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List of works by Jasper E Neggers

Down-regulation of AR splice variants through XPO1 suppression contributes to the inhibition of prostate cancer progression

scientific article published on 19 October 2018

Heterozygous mutation of cysteine528 in XPO1 is sufficient for resistance to selective inhibitors of nuclear export

scientific article published on 13 September 2016

Human Exportin-1 is a Target for Combined Therapy of HIV and AIDS Related Lymphoma

scientific article

Identifying drug-target selectivity of small-molecule CRM1/XPO1 inhibitors by CRISPR/Cas9 genome editing

scientific article published on 8 January 2015

Preclinical Assessment with Clinical Validation of Selinexor with Gemcitabine and Nab-Paclitaxel for the Treatment of Pancreatic Ductal Adenocarcinoma

scientific article published on 12 December 2019

Target identification of small molecules using large-scale CRISPR-Cas mutagenesis scanning of essential genes

scientific article

The Second-Generation Exportin-1 Inhibitor KPT-8602 Demonstrates Potent Activity against Acute Lymphoblastic Leukemia.

scientific article

XPO1-dependent nuclear export is a druggable vulnerability in KRAS-mutant lung cancer.

scientific article published on 28 September 2016

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