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List of works by Bradley A. Edwards

A dynamic model for assessing the impact of diffusing capacity on arterial oxygenation during apnea.

scientific article published on 10 April 2010

A graphical method for comparing nocturnal oxygen saturation profiles in individuals and populations: Application to healthy infants and preterm neonates.

scientific article published on 24 March 2018

A model analysis of arterial oxygen desaturation during apnea in preterm infants

scientific article

A model investigation of the impact of ventilation-perfusion mismatch on oxygenation during apnea in preterm infants.

scientific article published in April 2010

A model of coronary artery endothelial dysfunction in the sleeping lamb.

scientific article published on 22 September 2006

A simplified method for determining phenotypic traits in patients with obstructive sleep apnea.

scientific article published on 24 January 2013

A single dose of noradrenergic/serotonergic reuptake inhibitors combined with an antimuscarinic does not improve obstructive sleep apnoea severity

scientific article published in 2022

Acetazolamide attenuates Hunter-Cheyne-Stokes breathing but augments the hypercapnic ventilatory response in patients with heart failure

scientific article

Acetazolamide improves loop gain but not the other physiological traits causing obstructive sleep apnoea.

scientific article published on 4 January 2012

Adapting our approach to treatment-emergent central sleep apnea

scientific article published in August 2013

An Integrative Model of Physiological Traits Can be Used to Predict Obstructive Sleep Apnea and Response to Non Positive Airway Pressure Therapy.

scientific article published on June 2015

Assessing the impact of diet, exercise and the combination of the two as a treatment for OSA: A systematic review and meta-analysis

scientific article published on 22 May 2019

Assessing ventilatory control stability in children with and without an elevated central apnoea index

scientific article published on 30 May 2019

Assessing ventilatory instability using the response to spontaneous sighs during sleep in preterm infants

scientific article published on 01 November 2018

Blood pressure improvement with continuous positive airway pressure is independent of obstructive sleep apnea severity

scientific article published on 15 April 2014

Clinical polysomnographic methods for estimating pharyngeal collapsibility in obstructive sleep apnea

scientific article published in 2022

Clinical predictors of the respiratory arousal threshold in patients with obstructive sleep apnea.

scientific article

Continuous positive airway pressure reduces loop gain and resolves periodic central apneas in the lamb

scientific article published on 16 July 2009

Control of the pharyngeal musculature during wakefulness and sleep: implications in normal controls and sleep apnea.

scientific article

Control theory prediction of resolved Cheyne-Stokes respiration in heart failure

scientific article

CrossTalk opposing view: Loop gain is not a consequence of obstructive sleep apnoea

scientific article published in July 2014

Desipramine Increases Genioglossus Activity and Reduces Upper Airway Collapsibility during Non-REM Sleep in Healthy Subjects

scientific article published on 11 March 2016

Desipramine improves upper airway collapsibility and reduces OSA severity in patients with minimal muscle compensation

scientific article published on 6 October 2016

Differences in respiratory arousal threshold in Caucasian and Chinese patients with obstructive sleep apnoea

scientific article

Does pressure affect performance? Continuous positive airway pressure for sleep-disordered breathing in heart failure.

scientific article published in January 2014

Dynamic loop gain increases upon adopting the supine body position during sleep in patients with obstructive sleep apnoea

scientific article published on 20 July 2017

Effect of 4-Aminopyridine on Genioglossus Muscle Activity during Sleep in Healthy Adults

scientific article

Effect of Hypopnea Scoring Criteria on Noninvasive Assessment of Loop Gain and Surgical Outcome Prediction

scientific article published on 01 April 2020

Effects of Tiagabine on Slow Wave Sleep and Arousal Threshold in Patients With Obstructive Sleep Apnea

scientific article

Effects of hyperoxia and hypoxia on the physiological traits responsible for obstructive sleep apnoea

scientific article

Enhanced upper-airway muscle responsiveness is a distinct feature of overweight/obese individuals without sleep apnea

scientific article

Estimation of Pharyngeal Collapsibility During Sleep by Peak Inspiratory Airflow

scientific article

Evaluation of the role of lung volume and airway size and shape in supine-predominant obstructive sleep apnoea patients

scientific article published on 4 May 2015

Examining the impact of multilevel upper airway surgery on the obstructive sleep apnoea endotypes and their utility in predicting surgical outcomes

scientific article published in 2022

Expiratory resistance increases end-expiratory lung volume during sleep

scientific article published on April 2012

Identifying obstructive sleep apnoea patients responsive to supplemental oxygen therapy

scientific article published on 27 September 2018

Improvement in Obstructive Sleep Apnea With Weight Loss is Dependent on Body Position During Sleep.

scientific article published on 21 April 2017

Increased peripheral chemosensitivity via dopaminergic manipulation promotes respiratory instability in lambs

scientific article published on 7 September 2008

Influence of pharyngeal muscle activity on inspiratory negative effort dependence in the human upper airway.

scientific article

Is there a threshold that triggers cortical arousals in obstructive sleep apnea

scientific article published on 01 June 2019

Journey towards a personalised medicine approach for OSA: Can a similar approach to adult OSA be applied to paediatric OSA?

scientific article published on 14 February 2020

Laboratory performance of oronasal CPAP and adapted snorkel masks to entrain oxygen and CPAP

scientific article published on 03 August 2020

Loop Gain Predicts the Response to Upper Airway Surgery in Patients With Obstructive Sleep Apnea.

scientific article published on 22 May 2017

Loop gain as a means to predict a positive airway pressure suppression of Cheyne-Stokes respiration in patients with heart failure.

scientific article published in November 2011

Maturation of respiratory control and the propensity for breathing instability in a sheep model

scientific article published on 10 September 2009

Measuring Loop Gain via Home Sleep Testing in Patients with Obstructive Sleep Apnea.

scientific article published on 30 November 2017

Mechanism underlying accelerated arterial oxygen desaturation during recurrent apnea.

scientific article published on 3 June 2010

Model-based characterization of ventilatory stability using spontaneous breathing.

scientific article

Model-based estimation of loop gain using spontaneous breathing: a validation study.

scientific article

More Than the Sum of the Respiratory Events: Personalized Medicine Approaches for Obstructive Sleep Apnea

scientific article published on 01 September 2019

Obstructive sleep apnea in older adults is a distinctly different physiological phenotype

scientific article

Obstructive sleep apnoea pathogenesis from mild to severe: Is it all the same?

scientific article

Oronasal Masks Require a Higher Pressure than Nasal and Nasal Pillow Masks for the Treatment of Obstructive Sleep Apnea

scientific article published on 19 July 2016

Oxygen Desaturation Index Differs Significantly Between Types of Sleep Software.

scientific article published on 15 February 2017

PSGs: more than just the AHI.

scientific article published on 15 June 2013

Phenotyping Pharyngeal Pathophysiology Using Polysomnography in Patients with Obstructive Sleep Apnea

scientific article published on 12 January 2018

Point of emission air filtration enhances protection of healthcare workers against skin contamination with virus aerosol

scientific article published in 2022

Polysomnographic Endotyping to Select Patients with Obstructive Sleep Apnea for Oral Appliances

scientific article published on 01 November 2019

Positional modification techniques for supine obstructive sleep apnea: A systematic review and meta-analysis.

scientific article published on 18 November 2016

Predicting sleep apnea responses to oral appliance therapy using polysomnographic airflow

scientific article published on 10 February 2020

Prevalence, Associated Clinical Features, and Impact on Continuous Positive Airway Pressure Use of a Low Respiratory Arousal Threshold Among Male United States Veterans With Obstructive Sleep Apnea

scientific article published on 15 May 2018

Quantifying the Arousal Threshold using Polysomnography in Obstructive Sleep Apnea

scientific article published on 9 November 2017

Quantifying the ventilatory control contribution to sleep apnoea using polysomnography

scientific article

Quantifying ventilatory control stability from spontaneous sigh responses during sleep: a comparison of two approaches

scientific article published on 22 November 2018

Rebuttal from J. E. Orr, B. A. Edwards and A. Malhotra

scientific article published in July 2014

Reply 2.

scientific article

Resonance as the Mechanism of Daytime Periodic Breathing in Patients with Heart Failure.

scientific article

Response to a combination of oxygen and a hypnotic as treatment for obstructive sleep apnoea is predicted by a patient's therapeutic CPAP requirement

scientific article published on 13 April 2017

Role of ventilatory control instability in children with sleep-disordered breathing

scientific article published on 02 April 2020

Test of the Starling resistor model in the human upper airway during sleep

scientific article

The Arousal Threshold as a Drug-Target to Improve CPAP Adherence: Secondary Analysis of a Randomized Trial

scientific article published on 16 July 2020

The Combination of Supplemental Oxygen and a Hypnotic Markedly Improves Obstructive Sleep Apnea in Patients with a Mild to Moderate Upper Airway Collapsibility.

scientific article published on 09 September 2016

The Effect of Body Position on Physiological Factors that Contribute to Obstructive Sleep Apnea.

scientific article

The Effect of Hypopnea Scoring on the Arousal Threshold in Patients with Obstructive Sleep Apnea

scientific article published on 18 June 2020

The classical Starling resistor model often does not predict inspiratory airflow patterns in the human upper airway

scientific article

The physiological phenotype of obstructive sleep apnea differs between Caucasian and Chinese patients

scientific article published on 01 October 2019

The relationship between partial upper-airway obstruction and inter-breath transition period during sleep.

scientific article

Therapeutic CPAP Level Predicts Upper Airway Collapsibility in Patients With Obstructive Sleep Apnea

scientific article published on 13 April 2017

Trazodone Effects on Obstructive Sleep Apnea and Non-REM Arousal Threshold.

scientific article published on May 2015

Tube Law of the Pharyngeal Airway in Sleeping Patients with Obstructive Sleep Apnea

scientific article

Understanding the Physiological Endotypes Responsible for Co-Morbid Obstructive Sleep Apnea in Patients with Interstitial Lung Disease

scientific article published in 2023

Upper-Airway Collapsibility and Loop Gain Predict the Response to Oral Appliance Therapy in Patients with Obstructive Sleep Apnea.

scientific article published on 15 May 2016

Ventilatory control sensitivity in patients with obstructive sleep apnea is sleep stage dependent

scientific article published on 01 May 2018

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