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List of works by Stefanie Scheu

A fluorescence reporter model defines "Tip-DCs" as the cellular source of interferon β in murine listeriosis

scientific article

A lymphotoxin-IFN-beta axis essential for lymphocyte survival revealed during cytomegalovirus infection

scientific article published in June 2005

A mouse model-based screening platform for the identification of immune activating compounds such as natural products for novel cancer immunotherapies

scientific article published on 09 October 2019

Activation of the integrated stress response during T helper cell differentiation

scientific article published on 7 May 2006

Alemtuzumab treatment alters circulating innate immune cells in multiple sclerosis

scientific article published on 12 October 2016

Alterations of the Innate Immune System in Susceptibility and Resilience After Social Defeat Stress

scientific article published on 13 July 2018

Altered B Cell Homeostasis in Patients with Major Depressive Disorder and Normalization of CD5 Surface Expression on Regulatory B Cells in Treatment Responders

scientific article

B and T lymphocyte attenuator regulates T cell activation through interaction with herpesvirus entry mediator

scientific journal article

Both functional LTbeta receptor and TNF receptor 2 are required for the development of experimental cerebral malaria

scientific article

CC chemokine receptor 4 is required for experimental autoimmune encephalomyelitis by regulating GM-CSF and IL-23 production in dendritic cells.

scientific article published on 21 February 2012

CD169+ macrophages regulate PD-L1 expression via type I interferon and thereby prevent severe immunopathology after LCMV infection

scientific article

Cannabinoid Receptor 2 Modulates Maturation of Dendritic Cells and Their Capacity to Induce Hapten-Induced Contact Hypersensitivity

scientific article published on 11 January 2020

Cannabinoid Receptor 2 Modulates Susceptibility to Experimental Cerebral Malaria through a CCL17-dependent Mechanism

scientific article published on 29 July 2016

Chemokine CCL17 is expressed by dendritic cells in the CNS during experimental autoimmune encephalomyelitis and promotes pathogenesis of disease

scientific article published on 19 June 2017

Critical roles for LIGHT and its receptors in generating T cell-mediated immunity during Leishmania donovani infection

scientific article

Cutting Edge: IFN-β Expression in the Spleen Is Restricted to a Subpopulation of Plasmacytoid Dendritic Cells Exhibiting a Specific Immune Modulatory Transcriptome Signature.

scientific article published on 2 May 2016

Cutting Edge: The RIG-I Ligand 3pRNA Potently Improves CTL Cross-Priming and Facilitates Antiviral Vaccination.

scientific article published on 27 January 2016

Cutting edge: selective blockade of LIGHT-lymphotoxin beta receptor signaling protects mice from experimental cerebral malaria caused by Plasmodium berghei ANKA.

scientific article published in December 2008

Entry mechanisms of herpes simplex virus 1 into murine epidermis: involvement of nectin-1 and herpesvirus entry mediator as cellular receptors

scientific article published on 15 October 2014

Expression of lymphotoxin-alphabeta on antigen-specific T cells is required for DC function

scientific article published on 23 April 2007

Hepatic Rac1 GTPase contributes to liver-mediated basal immune homeostasis and LPS-induced endotoxemia

scientific article published on 20 June 2018

Herpesvirus entry mediator (TNFRSF14) regulates the persistence of T helper memory cell populations

scientific article

IFNβ secreted by microglia mediates clearance of myelin debris in CNS autoimmunity

scientific article

IRF4 and BATF are critical for CD8⁺ T-cell function following infection with LCMV.

scientific article

Identification of a novel Dlg2 isoform differentially expressed in IFNβ-producing plasmacytoid dendritic cells.

scientific article published on 12 March 2018

Immunotherapeutic targeting of LIGHT/LTβR/HVEM pathway fully recapitulates the reduced cytotoxic phenotype of LIGHT-deficient T cells

scientific article published on 11 January 2016

In Vivo Conditions Enable IFNAR-Independent Type I Interferon Production by Peritoneal CD11b+ Cells upon Thogoto Virus Infection

scientific article

Independent of plasmacytoid dendritic cell (pDC) infection, pDC triggered by virus-infected cells mount enhanced type I IFN responses of different composition as opposed to pDC stimulated with free virus

scientific article published on 28 July 2014

Interferon β-Mediated Protective Functions of Microglia in Central Nervous System Autoimmunity ⬇️

scientific article published on 07 January 2019

LIGHT (TNFSF14/CD258) is a decisive factor for recovery from experimental autoimmune encephalomyelitis

scientific article published on 29 May 2013

M27 expressed by cytomegalovirus counteracts effective type I interferon induction of myeloid cells but not of plasmacytoid dendritic cells

scientific article published on 17 September 2014

Mitochondria, Microglia, and the Immune System-How Are They Linked in Affective Disorders?

scientific article published on 01 January 2018

Pro-apoptotic and immunostimulatory tetrahydroxanthone dimers from the endophytic fungus Phomopsis longicolla.

scientific article published on 11 December 2013

Production of IFNβ by Conventional Dendritic Cells after Stimulation with Viral Compounds and IFNβ-Independent IFNAR1-Signaling Pathways are Associated with Aggravation of Polymicrobial Sepsis

scientific article published on 07 September 2019

Reduced locomotor activity and exploratory behavior in CC chemokine receptor 4 deficient mice

scientific article published on 25 July 2016

Reduced type I interferon production by dendritic cells and weakened antiviral immunity in patients with Wiskott-Aldrich syndrome protein deficiency

scientific article

Reply to Othy et al.: Dendritic cell-specific expression of CCR4 is required for development of EAE.

scholarly article

Social Defeat Modulates T Helper Cell Percentages in Stress Susceptible and Resilient Mice

scientific article published on 17 July 2019

Sources of Type I Interferons in Infectious Immunity: Plasmacytoid Dendritic Cells Not Always in the Driver's Seat

scientific article published on 12 April 2019

Spatiotemporally restricted arenavirus replication induces immune surveillance and type I interferon-dependent tumour regression

scientific article published on March 2017

Sphingosine 1-Phosphate- and C-C Chemokine Receptor 2-Dependent Activation of CD4+ Plasmacytoid Dendritic Cells in the Bone Marrow Contributes to Signs of Sepsis-Induced Immunosuppression

scientific article published on 23 November 2017

Stochastic expression of the interferon-β gene

scientific article

Targeted disruption of LIGHT causes defects in costimulatory T cell activation and reveals cooperation with lymphotoxin beta in mesenteric lymph node genesis

scientific article

Th2 cells: orchestrating barrier immunity

scientific article published on January 2004

The C-C Chemokines CCL17 and CCL22 and Their Receptor CCR4 in CNS Autoimmunity

scientific article published on 2 November 2017

The TGF-β signaling modulators TRAP1/TGFBRAP1 and VPS39/Vam6/TLP are essential for early embryonic development.

scientific article

The cannabinoid receptor 2 is involved in acute rejection of cardiac allografts

scientific article published on 02 March 2015

The catalytic PI3K isoforms p110gamma and p110delta contribute to B cell development and maintenance, transformation, and proliferation

scientific article published on 3 March 2010

The lymphotoxin beta receptor is critically involved in controlling infections with the intracellular pathogens Mycobacterium tuberculosis and Listeria monocytogenes

scientific article published in May 2003

The tumor necrosis factor family member LIGHT is a target for asthmatic airway remodeling

scientific article

Therapeutic blockade of LIGHT interaction with herpesvirus entry mediator and lymphotoxin β receptor attenuates in vivo cytotoxic allogeneic responses

scientific article published on December 2014

Thymic medullary epithelial cell differentiation, thymocyte emigration, and the control of autoimmunity require lympho-epithelial cross talk via LTbetaR.

scientific article

Tissue macrophages suppress viral replication and prevent severe immunopathology in an interferon-I-dependent manner in mice

Transcription factor E2-2 is an essential and specific regulator of plasmacytoid dendritic cell development

scientific article

Tumor Necrosis Factor-Mediated Survival of CD169+ Cells Promotes Immune Activation during Vesicular Stomatitis Virus Infection

scientific article published on 15 November 2017

Visualization of IFNbeta production by plasmacytoid versus conventional dendritic cells under specific stimulation conditions in vivo

scholarly article

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