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List of works by Vladimír Šubr

Chemical conjugation of cowpea mosaic viruses with reactive HPMA-based polymers

scientific article published on 9 June 2010

Coating of DNA/poly(L-lysine) complexes by covalent attachment of poly[N-(2-hydroxypropyl)methacrylamide].

scientific article published in January 2006

Coating of adeno-associated virus with reactive polymers can ablate virus tropism, enable retargeting and provide resistance to neutralising antisera

scientific article published in April 2008

Coating of adenovirus type 5 with polymers containing quaternary amines prevents binding to blood components.

scientific article

Coating of vesicles with hydrophilic reactive polymers

scientific article published on 11 June 2008

Decreased Binding to Proteins and Cells of Polymeric Gene Delivery Vectors Surface Modified with a Multivalent Hydrophilic Polymer and Retargeting through Attachment of Transferrin

scientific article published in Journal of Biological Chemistry

Detection and cellular localisation of the synthetic soluble macromolecular drug carrier pHPMA.

scientific article published on 25 May 2002

Doxorubicin release is not a prerequisite for the in vitro cytotoxicity of HPMA-based pharmaceuticals: in vitro effect of extra drug-free GlyPheLeuGly sequences.

scientific article

E-selectin is a viable route of infection for polymer-coated adenovirus retargeting in TNF-α-activated human umbilical vein endothelial cells

scientific article published on 10 February 2011

Effect of intratumoral injection on the biodistribution and the therapeutic potential of HPMA copolymer-based drug delivery systems

scientific article published on October 2006

Effect of radiotherapy and hyperthermia on the tumor accumulation of HPMA copolymer-based drug delivery systems

scientific article published on 25 November 2006

HPMA copolymers containing doxorubicin bound by a proteolytically or hydrolytically cleavable bond: comparison of biological properties in vitro.

scientific article published on September 2004

HPMA-based polymer therapeutics improve the efficacy of surgery, of radiotherapy and of chemotherapy combinations

scientific article published on December 2010

Human erythrocytes bind and inactivate type 5 adenovirus by presenting Coxsackie virus-adenovirus receptor and complement receptor 1.

scientific article published on 08 January 2009

Image-guided and passively tumour-targeted polymeric nanomedicines for radiochemotherapy

scientific article published on September 2008

In Vivo Nanotoxicity Testing using the Zebrafish Embryo Assay

scientific article

Intracerebral implantation of hydrogel-coupled adhesion peptides: tissue reaction

scientific article published in January 1995

Low Temperature Aqueous Living/Controlled (RAFT) Polymerization of Carboxybetaine Methacrylamide up to High Molecular Weights

scientific article published on 03 June 2011

MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition

scientific article published on 16 September 2019

Micelles of zinc protoporphyrin conjugated to N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer for imaging and light-induced antitumor effects in vivo ⬇️

scientific article published on December 3, 2012

N-(2-Hydroxypropyl)methacrylamide-based polymer conjugates with pH-controlled activation of doxorubicin for cell-specific or passive tumour targeting. Synthesis by RAFT polymerisation and physicochemical characterisation

scientific article published on 7 August 2010

Passive tumour targeting of polymer-coated adenovirus for cancer gene therapy

scientific article published in August 2007

Poly(Hpma)-coated liposomes demonstrate prolonged circulation in mice

scientific article published in January 2001

Poly(ethylene glycol) multiblock copolymer as a carrier of anti-cancer drug doxorubicin

scientific article published in March 2000

Poly[N-(2-hydroxypropyl)meth-acrylamide] Conjugates of Bovine Seminal Ribonuclease. Synthesis, Physicochemical, and Preliminary Biological Evaluation

article published in 2000

Polymer brushes showing non-fouling in blood plasma challenge the currently accepted design of protein resistant surfaces

scientific article published on 03 June 2011

Polymeric drugs based on conjugates of synthetic and natural macromolecules. I. Synthesis and physico-chemical characterisation

scientific article published on 01 February 2000

Polymeric drugs based on conjugates of synthetic and natural macromolecules. II. Anti-cancer activity of antibody or (Fab')(2)-targeted conjugates and combined therapy with immunomodulators

scientific article published on 01 February 2000

Reactive polymers for modification of biologically active molecules and gene delivery vectors

scientific article published on 01 November 2006

Removable nanocoatings for siRNA polyplexes

scientific article published on 10 January 2011

Retargeting polymer-coated adenovirus to the FGF receptor allows productive infection and mediates efficacy in a peritoneal model of human ovarian cancer

scientific article published in March 2008

Simultaneous delivery of doxorubicin and gemcitabine to tumors in vivo using prototypic polymeric drug carriers

scientific article published on 21 March 2009

Singlet oxygen phosphorescence detection in vivo identifies PDT-induced anoxia in solid tumors

scientific article published on 01 June 2019

Synthesis and characterization of HE-24.8: a polymeric contrast agent for magnetic resonance angiography.

scientific article

Targeting adenovirus gene delivery to activated tumour-associated vasculature via endothelial selectins ⬇️

scientific article published on October 18, 2010

Targeting of human and mouse T-lymphocytes by monoclonal antibody-HPMA copolymer-doxorubicin conjugates directed against different T-cell surface antigens

scientific article published on 01 March 1998

Thermoresponsive polymers as promising new materials for local radiotherapy

scientific article published in October 2005

Treatment with HPMA copolymer-based doxorubicin conjugate containing human immunoglobulin induces long-lasting systemic anti-tumour immunity in mice

scientific article published on 25 April 2006

Tropism ablation and stealthing of oncolytic adenovirus enhances systemic delivery to tumors and improves virotherapy of cancer

scientific article published on 18 June 2012

Tumour necrosis factor-alpha increases extravasation of virus particles into tumour tissue by activating the Rho A/Rho kinase pathway ⬇️

scientific article published on August 22, 2011

Virotherapy of ovarian cancer with polymer-cloaked adenovirus retargeted to the epidermal growth factor receptor.

scientific article published on 11 December 2007

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