List of works - Jonathan Sperry

(1R,1'R,3S,3'S)-5,5',10,10'-Tetra-meth-oxy-1,1',3,3'-tetra-methyl-3,3',4,4'-tetra-hydro-1H,1'H-8,8'-bi[benzo[g]isochromene].

scientific article published on 29 March 2008

4,4'-Bismoschamine: biomimetic synthesis and evidence to support structural equivalency to montamine

scientific article published in September 2016

A Bidirectional Synthesis of (+)-Terreusinone

scientific article published on 29 June 2012

A Complementary Synthetic Approach to Fluorazone

scientific article published on 22 October 2013

A Facile Cross-Metathesis-Radical-Cyclisation Approach to Monobenzannulated Spiroketals

scientific article published on 24 February 2009

A Facile Enantioselective Synthesis of the Dimeric Pyranonaphthoquinone Core of the Cardinalins

scientific article published in April 2008

A Procedure for Transforming Indoles into Indolequinones

scientific article published on 6 January 2015

A biomimetic synthesis of calothrixin B

A concise synthesis of meridianin F

scientific article published in August 2011

A furoindoline synthesis by remote radical functionalization

scientific article published in October 2012

A novel dihydrodifuropyridine scaffold derived from ketones and the chitin-derived heterocycle 3-acetamido-5-acetylfuran

scientific article published on 6 December 2017

A short synthesis of the endogenous plant metabolite 7-hydroxyoxindole-3-acetic acid (7-OH-OxIAA) using simultaneous C–H borylations

scientific article published in October 2014

A simple solid phase, peptide-based fluorescent assay for the efficient and universal screening of HRV 3C protease inhibitors

scientific article published in August 2012

Acetyl-CoA-mediated activation of Mycobacterium tuberculosis isocitrate lyase 2

scientific article published on 11 October 2019

Alkaloids from the Traditional Chinese Medicine ChanSu: synthesis-enabled structural reassignment of bufopyramide to bufoserotonin C.

scientific article published on 24 June 2015

An Efficient Enantioselective Synthesis of the 3C Protease Inhibitor (-)-Thysanone

scientific article published on 2 July 2008

An approach to an enantioselective synthesis of crisamicin A via a novel double Hauser–Kraus annulation strategy

scientific article published in April 2008

Bio-Based Chiral Amines via Aza-Michael Additions to (-)-Levoglucosenone Under Aqueous Conditions

scientific article published on 7 May 2018

Bioinspired Total Synthesis and Stereochemical Revision of the Fungal Metabolite Pestalospirane B.

scientific article published on 16 June 2017

Bioinspired total synthesis and structural revision of yuremamine, an alkaloid from the entheogenic plant Mimosa tenuiflora

scientific article published in 2015

Biomimetic Synthesis of 2,5-Bis(indol-3-ylmethyl)pyrazine via Intermolecular Amino Aldehyde Cyclization

scientific article published on 13 September 2011

Biomimetic Synthesis of Dendridine A

scientific article published on 20 February 2015

Biomimetic Synthesis of Phenazine-1,6-dicarboxylic Acid (PDC)

scientific article published on 9 November 2012

Biomimetic approaches to diazonamide A. Direct synthesis of the indole bis-oxazole fragment by oxidation of a TyrValTrpTrp tetrapeptide

scientific article published on 09 May 2006

Biomimetic studies towards the cardinalins: synthesis of (+)-ventiloquinone L and an unusual dimerisation.

scientific article

Biomimetic synthesis of nudicaulins I and II, yellow pigments from the Iceland poppy Papaver nudicaule

scientific article published on 01 November 2019

Biomimetic synthesis of the bisindole framework present in sciodole, an alkaloid from Tricholoma sciodes

scientific article published in 2018

Chemoenzymatic synthesis of deoxy analogues of the DNA topoisomerase II inhibitor eleutherin and the 3C-protease inhibitor thysanone

scientific article published in May 2008

Clean Synthesis of 5-Hydroxymethylfurfural and Levulinic Acid by Aqueous Phase Conversion of Levoglucosenone over Solid Acid Catalysts

scientific article published on 13 February 2019

Cleavage of lignin model compounds and ligninox using aqueous oxalic acid

scientific article published on 01 August 2019

Concise syntheses of 5,6-dibromotryptamine and 5,6-dibromo-N,N-dimethyltryptamine en route to the antibiotic alternatamide D

scientific article published in August 2011

Development of NMR and thermal shift assays for the evaluation of isocitrate lyase inhibitors

scientific article published in November 2017

Diazonamide studies. A direct synthesis of the indole bis-oxazole fragment from tri- and tetra-peptides using biomimetic oxidative cyclizations

Discovery of a 1,2-bis(3-indolyl)ethane that selectively inhibits the pyruvate kinase of methicillin-resistant Staphylococcus aureus over human isoforms

scientific article published on 16 September 2014

Efficient Synthesis of the Spiroacetal Core of Paecilospirone via Oxidative Radical Cyclisation

scientific article published on 13 May 2011

Enantioselective Synthesis of an Analogue of Nanaomycin A

scientific article published in September 2007

Enantioselective Synthesis of the 3C-Protease Inhibitor (-)-Thysanone by a Staunton-Weinreb Annulation Strategy

scientific article published on 8 June 2009

Enantioselective synthesis of pyranonaphthoquinone antibiotics using a CBS reduction/cross-metathesis/oxa-Michael strategy

scientific article published in 2011

Enantioselective synthesis of the dimeric pyranonaphthoquinone core of the cardinalins using a late-stage homocoupling strategy

scientific article published on 10 October 2008

Extending the Utility of the Bartoli Indolization: Synthesis of Marinoquinolines C and E

scientific article published on 23 January 2013

Flavoalkaloids-Isolation, Biological Activity, and Total Synthesis

scientific article published in June 2016

Flexible synthesis of diverse N-heterocycles from substrates attainable from biomass

scientific article published in 2016

Formal synthesis of nanaomycin D via a Hauser–Kraus annulation using a chiral enone-lactone

scientific article published in September 2015

Heteroatom-directed reverse Wacker oxidations. Synthesis of the reported structure of (-)-herbaric acid

scientific article published on November 2010

Heterocycle construction using the biomass-derived building block itaconic acid

Improved Synthesis of the Benzyne Precursor 2-(Trimethylsilyl)phenyl Trifluoromethanesulfonate

scientific article published on 4 January 2010

Iridium-Catalysed C–H Borylation Facilitates a Total Synthesis of the HRV 3C Protease Inhibitor (±)-Thysanone

scientific article published on 10 January 2014

Iridium-Catalyzed C–H Borylation-Based Synthesis of Natural Indolequinones

scientific article published on 6 March 2012

Iridium-Catalyzed Triborylation of 3-Substituted Indoles

scientific article published in 2015

Isolation, biological activity and synthesis of benzannulated spiroketal natural products

scientific article published on 04 March 2010

Mushroom-Derived Indole Alkaloids

scientific article published on 19 July 2017

Natural Product-Inspired Pyranonaphthoquinone Inhibitors of Indoleamine 2,3-Dioxygenase-1 (IDO-1)

scientific article published in 2013

Natural Products with Heteroatom-Rich Ring Systems

scientific article published on 14 November 2017

Natural products containing a nitrogen-nitrogen bond

scientific article published on 11 April 2013

Natural products targeting telomere maintenance

scientific article published in 2011

Non-monoterpenoid azepinoindole alkaloids

scientific article published in 2018

One-pot oxidative hydrolysis-oxidative cleavage of 7-borylindoles enables access to o-amidophenols and 4-acylbenzoxazoles

scientific article published on 27 February 2020

Oxidative Ring-Expansion of a Chitin-Derived Platform Enables Access to Unexplored 2-Amino Sugar Chemical Space

scientific article published on 7 January 2019

Palladium-Catalyzed Heteroannulation Approach to 1,2-Bis(3-indolyl)ethanes

scientific article published on 12 August 2013

Photosensitized Cross-Linking of Tryptophan and Tyrosine Derivatives by Rose Bengal in Aqueous Solutions

scientific article published on 7 August 2018

Production of Levoglucosenone and Dihydrolevoglucosenone by Catalytic Reforming of Volatiles from Cellulose Pyrolysis Using Supported Ionic Liquid Phase

scientific article published on 21 December 2016

Pyranonaphthoquinone derivatives of eleutherin, ventiloquinone L, thysanone and nanaomycin A possessing a diverse topoisomerase II inhibition and cytotoxicity spectrum

scientific article published on 4 September 2009

Pyranonaphthoquinones--isolation, biological activity and synthesis

scientific article published on 29 October 2007

Pyrazine alkaloids via dimerization of amino acid-derived α-amino aldehydes: biomimetic synthesis of 2,5-diisopropylpyrazine, 2,5-bis(3-indolylmethyl)pyrazine and actinopolymorphol C

scientific article published in 2012

Role of the <i>In Situ</i> Generated Acidic Protons and Cl Species for 2,5-Hexanedione Production from the New Platform Molecule 5-(Chloromethyl)furfural

scientific article published in 2023

Schischkiniin support studies: synthetic access to 1,1'-bisindoles

scientific article

Structural Revision of Pseudocerosine and Validation of a Biosynthetic Proposal for E-ring Formation in Pyridoacridine Alkaloids

scientific article published on 13 April 2020

Studies towards the synthesis of montamine: synthesis of the 1,2-bis(indolyl)ethylhydrazine fragment

scientific article published in April 2013

Synthesis and Biological Evaluation of 7-Deoxy Analogues of the Human Rhinovirus 3C Protease Inhibitor Thysanone

scientific article published on 7 November 2013

Synthesis and cytotoxicity of pyranonaphthoquinone natural product analogues under bioreductive conditions.

scientific article published in December 2013

Synthesis and electrochemical detection of a thiazolyl-indole natural product isolated from the nosocomial pathogen Pseudomonas aeruginosa.

scientific article published on 29 July 2016

Synthesis and evaluation of 9-deoxy analogues of (-)-thysanone, an inhibitor of HRV 3C protease

scientific article published on 22 September 2014

Synthesis of 2-(3′-Indolyl)tetrahydrofurans by Oxidative Cycloetherification

scientific article published on 23 February 2015

Synthesis of Alocasin A.

scientific article published on December 2015

Synthesis of Benzannulated Spiroketals Using an Oxidative Radical Cyclization

scientific article published on 4 April 2011

Synthesis of Benzotriazole Analogues of the Helicobactericidal Agents CJ-13,015, CJ-13,102, CJ-13,108, and CJ-13,104 Using a Regioselective 1,3-Dipolar Cycloaddition

scientific article published on 7 December 2010

Synthesis of Inducamides A and B.

scientific article published on 23 December 2015

Synthesis of a C8 oxygenated pyranonaphthoquinone: a useful precursor to dimeric pyranonaphthoquinones

scientific article published in April 2008

Synthesis of colletotrichumine A

scientific article published in January 2015

Synthesis of natural products containing spiroketals via intramolecular hydrogen abstraction

scientific article published on 7 October 2009

Synthesis of putative clausenal from carbazole using sequential C–H borylations

scientific article published in April 2017

Synthesis of scalaridine A

scientific article published in October 2015

Synthesis of the 1,2,4-Thiadiazole Alkaloid Polyaurine B

scientific article published on 16 April 2020

Synthesis of the 1,2,4-thiadiazole alkaloids polycarpathiamines A and B

scientific article published in 2016

Synthesis of the 2-methylene analogue of the HRV 3C protease inhibitor thysanone (2-carbathysanone)

scientific article published in February 2014

Synthesis of the Pyranonaphthoquinones Dehydroherbarin, (+)-Astropaquinone B and (+)-Astropaquinone C en Route to Ascomycones A and B

scientific article published on 18 June 2010

Synthesis of the Selective Neuronal Nitric Oxide Synthase (nNOS) Inhibitor 5,6-Dibromo-2′-demethylaplysinopsin

scientific article published on 15 March 2011

Synthesis of the Tetracyclic Core of Berkelic Acid Using Gold(I)-Catalyzed Hydroarylation and Oxidative Radical Cyclizations

scientific article published on 27 November 2012

Synthesis of the Tetracyclic Cores of the Integrastatins, Epicoccolide A and Epicocconigrone A

scientific article published on 28 August 2019

Synthesis of the calothrixins, pentacyclic indolo[3,2-j]phenanthridine alkaloids, using a biomimetic approach

Synthesis of triazole analogues of the nanaomycin antibiotics using ‘click chemistry’

scientific article published in June 2010

Synthetic Access to 3,5,7-Trisubstituted Indoles Enabled by Iridium-Catalyzed C–H Borylation

scientific article published on 8 May 2017

Synthetic Studies toward Bisindigotin: Polyheteroaromatic Scaffolds via Skeletal Rearrangements of a Diacetoxytetraindole

scientific article published on 09 December 2020

Synthetic studies toward inducamide C

scientific article published on 14 December 2020

Synthetic studies towards dendridine A: synthesis of hemi-dendridine A acetate by Fischer indolization

scientific article published in July 2012

Synthetic studies towards putative yuremamine using an iterative C(sp(3))-H arylation strategy

scientific article published on 18 February 2016

Targeting isocitrate lyase for the treatment of latent tuberculosis.

scientific article published on 27 April 2017

Telomerase Inhibition Studies of Novel Spiroketal-Containing Rubromycin Derivatives

scientific article published in 2013

The Oxidation of Amides to Imides: A Powerful Synthetic Transformation

article

The curious yellow colouring matter of the Iceland poppy

scientific article published on 08 July 2020

The influence of microwave irradiation on lipase-catalyzed kinetic resolution of racemic secondary alcohols

scientific article published in July 2007

Total Synthesis and Absolute Configuration of (−)-Berkeleyamide A

scientific article published on 5 February 2010

Total Synthesis of Danshenspiroketallactone

scientific article published on 28 November 2011

Total Synthesis of an Isatis indigotica-Derived Alkaloid Using a Biomimetic Thio-Diels-Alder Reaction.

scientific article published on 30 May 2018

Total Synthesis of the Initially Reported and Revised Structures of the Neuroprotective Agent Palmyrolide A

scientific article published on 9 October 2012

Total Synthesis of the Photoprotecting Dipyrrolobenzoquinone (+)-Terreusinone

scientific article published on 16 December 2011

Total syntheses of (±)-spiroindimicins B and C enabled by a late-stage Schöllkopf-Magnus-Barton-Zard (SMBZ) reaction

scientific article published on 16 November 2015

Total syntheses of the dipyrrolobenzoquinone (+)-terreusinone enabled by an evaluation of 4-methylpent-1-yn-3-ols in the Larock indole synthesis

scientific article published in June 2013

Total synthesis of (-)-aspergilazine A.

scientific article published on 23 September 2014

Total synthesis of putative montamine and a proposed structural reassignment

scientific article published in 2014

Toward an Asymmetric Synthesis of the Dimeric Pyranonaphthoquinone Antibiotic Crisamicin A

scientific article published on 23 July 2014

Towards a biomimetic synthesis of schischkiniin: assembling the bis-dihydropyrazinone cycloaddition precursor

scientific article published in May 2014

Towards the Shell Biorefinery: Sustainable Synthesis of the Anticancer Alkaloid Proximicin A from Chitin

scientific article

List of works by Jonathan Sperry

(1R,1'R,3S,3'S)-5,5',10,10'-Tetra-meth-oxy-1,1',3,3'-tetra-methyl-3,3',4,4'-tetra-hydro-1H,1'H-8,8'-bi[benzo[g]isochromene].

4,4'-Bismoschamine: biomimetic synthesis and evidence to support structural equivalency to montamine

A Bidirectional Synthesis of (+)-Terreusinone

A Complementary Synthetic Approach to Fluorazone

A Facile Cross-Metathesis-Radical-Cyclisation Approach to Monobenzannulated Spiroketals

A Facile Enantioselective Synthesis of the Dimeric Pyranonaphthoquinone Core of the Cardinalins

A Procedure for Transforming Indoles into Indolequinones

A biomimetic synthesis of calothrixin B

A concise synthesis of meridianin F

A furoindoline synthesis by remote radical functionalization

A novel dihydrodifuropyridine scaffold derived from ketones and the chitin-derived heterocycle 3-acetamido-5-acetylfuran

A short synthesis of the endogenous plant metabolite 7-hydroxyoxindole-3-acetic acid (7-OH-OxIAA) using simultaneous C–H borylations

A simple solid phase, peptide-based fluorescent assay for the efficient and universal screening of HRV 3C protease inhibitors

Acetyl-CoA-mediated activation of Mycobacterium tuberculosis isocitrate lyase 2

Alkaloids from the Traditional Chinese Medicine ChanSu: synthesis-enabled structural reassignment of bufopyramide to bufoserotonin C.

An Efficient Enantioselective Synthesis of the 3C Protease Inhibitor (-)-Thysanone

An approach to an enantioselective synthesis of crisamicin A via a novel double Hauser–Kraus annulation strategy

Bio-Based Chiral Amines via Aza-Michael Additions to (-)-Levoglucosenone Under Aqueous Conditions

Bioinspired Total Synthesis and Stereochemical Revision of the Fungal Metabolite Pestalospirane B.

Bioinspired total synthesis and structural revision of yuremamine, an alkaloid from the entheogenic plant Mimosa tenuiflora

Biomimetic Synthesis of 2,5-Bis(indol-3-ylmethyl)pyrazine via Intermolecular Amino Aldehyde Cyclization

Biomimetic Synthesis of Dendridine A

Biomimetic Synthesis of Phenazine-1,6-dicarboxylic Acid (PDC)

Biomimetic approaches to diazonamide A. Direct synthesis of the indole bis-oxazole fragment by oxidation of a TyrValTrpTrp tetrapeptide

Biomimetic studies towards the cardinalins: synthesis of (+)-ventiloquinone L and an unusual dimerisation.

Biomimetic synthesis of nudicaulins I and II, yellow pigments from the Iceland poppy Papaver nudicaule

Biomimetic synthesis of the bisindole framework present in sciodole, an alkaloid from Tricholoma sciodes

Chemoenzymatic synthesis of deoxy analogues of the DNA topoisomerase II inhibitor eleutherin and the 3C-protease inhibitor thysanone

Clean Synthesis of 5-Hydroxymethylfurfural and Levulinic Acid by Aqueous Phase Conversion of Levoglucosenone over Solid Acid Catalysts

Cleavage of lignin model compounds and ligninox using aqueous oxalic acid

Concise syntheses of 5,6-dibromotryptamine and 5,6-dibromo-N,N-dimethyltryptamine en route to the antibiotic alternatamide D

Development of NMR and thermal shift assays for the evaluation of isocitrate lyase inhibitors

Diazonamide studies. A direct synthesis of the indole bis-oxazole fragment from tri- and tetra-peptides using biomimetic oxidative cyclizations

Discovery of a 1,2-bis(3-indolyl)ethane that selectively inhibits the pyruvate kinase of methicillin-resistant Staphylococcus aureus over human isoforms

Efficient Synthesis of the Spiroacetal Core of Paecilospirone via Oxidative Radical Cyclisation

Enantioselective Synthesis of an Analogue of Nanaomycin A

Enantioselective Synthesis of the 3C-Protease Inhibitor (-)-Thysanone by a Staunton-Weinreb Annulation Strategy

Enantioselective synthesis of pyranonaphthoquinone antibiotics using a CBS reduction/cross-metathesis/oxa-Michael strategy

Enantioselective synthesis of the dimeric pyranonaphthoquinone core of the cardinalins using a late-stage homocoupling strategy

Extending the Utility of the Bartoli Indolization: Synthesis of Marinoquinolines C and E

Flavoalkaloids-Isolation, Biological Activity, and Total Synthesis

Flexible synthesis of diverse N-heterocycles from substrates attainable from biomass

Formal synthesis of nanaomycin D via a Hauser–Kraus annulation using a chiral enone-lactone

Heteroatom-directed reverse Wacker oxidations. Synthesis of the reported structure of (-)-herbaric acid

Heterocycle construction using the biomass-derived building block itaconic acid

Improved Synthesis of the Benzyne Precursor 2-(Trimethylsilyl)phenyl Trifluoromethanesulfonate

Iridium-Catalysed C–H Borylation Facilitates a Total Synthesis of the HRV 3C Protease Inhibitor (±)-Thysanone

Iridium-Catalyzed C–H Borylation-Based Synthesis of Natural Indolequinones

Iridium-Catalyzed Triborylation of 3-Substituted Indoles

Isolation, biological activity and synthesis of benzannulated spiroketal natural products

Mushroom-Derived Indole Alkaloids

Natural Product-Inspired Pyranonaphthoquinone Inhibitors of Indoleamine 2,3-Dioxygenase-1 (IDO-1)

Natural Products with Heteroatom-Rich Ring Systems

Natural products containing a nitrogen-nitrogen bond

Natural products targeting telomere maintenance

Non-monoterpenoid azepinoindole alkaloids

One-pot oxidative hydrolysis-oxidative cleavage of 7-borylindoles enables access to o-amidophenols and 4-acylbenzoxazoles

Oxidative Ring-Expansion of a Chitin-Derived Platform Enables Access to Unexplored 2-Amino Sugar Chemical Space

Palladium-Catalyzed Heteroannulation Approach to 1,2-Bis(3-indolyl)ethanes

Photosensitized Cross-Linking of Tryptophan and Tyrosine Derivatives by Rose Bengal in Aqueous Solutions

Production of Levoglucosenone and Dihydrolevoglucosenone by Catalytic Reforming of Volatiles from Cellulose Pyrolysis Using Supported Ionic Liquid Phase

Pyranonaphthoquinone derivatives of eleutherin, ventiloquinone L, thysanone and nanaomycin A possessing a diverse topoisomerase II inhibition and cytotoxicity spectrum

Pyranonaphthoquinones--isolation, biological activity and synthesis

Pyrazine alkaloids via dimerization of amino acid-derived α-amino aldehydes: biomimetic synthesis of 2,5-diisopropylpyrazine, 2,5-bis(3-indolylmethyl)pyrazine and actinopolymorphol C

Role of the <i>In Situ</i> Generated Acidic Protons and Cl Species for 2,5-Hexanedione Production from the New Platform Molecule 5-(Chloromethyl)furfural

Schischkiniin support studies: synthetic access to 1,1'-bisindoles

Structural Revision of Pseudocerosine and Validation of a Biosynthetic Proposal for E-ring Formation in Pyridoacridine Alkaloids

Studies towards the synthesis of montamine: synthesis of the 1,2-bis(indolyl)ethylhydrazine fragment

Synthesis and Biological Evaluation of 7-Deoxy Analogues of the Human Rhinovirus 3C Protease Inhibitor Thysanone

Synthesis and cytotoxicity of pyranonaphthoquinone natural product analogues under bioreductive conditions.

Synthesis and electrochemical detection of a thiazolyl-indole natural product isolated from the nosocomial pathogen Pseudomonas aeruginosa.

Synthesis and evaluation of 9-deoxy analogues of (-)-thysanone, an inhibitor of HRV 3C protease

Synthesis of 2-(3′-Indolyl)tetrahydrofurans by Oxidative Cycloetherification

Synthesis of Alocasin A.

Synthesis of Benzannulated Spiroketals Using an Oxidative Radical Cyclization

Synthesis of Benzotriazole Analogues of the Helicobactericidal Agents CJ-13,015, CJ-13,102, CJ-13,108, and CJ-13,104 Using a Regioselective 1,3-Dipolar Cycloaddition

Synthesis of Inducamides A and B.

Synthesis of a C8 oxygenated pyranonaphthoquinone: a useful precursor to dimeric pyranonaphthoquinones

Synthesis of colletotrichumine A