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List of works by Peter J. Trainer

A comparison of the effects of human and ovine corticotropin-releasing hormone on the pituitary-adrenal axis

scientific article published on 01 February 1995

A comparison of the effects of pegvisomant and octreotide on glucose, insulin, gastrin, cholecystokinin, and pancreatic polypeptide responses to oral glucose and a standard mixed meal

scientific article

A consensus on criteria for cure of acromegaly.

scientific article published on 21 April 2010

A critical analysis of the value of simultaneous inferior petrosal sinus sampling in Cushing's disease and the occult ectopic adrenocorticotropin syndrome

scientific article published on 01 February 1999

A giant's step forward

scientific article published in April 2002

A randomized, controlled, multicentre trial comparing pegvisomant alone with combination therapy of pegvisomant and long-acting octreotide in patients with acromegaly

scientific article published on 2 May 2009

A subnormal peak cortisol response to stimulation testing does not predict a subnormal cortisol production rate

scientific article published on 24 February 2009

ACROSTUDY: the first 5 years.

scientific article published on 14 August 2009

Acromegaly surgery in Manchester revisited--the impact of reducing surgeon numbers and the 2010 consensus guidelines for disease remission.

scientific article published on March 2012

Adrenal enlargement and failure of suppression of circulating cortisol by dexamethasone in patients with malignancy.

scientific article published on August 1999

Case for the wider adoption of mass spectrometry-based adrenal steroid testing, and beyond

scientific article published in December 2014

Changes in Arterial Stiffness But Not Carotid Intimal Thickness in Acromegaly

scientific article published in May 2011

Clinical features of GH deficiency and effects of 3 years of GH replacement in adults with controlled Cushing's disease.

scientific article published on 20 January 2010

Clinical use of pegvisomant for the treatment of acromegaly

scientific article

Clinical, radiological and pathological features of patients with Rathke's cleft cysts: tumors that may recur

scientific article published on 01 July 1997

Commentary: Harmonizing growth hormone measurements: learning lessons for the future.

scientific article published on August 2007

Comparison of serum cortisol measurement by immunoassay and liquid chromatography-tandem mass spectrometry in patients receiving the 11β-hydroxylase inhibitor metyrapone

scientific article

Complications of inferior petrosel sinus sampling

scientific article published on 01 April 2000

Computed tomography appearance of the thymus and anterior mediastinum in active Cushing's syndrome

scientific article published on 01 February 1999

Consensus statement on the standardisation of GH assays

scientific article published in July 2006

Control of growth hormone and IGF1 in patients with acromegaly in the UK: responses to medical treatment with somatostatin analogues and dopamine agonists ⬇️

scientific article published on April 24, 2013

Corticosteroid-binding globulin regulates cortisol pharmacokinetics

scientific article published in January 2011

Corticosteroids and pregnancy.

scientific article

Current management practices for acromegaly: an international survey.

scientific article

Disease activity in acromegaly may be assessed 6 weeks after discontinuation of pegvisomant

scientific article published in January 2005

Early diagnosis of acromegaly: computers vs clinicians

scientific article published in August 2011

Editorial: acromegaly--consensus, what consensus?

scientific article published on 01 August 2002

Effect of Growth Hormone in an Experimental Model of Protein Hypercatabolism Induced by Glucocorticoids

scientific article published on 18 September 2006

Effective combination treatment with cabergoline and low-dose pegvisomant in active acromegaly: a prospective clinical trial.

scientific article published on 25 January 2012

Endocrine investigation: Cushing's syndrome

scientific article published in August 1998

Endoscopic transsphenoidal pituitary surgery: evidence of an operative learning curve.

scientific article published in November 2010

Evaluation of pituitary function.

scientific article published on January 2014

Exon splice enhancer mutation (GH-E32A) causes autosomal dominant growth hormone deficiency

scientific article published on 28 August 2007

Expanding the spectrum of mutations in GH1 and GHRHR: genetic screening in a large cohort of patients with congenital isolated growth hormone deficiency

scientific article published on 30 June 2009

Expression of the growth hormone secretagogue receptor in pituitary adenomas and other neuroendocrine tumors

scientific article published in October 1998

Follow-up of pituitary tumor volume in patients with acromegaly treated with pegvisomant in clinical trials

scientific article published on 15 August 2008

GH strongly affects serum concentrations of mannan-binding lectin: evidence for a new IGF-I independent immunomodulatory effect of GH.

scientific article published in November 2001

Gender and age influence the relationship between serum GH and IGF-I in patients with acromegaly

scientific article published in July 2002

Gender, body weight, disease activity, and previous radiotherapy influence the response to pegvisomant

scientific article published on 31 October 2006

Glucose homeostasis and safety in patients with acromegaly converted from long-acting octreotide to pegvisomant

scientific article published on 2 August 2005

Growth hormone assay standardization: a biased view?

scientific article published in May 2004

Growth hormone receptor antagonists therapy for acromegaly.

scientific article published in October 1999

Growth hormone receptor antagonists: discovery, development, and use in patients with acromegaly.

scientific article

Hexarelin as a test of pituitary reserve in patients with pituitary disease

scientific article published in September 1999

High levels of 150-kDa insulin-like growth factor binding protein three ternary complex in patients with acromegaly and the effect of pegvisomant-induced serum IGF-I normalization

scientific article published in February 2004

How common are polycystic ovaries and the polycystic ovarian syndrome in women with Cushing's syndrome?

scientific article published in October 2000

IGF-I measurements in the monitoring of GH therapy.

scientific article published on January 2007

INTERFERBNCE IN MODIFIED IMMUNORADIOMETRIC ASSAY FOR THYROTROPIN

scientific article published in The Lancet

Insulin sensitivity and glucose tolerance improve in patients with acromegaly converted from depot octreotide to pegvisomant

scientific article

Lessons learned from 15 years of KIMS and 5 years of ACROSTUDY.

scientific article published on 21 July 2011

Long-term experience of pegvisomant therapy as a treatment for acromegaly.

scientific article published on 5 November 2008

Long-term treatment of acromegaly with pegvisomant, a growth hormone receptor antagonist

scientific article published in November 2001

Mass spectrometry for the endocrine clinic - much to digest

scientific article published on 25 January 2013

Measurement of salivary cortisol with liquid chromatography-tandem mass spectrometry in patients undergoing dynamic endocrine testing

scientific article published on 19 March 2009

Menstrual abnormalities in women with Cushing's disease are correlated with hypercortisolemia rather than raised circulating androgen levels

scientific article published in September 1998

Modulation of cortisol metabolism by the growth hormone receptor antagonist pegvisomant in patients with acromegaly

scientific article published in July 2001

Next Generation Medical Therapy for Cushing's Syndrome—Can We Measure a Benefit?

scientific article published in April 2014

Nitric oxide modulates the release of corticotropin-releasing hormone from the rat hypothalamus in vitro

scientific article published in March 1993

Novel corticosteroid-binding globulin variant that lacks steroid binding activity

scientific article published on 7 July 2010

Pegvisomant improves insulin sensitivity and reduces overnight free fatty acid concentrations in patients with acromegaly.

scientific article published on 14 April 2009

Pegvisomant in the treatment of acromegaly.

scientific article published on September 2003

Pegvisomant interference in GH assays results in underestimation of GH levels

scientific article published in March 2007

Pegvisomant-induced serum insulin-like growth factor-I normalization in patients with acromegaly returns elevated markers of bone turnover to normal

scientific article published in December 2003

Pituitary-independent effect of octreotide on IGF1 generation

scientific article published on 13 January 2009

Predictors of the outcome of surgical treatment in acromegaly and the value of the mean growth hormone day curve in assessing postoperative disease activity.

scientific article published in April 2001

Quality of Life (QOL) in Patients with Acromegaly Is Severely Impaired: Use of a Novel Measure of QOL: Acromegaly Quality of Life Questionnaire

scientific article published in June 2005

Quantitative growth hormone secretion and final adult height

scientific article

Recent developments in the therapy of acromegaly.

scientific article

Reductions of circulating matrix metalloproteinase 2 and vascular endothelial growth factor levels after treatment with pegvisomant in subjects with acromegaly

scientific article published on 22 August 2006

Regulation of cortisol bioavailability--effects on hormone measurement and action

scientific article published on 14 August 2012

Safety and efficacy of oral octreotide in acromegaly: results of a multicenter phase III trial.

scientific article published on 9 February 2015

Salivary cortisone is a potential biomarker for serum free cortisol.

scientific article published on 4 August 2010

Seeking the optimal target range for insulin-like growth factor I during the treatment of adult growth hormone disorders

scientific article published in December 2003

Serum collagen crosslinks as markers of bone turn-over during GH replacement therapy in growth hormone deficient adults

scientific article published in April 1998

Serum lipoprotein changes following IGF-I normalization using a growth hormone receptor antagonist in acromegaly.

scientific article

Serum regulates cortisol bioactivity by corticosteroid-binding globulin-dependent and independent mechanisms, as revealed by combined bioassay and physicochemical assay approaches

scientific article published on 01 July 2011

Silent growth hormone secreting pituitary adenomas: IGF-1 is not sufficient to exclude growth hormone excess

scientific article published in January 2007

Simultaneous measurement of cortisol and cortisone in human saliva using liquid chromatography-tandem mass spectrometry: application in basal and stimulated conditions

scientific article published on 18 September 2009

Small vessel remodeling and impaired endothelial-dependent dilatation in subcutaneous resistance arteries from patients with acromegaly

scientific article published on 27 January 2009

Spuriously Elevated Serum IGF-1 in Adult Individuals with Delayed Puberty: A Diagnostic Pitfall

scientific article

Successful use of weekly pegvisomant administration in patients with acromegaly

scientific article published in May 2009

Surgical debulking of pituitary macroadenomas causing acromegaly improves control by lanreotide

scientific article published on 19 November 2007

The European Registry on Cushing's syndrome: 2-year experience. Baseline demographic and clinical characteristics

scientific article published on 29 June 2011

The cardiovascular phenotype of a mouse model of acromegaly

scientific article published on 9 March 2009

The effect of growth hormone secretagogues and neuropeptide Y on hypothalamic hormone release from acute rat hypothalamic explants.

scientific article

The effect of pegvisomant-induced serum IGF-I normalization on serum leptin levels in patients with acromegaly.

scientific article

The harmonisation of growth hormone measurements: taking the next steps.

scientific article published on 06 February 2014

The octreotide test dose is not a reliable predictor of the subsequent response to somatostatin analogue therapy in patients with acromegaly

scientific article published in February 2006

The pathophysiology of circulating corticotropin-releasing hormone-binding protein levels in the human

scientific article published in May 1998

The pituitary gland and age-dependent regulation of body composition.

scientific article

The relationship between serum GH and serum IGF-I in acromegaly is gender-specific

scientific article published on 01 November 2001

The use of mass spectrometry to improve the diagnosis and the management of the HPA axis

scientific article published on June 2013

Too much of a good thing

scientific article published in September 1998

Topiramate can induce hypoadrenalism in patients taking oral corticosteroid replacement

scientific article published on 8 January 2009

Treatment of acromegaly improves quality of life, measured by AcroQol

scientific article published on 6 June 2007

Use of a GH receptor antagonist (GHRA) to explore the relationship between GH and IGF-I in adults with severe GH deficiency (GHD).

scientific article

Variation in GH and IGF-I assays limits the applicability of international consensus criteria to local practice

scientific article published on 15 April 2007

Withdrawal of somatostatin analogue therapy in patients with acromegaly is associated with an increased risk of acute biliary problems.

scientific article published on 27 March 2007

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