Search filters

List of works by Gen Inoue

18F-fluorodeoxyglucose-PET for patients with suspected spondylitis showing Modic change

scientific article published on December 2010

A case of symptomatic extra-foraminal lumbosacral stenosis ("far-out syndrome") diagnosed by diffusion tensor imaging.

scientific article published in June 2012

Acute lumbar spinal pseudogout attack after instrumented surgery

scientific article published in November 2012

Additional decompression at adjacent segments leads to adjacent segment degeneration after PLIF.

scientific article published on 13 February 2013

Answer to the Letter to the Editor of Wang Kai et al. concerning "Radiographic evaluation of indirect decompression of mini-open anterior retroperitoneal lumbar interbody fusion: oblique lateral interbody fusion for degenerated lumbar spondylolisthe

scientific article published on 20 October 2017

Anterolateral Corrective Lumbar Corpectomy and Interbody Fusion by Using Extended Screw Fixation without Posterior Instrumentation for Posttraumatic Kyphosis

scientific article published on 18 July 2013

Anti-RANKL antibodies decrease CGRP expression in dorsal root ganglion neurons innervating injured lumbar intervertebral discs in rats.

scientific article published on 14 June 2015

Assessment of gait in a rat model of myofascial inflammation using the CatWalk system

scientific article published in October 2011

Assessment of pain behavior in a rat model of intervertebral disc injury using the CatWalk gait analysis system

scientific article

Associations between proinflammatory cytokines in the synovial fluid and radiographic grading and pain-related scores in 47 consecutive patients with osteoarthritis of the knee

scientific article

Basic Fibroblast Growth Factor Fused with Tandem Collagen-Binding Domains from Clostridium histolyticum Collagenase ColG Increases Bone Formation.

scientific article published on 25 March 2018

Basic Fibroblast Growth Factor-Anchored Multilayered Mesenchymal Cell Sheets Accelerate Periosteal Bone Formation

scientific article published on 6 July 2017

Brain-derived neurotrophic factor inhibition at the punctured intervertebral disc downregulates the production of calcitonin gene-related peptide in dorsal root ganglia in rats

scientific article

Change in Modic type 1 and 2 signals after posterolateral fusion surgery

scientific article published on 01 May 2010

Change of Lumbar Ligamentum Flavum after Indirect Decompression Using Anterior Lumbar Interbody Fusion

scientific article published on 17 February 2017

Characteristics of sensory dorsal root ganglia neurons innervating the lumbar vertebral body in rats

scientific article published on 26 March 2007

Classification of Chronic Back Muscle Degeneration after Spinal Surgery and Its Relationship with Low Back Pain

scientific article

Clinical incidence of sacroiliac joint arthritis and pain after sacropelvic fixation for spinal deformity

scientific article published on March 2012

Common iliac vein injury during L5-S1 posterior lumbar interbody fusion in a patient with systemic lupus erythematosus receiving steroid treatment: A case report

scientific article published on 14 January 2016

Comparison of CatWalk analysis and von Frey testing for pain assessment in a rat model of nerve crush plus inflammation

scientific article published in July 2013

Comparison of teriparatide and bisphosphonate treatment to reduce pedicle screw loosening after lumbar spinal fusion surgery in postmenopausal women with osteoporosis from a bone quality perspective

scientific article

Conservative and surgical treatment improves pain and ankle-brachial index in patients with lumbar spinal stenosis

scientific article published on July 2013

Cost-effectiveness analysis of the pharmacological management of chronic low back pain with four leading drugs

scientific article published on 21 June 2019

Decreased calcitonin gene-related peptide expression in the dorsal root ganglia of TNF-deficient mice in a monoiodoacetate-induced knee osteoarthritis model

scientific article published on October 2015

Degeneration and recovery of the neuromuscular junction after application of extracorporeal shock wave therapy ⬇️

scientific article published on March 27, 2012

Delayed postoperative epidural hematoma presenting only with vesicorectal disturbance.

scientific article published on September 2013

Delayed surgical treatment for a traumatic bilateral cervical facet joint dislocation using a posterior-anterior approach: a case report ⬇️

scientific article published on January 9, 2013

Dichotomizing sensory nerve fibers innervating both the lumbar vertebral body and the area surrounding the iliac crest: a possible mechanism of referred lateral back pain from lumbar vertebral body

scientific article

Differences between tumor necrosis factor-α receptors types 1 and 2 in the modulation of spinal glial cell activation and mechanical allodynia in a rat sciatic nerve injury model

scientific article published on January 2013

Differences in damage to CGRP immunoreactive sensory nerves after two lumbar surgical approaches: investigation using humans and rats

scientific article published in February 2012

Difficulty of diagnosing the origin of lower leg pain in patients with both lumbar spinal stenosis and hip joint osteoarthritis

scientific article

Diffusion magnetic resonance imaging to differentiate degenerative from infectious endplate abnormalities in the lumbar spine

scientific article published on 01 February 2011

Diffusion tensor imaging of lumbar spinal nerve in subjects with degenerative lumbar disorders.

scientific article published on 12 May 2015

Diffusion-weighted magnetic resonance imaging of symptomatic nerve root of patients with lumbar disk herniation.

scientific article published on 16 November 2010

Direct application of the TNF-alpha inhibitor, etanercept, does not affect CGRP expression and phenotypic change of DRG neurons following application of nucleus pulposus onto injured sciatic nerves in rats

scientific article published on 01 October 2008

Direct application of the tumor necrosis factor-α inhibitor, etanercept, into a punctured intervertebral disc decreases calcitonin gene-related peptide expression in rat dorsal root ganglion neurons

scientific article published in January 2011

Direct evidence for sensory innervation of the dorsal portion of the Co5/6 coccygeal intervertebral disc in rats

scientific article published on 01 June 2010

Direct single injection of p38 mitogen-activated protein kinase inhibitor does not affect calcitonin gene-related peptide expression in dorsal root ganglion neurons innervating punctured discs in rats

scientific article

Disk injury in rats produces persistent increases in pain-related neuropeptides in dorsal root ganglia and spinal cord glia but only transient increases in inflammatory mediators: pathomechanism of chronic diskogenic low back pain

scientific article published in December 2011

Do Physical Symptoms Predict the Outcome of Surgical Fusion in Patients with Discogenic Low Back Pain?

scientific article published on 16 June 2016

Effect of Single Injection of Recombinant Human Bone Morphogenetic Protein-2-Loaded Artificial Collagen-Like Peptide in a Mouse Segmental Bone Transport Model

scientific article published on 23 December 2019

Effect of applying p75NTR saporin to a punctured intervertebral disc on calcitonin gene-related peptide expression in rat dorsal root ganglion neurons

scientific article published in May 2010

Effectiveness of L2 spinal nerve infiltration for selective discogenic low back pain patients

scientific article

Efficacy of Anti-NaV1.7 Antibody on the Sensory Nervous System in a Rat Model of Lumbar Intervertebral Disc Injury

scientific article published on May 2016

Efficacy of Direct Injection of Etanercept into Knee Joints for Pain in Moderate and Severe Knee Osteoarthritis

scientific article

Efficacy of anti-nerve growth factor therapy for discogenic neck pain in rats

scientific article published on 01 June 2014

Efficacy of combination of meloxicam and pregabalin for pain in knee osteoarthritis

scientific article published on September 2013

Efficacy of epidural administration of anti-interleukin-6 receptor antibody onto spinal nerve for treatment of sciatica

scientific article

Efficacy of nerve growth factor antibody in a knee osteoarthritis pain model in mice.

scientific article published on 3 November 2017

English publication rate of 3,205 abstracts presented at the Annual Meeting of the Japanese Orthopaedic Association and the Annual Research Meeting of the Japanese Orthopaedic Association

scientific article published on 20 July 2013

Epidural administration of spinal nerves with the tumor necrosis factor-alpha inhibitor, etanercept, compared with dexamethasone for treatment of sciatica in patients with lumbar spinal stenosis: a prospective randomized study

scientific article

Erythropoietin promotes Schwann cell migration and assembly of the provisional extracellular matrix by recruiting beta1 integrin to the cell surface

scientific journal article

Evaluation of Lumbar Intervertebral Disc Degeneration Using T1ρ and T2 Magnetic Resonance Imaging in a Rabbit Disc Injury Model.

scientific article

Evaluation of behavior and expression of NaV1.7 in dorsal root ganglia after sciatic nerve compression and application of nucleus pulposus in rats

scientific article

Evaluation of behavior and expression of receptor activator of nuclear factor-kappa B ligand in dorsal root Ganglia after sciatic nerve compression and application of nucleus pulposus in rats

scientific article

Evaluation of behavior and neuropeptide markers of pain in a simple, sciatic nerve-pinch pain model in rats.

scientific article

Evaluation of pain behavior and calcitonin gene-related peptide immunoreactive sensory nerve fibers in the spinal dorsal horn after sciatic nerve compression and application of nucleus pulposus in rats

scientific article

Existence of a neuropathic pain component in patients with osteoarthritis of the knee

scientific article

Existence of nerve growth factor receptors, tyrosine kinase a and p75 neurotrophin receptors in intervertebral discs and on dorsal root ganglion neurons innervating intervertebral discs in rats

scientific article published in September 2008

Existence of pyogenic spondylitis in Modic type 1 change without other signs of infection: 2-year follow-up

scientific article

Exposure of the nucleus pulposus to the outside of the anulus fibrosus induces nerve injury and regeneration of the afferent fibers innervating the lumbar intervertebral discs in rats

scientific article published on 01 June 2006

Glial phosphorylated p38 MAP kinase mediates pain in a rat model of lumbar disc herniation and induces motor dysfunction in a rat model of lumbar spinal canal stenosis

scientific article published on 01 January 2007

Hyaluronic Acid (800 kDa) Supplementation of University of Wisconsin Solution Improves Viability of Osteochondral Grafts and Reduces Matrix Metalloproteinase Expression during Cold Preservation

scientific article published on 25 June 2015

Hydrogen supplementation of preservation solution improves viability of osteochondral grafts

scientific article

ISSLS prize winner: disc dynamic compression in rats produces long-lasting increases in inflammatory mediators in discs and induces long-lasting nerve injury and regeneration of the afferent fibers innervating discs: a pathomechanism for chronic dis

scientific article

Impact of background factors on outcomes of pharmacological therapy for chronic low back pain: A nationwide multicenter prospective study

scientific article published on 28 February 2020

In-vivo transfection of the proopiomelanocortin gene, precursor of endogenous endorphin, by use of radial shock waves alleviates neuropathic pain

scientific article published on 27 April 2013

Incidence of nocturnal leg cramps in patients with lumbar spinal stenosis before and after conservative and surgical treatment

scientific article published on April 2014

Increase in mast cell marker expression in the synovium of obese patients with osteoarthritis of the knee

scientific article published on 21 March 2019

Increase of TRPV1-immunoreactivity in dorsal root ganglia neurons innervating the femur in a rat model of osteoporosis

scientific article

Inhibiting IκB kinase-β downregulates inflammatory cytokines in injured discs and neuropeptides in dorsal root ganglia innervating injured discs in rats

scientific article published in July 2014

Inhibiting nerve growth factor or its receptors downregulates calcitonin gene-related peptide expression in rat lumbar dorsal root ganglia innervating injured intervertebral discs.

scientific article

Injection of bupivacaine into disc space to detect painful nonunion after anterior lumbar interbody fusion (ALIF) surgery in patients with discogenic low back pain

scientific article published on March 2014

Injection of nuclear factor-kappa B decoy into the sciatic nerve suppresses mechanical allodynia and thermal hyperalgesia in a rat inflammatory pain model

scientific article published in December 2006

Insertional torque of the lumbar pedicle screw during surgery

scientific article published in January 2005

Interleukin-6 and interleukin-6 receptor expression, localization, and involvement in pain-sensing neuron activation in a mouse intervertebral disc injury model

scientific article published on 29 May 2015

Interspinous Ligament Lidocaine and Steroid Injections for the Management of Baastrup's Disease: A Case Series

scientific article published on 9 June 2014

Investigation of dichotomizing sensory nerve fibers projecting to the lumbar multifidus muscles and intervertebral disc or facet joint or sacroiliac joint in rats

scientific article

IκB kinase β inhibitor downregulates pain-related neuropeptide production in the sensory neurons innervating injured lumbar intervertebral discs in the dorsal root ganglia of rats

scientific article published on 23 February 2013

L2 spinal nerve-block effects on acute low back pain from osteoporotic vertebral fracture

scientific article published in August 2009

L5 spinal nerve injury caused by misplacement of outwardly-inserted S1 pedicle screws

scientific article published on 28 December 2012

Less invasive corrective surgery using oblique lateral interbody fusion (OLIF) including L5-S1 fusion for severe lumbar kyphoscoliosis due to L4 compression fracture in a patient with Parkinson's disease: a case report

scientific article published on 7 April 2015

Limitations of posterior spinal fusion to L5 for flaccid neuromuscular scoliosis focusing on pelvic obliquity

scientific article published on 02 October 2020

Long-term intravenous administration of antibiotics for lumbar spinal surgery prolongs the duration of hospital stay and time to normalize body temperature after surgery

scientific article published in December 2008

Low affinity NGF receptor (p75 neurotrophin receptor) inhibitory antibody reduces pain behavior and CGRP expression in DRG in the mouse sciatic nerve crush model

scientific article published on 01 March 2010

Low back pain after lumbar discectomy in patients showing endplate modic type 1 change

scientific article published in June 2010

Lumbar disc degeneration induces persistent groin pain

scientific article

Lumbar posterolateral fusion inhibits sensory nerve ingrowth into punctured lumbar intervertebral discs and upregulation of CGRP immunoreactive DRG neuron innervating punctured discs in rats

scientific article

Mini-Open Anterior Retroperitoneal Lumbar Interbody Fusion: Oblique Lateral Interbody Fusion for Degenerated Lumbar Spinal Kyphoscoliosis

scientific article published on 28 July 2015

Mini-Open Anterior Retroperitoneal Lumbar Interbody Fusion: Oblique Lateral Interbody Fusion for Lumbar Spinal Degeneration Disease

scientific article published on July 2015

Miniopen oblique lateral L5-s1 interbody fusion: a report of 2 cases

scientific article published on 21 October 2014

Modified Open-Door Laminoplasty Using a Ceramic Spacer and Suture Fixation for Cervical Myelopathy

scientific article

More than 6 Months of Teriparatide Treatment Was More Effective for Bone Union than Shorter Treatment Following Lumbar Posterolateral Fusion Surgery

scientific article published on 28 July 2015

Muscle injury in rats induces upregulation of inflammatory cytokines in injured muscle and calcitonin gene-related peptide in dorsal root ganglia innervating the injured muscle

scientific article published on March 2016

Nerve growth factor of cultured medium extracted from human degenerative nucleus pulposus promotes sensory nerve growth and induces substance p in vitro

scientific article published in October 2009

No acceleration of intervertebral disc degeneration after a single injection of bupivacaine in young age group with follow-up of 5 years

scientific article published on 4 September 2013

Nuclear factor-kappa B decoy suppresses nerve injury and improves mechanical allodynia and thermal hyperalgesia in a rat lumbar disc herniation model

scientific article

Occupational Characteristics of Low Back Pain Among Standing Workers in a Japanese Manufacturing Company

scientific article published on 09 July 2019

One, two-, and three-level instrumented posterolateral fusion of the lumbar spine with a local bone graft: a prospective study with a 2-year follow-up

scientific article published in August 2011

Oriented collagen tubes combined with basic fibroblast growth factor promote peripheral nerve regeneration in a 15 mm sciatic nerve defect rat model

scientific article published on 16 August 2016

Osteoarthritis patients with high haemoglobin A1c have increased Toll-like receptor 4 and matrix metalloprotease-13 expression in the synovium

scientific article published on 16 July 2019

Pain-related sensory innervation in monoiodoacetate-induced osteoarthritis in rat knees that gradually develops neuronal injury in addition to inflammatory pain

scientific article

PainVision Apparatus Is Effective for Assessing Low Back Pain

scientific article published on 17 December 2014

Pathomechanisms of discogenic low back pain in humans and animal models

scientific article published on 20 March 2014

Percutaneously absorbed NSAIDs attenuate local production of proinflammatory cytokines and suppress the expression of c-Fos in the spinal cord of a rodent model of knee osteoarthritis

scientific article published on 26 November 2011

Platelet-rich plasma combined with hydroxyapatite for lumbar interbody fusion promoted bone formation and decreased an inflammatory pain neuropeptide in rats

scientific article published in September 2012

Posterior and anterior spinal fusion for the management of deformities in patients with Parkinson's disease

scientific article published on 02 September 2013

Postoperative lumbar spinal stenosis after intertransverse fusion with granules of hydroxyapatite: a case report

scientific article published on 7 November 2012

Pregabalin for Refractory Radicular Leg Pain due to Lumbar Spinal Stenosis: A Preliminary Prospective Study

scientific article published on 29 March 2016

Primary sensory neurons with dichotomizing axons projecting to the facet joint and the low back muscle in rats

scientific article

Progressive change in joint degeneration in patients with knee or hip osteoarthritis treated with fentanyl in a randomized trial

scientific article

Proinflammatory cytokines in the cerebrospinal fluid of patients with lumbar radiculopathy

scientific article published on 17 October 2010

Radiographic and Clinical Outcomes From the Use of S2 Alar Screws in Surgery for Adult Spinal Deformity

scientific article published on 29 April 2018

Radiographic evaluation of indirect decompression of mini-open anterior retroperitoneal lumbar interbody fusion: oblique lateral interbody fusion for degenerated lumbar spondylolisthesis

scientific article published on 6 August 2015

Radiographic evaluation of monocortical versus tricortical purchase approaches in lumbosacral fixation with sacral pedicle screws: a prospective study of ninety consecutive patients

scientific article published in October 2010

Remarkable regression of a giant cell tumor of the cervical spine treated conservatively with denosumab: A case report

scientific article published on 10 May 2016

Remote Hemorrhage in the Cerebellum and Temporal Lobe after Lumbar Spine Surgery

scientific article published on 3 August 2015

Results of surgery for discogenic low back pain: a randomized study using discography versus discoblock for diagnosis

scientific article

Rho kinase inhibitor improves motor dysfunction and hypoalgesia in a rat model of lumbar spinal canal stenosis

scientific article published on 01 September 2007

Risedronate decreases bone resorption and improves low back pain in postmenopausal osteoporosis patients without vertebral fractures

scientific article published on 30 December 2009

Risk factors associated with prolonged intensive care unit stay after posterior spinal fusion for Duchenne muscular dystrophy

scientific article published on 21 April 2020

Risk factors for L5-S1 disk height reduction after lumbar posterolateral floating fusion surgery

scientific article published in July 2014

Rotational hypermobility of disc wedging using kinematic CT: preliminary study to investigate the instability of discs in degenerated scoliosis in the lumbar spine

scientific article

Sensory and autonomic innervation of the cervical intervertebral disc in rats: the pathomechanics of chronic discogenic neck pain.

scientific article published in July 2012

Sensory innervation and inflammatory cytokines in hypertrophic synovia associated with pain transmission in osteoarthritis of the hip: a case-control study

scientific article

Sensory innervation of lumbar vertebral bodies in rats

scientific article published in June 2007

Short-segment fixation without fusion for thoracolumbar burst fractures with neurological deficit can preserve thoracolumbar motion without resulting in post-traumatic disc degeneration: a 10-year follow-up study

scientific article published in August 2013

Single Intradiscal Administration of the Tumor Necrosis Factor-Alpha Inhibitor, Etanercept, for Patients with Discogenic Low Back Pain

scientific article

Single intradiscal injection of the interleukin-6 receptor antibody tocilizumab provides short-term relief of discogenic low back pain; prospective comparative cohort study

scientific article published on 19 November 2015

Single-level instrumented posterolateral fusion of the lumbar spine with a local bone graft versus an iliac crest bone graft: a prospective, randomized study with a 2-year follow-up

scientific article

Single-level instrumented posterolateral fusion versus non-instrumented anterior interbody fusion for lumbar spondylolisthesis: a prospective study with a 2-year follow-up

scientific article published on 13 May 2011

Spinal correction in patients with Fukuyama congenital muscular dystrophy

scientific article published on 18 March 2017

Spinal correction of scoliosis in Jeune syndrome: a report of two cases.

scientific article published on 2 March 2016

Spinal fusion on adolescent idiopathic scoliosis patients with the level of L4 or lower can increase lumbar disc degeneration with sagittal imbalance 35 years after surgery

scientific article published on 20 December 2017

Substance P-saporin down-regulates substance P receptor immunoreactive sensory dorsal root ganglion neurons innervating the lumbar intervertebral discs in rats

scientific article published on 01 December 2006

Surgical and nonsurgical treatments for lumbar spinal stenosis.

scientific article published on 25 July 2016

Surgical versus nonsurgical treatment of selected patients with discogenic low back pain: a small-sized randomized trial

scientific article published in March 2011

TNF-alpha in nucleus pulposus induces sensory nerve growth: a study of the mechanism of discogenic low back pain using TNF-alpha-deficient mice

scientific article published in June 2008

Teriparatide accelerates lumbar posterolateral fusion in women with postmenopausal osteoporosis: prospective study

scientific article

The cytokine expression in synovial membrane and the relationship with pain and pathological findings at hip arthroscopy

scientific article

The degenerated lumbar intervertebral disc is innervated primarily by peptide-containing sensory nerve fibers in humans

scientific article published on 01 October 2006

The effect of platelet-rich plasma on posterolateral lumbar fusion in a rat model

scientific article published in June 2013

The effects of risedronate and exercise on osteoporotic lumbar rat vertebrae and their sensory innervation

scientific article published on October 2010

The efficacy of nerve growth factor antibody in a mouse model of neuropathic cancer pain.

scientific article published on 17 May 2016

The hemopexin domain of matrix metalloproteinase-9 activates cell signaling and promotes migration of schwann cells by binding to low-density lipoprotein receptor-related protein

scientific article published on November 2008

The p75 receptor is associated with inflammatory thermal hypersensitivity

scientific article published on 01 December 2008

The prevalence and characteristics of low back pain among sitting workers in a Japanese manufacturing company

scientific article published on 8 September 2014

Transdermal fentanyl for chronic low back pain

scientific article

Transient receptor potential vanilloid 1-immunoreactive innervation increases in fractured rat femur

scientific article published on January 2014

Tumor necrosis factor-alpha in the nucleus pulposus mediates radicular pain, but not increase of inflammatory peptide, associated with nerve damage in mice

scientific article published on 01 August 2008

Tumor necrosis factor-immunoreactive cells and PGP 9.5-immunoreactive nerve fibers in vertebral endplates of patients with discogenic low back Pain and Modic Type 1 or Type 2 changes on MRI

scientific article published on 01 April 2006

Tumor necrosis factor-α-immunoreactive cells in nucleus pulposus in adolescent patients with lumbar disc herniation

scientific article published in March 2013

Uni- and bilateral instrumented posterolateral fusion of the lumbar spine with local bone grafting: a prospective study with a 2-year follow-up

scientific article published in December 2011

Up-Regulation of Pain Behavior and Glial Activity in the Spinal Cord after Compression and Application of Nucleus Pulposus onto the Sciatic Nerve in Rats

scientific article

Up-regulation of acid-sensing ion channel 3 in dorsal root ganglion neurons following application of nucleus pulposus on nerve root in rats

scientific article published in August 2006

Up-regulation of p55 TNF alpha-receptor in dorsal root ganglia neurons following lumbar facet joint injury in rats

scientific article

Upregulation of NaV1.7 in dorsal root ganglia after intervertebral disc injury in rats

scientific article published on 01 April 2014

Vascular Endothelial Growth Factor Is Regulated by the Canonical and Noncanonical Transforming Growth Factor-β Pathway in Synovial Fibroblasts Derived from Osteoarthritis Patients

scientific article published on 29 September 2019

Vertebral compression exacerbates osteoporotic pain in an ovariectomy-induced osteoporosis rat model

scientific article published in November 2013

Paulina is supported by:

About Paulina

Help