List of works - Hiromi Imamura

A Trace Amount of Galactose, a Major Component of Milk Sugar, Allows Maturation of Glycoproteins during Sugar Starvation

scientific article published on 23 November 2018

A Transient Rise in Free Mg2+ Ions Released from ATP-Mg Hydrolysis Contributes to Mitotic Chromosome Condensation.

scientific article published on 15 January 2018

ATP Maintenance via Two Types of ATP Regulators Mitigates Pathological Phenotypes in Mouse Models of Parkinson's Disease.

scientific article published on 25 July 2017

ATP increases within the lumen of the endoplasmic reticulum upon intracellular Ca2+ release

scientific article published on 04 December 2013

Analysis of mitochondrial function in human induced pluripotent stem cells from patients with mitochondrial diabetes due to the A3243G mutation

scientific article published on 17 January 2018

Application of FRET-Based Biosensor "ATeam" for Visualization of ATP Levels in the Mitochondrial Matrix of Living Mammalian Cells

scientific article published in January 2017

Assessing actual contribution of IF1, inhibitor of mitochondrial FoF1, to ATP homeostasis, cell growth, mitochondrial morphology, and cell viability

scientific article

Associative Interactions in Crowded Solutions of Biopolymers Counteract Depletion Effects.

scientific article

Automatic Quantitative Segmentation of Myotubes Reveals Single-cell Dynamics of S6 Kinase Activation

scientific article published on 26 July 2018

BTeam, a Novel BRET-based Biosensor for the Accurate Quantification of ATP Concentration within Living Cells

scientific article published on 21 December 2016

Ca²⁺ regulation of mitochondrial ATP synthesis visualized at the single cell level

scientific article published on 28 April 2011

Cell competition with normal epithelial cells promotes apical extrusion of transformed cells through metabolic changes

scientific article published on 17 April 2017

Changes in cytosolic ATP levels and intracellular morphology during bacteria-induced hypersensitive cell death as revealed by real-time fluorescence microscopy imaging.

scientific article published on 31 August 2012

Cloning of the gene for inorganic pyrophosphatase from a thermoacidophilic archaeon, Sulfolobus sp. strain 7, and overproduction of the enzyme by coexpression of tRNA for arginine rare codon

scientific article published on December 1998

Correlation between the conformational states of F1-ATPase as determined from its crystal structure and single-molecule rotation

scholarly article

Crystal structure of a central stalk subunit C and reversible association/dissociation of vacuole-type ATPase

scientific article

Crystal structures of 4-alpha-glucanotransferase from Thermococcus litoralis and its complex with an inhibitor

scientific article (publication date: 23 May 2003)

Crystallization and preliminary X-ray analysis of cytosolic alpha-mannosidase from Thermotoga maritima

scientific article

Distinct intracellular Ca2+ dynamics regulate apical constriction and differentially contribute to neural tube closure

scientific article published on 20 February 2017

Diversity in ATP concentrations in a single bacterial cell population revealed by quantitative single-cell imaging

scientific article published on 6 October 2014

Evidence for rotation of V1-ATPase.

scholarly article

Fluorescence imaging of intra- and extra-cellular ATP

scientific article published on November 1, 2010

Fusion protein analysis reveals the precise regulation between Hsp70 and Hsp100 during protein disaggregation

scientific article published on 17 August 2017

General anesthetics cause mitochondrial dysfunction and reduction of intracellular ATP levels

scientific article published on 3 January 2018

Genetically encoded fluorescent thermosensors visualize subcellular thermoregulation in living cells

scientific article published on 13 October 2013

Glucose-stimulated single pancreatic islets sustain increased cytosolic ATP levels during initial Ca2+ influx and subsequent Ca2+ oscillations.

scientific article published on 3 December 2013

Glycolysis, but not Mitochondria, responsible for intracellular ATP distribution in cortical area of podocytes. ⬇️

scientific article published on 18 December 2015

High level expression of Thermococcus litoralis 4-alpha-glucanotransferase in a soluble form in Escherichia coli with a novel expression system involving minor arginine tRNAs and GroELS

scientific article published on 01 September 1999

Human AK2 links intracellular bioenergetic redistribution to the fate of hematopoietic progenitors

scientific article published on 17 February 2018

Identification of the catalytic residue of Thermococcus litoralis 4-alpha-glucanotransferase through mechanism-based labeling.

scientific article published in October 2001

Imaging of intracellular ATP using novel fluorescent probes

scientific article published in December 2009

In vivo fluorescent adenosine 5'-triphosphate (ATP) imaging of Drosophila melanogaster and Caenorhabditis elegans by using a genetically encoded fluorescent ATP biosensor optimized for low temperatures

scientific article published on 8 August 2013

Intracellular ATP levels in mouse cortical excitatory neurons varies with sleep-wake states

scientific article published on 07 September 2020

MRT letter: Expression of ATP sensor protein in Caenorhabditis elegans

scientific article published on 28 October 2011

Mild Glucose Starvation Induces KDM2A-Mediated H3K36me2 Demethylation through AMPK To Reduce rRNA Transcription and Cell Proliferation

scientific article

Mitochondrial dysfunction in primary human fibroblasts triggers an adaptive cell survival program that requires AMPK-α.

scientific article published on 20 December 2014

Mitochondrial dysfunction induces dendritic loss via eIF2α phosphorylation

scientific article published on 16 February 2017

Molecular evolution of the ATPase subunit of three archaeal sugar ABC transporters

scientific article

Monitoring ATP dynamics in electrically active white matter tracts

scientific article published on 17 April 2017

OLIVe: A Genetically Encoded Fluorescent Biosensor for Quantitative Imaging of Branched-Chain Amino Acid Levels inside Single Living Cells

scientific article published on 17 December 2019

PPARα-Mediated Positive-Feedback Loop Contributes to Cold Exposure Memory

scientific article published on 14 March 2019

Principal role of the arginine finger in rotary catalysis of F1-ATPase.

scientific article published on 8 March 2012

Quantitative Glucose and ATP Sensing in Mammalian Cells ⬇️

scientific article published on June 21, 2011

RLR-mediated antiviral innate immunity requires oxidative phosphorylation activity

scientific article

Reconstitution in vitro of V1 complex of Thermus thermophilus V-ATPase revealed that ATP binding to the A subunit is crucial for V1 formation

scientific article published on 18 October 2006

Reliable imaging of ATP in living budding and fission yeast

scientific article published on 17 April 2019

Reversible dimerization of Aequorea victoria fluorescent proteins increases the dynamic range of FRET-based indicators

scientific article published in February 2010

Role of PFKFB3-driven glycolysis in vessel sprouting

scientific article

Rotation of the proteolipid ring in the V-ATPase

scientific article published on 21 April 2003

Rotation scheme of V1-motor is different from that of F1-motor.

scientific article

Rotation, structure, and classification of prokaryotic V-ATPase.

scientific article

Shear stress augments mitochondrial ATP generation that triggers ATP release and Ca2+ signaling in vascular endothelial cells

scientific article published on 24 August 2018

Single-cell dynamics of pannexin-1-facilitated programmed ATP loss during apoptosis

scientific article published on 14 October 2020

Spatiotemporal correlations between cytosolic and mitochondrial Ca(2+) signals using a novel red-shifted mitochondrial targeted cameleon

scientific article

Spindle pole body movement is affected by glucose and ammonium chloride in fission yeast

scientific article published on 04 March 2019

Structure of a central stalk subunit F of prokaryotic V-type ATPase/synthase from Thermus thermophilus

scientific article

Subunit arrangement in V-ATPase from Thermus thermophilus

scientific article published on 11 August 2003

The Plasma Membrane Calcium Pump in Pancreatic Cancer Cells Exhibiting the Warburg Effect Relies on Glycolytic ATP.

scientific article

Toll-like receptor 9 protects non-immune cells from stress by modulating mitochondrial ATP synthesis through the inhibition of SERCA2

scientific article

Transglycosylation activity of Dictyoglomus thermophilum amylase A.

scientific article published in November 2004

Unique metal dependency of cytosolic alpha-mannosidase from Thermotoga maritima, a hyperthermophilic bacterium.

scientific article published on July 2003

Visualization and Measurement of ATP Levels in Living Cells Replicating Hepatitis C Virus Genome RNA ⬇️

scientific article published on January 1, 2012

Visualization of ATP levels inside single living cells with fluorescence resonance energy transfer-based genetically encoded indicators

scientific article published on 31 August 2009

Visualization of NO3⁻/NO2⁻ Dynamics in Living Cells by Fluorescence Resonance Energy Transfer (FRET) Imaging Employing a Rhizobial Two-component Regulatory System.

scientific article

Visualization of long-term Mg2+ dynamics in apoptotic cells using a novel targetable fluorescent probe

scientific article published on 20 October 2017

[Two rotary molecular motors, V-ATPase and F0F1]

scientific article published on 01 May 2007

List of works by Hiromi Imamura

A Trace Amount of Galactose, a Major Component of Milk Sugar, Allows Maturation of Glycoproteins during Sugar Starvation

A Transient Rise in Free Mg2+ Ions Released from ATP-Mg Hydrolysis Contributes to Mitotic Chromosome Condensation.

ATP Maintenance via Two Types of ATP Regulators Mitigates Pathological Phenotypes in Mouse Models of Parkinson's Disease.

ATP increases within the lumen of the endoplasmic reticulum upon intracellular Ca2+ release

Analysis of mitochondrial function in human induced pluripotent stem cells from patients with mitochondrial diabetes due to the A3243G mutation

Application of FRET-Based Biosensor "ATeam" for Visualization of ATP Levels in the Mitochondrial Matrix of Living Mammalian Cells

Assessing actual contribution of IF1, inhibitor of mitochondrial FoF1, to ATP homeostasis, cell growth, mitochondrial morphology, and cell viability

Associative Interactions in Crowded Solutions of Biopolymers Counteract Depletion Effects.

Automatic Quantitative Segmentation of Myotubes Reveals Single-cell Dynamics of S6 Kinase Activation

BTeam, a Novel BRET-based Biosensor for the Accurate Quantification of ATP Concentration within Living Cells

Ca²⁺ regulation of mitochondrial ATP synthesis visualized at the single cell level

Cell competition with normal epithelial cells promotes apical extrusion of transformed cells through metabolic changes

Changes in cytosolic ATP levels and intracellular morphology during bacteria-induced hypersensitive cell death as revealed by real-time fluorescence microscopy imaging.

Cloning of the gene for inorganic pyrophosphatase from a thermoacidophilic archaeon, Sulfolobus sp. strain 7, and overproduction of the enzyme by coexpression of tRNA for arginine rare codon

Correlation between the conformational states of F1-ATPase as determined from its crystal structure and single-molecule rotation

Crystal structure of a central stalk subunit C and reversible association/dissociation of vacuole-type ATPase

Crystal structures of 4-alpha-glucanotransferase from Thermococcus litoralis and its complex with an inhibitor

Crystallization and preliminary X-ray analysis of cytosolic alpha-mannosidase from Thermotoga maritima

Distinct intracellular Ca2+ dynamics regulate apical constriction and differentially contribute to neural tube closure

Diversity in ATP concentrations in a single bacterial cell population revealed by quantitative single-cell imaging

Evidence for rotation of V1-ATPase.

Fluorescence imaging of intra- and extra-cellular ATP

Fusion protein analysis reveals the precise regulation between Hsp70 and Hsp100 during protein disaggregation

General anesthetics cause mitochondrial dysfunction and reduction of intracellular ATP levels

Genetically encoded fluorescent thermosensors visualize subcellular thermoregulation in living cells

Glucose-stimulated single pancreatic islets sustain increased cytosolic ATP levels during initial Ca2+ influx and subsequent Ca2+ oscillations.

Glycolysis, but not Mitochondria, responsible for intracellular ATP distribution in cortical area of podocytes. ⬇️

High level expression of Thermococcus litoralis 4-alpha-glucanotransferase in a soluble form in Escherichia coli with a novel expression system involving minor arginine tRNAs and GroELS

Human AK2 links intracellular bioenergetic redistribution to the fate of hematopoietic progenitors

Identification of the catalytic residue of Thermococcus litoralis 4-alpha-glucanotransferase through mechanism-based labeling.

Imaging of intracellular ATP using novel fluorescent probes

In vivo fluorescent adenosine 5'-triphosphate (ATP) imaging of Drosophila melanogaster and Caenorhabditis elegans by using a genetically encoded fluorescent ATP biosensor optimized for low temperatures

Intracellular ATP levels in mouse cortical excitatory neurons varies with sleep-wake states

MRT letter: Expression of ATP sensor protein in Caenorhabditis elegans

Mild Glucose Starvation Induces KDM2A-Mediated H3K36me2 Demethylation through AMPK To Reduce rRNA Transcription and Cell Proliferation

Mitochondrial dysfunction in primary human fibroblasts triggers an adaptive cell survival program that requires AMPK-α.

Mitochondrial dysfunction induces dendritic loss via eIF2α phosphorylation

Molecular evolution of the ATPase subunit of three archaeal sugar ABC transporters

Monitoring ATP dynamics in electrically active white matter tracts

OLIVe: A Genetically Encoded Fluorescent Biosensor for Quantitative Imaging of Branched-Chain Amino Acid Levels inside Single Living Cells

PPARα-Mediated Positive-Feedback Loop Contributes to Cold Exposure Memory

Principal role of the arginine finger in rotary catalysis of F1-ATPase.

Quantitative Glucose and ATP Sensing in Mammalian Cells ⬇️

RLR-mediated antiviral innate immunity requires oxidative phosphorylation activity

Reconstitution in vitro of V1 complex of Thermus thermophilus V-ATPase revealed that ATP binding to the A subunit is crucial for V1 formation

Reliable imaging of ATP in living budding and fission yeast

Reversible dimerization of Aequorea victoria fluorescent proteins increases the dynamic range of FRET-based indicators

Role of PFKFB3-driven glycolysis in vessel sprouting

Rotation of the proteolipid ring in the V-ATPase

Rotation scheme of V1-motor is different from that of F1-motor.

Rotation, structure, and classification of prokaryotic V-ATPase.

Shear stress augments mitochondrial ATP generation that triggers ATP release and Ca2+ signaling in vascular endothelial cells

Single-cell dynamics of pannexin-1-facilitated programmed ATP loss during apoptosis

Spatiotemporal correlations between cytosolic and mitochondrial Ca(2+) signals using a novel red-shifted mitochondrial targeted cameleon

Spindle pole body movement is affected by glucose and ammonium chloride in fission yeast

Structure of a central stalk subunit F of prokaryotic V-type ATPase/synthase from Thermus thermophilus

Subunit arrangement in V-ATPase from Thermus thermophilus

The Plasma Membrane Calcium Pump in Pancreatic Cancer Cells Exhibiting the Warburg Effect Relies on Glycolytic ATP.

Toll-like receptor 9 protects non-immune cells from stress by modulating mitochondrial ATP synthesis through the inhibition of SERCA2

Transglycosylation activity of Dictyoglomus thermophilum amylase A.

Unique metal dependency of cytosolic alpha-mannosidase from Thermotoga maritima, a hyperthermophilic bacterium.

Visualization and Measurement of ATP Levels in Living Cells Replicating Hepatitis C Virus Genome RNA ⬇️

Visualization of ATP levels inside single living cells with fluorescence resonance energy transfer-based genetically encoded indicators

Visualization of NO3⁻/NO2⁻ Dynamics in Living Cells by Fluorescence Resonance Energy Transfer (FRET) Imaging Employing a Rhizobial Two-component Regulatory System.

Visualization of long-term Mg2+ dynamics in apoptotic cells using a novel targetable fluorescent probe

[Two rotary molecular motors, V-ATPase and F0F1]