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List of works by Claudio Costantini

A Reappraisal of Thymosin Alpha1 in Cancer Therapy

scientific article published on 06 September 2019

A TrkA-to-p75NTR molecular switch activates amyloid beta-peptide generation during aging

scientific article published on October 2005

A reversible form of lysine acetylation in the ER and Golgi lumen controls the molecular stabilization of BACE1.

scientific article published on November 2007

A systems genomics approach identifies SIGLEC15 as a susceptibility factor in recurrent vulvovaginal candidiasis

scientific article published on 01 June 2019

An aging pathway controls the TrkA to p75NTR receptor switch and amyloid beta-peptide generation

scientific article

Anti-Müllerian hormone and antral follicle count reveal a late impairment of ovarian reserve in patients undergoing low-gonadotoxic regimens for hematological malignancies

scientific article published on 22 October 2013

Astrocytes regulate the expression of insulin-like growth factor 1 receptor (IGF1-R) in primary cortical neurons during in vitro senescence

scientific journal article

Autophagy and LAP in the Fight against Fungal Infections: Regulation and Therapeutics.

scientific article

Cellular proteostasis: a new twist in the action of thymosin α1

scientific article published on 01 July 2018

Ceramide and cholesterol: possible connections between normal aging of the brain and Alzheimer's disease. Just hypotheses or molecular pathways to be identified?

scientific article published in July 2005

Characterization of the signaling pathway downstream p75 neurotrophin receptor involved in beta-amyloid peptide-dependent cell death.

scientific article

Chronic graft versus host disease is associated with erectile dysfunction in allogeneic hematopoietic stem cell transplant patients: a single-center experience

scientific article published on 21 March 2018

Covid-19-Associated Pulmonary Aspergillosis: The Other Side of the Coin

scientific article published on 01 December 2020

Egr-1 and Hipk2 are required for the TrkA to p75(NTR) switch that occurs downstream of IGF1-R.

scientific article

Epigenetic Mechanisms of Inflammasome Regulation

scientific article published on 11 August 2020

Evidence for a cross-talk between human neutrophils and Th17 cells

article

Genetic Polymorphisms Affecting IDO1 or IDO2 Activity Differently Associate With Aspergillosis in Humans

scientific article published on 07 May 2019

Haploidentical hematopoietic stem cell transplantation in a myelofibrosis patient with primary graft failure

scientific article published in December 2017

Human neutrophils interact with both 6-sulfo LacNAc+ DC and NK cells to amplify NK-derived IFN{gamma}: role of CD18, ICAM-1, and ICAM-3.

scientific article published on 22 November 2010

IFN-β expression is directly activated in human neutrophils transfected with plasmid DNA and is further increased via TLR-4-mediated signaling.

scientific article published on 22 June 2012

IL-9 Integrates the Host- Cross-Talk in Vulvovaginal Candidiasis to Balance Inflammation and Tolerance

scientific article published on 20 November 2018

IL-9 and Mast Cells Are Key Players of Candida albicans Commensalism and Pathogenesis in the Gut.

scientific article

Indole-3-Carboxaldehyde Restores Gut Mucosal Integrity and Protects from Liver Fibrosis in Murine Sclerosing Cholangitis

scientific article published on 29 June 2021

Neutrophil activation and survival are modulated by interaction with NK cells.

scientific article published on 25 August 2010

Neutrophils promote 6-sulfo LacNAc+ dendritic cell (slanDC) survival

scientific article published on 4 April 2013

On the co-purification of 6-sulfo LacNAc(+) dendritic cells (slanDC) with NK cells enriched from human blood

scientific article

On the potential involvement of CD11d in co-stimulating the production of interferon-γ by natural killer cells upon interaction with neutrophils via intercellular adhesion molecule-3.

scientific article

Optimizing therapeutic outcomes of immune checkpoint blockade by a microbial tryptophan metabolite

scientific article published on 01 March 2022

PCSK9 is required for the disposal of non-acetylated intermediates of the nascent membrane protein BACE1.

scientific article published on 25 July 2008

Pyridoxal 5'-Phosphate-Dependent Enzymes at the Crossroads of Host-Microbe Tryptophan Metabolism

scientific article published on 13 August 2020

Rapid reconstitution of functionally active 6-sulfoLacNAc(+) dendritic cells (slanDCs) of donor origin following allogeneic haematopoietic stem cell transplant

scientific article published on 01 October 2014

Relationship between testicular sperm extraction and varicocelectomy in patients with varicocele and nonobstructive azoospermia

scientific article

Reply to ‘F508del-CFTR is not corrected by thymosin α1’

scientific article published on 01 July 2018

Small Molecule CCR4 Antagonists Protect Mice from Aspergillus Infection and Allergy

scientific article published in 2021

Targeted Drug Delivery Technologies Potentiate the Overall Therapeutic Efficacy of an Indole Derivative in a Mouse Cystic Fibrosis Setting

scientific article published on 28 June 2021

Targeting the Aryl Hydrocarbon Receptor With Indole-3-Aldehyde Protects From Vulvovaginal Candidiasis via the IL-22-IL-18 Cross-Talk

scientific article published on 11 October 2019

The IL-17F/IL-17RC Axis Promotes Respiratory Allergy in the Proximal Airways

scientific article published on August 2017

The ILE56 mutation on different genetic backgrounds of alanine: Glyoxylate aminotransferase: Clinical features and biochemical characterization

scientific article published on 07 August 2020

The Mast Cell-Aryl Hydrocarbon Receptor Interplay at the Host-Microbe Interface.

scientific article published on 28 October 2018

The Microbiota/Host Immune System Interaction in the Nose to Protect from COVID-19

scientific article published on 11 December 2020

The defensive alliance between neutrophils and NK cells as a novel arm of innate immunity.

scientific article published on 03 August 2010

The expression of p75 neurotrophin receptor protects against the neurotoxicity of soluble oligomers of beta-amyloid

scientific article published on 11 October 2005

Thymosin α1 protects from CTLA-4 intestinal immunopathology

scientific article published on 14 August 2020

Thymosin β4 limits inflammation through autophagy

scientific article published on 01 July 2018

Thymosin β4 promotes autophagy and repair via HIF-1α stabilization in chronic granulomatous disease

scientific article published on 12 November 2019

Tryptophan as a Central Hub for Host/Microbial Symbiosis

scientific article published on 11 May 2020

slanDCs selectively accumulate in carcinoma-draining lymph nodes and marginate metastatic cells

scientific article published in Nature Communications