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List of works by Ralph Lydic

A simulation program examining the use of ratios as raw variables in analyses of variance.

scientific article published in June 1978

Acetylcholine release in the pontine reticular formation of C57BL/6J mouse is modulated by non-M1 muscarinic receptors

scientific article

Adenosine A(1) receptors in mouse pontine reticular formation depress breathing, increase anesthesia recovery time, and decrease acetylcholine release.

scientific article published on February 2013

Adenosine A₁ receptors in mouse pontine reticular formation modulate nociception only in the presence of systemic leptin

scientific article

An interactive program on the PDP-11 for computing organ blood flow from data obtained using the radioactive microsphere technique ⬇️

scientific article published on December 1, 1977

Auditory entrainment of primate drinking rhythms following partial suprachiasmatic nuclei lesions

scientific article

Benzodiazepine site agonists differentially alter acetylcholine release in rat amygdala

scientific article

Buprenorphine disrupts sleep and decreases adenosine concentrations in sleep-regulating brain regions of Sprague Dawley rat.

scientific article

Carbachol in the pontine reticular formation of C57BL/6J mouse decreases acetylcholine release in prefrontal cortex

scientific article

Determination of minimum alveolar concentration for isoflurane and sevoflurane in a rodent model of human metabolic syndrome.

scientific article published on 13 December 2011

Dexmedetomidine-induced sedation does not mimic the neurobehavioral phenotypes of sleep in Sprague Dawley rat

scientific article

Dialysis delivery of an adenosine A1 receptor agonist to the pontine reticular formation decreases acetylcholine release and increases anesthesia recovery time

scientific article published in April 2003

Dialysis delivery of an adenosine A2A agonist into the pontine reticular formation of C57BL/6J mouse increases pontine acetylcholine release and sleep

scientific article

Differential cholinergic activation of G proteins in rat and mouse brainstem: relevance for sleep and nociception

scientific article published on March 2003

Disrupted Sleep and Delayed Recovery from Chronic Peripheral Neuropathy Are Distinct Phenotypes in a Rat Model of Metabolic Syndrome ⬇️

scientific article published on November 1, 2010

Endogenous GABA levels in the pontine reticular formation are greater during wakefulness than during rapid eye movement sleep

scientific article

Enhancement of dorsal raphe discharge by medial pontine reticular formation stimulation depends on behavioral state.

scientific article published on July 1983

Entrainment and masking of circadian drinking rhythms in primates: influence of light intensity

scientific article published on 01 February 1982

Eszopiclone and dexmedetomidine depress ventilation in obese rats with features of metabolic syndrome

scientific article published on May 2014

Experimental control of the diaphragm and laryngeal abductor muscles by brain stem arousal systems

scientific article published on 01 October 1979

Fact and fantasy about sleep and anesthesiology

scientific article published in November 2002

Fentanyl and morphine, but not remifentanil, inhibit acetylcholine release in pontine regions modulating arousal

scientific article published in April 1999

G proteins in rat prefrontal cortex (PFC) are differentially activated as a function of oxygen status and PFC region.

scientific article published on 09 December 2008

GABAergic transmission in rat pontine reticular formation regulates the induction phase of anesthesia and modulates hyperalgesia caused by sleep deprivation

scientific article

Gamma-aminobutyric acid-mediated neurotransmission in the pontine reticular formation modulates hypnosis, immobility, and breathing during isoflurane anesthesia.

scientific article published on December 2008

General anesthesia, sleep, and coma

scientific article

Gradual decay of circadian drinking organization following lesions of the suprachiasmatic nuclei in primates

scientific article published in December 1981

Human brain contains vasopressin and vasoactive intestinal polypeptide neuronal subpopulations in the suprachiasmatic region.

scientific article published on April 1984

Hypocretin (orexin) receptor subtypes differentially enhance acetylcholine release and activate g protein subtypes in rat pontine reticular formation.

scientific article

Hypocretin-1 causes G protein activation and increases ACh release in rat pons.

scientific article

Hypoxia modulates cholinergic but not opioid activation of G proteins in rat hippocampus

scientific article

In vivo metabolic activity of the suprachiasmatic nuclei: non-uniform intranuclear distribution of 14C-labeled deoxyglucose uptake

scientific article

Increased ponto-geniculo-occipital (PGO) wave frequency following central administration of neostigmine

scientific article

Isoflurane-induced changes in righting response and breathing are modulated by RGS proteins

scientific article

Leptin replacement restores supraspinal cholinergic antinociception in leptin-deficient obese mice

scientific article published on 19 April 2009

M2 muscarinic receptors in pontine reticular formation of C57BL/6J mouse contribute to rapid eye movement sleep generation

scientific article

Metabolomic analysis of mouse prefrontal cortex reveals upregulated analytes during wakefulness compared to sleep

scientific article published in Scientific Reports

Microinjection of an adenosine A1 agonist into the medial pontine reticular formation increases tail flick latency to thermal stimulation

scientific article published in December 2002

Morphine inhibits acetylcholine release in rat prefrontal cortex when delivered systemically or by microdialysis to basal forebrain

scientific article

Neurochemical modulators of sleep and anesthetic states.

scientific article published on January 2008

Neurochemistry of Anesthetic States.

scientific article published on 5 March 2018

Nitric oxide in B6 mouse and nitric oxide-sensitive soluble guanylate cyclase in cat modulate acetylcholine release in pontine reticular formation

scientific article published on 19 January 2006

Nociception before and after exercise in rats bred for high and low aerobic capacity

scientific article published on 19 July 2008

Olanzapine causes a leptin-dependent increase in acetylcholine release in mouse prefrontal cortex.

scientific article published on March 2012

Opioid inhibition of rapid eye movement sleep by a specific mu receptor agonist

scientific article

Opioid-induced decreases in rat brain adenosine levels are reversed by inhibiting adenosine deaminase

scientific journal article

Perineural administration of dexmedetomidine in combination with bupivacaine enhances sensory and motor blockade in sciatic nerve block without inducing neurotoxicity in rat

scientific article published on September 2008

Perineural dexmedetomidine added to ropivacaine causes a dose-dependent increase in the duration of thermal antinociception in sciatic nerve block in rat

scientific article

Perineural dexmedetomidine added to ropivacaine for sciatic nerve block in rats prolongs the duration of analgesia by blocking the hyperpolarization-activated cation current

scientific article

Perineural dexmedetomidine provides an increased duration of analgesia to a thermal stimulus when compared with a systemic control in a rat sciatic nerve block

scientific article published on September 2010

Pontine and basal forebrain cholinergic interaction: implications for sleep and breathing

scientific article published on November 2004

Pontine cholinergic mechanisms modulate the cortical electroencephalographic spindles of halothane anesthesia

scientific article published in April 1996

Pontogeniculooccipital waves: spontaneous visual system activity during rapid eye movement sleep.

scientific article published on June 1987

Respiratory neurons of the pneumotaxic center during sleep and wakefulness ⬇️

scientific article published on December 1, 1979

Role of the suprachiasmatic nuclei in the circadian timing system of the squirrel monkey. I. The generation of rhythmicity

scientific article published in May 1984

Role of the suprachiasmatic nuclei in the circadian timing system of the squirrel monkey. II. Light-dark cycle entrainment.

scientific article published in May 1984

Sleep and GABA levels in the oral part of rat pontine reticular formation are decreased by local and systemic administration of morphine.

scientific article published on 19 October 2006

Sleep disruption and increased apneas after pontine microinjection of morphine

scientific article published on November 1, 1992

Sleep disruption is related to allelic variation in the ob gene

scientific article

Sleep duration varies as a function of glutamate and GABA in rat pontine reticular formation

scientific article

Sleep fragmentation delays wound healing in a mouse model of type 2 diabetes

scientific article published on 01 November 2018

Sleep medicine and anesthesia: a new horizon for anesthesiologists

scientific article published in June 2011

Sleep neurobiology: relevance for mechanistic studies of anaesthesia

scientific article published in May 1994

The effects of ethanol upon threshold and response rate for self-stimulation

scientific article published on October 20, 1976

The time-course of dorsal raphe discharge, PGO waves, and muscle tone averaged across multiple sleep cycles

scientific article

Thermal hyperalgesia after sciatic nerve block in rat is transient and clinically insignificant

scientific article published in March 2013

Thermal nociception is decreased by hypocretin-1 and an adenosine A1 receptor agonist microinjected into the pontine reticular formation of Sprague Dawley rat

scientific article

Three dimensional structure of the suprachiasmatic nuclei in the diurnal squirrel monkey (Saimiri sciureus)

scientific article published on 01 May 1980

Volatile anesthesia does not satisfy rapid eye movement sleep debt

scientific article published in October 2011

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