by Xavier Trepat et al published September 2003 in Review of Scientific Instruments

Oscillometric assessment of airway obstruction in a mechanical model of vocal cord dysfunction

scientific article published in January 2004

P-cadherin promotes collective cell migration via a Cdc42-mediated increase in mechanical forces

scientific article

Physical forces during collective cell migration

Physical principles of membrane remodelling during cell mechanoadaptation

scientific article

Piezo2 channel regulates RhoA and actin cytoskeleton to promote cell mechanobiological responses.

scientific article published on 5 February 2018

Plithotaxis and emergent dynamics in collective cellular migration ⬇️

scientific article published on July 23, 2011

Propulsion and navigation within the advancing monolayer sheet.

scientific article published on 23 June 2013

Pulling it together in three dimensions

scientific article published on December 2010

Quantifying forces in cell biology.

scientific article

Regulation of cell cycle progression by cell-cell and cell-matrix forces

scientific article published on 25 May 2018

Reinforcement versus fluidization in cytoskeletal mechanoresponsiveness

scientific article (publication date: 2009)

Response of automatic continuous positive airway pressure devices to different sleep breathing patterns: a bench study

scientific article published in August 2002

Rigidity sensing and adaptation through regulation of integrin types.

scientific article

Seeds of Locally Aligned Motion and Stress Coordinate a Collective Cell Migration

scientific article

Sticking, steering, squeezing and shearing: cell movements driven by heterotypic mechanical forces

scientific article published on 30 April 2018

Substrate stiffening promotes endothelial monolayer disruption through enhanced physical forces

scientific article published on 22 September 2010

Supracellular contraction at the rear of neural crest cell groups drives collective chemotaxis

scientific article

TRPM7 controls mesenchymal features of breast cancer cells by tensional regulation of SOX4.

scientific article published on 20 April 2018

TRPV4 participates in the establishment of trailing adhesions and directional persistence of migrating cells

scientific article

The Role of Mitotic Cell-Substrate Adhesion Re-modeling in Animal Cell Division.

scientific article published in April 2018

The force loading rate drives cell mechanosensing through both reinforcement and cytoskeletal softening

scientific article published on 09 July 2021

The temperature dependence of cell mechanics measured by atomic force microscopy.

scientific article

Thrombin and histamine induce stiffening of alveolar epithelial cells

scientific article

Traction Forces of Endothelial Cells under Slow Shear Flow.

scientific article published on October 2015

Traction forces at the cytokinetic ring regulate cell division and polyploidy in the migrating zebrafish epicardium

scientific article published on 03 June 2019

Universal behavior of the osmotically compressed cell and its analogy to the colloidal glass transition

scholarly article

Universal physical responses to stretch in the living cell

scientific article published on May 2007

Viscoelasticity of human alveolar epithelial cells subjected to stretch.

scientific article

List of works by Xavier Trepat

A mechanically active heterotypic E-cadherin/N-cadherin adhesion enables fibroblasts to drive cancer cell invasion

Aberrant DNA methylation in non-small cell lung cancer-associated fibroblasts

Active Tensile Modulus of an Epithelial Monolayer

Active superelasticity in three-dimensional epithelia of controlled shape

Alveolar permeability and stretch: too far, too fast

Cell crawling mediates collective cell migration to close undamaged epithelial gaps

Cell migration

Cell migration driven by cooperative substrate deformation patterns

Chase-and-run between adjacent cell populations promotes directional collective migration

Collective cell durotaxis emerges from long-range intercellular force transmission

Compressed sensing traction force microscopy.

Control of Mechanotransduction by Molecular Clutch Dynamics

Control of cell-cell forces and collective cell dynamics by the intercellular adhesome

Curvature in Biological Systems: Its Quantification, Emergence, and Implications across the Scales

Cytoskeleton dynamics: fluctuations within the network.

Do biophysical properties of the airway smooth muscle in culture predict airway hyperresponsiveness?

Effective viscosity and dynamics of spreading epithelia: a solvable model.

Endocytic reawakening of motility in jammed epithelia

Epidermal growth factor receptor and integrins control force-dependent vinculin recruitment to E-cadherin junctions.

Epithelial bridges maintain tissue integrity during collective cell migration.

Fast and slow dynamics of the cytoskeleton

Force Triggers YAP Nuclear Entry by Regulating Transport across Nuclear Pores

Force loading explains spatial sensing of ligands by cells

Forces driving epithelial wound healing.

Front-Rear Polarization by Mechanical Cues: From Single Cells to Tissues.

Gap geometry dictates epithelial closure efficiency.

Generation of stable orthogonal gradients of chemical concentration and substrate stiffness in a microfluidic device

Geometry-driven migration efficiency of minimal cell clusters

Geometry-driven migration efficiency of minimal cell clusters

Glass-like dynamics of collective cell migration.

Gleevec, an Abl family inhibitor, produces a profound change in cell shape and migration

Hydraulic Fracture and Toughening of a Brittle Layer Bonded to a Hydrogel

Hydraulic fracture during epithelial stretching.

Hydraulic fracturing in cells and tissues: fracking meets cell biology

Increased migration of olfactory ensheathing cells secreting the Nogo receptor ectodomain over inhibitory substrates and lesioned spinal cord

Intermediate filaments control collective migration by restricting traction forces and sustaining cell-cell contacts

Long-lived force patterns and deformation waves at repulsive epithelial boundaries

Long-term single-cell lineage tracing of deep structures using three-photon activation

Mapping forces and kinematics during collective cell migration.

Mapping the cytoskeletal prestress.

Mechanical guidance of cell migration: lessons from chemotaxis ⬇️

Mechanical regulation of a molecular clutch defines force transmission and transduction in response to matrix rigidity.

Mechanics of epithelial closure over non-adherent environments

Mechanochemical feedback control of dynamin independent endocytosis modulates membrane tension in adherent cells

Mechanosensing of substrate thickness.

Microrheology of human lung epithelial cells measured by atomic force microscopy

Monitoring developmental force distributions in reconstituted embryonic epithelia

Monolayer stress microscopy: limitations, artifacts, and accuracy of recovered intercellular stresses

Myelin-associated proteins block the migration of olfactory ensheathing cells: an in vitro study using single-cell tracking and traction force microscopy

Non-equilibrium cytoquake dynamics in cytoskeletal remodeling and stabilization

Optogenetic control of cellular forces and mechanotransduction.

Oscillatory magnetic tweezers based on ferromagnetic beads and simple coaxial coils

Oscillometric assessment of airway obstruction in a mechanical model of vocal cord dysfunction

P-cadherin promotes collective cell migration via a Cdc42-mediated increase in mechanical forces

Physical forces during collective cell migration

Physical principles of membrane remodelling during cell mechanoadaptation

Piezo2 channel regulates RhoA and actin cytoskeleton to promote cell mechanobiological responses.

Plithotaxis and emergent dynamics in collective cellular migration ⬇️

Propulsion and navigation within the advancing monolayer sheet.

Pulling it together in three dimensions

Quantifying forces in cell biology.

Regulation of cell cycle progression by cell-cell and cell-matrix forces

Reinforcement versus fluidization in cytoskeletal mechanoresponsiveness

Response of automatic continuous positive airway pressure devices to different sleep breathing patterns: a bench study

Rigidity sensing and adaptation through regulation of integrin types.

Seeds of Locally Aligned Motion and Stress Coordinate a Collective Cell Migration

Sticking, steering, squeezing and shearing: cell movements driven by heterotypic mechanical forces

Substrate stiffening promotes endothelial monolayer disruption through enhanced physical forces

Supracellular contraction at the rear of neural crest cell groups drives collective chemotaxis

TRPM7 controls mesenchymal features of breast cancer cells by tensional regulation of SOX4.

TRPV4 participates in the establishment of trailing adhesions and directional persistence of migrating cells

The Role of Mitotic Cell-Substrate Adhesion Re-modeling in Animal Cell Division.

The force loading rate drives cell mechanosensing through both reinforcement and cytoskeletal softening

The temperature dependence of cell mechanics measured by atomic force microscopy.

Thrombin and histamine induce stiffening of alveolar epithelial cells

Traction Forces of Endothelial Cells under Slow Shear Flow.

Traction forces at the cytokinetic ring regulate cell division and polyploidy in the migrating zebrafish epicardium

Universal behavior of the osmotically compressed cell and its analogy to the colloidal glass transition

Universal physical responses to stretch in the living cell