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List of works by Astrid M van der Sar

A Novel extracytoplasmic function (ECF) sigma factor regulates virulence in Pseudomonas aeruginosa

scientific journal article

A star with stripes: zebrafish as an infection model

scientific article published in October 2004

A transgenic zebrafish model for the in vivo study of the blood and choroid plexus brain barriers using claudin 5.

scientific article published on 2 February 2018

Analysis of SecA2-dependent substrates in Mycobacterium marinum identifies protein kinase G (PknG) as a virulence effector.

scientific article

Animal models of tuberculosis: zebrafish

scientific article

Assessing Pseudomonas Virulence with Nonmammalian Host: Zebrafish

scientific article published in 2014

Correction: First Demonstration of Antigen Induced Cytokine Expression by CD4-1+ Lymphocytes in a Poikilotherm: Studies in Zebrafish (Danio rerio).

scientific article published on 21 December 2016

Cyanovirin-N inhibits mannose-dependent Mycobacterium-C-type lectin interactions but does not protect against murine tuberculosis

scientific article

Discovery of zebrafish (Danio rerio) interleukin-23 alpha (IL-23α) chain, a subunit important for the formation of IL-23, a cytokine involved in the development of Th17 cells and inflammation

scientific article published on 16 February 2011

ESX-5-deficient Mycobacterium marinum is hypervirulent in adult zebrafish.

scientific article published on 15 February 2012

EspH is a hypervirulence factor for Mycobacterium marinum and essential for the secretion of the ESX-1 substrates EspE and EspF

scientific article published on 13 August 2018

Eye defects in receptor protein-tyrosine phosphatase alpha knock-down zebrafish

scientific article published on March 2002

First Demonstration of Antigen Induced Cytokine Expression by CD4-1+ Lymphocytes in a Poikilotherm: Studies in Zebrafish (Danio rerio).

scientific article published on 17 June 2015

Galectin-4 Reduces Migration and Metastasis Formation of Pancreatic Cancer Cells

scientific article

Genome-wide transposon mutagenesis indicates that Mycobacterium marinum customizes its virulence mechanisms for survival and replication in different hosts

scientific article published on 17 February 2015

Identification and real-time imaging of a myc-expressing neutrophil population involved in inflammation and mycobacterial granuloma formation in zebrafish

scientific article published on 22 May 2007

Identification of a glycosyltransferase from Mycobacterium marinum involved in addition of a caryophyllose moiety in lipooligosaccharides

scientific article published on 4 March 2011

Infection of zebrafish embryos with intracellular bacterial pathogens

scientific article

Infection of zebrafish embryos with live fluorescent Streptococcus pneumoniae as a real-time pneumococcal meningitis model.

scientific article

Mannan core branching of lipo(arabino)mannan is required for mycobacterial virulence in the context of innate immunity

scientific article published on 22 August 2013

Modeling tuberculous meningitis in zebrafish using Mycobacterium marinum.

scientific article

MyD88 innate immune function in a zebrafish embryo infection model

scientific article published on April 2006

Mycobacterial secretion systems ESX-1 and ESX-5 play distinct roles in host cell death and inflammasome activation

scientific article published on 28 September 2011

Mycobacterium marinum strains can be divided into two distinct types based on genetic diversity and virulence

scientific article

Prophylactic administration of chicken cathelicidin-2 boosts zebrafish embryonic innate immunity

scientific article

Specificity of the zebrafish host transcriptome response to acute and chronic mycobacterial infection and the role of innate and adaptive immune components.

scientific article published on 5 May 2009

Structure and function of RNase AS, a polyadenylate-specific exoribonuclease affecting mycobacterial virulence in vivo

scientific article

The CXCR3-CXCL11 signaling axis mediates macrophage recruitment and dissemination of mycobacterial infection.

scientific article published on 8 January 2015

The role of gamma interferon in innate immunity in the zebrafish embryo

scientific article published on 24 September 2009

Towards a new combination therapy for tuberculosis with next generation benzothiazinones

scientific article

Transcriptome profiling of adult zebrafish at the late stage of chronic tuberculosis due to Mycobacterium marinum infection.

scientific article

Transmission of Mycobacterium marinum from fish to a very young child.

scientific article

Tubercle bacilli rely on a type VII army for pathogenicity

scientific article published on 02 August 2012

Unexpected link between lipooligosaccharide biosynthesis and surface protein release in Mycobacterium marinum

scientific article

Zebrafish development and regeneration: new tools for biomedical research

scientific article

Zebrafish embryo screen for mycobacterial genes involved in the initiation of granuloma formation reveals a newly identified ESX-1 component

scientific article published on 3 March 2011

Zebrafish embryos as a model host for the real time analysis of Salmonella typhimurium infections

scientific article published on September 2003