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List of works by Michael A Farrar

A developmentally controlled competitive STAT5-PU.1 DNA binding mechanism regulates activity of the Ig κ E3' enhancer.

scientific article published on 25 January 2012

Activation of the Raf-1 kinase cascade by coumermycin-induced dimerization.

scientific article

Adaptive Immunity to Leukemia Is Inhibited by Cross-Reactive Induced Regulatory T Cells

scientific article

Attenuation of IL-7 receptor signaling is not required for allelic exclusion

scientific article published on 01 March 2006

B cell receptor basal signaling regulates antigen-induced Ig light chain rearrangements

scientific article

B-1a cells acquire their unique characteristics by bypassing the pre-BCR selection stage

B-1a cells acquire their unique characteristics by bypassing the pre-BCR selection stage

scientific article published on 18 October 2019

BLNK suppresses pre-B-cell leukemogenesis through inhibition of JAK3.

scientific article published on December 2008

Combination therapeutics of Nilotinib and radiation in acute lymphoblastic leukemia as an effective method against drug-resistance

scientific article

Constitutive activation of STAT5 supersedes the requirement for cytokine and TCR engagement of CD4+ T cells in steady-state homeostasis

scientific article

Constitutively active STAT5 constructs

scientific article published on 01 January 2013

Control of B cell development by Ras-mediated activation of Raf.

scientific article

Costimulation via the tumor-necrosis factor receptor superfamily couples TCR signal strength to the thymic differentiation of regulatory T cells.

scientific article published on 16 March 2014

Coumermycin-induced dimerization of GyrB-containing fusion proteins.

scientific article

Cutting edge: CD28 and c-Rel-dependent pathways initiate regulatory T cell development.

scientific article

Cutting edge: IL-2 signals determine the degree of TCR signaling necessary to support regulatory T cell proliferation in vivo

scientific article

Design and Use of Constitutively Active STAT5 Constructs

scientific article published on 01 January 2010

Distinct effects of STAT5 activation on CD4+ and CD8+ T cell homeostasis: development of CD4+CD25+ regulatory T cells versus CD8+ memory T cells.

scientific article published in December 2003

Ebf1 or Pax5 haploinsufficiency synergizes with STAT5 activation to initiate acute lymphoblastic leukemia

scientific article

Evidence for heterogeneity of the DPA and DPB alleles derived from a DRw11,DQw7,DPw4 cell line

scientific article published in September 1989

Foxp3(+) regulatory T cell expansion required for sustaining pregnancy compromises host defense against prenatal bacterial pathogens

scientific article

Heterologous Vaccination and Checkpoint Blockade Synergize To Induce Antileukemia Immunity.

scientific article published on 25 April 2016

IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells

scientific article published in January 2007

IL-2, -7, and -15, but not thymic stromal lymphopoeitin, redundantly govern CD4+Foxp3+ regulatory T cell development

scientific article published on September 2008

IL-7 functionally segregates the pro-B cell stage by regulating transcription of recombination mediators across cell cycle

scientific article published on 11 May 2012

IL-7/STAT5 cytokine signaling pathway is essential but insufficient for maintenance of naive CD4 T cell survival in peripheral lymphoid organs

scientific article published on 01 January 2007

Identification of Cellular Sources of IL-2 Needed for Regulatory T Cell Development and Homeostasis

scientific article published on 04 May 2018

Identification of a functionally important sequence in the C terminus of the interferon-gamma receptor.

scientific article published on December 1992

Identification of two regions within the cytoplasmic domain of the human interferon-gamma receptor required for function.

scientific article published on October 1991

Immune tolerance. Group 3 innate lymphoid cells mediate intestinal selection of commensal bacteria-specific CD4⁺ T cells

scientific article published on 23 April 2015

In vivo survival and homeostatic proliferation of natural killer cells.

scientific article

Inhibition of cellular responsiveness to interferon-gamma (IFN gamma) induced by overexpression of inactive forms of the IFN gamma receptor.

scientific article published on May 1993

Interleukin-2 and STAT5 in regulatory T cell development and function

scientific article

Interleukin-7 is required for CD4(+) T cell activation and autoimmune neuroinflammation.

scientific article

JAK/STAT inhibition in macrophages promotes therapeutic resistance by inducing expression of protumorigenic factors

scientific article published on 30 May 2019

Linked T cell receptor and cytokine signaling govern the development of the regulatory T cell repertoire.

scientific article published on January 2008

Lymphoid precursors are directed to produce dendritic cells as a result of TLR9 ligation during herpes infection

scientific article published on 13 June 2008

Membrane localization of Raf assists engagement of downstream effectors

scientific article published on October 2000

Membrane localization, oligomerization, and phosphorylation are required for optimal raf activation

scientific article published on 6 October 2003

Pax5 loss imposes a reversible differentiation block in B-progenitor acute lymphoblastic leukemia

scientific article

RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci

scientific journal article

Regulation of lymphocyte development by cell-type-specific interpretation of Notch signals.

scientific article published on 14 January 2008

Regulatory T Cell Development in the Thymus

scientific article published on 01 October 2019

Restricted STAT5 activation dictates appropriate thymic B versus T cell lineage commitment

scientific article published in June 2005

STAT5 activation underlies IL7 receptor-dependent B cell development

scientific article published in April 2004

Signal transduction pathways regulating the development of alpha beta T cells

scientific article published in June 1998

Sleeping Beauty Screen Identifies RREB1 and Other Genetic Drivers in Human B-cell Lymphoma

scientific article published on 24 October 2018

Sleeping Beauty transposon screen identifies signaling modules that cooperate with STAT5 activation to induce B-cell acute lymphoblastic leukemia

scientific article published on 26 October 2015

The lineage stability and suppressive program of regulatory T cells require protein O-GlcNAcylation

scientific article published in Nature Communications

The role of STAT5 in the development, function, and transformation of B and T lymphocytes.

scientific article published on January 2011

Thymic regulatory T cells arise via two distinct developmental programs

scientific article published on 14 January 2019

Tonic BCR signaling represses receptor editing via Raf- and calcium-dependent signaling pathways

scientific article published on 7 October 2010

Turning transcription on or off with STAT5: when more is less

scientific article published on 16 November 2011

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