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List of works by Margaret O. James

A multi-year study of hepatic biomarkers in coastal fishes from the Gulf of Mexico after the Deepwater Horizon Oil Spill

scientific article

Activities of affinity-isolated glutathione S-transferase (GST) from channel catfish whole intestine

scientific article published on 01 May 2000

Age-Related Changes in miRNA Expression Influence GSTZ1 and Other Drug Metabolizing Enzymes

scientific article published on 01 May 2020

Age-dependent kinetics and metabolism of dichloroacetate: possible relevance to toxicity

scientific article published on 20 December 2007

Binding of 3-hydroxybenzo[a]pyrene to bovine hemoglobin and albumin

scientific article published in January 2003

Bioavailability and biotransformation of 3,4,3′,4′-tetrachlorobiphenyl (TCB) in in situ intestinal preparations of uninduced and TCB induced channel catfish

Bioavailability and biotransformation of 3H-benzo[a]pyrene metabolites in in Situ intestinal preparations of uninduced and BNF-induced channel catfish

Biological effects of Byrsocarpus coccineus in vitro

scientific article published on 26 November 2010

Carcinogenic effects of 1,2-dibromoethane (ethylene dibromide; EDB) in Japanese medaka (Oryzias latipes)

article

Celecoxib influences steroid sulfonation catalyzed by human recombinant sulfotransferase 2A1.

scientific article published on 7 May 2015

Chloride and other anions inhibit dichloroacetate-induced inactivation of human liver GSTZ1 in a haplotype-dependent manner

scientific article

Chloride concentrations in human hepatic cytosol and mitochondria are a function of age.

scientific article

Cytochromes P450 in crustacea

scientific article published in 1998

Demethylation of the pesticide methoxychlor in liver and intestine from untreated, methoxychlor-treated, and 3-methylcholanthrene-treated channel catfish (Ictalurus punctatus): evidence for roles of CYP1 and CYP3A family isozymes

scientific article published in March 2006

Determination of chloral hydrate metabolites in human plasma by gas chromatography-mass spectrometry

scientific article published in March 1999

Determination of dichloroacetate and its metabolites in human plasma by gas chromatography-mass spectrometry

scientific article published in December 1997

Differential expression of α-like glutathione S-transferase (GST) isoforms in catfish intestine

scientific article published on 01 July 2000

Effects of Food Natural Products on the Biotransformation of PCBs

scientific article published in March 2008

Effects of Multiple Doses of Dichloroacetate on GSTZ1 Expression and Activity in Liver and Extrahepatic Tissues of Young and Adult Rats

scientific article published on 01 September 2020

Effects of the pesticide methoxychlor on gene expression in the liver and testes of the male largemouth bass (Micropterus salmoides).

scientific article

Exposure of Rats to Multiple Oral Doses of Dichloroacetate Results in Upregulation of Hepatic GSTs and NQO1

scientific article published on 01 September 2020

GSTZ1 expression and chloride concentrations modulate sensitivity of cancer cells to dichloroacetate

scientific article published on 2 February 2016

Glucuronidation and sulfonation, in vitro, of the major endocrine-active metabolites of methoxychlor in the channel catfish, Ictalurus punctatus, and induction following treatment with 3-methylcholanthrene

scientific article

Glucuronidation of polychlorinated biphenylols and UDP-glucuronic acid concentrations in channel catfish liver and intestine.

scientific article published on 7 January 2008

In vitro inhibition of human hepatic and cDNA-expressed sulfotransferase activity with 3-hydroxybenzo[a]pyrene by polychlorobiphenylols

scientific article

Increased toxicity of benzo(a)pyrene-7,8-dihydrodiol in the presence of polychlorobiphenylols

scientific article

Influence of dietary Coexposure to benzo(a)pyrene on the biotransformation and distribution of 14C-methoxychlor in the channel catfish (Ictalurus punctatus)

scientific article published on 29 January 2009

Inhibition and recovery of rat hepatic glutathione S-transferase zeta and alteration of tyrosine metabolism following dichloroacetate exposure and withdrawal.

scientific article

Inhibition of sulfotransferases by xenobiotics

scientific article

Interactions of cytosolic sulfotransferases with xenobiotics

scientific article

Intestinal and hepatic microsomal metabolism of testosterone and progesterone by a 3 alpha-hydroxysteroid dehydrogenase to the 3 alpha-hydroxy derivatives in the channel catfish, Ictalurus punctatus

scientific article published in November 2002

Intestinal bioavailability and biotransformation of 3,3',4,4'-tetrachlorobiphenyl (CB 77) in in situ preparations of channel catfish following dietary induction of CYP1A.

scientific article published on 20 December 2005

Kinetics and Metabolism of Chloral Hydrate in Children: Identification of Dichloroacetate as a Metabolite

scientific article published on 01 June 1997

Liquid chromatography-tandem mass spectrometry method for the simultaneous determination of delta-ALA, tyrosine and creatinine in biological fluids

scientific article published in December 2004

Mitochondrial Glutathione Transferase Zeta 1 Is Inactivated More Rapidly by Dichloroacetate than the Cytosolic Enzyme in Adult and Juvenile Rat Liver

scientific article published on 01 October 2019

Mitochondrion as a novel site of dichloroacetate biotransformation by glutathione transferase zeta 1.

scientific article

Pharmacokinetics of 2-naphthol following intrapericardial administration, and formation of 2-naphthyl- beta --glucoside and 2-naphthyl sulphate D in the American lobster, Homarus americanus

scientific article published on 01 June 1997

Pharmacokinetics of Oral Dichloroacetate in Dogs

scientific article published on 13 September 2013

Pharmacologic or genetic ablation of maleylacetoacetate isomerase increases levels of toxic tyrosine catabolites in rodents

scientific article published in November 2003

Polychlorobiphenylols are selective inhibitors of human phenol sulfotransferase 1A1 with 4-nitrophenol as a substrate

scientific article published on February 2006

Polyhalogenated biphenyls and phenobarbital: Evaluation as inducers of drug metabolizing enzymes in the sheepshead, Archosargus probatocephalus

scientific article published on 01 August 1981

Preliminary X-ray crystallographic analysis of glutathione transferase zeta 1 (GSTZ1a-1a).

scientific article published on 21 January 2014

Prenatal and postnatal expression of glutathione transferase ζ 1 in human liver and the roles of haplotype and subject age in determining activity with dichloroacetate

scientific article

Purification and Characterization of Hepatic and Intestinal Phenol Sulfotransferase with High Affinity for Benzo[a]pyrene Phenols from Channel Catfish, Ictalurus punctatus

scientific article published on 01 April 2000

Seasonal influences on PCB retention and biotransformation in fish

scientific article published on 14 March 2013

Slow O-demethylation of methyl triclosan to triclosan, which is rapidly glucuronidated and sulfonated in channel catfish liver and intestine

scientific article published on 04 August 2012

Southern flounder hepatic and intestinal metabolism and DNA binding of benzo[a]pyrene (BaP) metabolites following dietary administration of low doses of BaP, BaP-7,8-dihydrodiol or a BaP metabolite mixture

scientific article published on 01 January 1991

Steroid catabolism in marine and freshwater fish ⬇️

scientific article published on October 16, 2010

Stimulation of transactivation of the largemouth bass estrogen receptors alpha, beta-a, and beta-b by methoxychlor and its mono- and bis-demethylated metabolites in HepG2 cells.

scientific article

Sulfation and glucuronidation of benzo[a]pyrene-7,8-dihydrodiol in intestinal mucosa of channel catfish (Ictalurus punctatus)

scientific article published on 01 July 2000

Sulfonation and glucuronidation of hydroxylated bromodiphenyl ethers in human liver

scientific article published on 20 March 2019

Sulfonation of 17beta-estradiol and inhibition of sulfotransferase activity by polychlorobiphenylols and celecoxib in channel catfish, Ictalurus punctatus

scientific article

Sulfotransferase 2A1 forms estradiol-17-sulfate and celecoxib switches the dominant product from estradiol-3-sulfate to estradiol-17-sulfate

scientific article

The influence of human GSTZ1 gene haplotype variations on GSTZ1 expression.

scientific article

The state of in vitro science for use in bioaccumulation assessments for fish

scientific article published on January 2009

Triclosan as a substrate and inhibitor of 3'-phosphoadenosine 5'-phosphosulfate-sulfotransferase and UDP-glucuronosyl transferase in human liver fractions

scientific article

Triclosan is a potent inhibitor of estradiol and estrone sulfonation in sheep placenta

scientific article published on 18 March 2009

Unified gas chromatographic-mass spectrometric method for quantitating tyrosine metabolites in urine and plasma

scientific article

Use ofIn VitroAbsorption, Distribution, Metabolism, and Excretion (ADME) Data in Bioaccumulation Assessments for Fish

scientific article published in 2007

cDNA and protein sequence of a major form of P450, CYP2L, in the hepatopancreas of the spiny lobster, Panulirus argus.

scientific article published on May 1996

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