List of works by Ramon Bartrons

6-Phosphofructo-2-kinase (pfkfb3) gene promoter contains hypoxia-inducible factor-1 binding sites necessary for transactivation in response to hypoxia

scientific article

6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase expression in rat brain during development

scientific journal article

Activation of AMP-dependent protein kinase by hypoxia and hypothermia in the liver of frog Rana perezi

scientific article published on 01 October 2004

Addition of adenosine monophosphate-activated protein kinase activators to University of Wisconsin solution: A way of protecting rat steatotic livers

scientific article published on 01 March 2007

Adenosine monophosphate-activated protein kinase and nitric oxide in rat steatotic liver transplantation

scientific article published on 27 June 2005

Akt mediates TIGAR induction in HeLa cells following PFKFB3 inhibition.

scientific article published on 4 August 2016

Akt-dependent activation of the heart 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB2) isoenzyme by amino acids.

scientific article published on 2 March 2013

Amino acids activate mammalian target of rapamycin complex 2 (mTORC2) via PI3K/Akt signaling

scientific article

Analysis of Protein Oligomerization by Electrophoresis.

scientific article published in January 2016

Antiproliferative effect of catechin in GRX cells.

scientific article

Assessment of a dual regulatory role for NO in liver regeneration after partial hepatectomy: protection against apoptosis and retardation of hepatocyte proliferation

scientific article published on 23 March 2005

BMP-2 decreases Mash1 stability by increasing Id1 expression

scientific article

BMP2 induction of actin cytoskeleton reorganization and cell migration requires PI3-kinase and Cdc42 activity.

scientific article published on 11 November 2008

CPEB4 Increases Expression of PFKFB3 to Induce Glycolysis and Activate Mouse and Human Hepatic Stellate Cells, Promoting Liver Fibrosis

scientific article published on 10 March 2020

Capsaicin modulates proliferation, migration, and activation of hepatic stellate cells.

scientific article published on March 2014

Cerebrospinal dopamine metabolites in rats after intrastriatal administration of 6-hydroxydopamine or 1-methyl-4-phenylpyridinium ion

scientific article published on 01 January 1995

Cerebrospinal monoamine metabolites and amino acid content in patients with parkinsonian syndrome and rats lesioned with MPP+

scientific article published on 01 January 1994

Characterization of a new liver- and kidney-specific pfkfb3 isozyme that is downregulated by cell proliferation and dedifferentiation.

scientific article

Cloning and expression of a catalytic core bovine brain 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.

scientific article published on April 1995

Cloning, expression and chromosomal localization of a human testis 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene

scientific article

Conserved regulatory motifs in osteogenic gene promoters integrate cooperative effects of canonical Wnt and BMP pathways.

scientific article published on April 2011

Contribution of S6K1/MAPK signaling pathways in the response to oxidative stress: activation of RSK and MSK by hydrogen peroxide

scientific article

Cooperation of adenosine with macrophage Toll-4 receptor agonists leads to increased glycolytic flux through the enhanced expression of PFKFB3 gene.

scientific article published on 4 April 2011

Copolymers of poly-L-lysine with serine and tryptophan form stable DNA vectors: implications for receptor-mediated gene transfer.

scientific article

Correction: Contribution of S6K1/MAPK Signaling Pathways in the Response to Oxidative Stress: Activation of RSK and MSK by Hydrogen Peroxide

scholarly article published in PLOS ONE

Corrigendum to "ERK and p38 pathways regulate amino acid signalling" [BBA-Mol. Cell. Res. Volume 1783/12 (2008) 2241-2254]

scientific article published on 25 June 2019

Detection of mRNA encoding H(1) receptor and iNOS by RT-PCR in autoimmune myocarditis with special reference to changes in heart contractility

scientific article published on 01 November 2000

ERK and p38 pathways regulate amino acid signalling

scientific article published on 6 September 2008

Early effects of basic fibroblast growth factor on foetal rat mesencephalic cell suspensions

scientific article published in December 1996

Editorial: Cancer Ecosystems

scientific article published on 20 August 2019

Effect of TPA on fructose 2,6-bisphosphate levels and protein kinase C activity in B-chronic lymphocytic leukemia (B-CLL)

scientific article published in November 1991

Effect of different preservation solutions on adenine nucleotide content and metabolism in human kidney transplantation

scientific article published on 01 January 1994

Effect of galactosamine on hepatic carbohydrate metabolism: protective role of fructose 1,6-bisphosphate

scientific article published on 01 June 1992

Fructose 2,6-Bisphosphate in Cancer Cell Metabolism

scientific article published on 04 September 2018

Fructose 2,6-bisphosphate in developing rat brain

scientific article published in April 1992

Fructose-1,6-bisphosphate inhibits the expression of inducible nitric oxide synthase caused by oxygen-glucose deprivation through the inhibition of glutamate release in rat forebrain slices

scientific article published on 01 September 2000

Fructose-1,6-bisphosphate protects against Zymosan-induced acute lung injury in mice

scientific article published on 01 June 2012

Fructose-1,6-bisphosphate reduces the mortality in Candida albicans bloodstream infection and prevents the septic-induced platelet decrease

scientific article published on 01 August 2012

Growth Hormone Inhibits Hepatic De Novo Lipogenesis in Adult Mice

scientific article

HIF-1α and PFKFB3 Mediate a Tight Relationship Between Proinflammatory Activation and Anerobic Metabolism in Atherosclerotic Macrophages

scientific article published on 16 April 2015

HPLC analysis of hexosamine phosphates in biological samples

scientific article published on December 1, 1992

Heat shock proteins and mitogen-activated protein kinases in steatotic livers undergoing ischemia-reperfusion: some answers.

scientific article published on May 2006

How ischaemic preconditioning protects small liver grafts

scientific article published on 01 January 2006

Hypoxia inducible factor-1alpha accumulation in steatotic liver preservation: role of nitric oxide.

scientific article

Hypoxia, glucose metabolism and the Warburg's effect.

scientific article published on June 2007

Insulin induces PFKFB3 gene expression in HT29 human colon adenocarcinoma cells

scientific article

Interaction between HERC1 and M2-type pyruvate kinase

scientific article

Isolation and characterization of phosphofructo 2-kinase from chicken erythrocytes

scientific article published on 01 January 1990

Large HERCs Function as Tumor Suppressors

scientific article published on 18 June 2019

Leucine reduces the proliferation of MC3T3-E1 cells through DNA damage and cell senescence.

scientific article

Liver CPT1A gene therapy reduces diet-induced hepatic steatosis in mice and highlights potential lipid biomarkers for human NAFLD

scientific article published on 15 July 2020

Liver Glucokinase(A456V) Induces Potent Hypoglycemia without Dyslipidemia through a Paradoxical Induction of the Catalytic Subunit of Glucose-6-Phosphatase

scientific article

MPP+ toxicity in rat striatal slices: relationship between non-selective effects and free radical production

scientific article published on 01 January 1996

Matrix metalloproteinase 2 in reduced-size liver transplantation: beyond the matrix

scientific article

Mediators of rat ischemic hepatic preconditioning after cold preservation identified by microarray analysis.

scientific article

MicroRNA-322 (miR-322) and its target protein Tob2 modulate Osterix (Osx) mRNA stability

scientific article published on 5 April 2013

Modulation of inflammatory response and parasitism by 15-Deoxy-Δ(12,14) prostaglandin J(2) in Trypanosoma cruzi-infected cardiomyocytes

article

NEURL4 regulates the transcriptional activity of tumor suppressor protein p53 by modulating its oligomerization.

scientific article published on 27 June 2017

Neuregulin improves response to glucose tolerance test in control and diabetic rats.

scientific article

Nitric oxide inhibits DNA synthesis and induces activation of poly(ADP-ribose) polymerase in cultured rat hepatocytes

scientific article published on 01 October 1996

Noncanonical BMP signaling regulates cyclooxygenase-2 transcription.

scientific article published on 24 March 2011

Oral administration of vanadate to diabetic rats restores liver 6-phosphofructo-2-kinase content and mRNA

scientific article published on 01 March 1992

Overcoming diabetes-induced hyperglycemia through inhibition of hepatic phosphoenolpyruvate carboxykinase (GTP) with RNAi.

scientific article published on 3 November 2005

Overexpression of ubiquitous 6-phosphofructo-2-kinase in the liver of transgenic mice results in weight gain.

scientific article published on 6 November 2007

PFK-2/FBPase-2: maker and breaker of the essential biofactor fructose-2,6-bisphosphate.

scientific article

PFKFB3 activation in cancer cells by the p38/MK2 pathway in response to stress stimuli

scientific article

PFKFB3 gene silencing decreases glycolysis, induces cell-cycle delay and inhibits anchorage-independent growth in HeLa cells

scientific article

PGC-1α Downregulation in Steatotic Liver Enhances Ischemia-Reperfusion Injury and Impairs Ischemic Preconditioning.

scientific article published on 7 March 2017

PI3K-Akt signaling controls PFKFB3 expression during human T-lymphocyte activation.

scientific article published on 12 February 2018

Pck1 gene silencing in the liver improves glycemia control, insulin sensitivity, and dyslipidemia in db/db mice.

scientific article published on 28 April 2008

Pfkfb3 is transcriptionally upregulated in diabetic mouse liver through proliferative signals.

scientific article published on 18 July 2009

Progestins activate 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) in breast cancer cells

scientific article

Protective effect of nifedipine against carrageenan-induced inflammation

scientific article published on 01 March 1998

Regulation of the MDM2-p53 pathway by the ubiquitin ligase HERC2

scientific article published on 15 November 2019

Regulation of ubiquitous 6-phosphofructo-2-kinase by the ubiquitin-proteasome proteolytic pathway during myogenic C2C12 cell differentiation

scientific article (publication date: 28 August 2003)

Repression of SOX6 transcriptional activity by SUMO modification

scientific article

Requirement of phosphatidylinositol-4,5-bisphosphate for HERC1-mediated guanine nucleotide release from ARF proteins

scientific article

Role of Akt/PKB and PFKFB isoenzymes in the control of glycolysis, cell proliferation and protein synthesis in mitogen-stimulated thymocytes

scientific article published on 21 February 2017

Role of PFKFB3-driven glycolysis in vessel sprouting

scientific article

Sertoli-secreted FGF-2 induces PFKFB4 isozyme expression in mouse spermatogenic cells by activation of the MEK/ERK/CREB pathway.

scientific article

Simultaneous electrophoretic analysis of proteins of very high and low molecular mass using Tris-acetate polyacrylamide gels.

scientific article published on April 2010

Simultaneous electrophoretic analysis of proteins of very high and low molecular weights using low-percentage acrylamide gel and a gradient SDS-PAGE gel.

scientific article published in October 2006

Single-stranded DNA condensed with poly-L-lysine results in nanometric particles that are significantly smaller, more stable in physiological ionic strength fluids and afford higher efficiency of gene delivery than their double-stranded counterparts

scientific article published on 01 August 2002

Specific expression of pfkfb4 gene in spermatogonia germ cells and analysis of its 5'-flanking region.

scientific article

Stereotaxic administration of 1-methyl-4-phenylpyridinium ion (MPP+) decreases striatal fructose 2,6-bisphosphate in rats

scientific article published in May 1994

Stimulators of AMP-activated protein kinase inhibit the respiratory burst in human neutrophils.

scientific article

Switches in 6-phosphofructo-2-kinase isoenzyme expression during rat sperm maturation

scientific article published on 10 July 2009

TGF-β1 targets Smad, p38 MAPK, and PI3K/Akt signaling pathways to induce PFKFB3 gene expression and glycolysis in glioblastoma cells

scientific article published on 20 August 2017

TIGAR, a p53-inducible regulator of glycolysis and apoptosis

scientific journal article

TP53 induced glycolysis and apoptosis regulator (TIGAR) knockdown results in radiosensitization of glioma cells.

scientific article

TP53-inducible Glycolysis and Apoptosis Regulator (TIGAR) Metabolically Reprograms Carcinoma and Stromal Cells in Breast Cancer

scientific article published in November 2016

The E3 ubiquitin ligase HERC1 controls the ERK signaling pathway targeting C-RAF for degradation

scientific article published on 31 July 2018

The E3 ubiquitin protein ligase HERC2 modulates the activity of tumor protein p53 by regulating its oligomerization

scientific article published on 9 April 2014

The HERC2 ubiquitin ligase is essential for embryonic development and regulates motor coordination.

scientific article published on 12 August 2016

The combination of ischemic preconditioning and liver Bcl-2 overexpression is a suitable strategy to prevent liver and lung damage after hepatic ischemia-reperfusion

scientific article published on June 2002

The giant protein HERC1 is recruited to aluminum fluoride-induced actin-rich surface protrusions in HeLa cells.

scientific article

The human ubiquitous 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene (PFKFB3): promoter characterization and genomic structure

scientific article (publication date: 7 February 2001)

The potential utility of PFKFB3 as a therapeutic target

scientific article published on 16 July 2018

The stimulation of yeast phosphofructokinase by fructose 2,6-bisphosphate ⬇️

scientific article published on June 21, 1982

The transcriptional activation of the cyclooxygenase-2 gene in zymosan-activated macrophages is dependent on NF-kappa B, C/EBP, AP-1, and CRE sites

scientific article published on December 2011

The ubiquitin ligase HERC1 regulates cell migration via RAF-dependent regulation of MKK3/p38 signaling

scientific article published on 21 January 2020

The use of a reversible proteasome inhibitor in a model of Reduced-Size Orthotopic Liver transplantation in rats

scientific article published on 25 March 2012

Therapeutic ultrasound stimulates MC3T3-E1 cell proliferation through the activation of NF-κB1, p38α, and mTOR.

scientific article published on 28 September 2015

Tris-Acetate Polyacrylamide Gradient Gels for the Simultaneous Electrophoretic Analysis of Proteins of Very High and Low Molecular Mass

scientific article published on 01 January 2019

Tris-acetate polyacrylamide gradient gel electrophoresis for the analysis of protein oligomerization.

scientific article published on 11 January 2016

Tris-acetate polyacrylamide gradient gels for the simultaneous electrophoretic analysis of proteins of very high and low molecular mass

scientific article published in January 2012

Ubiquitin-proteasome system inhibitors and AMPK regulation in hepatic cold ischaemia and reperfusion injury: possible mechanisms

scientific article published on July 2012

Vanadate inhibits liver fructose-2,6-bisphosphatase

scientific article published on 01 May 1990

p38 regulates expression of osteoblast-specific genes by phosphorylation of osterix

scientific article published on 3 August 2010

p38gamma MAPK is essential for aerobic glycolysis and pancreatic tumorigenesis

scientific article published on 24 June 2020

p38α function in osteoblasts influences adipose tissue homeostasis.

scientific article published on 30 December 2014

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