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List of works by Giorgio Sesti

2009 SIPREC Consensus Document – Executive Summary

3'-UTR OLR1/LOX-1 gene polymorphism and endothelial dysfunction: molecular and vascular data in never-treated hypertensive patients

scientific article

A Randomized Trial Evaluating the Efficacy and Safety of Fast-Acting Insulin Aspart Compared With Insulin Aspart, Both in Combination With Insulin Degludec With or Without Metformin, in Adults With Type 2 Diabetes (Onset 9)

scientific article published on 24 March 2020

A candidate type 2 diabetes polymorphism near the HHEX locus affects acute glucose-stimulated insulin release in European populations: results from the EUGENE2 study

scientific article published on 26 November 2007

A common polymorphism in the promoter of UCP2 contributes to the variation in insulin secretion in glucose-tolerant subjects

scientific article published in May 2003

A fasting insulin-raising allele at IGF1 locus is associated with circulating levels of IGF-1 and insulin sensitivity

scientific article

A functional variant of the dimethylarginine dimethylaminohydrolase-2 gene is associated with chronic kidney disease

scientific article

A functional variant of the dimethylarginine dimethylaminohydrolase-2 gene is associated with insulin sensitivity

scientific article (publication date: 2012)

A greater proportion of participants with type 2 diabetes achieve treatment targets with insulin degludec/liraglutide versus insulin glargine 100 units/mL at 26 weeks: DUAL VIII, a randomized trial designed to resemble clinical practice

scientific article published on 29 January 2020

A polymorphism at IGF1 locus is associated with carotid intima media thickness and endothelium-dependent vasodilatation

scientific article published on 31 October 2013

A review of efficacy and safety data regarding the use of liraglutide, a once-daily human glucagon-like peptide 1 analogue, in the treatment of type 2 diabetes mellitus

scientific article

Activation of the hexosamine pathway leads to phosphorylation of insulin receptor substrate-1 on Ser307 and Ser612 and impairs the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin insulin biosynthetic pathway in RIN pancreatic beta-ce

scientific article published on 4 March 2004

Altered expression of the two naturally occurring human insulin receptor variants in isolated adipocytes of non-insulin-dependent diabetes mellitus patients

scientific article published on December 1991

Altered insulin receptor signalling and β-cell cycle dynamics in type 2 diabetes mellitus

scientific article

Altered pattern of insulin receptor isotypes in skeletal muscle membranes of type 2 (non-insulin-dependent) diabetic subjects

scientific article published on July 1993

An empirical index of insulin sensitivity from short IVGTT: validation against the minimal model and glucose clamp indices in patients with different clinical characteristics

scientific article published on 30 October 2009

Androgens increase insulin receptor mRNA levels, insulin binding, and insulin responsiveness in HEp-2 larynx carcinoma cells

scientific article published on July 1992

Angiotensin (1-7) counteracts the negative effect of angiotensin II on insulin signalling in HUVECs.

scientific article published on 21 March 2013

Angiotensin II impairs the insulin signaling pathway promoting production of nitric oxide by inducing phosphorylation of insulin receptor substrate-1 on Ser312 and Ser616 in human umbilical vein endothelial cells

scientific article published on 25 March 2004

Angiotensin II type 1 receptor, but no type 2 receptor, interferes with the insulin-induced nitric oxide production in HUVECs.

scientific article published on 3 September 2011

Apoptosis in the beta cells: cause or consequence of insulin secretion defect in diabetes?

scientific article

Association between a genetic variant related to glutamic acid metabolism and coronary heart disease in individuals with type 2 diabetes

scientific article published on August 2013

Association between noninvasive fibrosis markers and cardio-vascular organ damage among adults with hepatic steatosis

scientific article

Association between noninvasive fibrosis markers and chronic kidney disease among adults with nonalcoholic fatty liver disease

scientific article

Association between one-hour post-load plasma glucose levels and vascular stiffness in essential hypertension.

scientific article

Association of LDL cholesterol with carotid atherosclerosis in menopausal women affected by the metabolic syndrome

scientific article

Association of hepatic insulin resistance indexes to nonalcoholic fatty liver disease and related biomarkers.

scientific article published on 15 February 2013

Association of insulin resistance indexes to carotid intima-media thickness

scientific article

Asymmetric Dimethylarginine Plasma Levels and Endothelial Function in Newly Diagnosed Type 2 Diabetic Patients ⬇️

scientific article published on October 24, 2012

Asymmetric dimethylarginine, L-arginine, and endothelial dysfunction in essential hypertension

scientific article published in August 2005

Beta-endorphin receptors on cultured and freshly isolated lymphocytes from normal subjects.

scientific article published in August 1989

Branched-Chain Amino Acid Database Integrated in MEDIPAD Software as a Tool for Nutritional Investigation of Mediterranean Populations

scientific article published on 01 October 2018

C-174G polymorphism in the promoter of the interleukin-6 gene is associated with insulin resistance.

scientific article published in August 2005

C-reactive protein induces phosphorylation of insulin receptor substrate-1 on Ser307 and Ser 612 in L6 myocytes, thereby impairing the insulin signalling pathway that promotes glucose transport.

scientific article published on 6 February 2007

CHADS2 and CHA2DS2-VASc scores are independently associated with incident atrial fibrillation: the Catanzaro Atrial Fibrillation Project.

scientific article published on 5 May 2015

Cardiometabolic Risk Profiles and Carotid Atherosclerosis in Individuals With Prediabetes Identified by Fasting Glucose, Postchallenge Glucose, and Hemoglobin A1c Criteria ⬇️

scientific article published on March 7, 2012

Cardiovascular Prevention in Subjects with Impaired Fasting Glucose or Impaired Glucose Tolerance

Carotid artery intima-media thickness is associated with insulin-mediated glucose disposal in nondiabetic normotensive offspring of type 2 diabetic patients.

scientific article published on 12 September 2006

Carotid atherosclerosis associated to metabolic syndrome but not BMI in healthy menopausal women

scientific article published on 10 October 2006

Characterization of left ventricular mass in individuals at risk for type 2 diabetes identified by HbA1c levels according to the American Diabetes Association criteria

scientific article published on 06 November 2014

Chronic HCV infection increases cardiac left ventricular mass index in normotensive patients

scientific article published on 2 June 2014

Clinical risk factors and subclinical target organ damage as predictors of new-onset of atrial fibrillation: the Catanzaro atrial fibrillation project

scientific article published on 5 October 2014

Combination therapy with glucagon-like peptide-1 analogs and insulin: indications and contraindications in coronary artery disease patients

scientific article published on 01 December 2012

Comparison of A1C, fasting and 2-h post-load plasma glucose criteria to diagnose diabetes in Italian Caucasians.

scientific article published on 23 September 2011

Components of the metabolic syndrome and carotid atherosclerosis: role of elevated blood pressure.

scientific article published on 28 February 2005

Correspondence between the International Diabetes Federation criteria for metabolic syndrome and insulin resistance in a cohort of Italian nondiabetic Caucasians: the GISIR database.

scientific article published in May 2007

Creatinine and insulin predict cardiac mass in drug-naïve hypertensive patients

scientific article published on 14 February 2012

Cytokine Release Syndrome in COVID-19 Patients, A New Scenario for an Old Concern: The Fragile Balance between Infections and Autoimmunity

scientific article published on 08 May 2020

DBI mRNA is expressed in endocrine pancreas and its post-translational product DBI(33-50) inhibits insulin release

scientific article published on 01 April 1995

Decreased insulin clearance in individuals with elevated 1-h post-load plasma glucose levels

scientific article

Defects of the insulin receptor substrate (IRS) system in human metabolic disorders

scientific article (publication date: October 2001)

Dietary patterns and 1-h post-load glucose in essential hypertension.

scientific article published on 3 December 2013

Differences in cardiovascular risk profile based on relationship between post-load plasma glucose and fasting plasma levels.

scientific article published in May 2009

Differences in insulin clearance between metabolically healthy and unhealthy obese subjects.

scientific article published on 30 August 2013

Different Patterns of Left Ventricular Hypertrophy in Metabolically Healthy and Insulin-Resistant Obese Subjects

scientific article published on 05 February 2020

Direct modulation of insulin receptor protein tyrosine kinase by vanadate and anti-insulin receptor monoclonal antibodies

scientific article published in May 1988

Distribution of cardiovascular disease and retinopathy in patients with type 2 diabetes according to different classification systems for chronic kidney disease: a cross-sectional analysis of the renal insufficiency and cardiovascular events (RIACE)

scientific article

Distribution of insulin/insulin-like growth factor-I hybrid receptors in human tissues

scientific article published on 01 May 1997

Early molecular and behavioral response to lipopolysaccharide in the WAG/Rij rat model of absence epilepsy and depressive-like behavior, involves interplay between AMPK, AKT/mTOR pathways and neuroinflammatory cytokine release

scientific article

Effect of anti TNFalpha therapy on arterial diameter and wall shear stress and HDL cholesterol

scientific article published in November 2004

Effect of biotin on glucokinase activity, mRNA expression and insulin release in cultured beta-cells

scientific article published on 01 July 1996

Effects of anti-diabetic therapy on overweight/obesity and dyslipidemia: traditional hypoglycemic agents (metformin, sulfonylureas, thiazolidinediones) versus glucagon-like peptide-1 analogs and dipeptidyl peptidase-4 inhibitors

scientific article

Effects of glucagon-like peptide-1 on appetite and body weight: preclinical and clinical data

scientific article

Effects of growth hormone and insulin-like growth factor-1 on cardiac hypertrophy of hypertensive patients.

scientific article published in February 2007

Effects of weight loss in metabolically healthy obese subjects after laparoscopic adjustable gastric banding and hypocaloric diet

scientific article

Elevated 1-h post-load plasma glucose levels in subjects with normal glucose tolerance are associated with unfavorable inflammatory profile

scientific article published on 12 March 2014

Elevated concentrations of liver enzymes and ferritin identify a new phenotype of insulin resistance: effect of weight loss after gastric banding

scientific article published on 24 September 2008

Elevated one-hour post-load plasma glucose levels identifies subjects with normal glucose tolerance but early carotid atherosclerosis

scientific article published on 11 April 2009

Endogenous testosterone and endothelial function in postmenopausal women

scientific article published in February 2007

Endothelial dysfunction and C-reactive protein are risk factors for diabetes in essential hypertension

scientific article published on 10 October 2007

Endothelial dysfunction and C-reactive protein predict the incidence of heart failure in hypertensive patients

scientific article published on 25 November 2020

Endothelial dysfunction and non-alcoholic liver steatosis in hypertensive patients

scientific article published on 12 March 2010

Endothelial dysfunction and subsequent decline in glomerular filtration rate in hypertensive patients

scientific article published on 12 July 2010

Endothelial dysfunction predicts regression of hypertensive cardiac mass

scientific article

Endothelial dysfunction, ADMA and insulin resistance in essential hypertension

scientific article published on 24 January 2009

G972R IRS-1 variant impairs insulin regulation of endothelial nitric oxide synthase in cultured human endothelial cells

scientific article published on 5 January 2004

GLUT2 and glucokinase expression is coordinately regulated by sulfonylurea

scientific article published on 01 July 1999

GRB10 gene and type 2 diabetes in Whites.

scientific article

Glucose tolerance, insulin sensitivity and insulin release in European non-diabetic carriers of a polymorphism upstream of CDKN2A and CDKN2B.

scientific article published on 14 January 2011

Glutamine to arginine substitution at amino acid 84 of mammalian tribbles homolog TRIB3 and CKD in whites with type 2 diabetes

scientific article published in October 2007

Gly460Trp alpha-adducin gene polymorphism and endothelial function in untreated hypertensive patients.

scientific article published in November 2007

HDL cholesterol is an independent predictor of β-cell function decline and incident type 2 diabetes: A longitudinal study

scientific article published on 10 January 2020

Heart rate affects endothelial function in essential hypertension

scientific article published on 11 May 2011

Hemorheological alterations in adults with prediabetes identified by hemoglobin A1c levels.

scientific article published on 21 April 2017

Heterogeneous effect of peroxisome proliferator-activated receptor gamma2 Ala12 variant on type 2 diabetes risk

scientific article published on 01 May 2007

High circulating irisin levels are associated with insulin resistance and vascular atherosclerosis in a cohort of nondiabetic adult subjects

scientific article published on 12 March 2014

Hypoglycemia assessed by continuous glucose monitoring is associated with preclinical atherosclerosis in individuals with impaired glucose tolerance

scientific article

IGF-1 levels link estimated glomerular filtration rate to insulin resistance in obesity: a study in obese, but metabolically healthy, subjects and obese, insulin-resistant subjects

scientific article published on 3 August 2010

IL-18 gene polymorphism and metabolic syndrome

scientific article published on 26 January 2009

IRS1 G972R polymorphism and type 2 diabetes: a paradigm for the difficult ascertainment of the contribution to disease susceptibility of 'low-frequency-low-risk' variants.

scientific article published on 26 June 2009

Impact of Mediterranean Diet on Disease Activity and Gut Microbiota Composition of Rheumatoid Arthritis Patients

scientific article published on 14 December 2020

Impact of common polymorphisms in candidate genes for insulin resistance and obesity on weight loss of morbidly obese subjects after laparoscopic adjustable gastric banding and hypocaloric diet

scientific article published on 28 June 2005

Impact of lowering the criterion for impaired fasting glucose on identification of individuals with insulin resistance. The GISIR database

scientific article published in February 2008

Impaired endothelial function in never-treated hypertensive subjects carrying the Arg972 polymorphism in the insulin receptor substrate-1 gene.

scientific article published in July 2004

Increased O-glycosylation of insulin signaling proteins results in their impaired activation and enhanced susceptibility to apoptosis in pancreatic beta-cells

scientific article published in April 2004

Increased abundance of insulin/IGF-I hybrid receptors in adipose tissue from NIDDM patients

scientific article published on 01 November 1997

Increased abundance of insulin/insulin-like growth factor-I hybrid receptors in skeletal muscle of obese subjects is correlated with in vivo insulin sensitivity

scientific article published on 01 August 1998

Increased expression of low-affinity insulin receptor isoform and insulin/insulin-like growth factor-I hybrid receptors in term placenta from insulin-resistant women with gestational hypertension

scientific article published on 01 August 1996

Increased levels of the Akt-specific phosphatase PH domain leucine-rich repeat protein phosphatase (PHLPP)-1 in obese participants are associated with insulin resistance.

scientific article published on April 2011

Individualized therapy for type 2 diabetes: clinical implications of pharmacogenetic data

scientific article

Individuals With Prediabetes Display Different Age-Related Pathophysiological Characteristics

scientific article published on 01 July 2019

Insulin clearance is associated with carotid artery intima-media thickness.

scientific article published on 22 June 2013

Insulin receptor substrate (IRS) transduction system: distinct and overlapping signaling potential

scientific article

Insulin receptor tyrosine-kinase activity is altered in both muscle and adipose tissue from non-obese normoglycaemic insulin-resistant subjects

scientific article published on 01 January 1995

Insulin resistance and increased intimal medial thickness in glucose tolerant offspring of type 2 diabetic subjects carrying the D298D genotype of endothelial nitric oxide synthase.

scientific article published in February 2006

Insulin secretion in metabolically obese, but normal weight, and in metabolically healthy but obese individuals.

scientific article published on 12 June 2008

Insulin sensitivity, and β-cell function in relation to hemoglobin A1C.

scientific article published on 16 April 2013

Insulin sensitivity, insulin release and glucagon-like peptide-1 levels in persons with impaired fasting glucose and/or impaired glucose tolerance in the EUGENE2 study

scientific article

Insulin sensitivity, β-cell function, and incretin effect in individuals with elevated 1-hour postload plasma glucose levels.

scientific article published on 22 February 2012

Insulin-dependent activation of endothelial nitric oxide synthase is impaired by O-linked glycosylation modification of signaling proteins in human coronary endothelial cells

scientific article

Insulin-like growth factor-1 and glomerular filtration rate in hypertensive patients

scientific article published in March 2009

Insulin-like growth factor-I, inflammatory proteins, and fibrosis in subjects with nonalcoholic fatty liver disease

scientific article published on 11 January 2013

Insulin-resistance HCV infection-related affects vascular stiffness in normotensives

scientific article published on 29 November 2014

Interaction between uric acid and endothelial dysfunction predicts new onset of diabetes in hypertensive patients

scientific article

Interaction between vascular dysfunction and cardiac mass increases the risk of cardiovascular outcomes in essential hypertension.

scientific article

Interleukin-6 impairs the insulin signaling pathway, promoting production of nitric oxide in human umbilical vein endothelial cells

scientific article published on 22 January 2007

Joint effect of insulin signaling genes on insulin secretion and glucose homeostasis.

scientific article

Ketogenic Diet-Induced Weight Loss is Associated with an Increase in Vitamin D Levels in Obese Adults

scientific article published on 09 July 2019

Kidney function and risk factors for left ventricular hypertrophy in untreated uncomplicated essential hypertension

scientific article published on 18 April 2008

Large brachial and common carotid artery diameter in postmenopausal women with carotid atherosclerosis

scientific article published on 23 January 2007

Leptin-stimulated endothelial nitric-oxide synthase via an adenosine 5'-monophosphate-activated protein kinase/Akt signaling pathway is attenuated by interaction with C-reactive protein.

scientific article published on 9 April 2009

Liraglutide achieves A1C targets more often than sitagliptin or exenatide when added to metformin in patients with type 2 diabetes and a baseline A1C <8.0%.

scientific article published in January 2013

Liraglutide once a day versus exenatide twice a day for type 2 diabetes: a 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6).

scientific article

Liraglutide, the once-daily human GLP-1 analog, in the treatment of Type 2 diabetes

scientific article published on 01 July 2010

Low circulating insulin-like growth factor-1 levels are associated with high serum uric acid in nondiabetic adult subjects.

scientific article published on 18 July 2014

Low dose of acetylsalicylic acid and oxidative stress-mediated endothelial dysfunction in diabetes: a short-term evaluation

scientific article

Low insulin-like growth factor-1 levels are associated with anaemia in adult non-diabetic subjects

scientific article published on 5 November 2010

Low plasma insulin-like growth factor-1 levels are associated with reduced insulin sensitivity and increased insulin secretion in nondiabetic subjects.

scientific article published on 5 April 2009

Low-plasma insulin-like growth factor-I levels are associated with impaired endothelium-dependent vasodilatation in a cohort of untreated, hypertensive Caucasian subjects

scientific article published on 22 April 2008

Management of diabetes in older adults.

scientific article published on 7 December 2017

Mechanisms linking empagliflozin to cardiovascular and renal protection

scientific article published on 23 March 2017

Metabolic Syndrome

Metabolic and cardiovascular risk factors in subjects with impaired fasting glucose: the 100 versus 110 mg/dL threshold

scientific article published in October 2007

Metabolically Healthy but Obese Women Have an Intermediate Cardiovascular Risk Profile Between Healthy Nonobese Women and Obese Insulin-Resistant Women

scientific article published on 16 May 2007

Molecular and cellular characterization of the GABAA receptor in the rat pancreas

scientific article

New insights into body composition assessment in obese women

scientific article published in January 1999

Non-alcoholic fatty liver disease is associated with cardiovascular disease in subjects with different glucose tolerance

scientific article published on 01 May 2020

Nonalcoholic fatty liver disease is associated with low circulating levels of insulin-like growth factor-I.

scientific article

One-Hour Postload Plasma Glucose Levels and Left Ventricular Mass in Hypertensive Patients ⬇️

scientific article published on April 22, 2011

One-hour post-load hyperglycemia combined with HbA1c identifies individuals with higher risk of cardiovascular diseases: cross-sectional data from the CATAMERI study

scientific article published on 20 November 2018

One-hour post-load plasma glucose and IGF-1 in hypertensive patients

scientific article published on 18 October 2012

One-hour post-load plasma glucose levels are associated with elevated liver enzymes

scientific article published on 20 July 2011

One-hour postload plasma glucose levels are associated with kidney dysfunction

scientific article

Oxidative Stress Impairs Endothelial Function in Nondipper Hypertensive Patients

scientific article published on 11 June 2010

PTP1B deficiency increases glucose uptake in neonatal hepatocytes: involvement of IRA/GLUT2 complexes.

scientific article published on 5 June 2008

Pathophysiology of insulin resistance.

scientific article published on December 2006

Peptide-based radioimmunoassay for the two isoforms of the human insulin receptor

scientific article published on April 1995

Pharmacogenetics of type 2 diabetes mellitus, the route toward tailored medicine

scientific article published on 07 January 2019

Phenotypic characterization of normotolerant hypertensive patients

scientific article published on 16 September 2011

Plasma complement C3 levels are associated with insulin secretion independently of adiposity measures in non-diabetic individuals

scientific article published on 25 February 2015

Plasma concentration of IGF-I is independently associated with insulin sensitivity in subjects with different degrees of glucose tolerance

scientific article published in January 2005

Plasma interleukin-6 levels are increased in subjects with impaired glucose tolerance but not in those with impaired fasting glucose in a cohort of Italian Caucasians

scientific article published in February 2007

Plasma interleukin-6 levels are independently associated with insulin secretion in a cohort of Italian-Caucasian nondiabetic subjects

scientific article published in July 2006

Plasma kisspeptin levels are associated with insulin secretion in nondiabetic individuals

scientific article

Polymorphisms of the insulin receptor substrate-2 in patients with type 2 diabetes.

scientific article

Positive association between plasma IGF1 and high-density lipoprotein cholesterol levels in adult nondiabetic subjects.

scientific article published on 31 March 2010

Psychological Distress in Patients with Autoimmune Arthritis during the COVID-19 Induced Lockdown in Italy

scientific article published on 18 November 2020

Pulse pressure and endothelial dysfunction in never-treated hypertensive patients.

scientific article published in May 2003

Quantitative analysis of pancreatic glucokinase gene expression in cultured beta cells by competitive polymerase chain reaction

scientific article

Reciprocal association of plasma IGF-1 and interleukin-6 levels with cardiometabolic risk factors in nondiabetic subjects. Diabetes Care 2008;31:1886-1888

Relation of fasting insulin related to insertion/deletion polymorphism of angiotensin-converting enzyme-gene and cardiac mass in never-treated patients with systemic hypertension

scientific article published in November 2003

Relation of low bone mineral density and carotid atherosclerosis in postmenopausal women

scientific article published in July 2004

Renal disease and left atrial remodeling predict atrial fibrillation in patients with cardiovascular risk factors

scientific article published on 04 May 2014

Renal function predicts cardiovascular outcomes in southern Italian postmenopausal women

scientific article published in August 2009

Response to Letter to the Editor: "One-Hour Postload Hyperglycemia: Implications for Prediction and Prevention of Type 2 Diabetes"

scientific article published on 01 March 2019

Role of PC-1 and ACE genes on insulin resistance and cardiac mass in never-treated hypertensive patients. Suggestive evidence for a digenic additive modulation

article

Role of endogenous androgens on carotid atherosclerosis in non-obese postmenopausal women

scientific article published on 28 March 2007

Role of the exon 11 of the insulin receptor gene on insulin binding identified by anti-peptide antibodies

scientific article published on May 1994

Role of transglutaminase 2 in glucose tolerance: knockout mice studies and a putative mutation in a MODY patient

scientific article published in September 2002

Serum uric acid and 1-h postload glucose in essential hypertension

scientific article published on 19 October 2011

Single-nucleotide polymorphism rs7754840 of CDKAL1 is associated with impaired insulin secretion in nondiabetic offspring of type 2 diabetic subjects and in a large sample of men with normal glucose tolerance

scientific article

Switching to once-daily liraglutide from twice-daily exenatide further improves glycemic control in patients with type 2 diabetes using oral agents

scientific article published on 23 March 2010

Sympathovagal balance and 1-h postload plasma glucose in normoglucose tolerant hypertensive patients

scientific article published on 27 March 2015

TRIB3 R84 Variant Is Associated With Impaired Insulin-Mediated Nitric Oxide Production in Human Endothelial Cells

scientific article published on 24 April 2008

TRIB3 R84 variant affects glucose homeostasis by altering the interplay between insulin sensitivity and secretion

scientific article published in July 2010

The -866A/A genotype in the promoter of the human uncoupling protein 2 gene is associated with insulin resistance and increased risk of type 2 diabetes.

scientific article

The Arg972 variant in insulin receptor substrate-1 is associated with an atherogenic profile in offspring of type 2 diabetic patients

scientific article published on July 2003

The Arg972 variant in insulin receptor substrate-1 is associated with an increased risk of secondary failure to sulfonylurea in patients with type 2 diabetes.

scientific article

The CCR2 promoter polymorphism T-960A, but not the serum MCP-1 level, is associated with endothelial function in prediabetic individuals

scientific article

The E23K variant of KCNJ11 encoding the pancreatic beta-cell adenosine 5'-triphosphate-sensitive potassium channel subunit Kir6.2 is associated with an increased risk of secondary failure to sulfonylurea in patients with type 2 diabetes

scientific article published on 4 April 2006

The Gly972-->Arg IRS-1 variant is associated with type 1 diabetes in continental Italy

scientific article published in March 2003

The PEA15 gene is overexpressed and related to insulin resistance in healthy first-degree relatives of patients with type 2 diabetes.

scientific article published on 5 October 2006

The SH2B1 obesity locus and abnormal glucose homeostasis: lack of evidence for association from a meta-analysis in individuals of European ancestry.

scientific article published on 5 October 2013

The SH2B1 obesity locus is associated with myocardial infarction in diabetic patients and with NO synthase activity in endothelial cells

scientific article published on 19 August 2011

The TRIB3 Q84R polymorphism and risk of early-onset type 2 diabetes

scientific article

The TRIB3 R84 variant is associated with increased carotid intima-media thickness in vivo and with enhanced MAPK signalling in human endothelial cells

scientific article published on 5 August 2010

The UCP2 -866 G>A promoter region polymorphism is associated with nonalcoholic steatohepatitis.

scientific article published on 20 November 2014

The common SLC30A8 Arg325Trp variant is associated with reduced first-phase insulin release in 846 non-diabetic offspring of type 2 diabetes patients--the EUGENE2 study

scientific article published on 7 March 2008

The effects of pregnancy steroids on adaptation of beta cells to pregnancy involve the pancreatic glucose sensor glucokinase

scientific article published on 01 November 1997

The functional Q84R polymorphism of mammalian Tribbles homolog TRB3 is associated with insulin resistance and related cardiovascular risk in Caucasians from Italy

scientific article

The place of gliclazide MR in the evolving type 2 diabetes landscape: A comparison with other sulfonylureas and newer oral antihyperglycemic agents

scientific article published on 24 May 2018

The type 2 diabetes and insulin-resistance locus near IRS1 is a determinant of HDL cholesterol and triglycerides levels among diabetic subjects

scientific article

The use of real time continuous glucose monitoring or flash glucose monitoring in the management of diabetes: A consensus view of Italian diabetes experts using the Delphi method

scientific article published on 10 February 2019

Timp3 deficiency in insulin receptor-haploinsufficient mice promotes diabetes and vascular inflammation via increased TNF-alpha

scientific article

Tissue-specific expression of two alternatively spliced isoforms of the human insulin receptor protein.

scientific article published on June 1994

Transgenic mice overexpressing human G972R IRS-1 show impaired insulin action and insulin secretion.

scientific article published on 19 January 2008

Unfavorable inflammatory profile in adults at risk of type 2 diabetes identified by hemoglobin A1c levels according to the American Diabetes Association criteria

scientific article published on 23 September 2014

Uric Acid and Vascular Damage in Essential Hypertension: Role of Insulin Resistance

scientific article published on 19 August 2020

Uric acid and endothelial dysfunction in essential hypertension

scientific article published on 12 April 2006

Usefulness of hemoglobin A1c as a criterion to define the metabolic syndrome in a cohort of italian nondiabetic white subjects

scientific article published on 21 March 2011

Variance of the SGK1 gene is associated with insulin secretion in different European populations: results from the TUEF, EUGENE2, and METSIM studies

scientific article

Variant near ADAMTS9 known to associate with type 2 diabetes is related to insulin resistance in offspring of type 2 diabetes patients--EUGENE2 study

scientific article

Variants of the interleukin-10 promoter gene are associated with obesity and insulin resistance but not type 2 diabetes in caucasian italian subjects

scientific article published on 01 May 2006

Vitamin D and 1-hour post-load plasma glucose in hypertensive patients

scientific article published on 20 February 2014

Weight loss in combination with physical activity improves endothelial dysfunction in human obesity

scientific article published in June 2003

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