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List of works by Enzo Martegani

3-Nitrocoumarin is an efficient inhibitor of budding yeast phospholipase-C.

scientific article published in December 2001

A bimolecular mechanism for the cell size control of the cell cycle

scientific article published in January 1983

A computer algorithm for the analysis of protein distribution in budding yeast.

scientific article published in January 1984

A double flow cytometric tag allows tracking of the dynamics of cell cycle progression of newborn Saccharomyces cerevisiae cells during balanced exponential growth

scientific article published in September 1995

A mouse CDC25-like product enhances the formation of the active GTP complex of human ras p21 and Saccharomyces cerevisiae RAS2 proteins

scientific article published on 01 December 1992

A new nerve growth factor-mimetic peptide active on neuropathic pain in rats

scientific article published in March 2008

Activation of amyloid precursor protein processing by growth factors is dependent on Ras GTPase activity.

scientific article published on 15 December 2010

Activation state of the Ras2 protein and glucose-induced signaling in Saccharomyces cerevisiae.

scientific article

Alteration of cell population structure due to cell lysis inSaccharomyces cerevisiae cells overexpressing theGAL4 gene

article

Analysis of a model of cell cycle in eukaryotes

scientific article published on 01 November 1980

Analysis of protein and cell volume distribution in glucose-limited continuous cultures of budding yeast

scientific article published in February 1986

Analysis of protein distribution in budding yeast

scientific article published in May 1983

Analysis of the gene expression profile of mouse male meiotic germ cells

scientific article

Analysis of the secondary structure of the catalytic domain of mouse Ras exchange factor CDC25Mm

scientific article published on 01 April 1998

Biochemical studies on proacrosin and acrosin from epididymal boar spermatozoa: In vitro translation of boar testicular proacrosin mRNA

scientific article published on 01 July 1986

Bioconversion of lactose/whey to fructose diphosphate with recombinant saccharomyces cerevisiae cells.

scientific article

Calcium signaling and sugar-induced activation of plasma membrane H + -ATPase in Saccharomyces cerevisiae cells

scientific article published on 23 March 2006

Carbonyl cyanide m-chlorophenylhydrazone induced calcium signaling and activation of plasma membrane H(+)-ATPase in the yeast Saccharomyces cerevisiae.

scientific article published on 8 April 2008

Cell cycle analysis in a human cell line (EUE cells)

scientific article published on 01 May 1982

Cell cycle modelling.

scientific article published in January 1986

Cell size modulation by CDC25 and RAS2 genes in Saccharomyces cerevisiae.

scientific article published on June 1989

Characterization and properties of dominant-negative mutants of the ras-specific guanine nucleotide exchange factor CDC25(Mm).

scientific article

Chromosome Separation and Exit from Mitosis in Budding Yeast: Dependence on Growth Revealed by cAMP-Mediated Inhibition

scientific article published on 01 August 1999

Cloning and characterization of a new Ral-GEF expressed in mouse testis.

scientific article published in November 2002

Cloning and characterization of mouse UBPy, a deubiquitinating enzyme that interacts with the ras guanine nucleotide exchange factor CDC25(Mm)/Ras-GRF1

scientific article (publication date: 19 October 2001)

Cloning, sequencing and expression in E. coli of a D-amino acid oxidase cDNA from Rhodotorula gracilis active on cephalosporin C.

scientific article published in October 1997

Control points in Neurospora crassa nuclear division cycle: different effects of the inhibition of protein accumulation

scientific article published on 01 May 1983

Copy number modulation in an autoselection system for stable plasmid maintenance in Saccharomyces cerevisiae.

scientific article published in November 1993

Cytochemical demonstration that acrosin is unavailable in intact ejaculated boar and bull spermatozoa

scientific article published on 01 August 1982

Dansylalanyllysylchloromethyl ketone as a fluorescent probe for localization of acrosin activity in boar and human spermatozoa ⬇️

scientific article published on May 1, 1984

Design and characterization of a new class of inhibitors of ras activation

scientific article

Design, synthesis and biological evaluation of sugar-derived Ras inhibitors

scientific article published on October 2005

Design, synthesis, and biological evaluation of levoglucosenone-derived ras activation inhibitors.

scientific article

Detection of DNA polymerase-beta gene expression by competitive polymerase chain reaction in human ovarian carcinoma cells.

scientific article published on January 1993

Development of a pH-controlled fed-batch system for budding yeast

scientific article published on 01 June 1991

Development of metabolically engineered Saccharomyces cerevisiae cells for the production of lactic acid

article

Efficient production of recombinant DNA proteins in Saccharomyces cerevisiae by controlled high-cell-density fermentation

scientific article published on 01 August 1991

Enhanced expression of heterologous proteins by the use of a superinducible vector in budding yeast.

scientific article published in February 1992

Evidence for adenylate cyclase as a scaffold protein for Ras2-Ira interaction in Saccharomyces cerevisie

scientific article published on 8 February 2014

Evidence for inositol triphosphate as a second messenger for glucose-induced calcium signalling in budding yeast

scientific article published on 15 November 2003

Expression of high levels of human tissue plasminogen activator in yeast under the control of an inducible GAL promoter

scientific article published in August 1992

Flow cytometry and cell cycle kinetics in continuous and fed-batch fermentations of budding yeast.

scientific article published in July 1991

Functional analysis of RalGPS2, a murine guanine nucleotide exchange factor for RalA GTPase

scientific article

Functional coupling of the mammalian EGF receptor to the Ras/cAMP pathway in the yeast Saccharomyces cerevisiae.

scientific article published on 9 January 2008

Functional expression of the transcriptional activator Opaque-2 of Zea mays in transformed yeast

scientific article published on 01 November 1993

G1 phase heterogeneity in exponentially growing Swiss 3T3 mouse fibroblasts

scientific article published on July 1984

Glucose-Derived Ras Pathway Inhibitors: Evidence of Ras–Ligand Binding and Ras–GEF (Cdc25) Interaction Inhibition

scientific article published on 13 August 2007

Glucose-induced calcium influx in budding yeast involves a novel calcium transport system and can activate calcineurin

scientific article published on 21 April 2011

Heterologous gene expression in continuous cultures of budding yeast.

scientific article published in February 1991

Hypotonic stress-induced calcium signaling in Saccharomyces cerevisiae involves TRP-like transporters on the endoplasmic reticulum membrane

scientific article

Identification of different daughter and parent subpopulations in an asynchronously growing Saccharomyces cerevisiae population

scientific article published on 01 March 1997

Identification of gene encoding a putative RNA-helicase, homologous to SKI2, in chromosome VII of Saccharomyces cerevisiae

scientific article

In Saccharomyces cerevisiae a short amino acid sequence facilitates excretion in the growth medium of periplasmic proteins

scientific article published on 01 March 1997

Inhibition of RNA Synthesis in Neurospora crassa Hyphae Treated with Picolinic Acid ⬇️

scientific article published on 01 December 1981

Interaction of cAMP with the CDC25-mediated step in the cell cycle of budding yeast

scientific article published on 01 February 1986

Intracellular protein degradation in Neurospora crassa ⬇️

scientific article published on August 10, 1979

Involvement of Aif1 in apoptosis triggered by lack of Hxk2 in the yeast Saccharomyces cerevisiae.

scientific article published on 18 February 2016

Involvement of CDC25Mm/Ras-GRF1-dependent signaling in the control of neuronal excitability

scientific journal article

Involvement of a cell size control mechanism in the induction and maintenance of oscillations in continuous cultures of budding yeast

scientific article published in August 1990

Kinetics and regulation of tyrosine phosphorylation of the platelet derived growth factor receptor

scientific article published on 01 August 1989

Lack of HXK2 induces localization of active Ras in mitochondria and triggers apoptosis in the yeast Saccharomyces cerevisiae

scientific article published on 5 September 2013

Lactose/whey utilization and ethanol production by transformedSaccharomyces cerevisiae cells

scientific article published on 01 April 1992

Level and Turnover of Polyadenylate-Containing Ribonucleic Acid in Neurospora crassa in Different Steady States of Growth ⬇️

scientific article published on August 15, 1979

Live-cell imaging of endogenous Ras-GTP shows predominant Ras activation at the plasma membrane and in the nucleus in Saccharomyces cerevisiae.

scientific article

Localization of Ras signaling complex in budding yeast

scientific article

MSJ-1, a mouse testis-specific DnaJ protein, is highly expressed in haploid male germ cells and interacts with the testis-specific heat shock protein Hsp70-2

scientific journal article

MSJ-1, a new member of the DNAJ family of proteins, is a male germ cell-specific gene product.

scientific article

Macromolecular syntheses in the cell cycle mutant cdc25 of budding yeast

scientific article published on 01 October 1984

Measurement of Calcium Uptake in Yeast Using45Ca

scientific article published on 02 February 2015

Methods to study the Ras2 protein activation state and the subcellular localization of Ras-GTP in Saccharomyces cerevisiae.

scientific article published in January 2014

Modeling and stochastic simulation of the Ras/cAMP/PKA pathway in the yeast Saccharomyces cerevisiae evidences a key regulatory function for intracellular guanine nucleotides pools

scientific article published on 11 October 2007

Molecular cloning and regulation of the expression of the MET2 gene of Saccharomyces cerevisiae.

scientific article

Molecular cloning and transcriptional analysis of the start gene CDC25 of Saccharomyces cerevisiae.

scientific article published on September 1986

Monitoring Yeast Intracellular Ca2+Levels Using an In Vivo Bioluminescence Assay: Figure 1

scientific article published on 02 February 2015

Mutations at position 1122 in the catalytic domain of the mouse ras-specific guanine nucleotide exchange factor CDC25Mm originate both loss-of-function and gain-of-function proteins.

scientific article published on December 1998

Nuclear Ras2-GTP controls invasive growth in Saccharomyces cerevisiae

scientific article published on 14 November 2013

Oscillations in continuous cultures of budding yeast: a segregated parameter analysis.

scientific article published on August 1988

Overexpression of the CDC25 gene, an upstream element of the ras/adenylyl cyclase pathway in Saccharomyces cerevisiae, allows immunological identification and characterization of its gene product

article

PKA-dependent regulation of Cdc25 RasGEF localization in budding yeast

scientific article published on 25 October 2011

Peptide-nanoparticle ligation mediated by cutinase fusion for the development of cancer cell-targeted nanoconjugates

scientific article published on 13 March 2015

Phospholipase C is required for glucose-induced calcium influx in budding yeast

scientific article published in June 2002

Posttranscriptional regulation of the expression of MET2 gene of Saccharomyces cerevisiae

article

Properties of the catalytic domain of CDC25, a Saccharomyces cerevisiae GDP/GTP exchange factor: comparison of its activity on full-length and C-terminal truncated RAS2 proteins.

scientific article

PtdIns(4,5)P(2) and phospholipase C-independent Ins(1,4,5)P(3) signals induced by a nitrogen source in nitrogen-starved yeast cells

scientific article

Recombinant human nerve growth factor with a marked activity in vitro and in vivo.

scientific article

Reduction of ribosome activity and synthesis of stable RNA in Neurospora crassa

scientific article published on 01 December 1980

Role of guanine nucleotides in the regulation of the Ras/cAMP pathway in Saccharomyces cerevisiae.

scientific article

Selection of yeast cells with a higher plasmid copy number in a Saccharomyces cerevisiae autoselection system

scientific article published in March 1996

Selective cytotoxicity of a bicyclic Ras inhibitor in cancer cells expressing K-Ras(G13D).

scientific article

Simulation of the Ras/cAMP/PKA pathway in budding yeast highlights the establishment of stable oscillatory states.

scientific article

Structure-activity studies on arylamides and arysulfonamides Ras inhibitors

scientific article published on March 2010

The Minimal Active Domain of the Mouse Ras Exchange Factor CDC25Mm

scientific article published on 01 January 1995

The N-terminal region of the Saccharomyces cerevisiae RasGEF Cdc25 is required for nutrient-dependent cell-size regulation

scientific article published in April 2006

The PH-PxxP domain of RalGPS2 promotes PC12 cells differentiation acting as a dominant negative for RalA GTPase activation.

scientific article published on 16 December 2009

The Ras Guanine nucleotide Exchange Factor CDC25Mm is present at the synaptic junction.

scientific article published in August 1997

The acquisition of competence as a possible source of cell cycle variability in mouse fibroblasts

scientific article published on 01 October 1981

The budding yeast RasGEF Cdc25 reveals an unexpected nuclear localization

scientific article

The deubiquitinating enzyme UBPy/USP8 interacts with TrkA and inhibits neuronal differentiation in PC12 cells.

scientific article published on 4 February 2015

The deubiquitinating enzyme mUBPy interacts with the sperm-specific molecular chaperone MSJ-1: the relation with the proteasome, acrosome, and centrosome in mouse male germ cells

scientific article

The glucose-induced polyphosphoinositides turnover in Saccharomyces cerevisiae is not dependent on the CDC25-RAS mediated signal transduction pathway

scientific article published on 01 November 1990

The interaction with PDGF as a source of G1 phase heterogeneity in normal mouse fibroblasts

scientific article

The involvement of calcium carriers and of the vacuole in the glucose-induced calcium signaling and activation of the plasma membrane H(+)-ATPase in Saccharomyces cerevisiae cells.

scientific article

The large N-terminal domain of Cdc25 protein of the yeast Saccharomyces cerevisiae is required for glucose-induced Ras2 activation.

scientific article published on 29 August 2007

The overexpression of the 3′ terminal region of the CDC25 gene of Saccharomyces cerevisiae causes growth inhibition and alteration of purine nucleotides pools

article

The overexpression of the CDC25 gene of Saccharomyces cerevisiae causes a derepression of GAL system and an increase of GAL4 transcription

scientific article published on 01 February 2000

The promoter of Saccharomyces cerevisiae FBA1 gene contains a single positive upstream regulatory element

scientific article published on November 1991

The role of feedback control mechanisms on the establishment of oscillatory regimes in the Ras/cAMP/PKA pathway in S. cerevisiae

scientific article

The sequence of 8.8 kb of yeast chromosome III cloned in lambda PM3270 contains an unusual long ORF (YCR601).

scientific article published on August 1991

The transcription factor Swi4 is target for PKA regulation of cell size at the G1 to S transition in Saccharomyces cerevisiae

scientific article published on 5 June 2015

Timing of nuclear division cycle in Neurospora crassa

scientific article published on 01 April 1981

Total cellular Ca2+ measurements in yeast using flame photometry.

scientific article published on 2 February 2015

Transcription and expression of zein sequences in yeast under natural plant or yeast promoters.

scientific article published on March 1986

Transcriptomic and proteomic analyses of mouse cerebellum reveals alterations in RasGRF1 expression following in vivo chronic treatment with delta 9-tetrahydrocannabinol.

scientific article

Translational regulation of the expression of zein cloned in yeast under an inducible GAL promoter

scientific article published on 01 July 1987

Whi2p links nutritional sensing to actin-dependent Ras-cAMP-PKA regulation and apoptosis in yeast

scientific article

Yeast 2 micron vectors replicate and undergo recombination in Torulaspora delbrueckii.

scientific article

Yeast as a model for Ras signalling

scientific article published in January 2014

mUBPy and MSJ-1, a Deubiquitinating Enzyme and a Molecular Chaperone Specifically Expressed in Testis, Associate with the Acrosome and Centrosome in Mouse Germ Cells

scientific article published on 01 November 2002

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