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List of works by Peter Johnson

18F-FDG PET/CT in Lymphoma: Has Imaging-Directed Personalized Medicine Become a Reality?

scientific article published on 10 August 2017

A phase I clinical trial of irinotecan and carboplatin in patients with extensive stage small cell lung cancer.

scientific article published on 15 August 2012

Acquisition of potential N-glycosylation sites in the immunoglobulin variable region by somatic mutation is a distinctive feature of follicular lymphoma

scientific article

Adapted Treatment Guided by Interim PET-CT Scan in Advanced Hodgkin's Lymphoma.

scientific article published on June 2016

Addition of SRL 172 to standard chemotherapy in small cell lung cancer (SCLC) improves symptom control

scientific article published on 01 February 2005

Addition of rituximab to chlorambucil produces superior event-free survival in the treatment of patients with extranodal marginal-zone B-cell lymphoma: 5-year analysis of the IELSG-19 Randomized Study

scientific article

All that glitters is not gold - new reconstruction methods using Deauville criteria for patient reporting.

scientific article

Antagonistic human FcγRIIB (CD32B) antibodies have anti-tumor activity and overcome resistance to antibody therapy in vivo.

scientific article

Antibodies to Costimulatory Receptor 4-1BB Enhance Anti-tumor Immunity via T Regulatory Cell Depletion and Promotion of CD8 T Cell Effector Function

scientific article published on 13 November 2018

Antibody Tumor Targeting Is Enhanced by CD27 Agonists through Myeloid Recruitment.

scientific article published on 21 November 2017

Antibody-induced intracellular signaling works in combination with radiation to eradicate lymphoma in radioimmunotherapy

scientific article published on 23 October 2003

Antigenic modulation limits the efficacy of anti-CD20 antibodies: implications for antibody selection

scientific article published on 11 March 2010

Augmentation of CD134 (OX40)-dependent NK anti-tumour activity is dependent on antibody cross-linking

scientific article

BAG-1 immunostaining and survival in early breast cancer

scientific article published on 01 August 2001

BCR signaling contributes to autophagy regulation in chronic lymphocytic leukemia

scientific article published on 28 August 2019

Bortezomib therapy in patients with relapsed or refractory lymphoma: potential correlation of in vitro sensitivity and tumor necrosis factor alpha response with clinical activity

scientific article

Breast cancer is a promising target for vaccination using cancer-testis antigens known to elicit immune responses.

scientific article

CD27 costimulation contributes substantially to the expansion of functional memory CD8(+) T cells after peptide immunization.

scientific article published in October 2013

CD40 induces interleukin-6 gene transcription in dendritic cells: regulation by TRAF2, AP-1, NF-kappa B, AND CBF1.

scientific article published on 8 March 2002

CHOP versus GEM-P in previously untreated patients with peripheral T-cell lymphoma (CHEMO-T): a phase 2, multicentre, randomised, open-label trial.

scientific article

Chemokine expression in IBD. Mucosal chemokine expression is unselectively increased in both ulcerative colitis and Crohn's disease.

scientific article

Chemotherapy: Advanced Hodgkin lymphoma--balancing toxicity and cure

scientific article published on 06 September 2011

Clinical and Biological Effects of an Agonist Anti-CD40 Antibody: A Cancer Research UK Phase I Study

scientific article published on 14 January 2015

Comparison of ABVD and alternating or hybrid multidrug regimens for the treatment of advanced Hodgkin's lymphoma: results of the United Kingdom Lymphoma Group LY09 Trial (ISRCTN97144519).

scientific article published on 28 November 2005

Comparison of Outcomes in Studies of Advanced Hodgkin's Lymphoma

scientific article published on 01 July 2006

Concordance between four European centres of PET reporting criteria designed for use in multicentre trials in Hodgkin lymphoma

scientific article published on 27 May 2010

Conformation of the human immunoglobulin G2 hinge imparts superagonistic properties to immunostimulatory anticancer antibodies.

scientific article

Current treatment paradigms for advanced stage Hodgkin lymphoma

scientific article published on 08 November 2018

DNA vaccines to attack cancer

scholarly article

De novo treatment of diffuse large B-cell lymphoma with rituximab, cyclophosphamide, vincristine, gemcitabine, and prednisolone in patients with cardiac comorbidity: a United Kingdom National Cancer Research Institute trial.

scientific article published on 12 November 2013

Defects in lymphocyte subsets and serological memory persist a median of 10 years after high-dose therapy and autologous progenitor cell rescue for malignant lymphoma.

scientific article published on 14 May 2012

Determinants of ovarian function after response-adapted therapy in patients with advanced Hodgkin's lymphoma (RATHL): a secondary analysis of a randomised phase 3 trial

scientific article published on 13 September 2018

Development, validation and application of ELISAs for pharmacokinetic and HACA assessment of a chimeric anti-CD40 monoclonal antibody in human serum

scientific article published on 24 September 2010

Differential impact of CD27 and 4-1BB costimulation on effector and memory CD8 T cell generation following peptide immunization.

scientific article published on 23 May 2014

Distinct genetic changes reveal evolutionary history and heterogeneous molecular grade of DLBCL with MYC/BCL2 double-hit

scientific article published on 16 December 2019

Distinct promoters mediate constitutive and inducible Bcl-XL expression in malignant lymphocytes.

scientific article published on 18 September 2006

Enumeration and phenotypic assessment of human plasmacytoid and myeloid dendritic cells in whole blood

scientific article published in April 2010

Eradication of lymphoma by CD8 T cells following anti-CD40 monoclonal antibody therapy is critically dependent on CD27 costimulation

scientific article published on 20 February 2007

Establishment of a UK-wide network to facilitate the acquisition of quality assured FDG-PET data for clinical trials in lymphoma

scientific article

Ex vivo assays of dendritic cell activation and cytokine profiles as predictors of in vivo effects in an anti-human CD40 monoclonal antibody ChiLob 7/4 phase I trial

scientific article

Fc gamma receptor IIb on target B cells promotes rituximab internalization and reduces clinical efficacy.

scientific article

Fcγ receptor dependency of agonistic CD40 antibody in lymphoma therapy can be overcome through antibody multimerization

scientific article published on 14 July 2014

FcγRΙΙB controls the potency of agonistic anti-TNFR mAbs.

scientific article published on 31 March 2013

Final Results of the IELSG-19 Randomized Trial of Mucosa-Associated Lymphoid Tissue Lymphoma: Improved Event-Free and Progression-Free Survival With Rituximab Plus Chlorambucil Versus Either Chlorambucil or Rituximab Monotherapy.

scientific article published on 29 March 2017

Focal skeletal FDG uptake indicates poor prognosis in cHL regardless of extent and first-line chemotherapy

scientific article published on 22 May 2019

Gemcitabine alone or in combination with cisplatin in patients with advanced or metastatic cholangiocarcinomas or other biliary tract tumours: a multicentre randomised phase II study - The UK ABC-01 Study

scientific article

Gemcitabine plus carboplatin versus mitomycin, ifosfamide, and cisplatin in patients with stage IIIB or IV non-small-cell lung cancer: a phase III randomized study of the London Lung Cancer Group.

scientific article

Gene-expression profiling of bortezomib added to standard chemoimmunotherapy for diffuse large B-cell lymphoma (REMoDL-B): an open-label, randomised, phase 3 trial

article

Genome-wide promoter methylation of hairy cell leukemia

scientific article published on 01 February 2019

Glycosylation of surface Ig creates a functional bridge between human follicular lymphoma and microenvironmental lectins

scientific article

Hepatitis C virus and GBV-C virus prevalence among patients with B-cell lymphoma in different European regions: a case-control study of the International Extranodal Lymphoma Study Group.

scientific article published on 21 November 2011

IL-10 production by CLL cells is enhanced in the anergic IGHV mutated subset and associates with reduced DNA methylation of the IL10 locus

scientific article published on 28 November 2016

IL-4 enhances expression and function of surface IgM in CLL cells.

scientific article

Ibrutinib therapy releases leukemic surface IgM from antigen drive in chronic lymphocytic leukemia patients

scientific article published on 29 October 2018

Identification in CLL of circulating intraclonal subgroups with varying B-cell receptor expression and function

scientific article

Induction of cytosolic calcium flux by CD20 is dependent upon B Cell antigen receptor signaling.

scientific article published on 21 April 2008

Influence of the MDM2 single nucleotide polymorphism SNP309 on tumour development in BRCA1 mutation carriers

scientific article published on 24 March 2006

Intestinal strictures: a new complication of treatment for primary gastrointestinal diffuse large B-cell lymphoma

scientific article published on 22 January 2008

Lectin binding to surface Ig variable regions provides a universal persistent activating signal for follicular lymphoma cells.

scientific article published on 20 July 2015

Long-term follow-up of MCL patients treated with single-agent ibrutinib: updated safety and efficacy results

scientific article

Low-dose lenograstim is as effective as standard dose in shortening neutrophil engraftment time following myeloablative chemotherapy and peripheral blood progenitor cell rescue

scientific article published on 13 April 2007

Lymphoma: turning biology into cures

scientific article published in December 2016

Maximum tumor diameter is associated with event-free survival in PET-negative patients with stage I/IIA Hodgkin lymphoma

scientific article published on 01 January 2020

Mcl-1 is required for Akata6 B-lymphoma cell survival and is converted to a cell death molecule by efficient caspase-mediated cleavage.

scientific article published on June 2004

Metabolic heterogeneity on baseline 18FDG-PET/CT scan is a predictor of outcome in primary mediastinal B-cell lymphoma.

scientific article published on 2 May 2018

Microscopic Intratumoral Dosimetry of Radiolabeled Antibodies Is a Critical Determinant of Successful Radioimmunotherapy in B-Cell Lymphoma

scientific article published on 01 February 2007

Molecular High-Grade B-Cell Lymphoma: Defining a Poor-Risk Group That Requires Different Approaches to Therapy ⬇️

scientific article published on 03 December 2018

Mutation screening using formalin-fixed paraffin-embedded tissues: a stratified approach according to DNA quality

scientific article published on 16 May 2018

Nivolumab for Relapsed/Refractory Diffuse Large B-Cell Lymphoma in Patients Ineligible for or Having Failed Autologous Transplantation: A Single-Arm, Phase II Study

scientific article published on 08 January 2019

Novel antibodies targeting immune regulatory checkpoints for cancer therapy.

scientific article published on August 2013

Optimising anti-tumour CD8 T-cell responses using combinations of immunomodulatory antibodies.

scientific article published on September 2008

Optimizing therapy in advanced-stage Hodgkin lymphoma.

scientific article published on 2 March 2018

Options for first line therapy of Hodgkin lymphoma

scientific article published on 01 June 2019

Outcome of Elderly Patients with Diffuse Large B-cell Lymphoma Treated with R-CHOP: Results from the UK NCRI R-CHOP14v21 trial with combined analysis of molecular characteristics with the DSHNHL RICOVER-60 trial

scientific article

PET-CT for staging and early response: results from the Response-Adapted Therapy in Advanced Hodgkin Lymphoma study

scientific article published on 8 January 2016

Pharmacological inhibitors of NF-κB accelerate apoptosis in chronic lymphocytic leukaemia cells

scientific article published on 21 August 2006

Phase 1/2 study of fractionated 131I-rituximab in low-grade B-cell lymphoma: the effect of prior rituximab dosing and tumor burden on subsequent radioimmunotherapy

scientific article published on 12 December 2008

Phase I Study of the Novel Enhancer of Zeste Homolog 2 (EZH2) Inhibitor GSK2816126 in Patients with Advanced Hematologic and Solid Tumors

scientific article published on 30 August 2019

Phase I pharmacokinetic and pharmacodynamic study of the bioreductive drug RH1

Phase I study of KW-2478, a novel Hsp90 inhibitor, in patients with B-cell malignancies.

scientific article

Phase I study of vinflunine administered as a 10-minute infusion on days 1 and 8 every 3 weeks

scientific article published on May 2006

Phase II study of ISIS 3521, an antisense oligodeoxynucleotide to protein kinase C alpha, in patients with previously treated low-grade non-Hodgkin's lymphoma

scientific article

Population-based demographic study of karyotypes in 1709 patients with adult acute myeloid leukemia

scientific article published on 01 March 2006

Positive and negative selection to reduce tumour contamination in peripheral blood stem cell harvests

scientific article published in September 2000

Positron Emission Tomography Score Has Greater Prognostic Significance Than Pretreatment Risk Stratification in Early-Stage Hodgkin Lymphoma in the UK RAPID Study

scientific article published on 21 May 2019

Prediction of single-nucleotide substitutions that result in exon skipping: identification of a splicing silencer in BRCA1 exon 6.

scientific article published on 8 March 2011

Primary mediastinal B-cell lymphoma

scientific article published on 01 December 2007

Primary mediastinal large B-cell lymphoma

scholarly article by Maurizio Martelli et al published May 2017 in Critical Reviews in Oncology Hematology

Prognostic models for primary mediastinal (thymic) B-cell lymphoma derived from 18-FDG PET/CT quantitative parameters in the International Extranodal Lymphoma Study Group (IELSG) 26 study.

scientific article

RIVA - a phase IIa study of rituximab and varlilumab in relapsed or refractory B-cell malignancies: study protocol for a randomized controlled trial

scientific article published on 9 November 2018

Randomized Phase III Trial of Ibrutinib and Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone in Non-Germinal Center B-Cell Diffuse Large B-Cell Lymphoma.

scientific article

Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma.

scientific article published on 21 December 2015

Resources-Stratified Guidelines for Classical Hodgkin Lymphoma

scientific article published on 09 March 2020

Response-adapted therapy in Hodgkin lymphoma

scientific article published on 01 June 2017

Results of a trial of PET-directed therapy for early-stage Hodgkin's lymphoma

scientific article published in April 2015

Rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisolone in patients with newly diagnosed diffuse large B-cell non-Hodgkin lymphoma: a phase 3 comparison of dose intensification with 14-day versus 21-day cycles

scientific article

S-adenosylhomocysteine hydrolase inhibition by 3-deazaneplanocin A analogues induces anti-cancer effects in breast cancer cell lines and synergy with both histone deacetylase and HER2 inhibition.

scientific article published on 17 June 2010

Safety and clinical activity of a combination therapy comprising two antibody-based targeting agents for the treatment of non-Hodgkin lymphoma: results of a phase I/II study evaluating the immunoconjugate inotuzumab ozogamicin with rituximab

scientific article

Secondary malignant neoplasms, progression-free survival and overall survival in patients treated for Hodgkin lymphoma: A systematic review and meta-analysis of randomized clinical trials.

scientific article published on 14 September 2017

Short duration immunochemotherapy followed by radioimmunotherapy consolidation is effective and well tolerated in relapsed follicular lymphoma: 5-year results from a UK National Cancer Research Institute Lymphoma Group study.

scientific article published on 05 February 2016

Short peptides derived from the BAG-1 C-terminus inhibit the interaction between BAG-1 and HSC70 and decrease breast cancer cell growth

scientific article

Stratified medicine for cancer therapy.

scientific article published on March 2012

Surface IgM expression and function are associated with clinical behavior, genetic abnormalities, and DNA methylation in CLL.

scientific article published on 14 June 2016

T-cell non-Hodgkin's lymphoma: treatment outcomes and survival in 3 large UK centres

scientific article published on 04 September 2007

Targeting BTK with ibrutinib in relapsed or refractory mantle-cell lymphoma

scientific article

The Dual Syk/JAK Inhibitor Cerdulatinib Antagonizes B-cell Receptor and Microenvironmental Signaling in Chronic Lymphocytic Leukemia

scientific article published on 3 October 2016

The PI3K/mTOR inhibitor PF-04691502 induces apoptosis and inhibits microenvironmental signaling in CLL and the Eµ-TCL1 mouse model

scientific article published on 8 May 2015

The nuclear BAG-1 isoform, BAG-1L, enhances oestrogen-dependent transcription.

scientific article published in August 2003

The prognosis of MYC translocation positive diffuse large B-cell lymphoma depends on the second hit.

scientific article published on 30 March 2015

The role of MNK proteins and eIF4E phosphorylation in breast cancer cell proliferation and survival

scientific article

Thioflavin S (NSC71948) interferes with Bcl-2-associated athanogene (BAG-1)-mediated protein-protein interactions.

scientific article published on 18 August 2009

Training improves the interobserver agreement of the expert positron emission tomography review panel in primary mediastinal B-cell lymphoma: interim analysis in the ongoing International Extranodal Lymphoma Study Group-37 study.

scientific article

Transmission of diffuse large B-cell lymphoma by an allogeneic stem-cell transplant

article

Universal N-glycosylation sites introduced into the B-cell receptor of follicular lymphoma by somatic mutation: a second tumorigenic event?

scientific article published on 01 March 2006

Use of a biosimilar granulocyte colony-stimulating factor for peripheral blood stem cell mobilization: an analysis of mobilization and engraftment

scientific article published on 25 April 2013

Validation and comparison of two multiplex technologies, Luminex and Mesoscale Discovery, for human cytokine profiling

scientific article published on 5 November 2008

Variable Responses of MYC Translocation Positive Lymphoma Cell Lines To Different Combinations of Novel Agents: Impact of BCL2 Family Protein Expression.

scientific article published on 25 July 2018

Weekly versus twice weekly bortezomib given in conjunction with rituximab, in patients with recurrent follicular lymphoma, mantle cell lymphoma and Waldenström macroglobulinaemia

scientific article published on 29 September 2010

Whole-brain radiotherapy or autologous stem-cell transplantation as consolidation strategies after high-dose methotrexate-based chemoimmunotherapy in patients with primary CNS lymphoma: results of the second randomisation of the International Extran

scientific article published on 17 October 2017

Will histone deacetylase inhibitors require combination with other agents to fulfil their therapeutic potential?

scientific article published on 19 August 2008

[18F]fluorodeoxyglucose positron emission tomography predicts survival after chemoimmunotherapy for primary mediastinal large B-cell lymphoma: results of the International Extranodal Lymphoma Study Group IELSG-26 Study.

scientific article published on 05 May 2014

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