List of works by Veerle Janssens

B56δ-related protein phosphatase 2A dysfunction identified in patients with intellectual disability.

scientific article

Cacnb4 directly couples electrical activity to gene expression, a process defective in juvenile epilepsy

scientific journal article

Clinical, neuroimaging and molecular characteristics of <i>PPP2R5D</i>-related neurodevelopmental disorders: an expanded series with functional characterisation and genotype–phenotype analysis

scientific article published in 2022

Combination of Hypoglycemia and Metformin Impairs Tumor Metabolic Plasticity and Growth by Modulating the PP2A-GSK3β-MCL-1 Axis

scientific article published on 25 April 2019

De Novo Mutations Affecting the Catalytic Cα Subunit of PP2A, PPP2CA, Cause Syndromic Intellectual Disability Resembling Other PP2A-Related Neurodevelopmental Disorders

scientific article published on 27 December 2018

Dephosphorylation of the HIV-1 restriction factor SAMHD1 is mediated by PP2A-B55α holoenzymes during mitotic exit.

scientific article published on 8 June 2018

Fructose-1,6-bisphosphate couples glycolytic flux to activation of Ras.

scientific article published on 13 October 2017

Functional analysis of conserved domains in the phosphotyrosyl phosphatase activator. Molecular cloning of the homologues from Drosophila melanogaster and Saccharomyces cerevisiae

scientific article published in September 1998

Functional analysis of the promoter region of the human phosphotyrosine phosphatase activator gene: Yin Yang 1 is essential for core promoter activity

article

Genomic organisation, chromosomal localisation tissue distribution and developmental regulation of the PR61/B' regulatory subunits of protein phosphatase 2A in mice

scientific article published on February 2004

Glucose-induced posttranslational activation of protein phosphatases PP2A and PP1 in yeast

scientific article published on 31 January 2012

Identification and characterization of B''-subunits of protein phosphatase 2 A in Xenopus laevis oocytes and adult tissues. Evidence for an independent N-terminal splice variant of PR130 and an extended human PR48 protein

article

Identification and functional analysis of two Ca2+-binding EF-hand motifs in the B"/PR72 subunit of protein phosphatase 2A.

scientific article published on 10 January 2003

In vivo pieces of the PP2A onco-puzzle fallen into place

scientific article published in November 2017

Inhibition of the Wnt signaling pathway by the PR61 subunit of protein phosphatase 2A

scientific article (publication date: 20 July 2001)

Interaction of the protein phosphatase 2A with the regulatory domain of the cystic fibrosis transmembrane conductance regulator channel

scientific article

Live-cell imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regulators in human cells

scientific article

Loss of protein phosphatase 2A regulatory subunit B56δ promotes spontaneous tumorigenesis in vivo.

scientific article

Mice lacking phosphatase PP2A subunit PR61/B'delta (Ppp2r5d) develop spatially restricted tauopathy by deregulation of CDK5 and GSK3beta

scientific article

Molecular implication of PP2A and Pin1 in the Alzheimer's disease specific hyperphosphorylation of Tau.

scientific article

PP1 and PP2A phosphatases--cooperating partners in modulating retinoblastoma protein activation

scientific article

PP2A Inactivation Mediated by PPP2R4 Haploinsufficiency Promotes Cancer Development

scientific article

PP2A binds to the LIM domains of lipoma-preferred partner through its PR130/B″ subunit to regulate cell adhesion and migration.

scientific article published on 04 March 2016

PP2A regulatory subunit Bα controls endothelial contractility and vessel lumen integrity via regulation of HDAC7.

scientific article

PP2A: A Promising Biomarker and Therapeutic Target in Endometrial Cancer

scientific article published on 04 June 2019

Physiologic functions of PP2A: Lessons from genetically modified mice

scientific article published on 18 July 2018

Protein kinase D displays intrinsic Tyr autophosphorylation activity: insights into mechanism and regulation

scientific article published on 23 July 2018

Protein phosphatase 2A PR130/B''alpha1 subunit binds to the SH2 domain-containing inositol polyphosphate 5-phosphatase 2 and prevents epidermal growth factor (EGF)-induced EGF receptor degradation sustaining EGF-mediated signaling.

scientific article

Protein phosphatase 2A controls the activity of histone deacetylase 7 during T cell apoptosis and angiogenesis

scientific article

Protein phosphatase 2A regulates deoxycytidine kinase activity via Ser-74 dephosphorylation.

scientific article published on 23 January 2014

Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling

scientific article

Recurrent PPP2R1A Mutations in Uterine Cancer Act through a Dominant-Negative Mechanism to Promote Malignant Cell Growth.

scientific article published on 2 August 2016

Reversible Ser/Thr SHIP phosphorylation: A new paradigm in phosphoinositide signalling?

scientific article published on 29 May 2012

Selection of Protein Phosphatase 2A Regulatory Subunits Is Mediated by the C Terminus of the Catalytic Subunit

scientific article published in Journal of Biological Chemistry

Spatial control of protein phosphatase 2A (de)methylation.

scientific article published on 7 August 2007

Specific interactions of PP2A and PP2A-like phosphatases with the yeast PTPA homologues, Ypa1 and Ypa2.

scientific article published on February 2005

Targeted Therapies in Type II Endometrial Cancers: Too Little, but Not Too Late

scientific article published in 2018

Targeted disruption of the mouse Lipoma Preferred Partner gene.

scientific article published on 26 December 2008

The B''/PR72 subunit mediates Ca2+-dependent dephosphorylation of DARPP-32 by protein phosphatase 2A.

scholarly article

The Basic Biology of PP2A in Hematologic Cells and Malignancies

scientific article

The Saccharomyces cerevisiae homologue YPA1 of the mammalian phosphotyrosyl phosphatase activator of protein phosphatase 2A controls progression through the G1 phase of the yeast cell cycle.

scientific article published in September 2000

The broad phenotypic spectrum of PPP2R1A-related neurodevelopmental disorders correlates with the degree of biochemical dysfunction

scientific article published on 27 October 2020

The phosphotyrosyl phosphatase activator gene is a novel p53 target gene

scientific article published on July 2000

The protein phosphatase 2A phosphatase activator is a novel peptidyl-prolyl cis/trans-isomerase.

scientific article

Tumor suppressive protein phosphatases in human cancer: Emerging targets for therapeutic intervention and tumor stratification

scientific article published on 11 October 2017