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List of works by Hiroshi Tazawa

A Novel Combination Cancer Therapy with Iron Chelator Targeting Cancer Stem Cells via Suppressing Stemness

scientific article published on 03 February 2019

A genetically engineered oncolytic adenovirus decoys and lethally traps quiescent cancer stem-like cells in S/G2/M phases.

scientific article published on 30 September 2013

A protein transduction method using oligo-arginine (3R) for the delivery of transcription factors into cell nuclei.

scientific article

A simple biological imaging system for detecting viable human circulating tumor cells

scientific article

A simple detection system for adenovirus receptor expression using a telomerase-specific replication-competent adenovirus.

scientific article published on 12 January 2012

Advances in adenovirus-mediated p53 cancer gene therapy

scientific article

Anti-high mobility group box 1 monoclonal antibody improves ischemia/reperfusion injury and mode of liver regeneration after partial hepatectomy

scientific article published on 3 September 2015

Biological ablation of sentinel lymph node metastasis in submucosally invaded early gastrointestinal cancer

scientific article

Bone and Soft-Tissue Sarcoma: A New Target for Telomerase-Specific Oncolytic Virotherapy

scientific article published on 18 February 2020

Cancer cells mimic in vivo spatial-temporal cell-cycle phase distribution and chemosensitivity in 3-dimensional Gelfoam® histoculture but not 2-dimensional culture as visualized with real-time FUCCI imaging.

scientific article

Chronic inflammation-derived nitric oxide causes conversion of human colonic adenoma cells into adenocarcinoma cells

scientific article published on 13 August 2013

Dual programmed cell death pathways induced by p53 transactivation overcome resistance to oncolytic adenovirus in human osteosarcoma cells

scientific article published on 11 January 2013

Establishment of a Non-Invasive Semi-Quantitative Bioluminescent Imaging Method for Monitoring of an Orthotopic Esophageal Cancer Mouse Model

scientific article (publication date: 2014)

Establishment of a pancreatic stem cell line from fibroblast-derived induced pluripotent stem cells.

scientific article

FUCCI Real-Time Cell-Cycle Imaging as a Guide for Designing Improved Cancer Therapy: A Review of Innovative Strategies to Target Quiescent Chemo-Resistant Cancer Cells

scientific article published on 17 September 2020

Fascin regulates chronic inflammation-related human colon carcinogenesis by inhibiting cell anoikis

scientific article published on 25 March 2014

Fluorescence virus-guided capturing system of human colorectal circulating tumour cells for non-invasive companion diagnostics.

scientific article

Genetically engineered oncolytic adenovirus induces autophagic cell death through an E2F1-microRNA-7-epidermal growth factor receptor axis.

scientific article published on 30 April 2012

Immuno-hyperthermia effected by antibody-conjugated nanoparticles selectively targets and eradicates individual cancer cells

scientific article published on 19 June 2021

Impact of Autophagy in Oncolytic Adenoviral Therapy for Cancer

scientific article

In vivo biological purging for lymph node metastasis of human colorectal cancer by telomerase-specific oncolytic virotherapy

scientific article published in June 2010

Increased risk of intestinal type of gastric adenocarcinoma in Japanese women associated with long forms of CCTTT pentanucleotide repeat in the inducible nitric oxide synthase promoter

scientific article published on 01 January 2005

Integrated fluorescent cytology with nano-biologics in peritoneally disseminated gastric cancer

scientific article published on 23 September 2018

Intraperitoneal cancer-immune microenvironment promotes peritoneal dissemination of gastric cancer

scientific article published on 22 October 2019

Invading cancer cells are predominantly in G0/G1 resulting in chemoresistance demonstrated by real-time FUCCI imaging

scientific article

Involvement of reactive nitrogen oxides for acquisition of metastatic properties of benign tumors in a model of inflammation-based tumor progression

scientific article published on 5 October 2005

Liposome-encapsulated plasmid DNA of telomerase-specific oncolytic adenovirus with stealth effect on the immune system

scientific article published on 26 October 2017

Loss of p53 in stromal fibroblasts enhances tumor cell proliferation through nitric-oxide-mediated cyclooxygenase 2 activation

scientific article published on 9 February 2015

Mechanism of resistance to trastuzumab and molecular sensitization via ADCC activation by exogenous expression of HER2-extracellular domain in human cancer cells ⬇️

scientific article published on March 31, 2012

MicroRNAs as potential target gene in cancer gene therapy of gastrointestinal tumors ⬇️

scientific article published on February 1, 2011

Molecular diagnosis and therapy for occult peritoneal metastasis in gastric cancer patients

scientific article

Mouse strain differences in inflammatory responses of colonic mucosa induced by dextran sulfate sodium cause differential susceptibility to PhIP-induced large bowel carcinogenesis

scientific article published on 15 June 2007

Oxidative and nitrative stress caused by subcutaneous implantation of a foreign body accelerates sarcoma development in Trp53+/- mice

scientific article published on 20 July 2006

PD-L1 expression combined with microsatellite instability/CD8+ tumor infiltrating lymphocytes as a useful prognostic biomarker in gastric cancer

scientific article published on 15 March 2019

Preclinical evaluation of telomerase-specific oncolytic virotherapy for human bone and soft tissue sarcomas.

scientific article published on 16 February 2011

Role of zoledronic acid in oncolytic virotherapy: Promotion of antitumor effect and prevention of bone destruction

scientific article published on 7 July 2017

Spatial-temporal FUCCI imaging of each cell in a tumor demonstrates locational dependence of cell cycle dynamics and chemoresponsiveness

scientific article

Suppression of thymic lymphomas and increased nonthymic lymphomagenesis in Trp53-deficient mice lacking inducible nitric oxide synthase gene.

scientific article

Telomerase-specific oncolytic immunotherapy for promoting efficacy of PD-1 blockade in osteosarcoma

scientific article published on 05 November 2020

The role of nicotinamide adenine dinucleotide phosphate oxidase-derived reactive oxygen species in the acquisition of metastatic ability of tumor cells

scientific article

Tumor-targeting Salmonella typhimurium A1-R decoys quiescent cancer cells to cycle as visualized by FUCCI imaging and become sensitive to chemotherapy

scientific article

Viral transduction of the HER2-extracellular domain expands trastuzumab-based photoimmunotherapy for HER2-negative breast cancer cells

scientific article published on 24 January 2015

Visualization of epithelial-mesenchymal transition in an inflammatory microenvironment-colorectal cancer network

scientific article published on 08 November 2019

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