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List of works by Irina Stepanov

"Cold turkey" or pharmacotherapy: Examination of tobacco cessation methods tried among smokers prior to developing head and neck cancer

scientific article published on 15 February 2019

A Randomized Clinical Trial of Snus Examining the Effect of Complete Versus Partial Cigarette Substitution on Smoking-Related Behaviors, and Biomarkers of Exposure

scientific article published on 01 April 2020

Abuse liability assessment of an e-cigarette refill liquid using intracranial self-stimulation and self-administration models in rats.

scientific article published in September 2016

Analysis of 23 polycyclic aromatic hydrocarbons in smokeless tobacco by gas chromatography-mass spectrometry

scientific article published on January 2010

Analysis of 4-Hydroxy-1-(3-pyridyl)-1-butanone (HPB)-Releasing DNA Adducts in Human Exfoliated Oral Mucosa Cells by Liquid Chromatography–Electrospray Ionization–Tandem Mass Spectrometry ⬇️

scientific article published on January 10, 2013

Analysis of Alkaloids in Areca Nut-Containing Products by Liquid Chromatography-Tandem Mass Spectrometry

scientific article published on 13 February 2017

Analysis of a malondialdehyde-deoxyguanosine adduct in human leukocyte DNA by liquid chromatography nanoelectrospray-high-resolution tandem mass spectrometry.

scientific article

Analysis of tobacco-specific nitrosamines in Moldovan cigarette tobacco

scientific article published in May 2002

Animal models to assess the abuse liability of tobacco products: effects of smokeless tobacco extracts on intracranial self-stimulation.

scientific article

Assessing Constituent Levels in Smokeless Tobacco Products: A New Approach to Engaging and Educating the Public

scientific article

Bringing attention to e-cigarette pH as an important element for research and regulation: Table 1

scientific article published on 14 May 2014

Carcinogenic tobacco-specific N-nitrosamines in US cigarettes: three decades of remarkable neglect by the tobacco industry

scientific article published on 20 May 2011

Cigarette Design Features: Effects on Emission Levels, User Perception, and Behavior.

scientific article published in January 2018

Cigarette Smokers vs. Co-users of Cannabis and Cigarettes: Exposure to Toxicants

scientific article published on 16 October 2019

Cigarette and e-liquid demand and substitution in e-cigarette-naïve smokers

scientific article published on 01 June 2018

Comparative Analysis of Tobacco-Specific Nitrosamines and TotalN-Nitroso Compounds in Moldovan Cigarette Tobacco

scientific article published on 01 October 2005

Comprehensive High-Resolution Mass Spectrometric Analysis of DNA Phosphate Adducts Formed by the Tobacco-Specific Lung Carcinogen 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone.

scientific article

Consortium on Methods Evaluating Tobacco: Research Tools to Inform FDA Regulation of Snus.

scientific article published on 4 October 2017

Delivery of nicotine in an extract of a smokeless tobacco product reduces its reinforcement-attenuating and discriminative stimulus effects in rats

scientific article

Detection and quantitation of N'-nitrosonornicotine in human toenails by liquid chromatography-electrospray ionization-tandem mass spectrometry.

scientific article published on April 2008

Effect of oral snus and medicinal nicotine in smokers on toxicant exposure and withdrawal symptoms: a feasibility study

scientific article

Effective Message Elements for Disclosures about Chemicals in Cigarette Smoke.

scientific article published on 17 May 2017

Effects of nicotine-containing and "nicotine-free" e-cigarette refill liquids on intracranial self-stimulation in rats

scientific article published in February 2018

Elevated levels of 1-hydroxypyrene and N'-nitrosonornicotine in smokers with head and neck cancer: A matched control study

scientific article published on 17 July 2012

Endogenous formation of N'-nitrosonornicotine in F344 rats in the presence of some antioxidants and grape seed extract

scientific article published on 19 July 2007

Evidence for endogenous formation of N'-nitrosonornicotine in some long-term nicotine patch users.

scientific article published on 27 January 2009

Evidence supporting product standards for carcinogens in smokeless tobacco products

scientific article

Exposure and Metabolic Activation Biomarkers of Carcinogenic Tobacco-Specific Nitrosamines.

scientific article published on 17 December 2015

Genome-wide mapping of 8-oxo-7,8-dihydro-2'-deoxyguanosine reveals accumulation of oxidatively-generated damage at DNA replication origins within transcribed long genes of mammalian cells

article

Have combustible cigarettes met their match? The nicotine delivery profiles and harmful constituent exposures of second-generation and third-generation electronic cigarette users

scientific article published on 11 October 2016

Heated tobacco products: things we do and do not know

scientific article

High Level of Tobacco Carcinogen-Derived DNA Damage in Oral Cells Is an Independent Predictor of Oral/Head and Neck Cancer Risk in Smokers.

scientific article published on 5 July 2017

High levels of tobacco-specific N-nitrosamines and nicotine in Chaini Khaini, a product marketed as snus

scientific article

How people think about the chemicals in cigarette smoke: a systematic review.

scientific article published on 21 February 2017

Identification of More Than One Hundred Structurally Unique DNA-Phosphate Adducts Formed During Rat Lung Carcinogenesis by the Tobacco-Specific Nitrosamine 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone.

scientific article published on 29 November 2017

Increased pouch sizes and resulting changes in the amounts of nicotine and tobacco-specific N-nitrosamines in single pouches of Camel Snus and Marlboro Snus.

scientific article

Influence of UGT2B10 genotype on urinary excretion of NNAL-N-glucuronide by African American smokers.

scientific article published on 20 February 2018

Isotope Dilution nanoLC/ESI+-HRMS3 Quantitation of Urinary N7-(1-Hydroxy-3-buten-2-yl) Guanine Adducts in Humans and Their Use as Biomarkers of Exposure to 1,3-Butadiene

scientific article published on 20 December 2016

Levels of (S)-N'-nitrosonornicotine in U.S. tobacco products.

scientific article published on 03 December 2012

Liquid chromatography-electrospray ionization-tandem mass spectrometry quantitation of urinary [pyridine-D4]4-hydroxy-4-(3-pyridyl)butanoic acid, a biomarker of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolic activation in smokers

scientific article published on 25 August 2014

Major tobacco companies have technology to reduce carcinogen levels but do not apply it to popular smokeless tobacco products.

scientific article published on 07 October 2010

Mass Spectrometric Quantitation of Nicotine, Cotinine, and 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in Human Toenails

scientific article published on 01 December 2006

Measuring the impact of manganese exposure on children's neurodevelopment: advances and research gaps in biomarker-based approaches

journal article published in 2016

Metabolism of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone to its biomarker total NNAL in smokeless tobacco users

scientific article

Methyl DNA Phosphate Adduct Formation in Rats Treated Chronically with 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone and Enantiomers of Its Metabolite 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol

scientific article

Methyl DNA phosphate adduct formation in lung tumor tissue and adjacent normal tissue of lung cancer patients

scientific article published on 01 November 2019

Mitochondrial DNA adducts in the lung and liver of F344 rats chronically treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and (S)-4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol

scientific article published in February 2009

Monitoring Tobacco-Specific N-Nitrosamines and Nicotine in Novel Marlboro and Camel Smokeless Tobacco Products: Findings From Round 1 of the New Product Watch ⬇️

scientific article published on October 29, 2011

Monitoring tobacco-specific N-nitrosamines and nicotine in novel smokeless tobacco products: findings from round II of the new product watch

scientific article

New and traditional smokeless tobacco: comparison of toxicant and carcinogen levels.

scientific article

Non-nicotine constituents in e-cigarette aerosol extract attenuate nicotine's aversive effects in adolescent rats

scientific article published on 01 August 2019

Nornicotine nitrosation in saliva and its relation to endogenous synthesis of N'-nitrosonornicotine in humans.

scientific article

Optimized Liquid Chromatography Nanoelectrospray-High-Resolution Tandem Mass Spectrometry Method for the Analysis of 4-Hydroxy-1-(3-pyridyl)-1-butanone-Releasing DNA Adducts in Human Oral Cells

scientific article published on 13 September 2016

Oral Health Effects of Combusted and Smokeless Tobacco Products

scientific article published on 01 October 2019

Patterns of Tobacco Cessation Attempts and Symptoms Experienced Among Smokers With Head and Neck Squamous Cell Carcinoma

scientific article published on 01 June 2018

Point-of-Sale Tobacco Advertising Remains Prominent in Mumbai, India.

scientific article published on July 2016

Presence of the Carcinogen N'-Nitrosonornicotine in Saliva of E-cigarette Users

scientific article published on 30 July 2018

Presence of the carcinogen N'-nitrosonornicotine in the urine of some users of oral nicotine replacement therapy products

scientific article

Public education about the relative harm of tobacco products: an intervention for tobacco control professionals

scientific article

Pyridylhydroxybutyl and pyridyloxobutyl DNA phosphate adduct formation in rats treated chronically with enantiomers of the tobacco-specific nitrosamine metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.

scientific article published on 27 November 2017

Recent Studies on DNA Adducts Resulting from Human Exposure to Tobacco Smoke

article

Reduced nicotine content cigarettes: effects on toxicant exposure, dependence and cessation.

scientific article

Relationship of human toenail nicotine, cotinine, and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol to levels of these biomarkers in plasma and urine

scientific article published in July 2007

Self-reported Tobacco use does not correlate with carcinogen exposure in smokers with head and neck cancer

scientific article published on 15 April 2015

Simultaneous determination of 8-oxo-2'-deoxyguanosine and 8-oxo-2'-deoxyadenosine in human retinal DNA by liquid chromatography nanoelectrospray-tandem mass spectrometry

scientific article published on 16 March 2016

The Wild West of E-Cigarettes

scientific article published on 06 September 2018

Tobacco carcinogen research to aid understanding of cancer risk and influence policy

scientific article published on 03 October 2018

Tobacco smoke biomarkers and cancer risk among male smokers in the Shanghai cohort study

scientific article published on 20 July 2012

Tobacco-specific N-nitrosamine exposures and cancer risk in the Shanghai Cohort Study: remarkable coherence with rat tumor sites

scientific article

Tobacco-specific nitrosamines and their pyridine-N-glucuronides in the urine of smokers and smokeless tobacco users

scientific article published in April 2005

Tobacco-specific nitrosamines in smokeless tobacco products marketed in India

scientific article

Tobacco‐specific nitrosamines in new tobacco products

scientific article published on 01 April 2006

Toenail manganese as a potential biomarker for in utero and early childhood exposure studies

journal article published in 2018

Uptake of the tobacco-specific lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by Moldovan children.

scientific article

Urinary levels of the tobacco-specific carcinogen N'-nitrosonornicotine and its glucuronide are strongly associated with esophageal cancer risk in smokers.

scientific article

Urinary tobacco smoke-constituent biomarkers for assessing risk of lung cancer

scientific article

Variations of toxic and carcinogenic constituents in nasvai: call for systematic research and regulation

scientific article

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