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List of works by Sundeep Khosla

A Crisis in the Treatment of Osteoporosis

scientific article published on 28 June 2016

A DNA binding mutation in estrogen receptor-α leads to suppression of Wnt signaling via β-catenin destabilization in osteoblasts

scientific article

A Lot of Progress, With More to Be Done: A Response to NIH Pathways to Prevention Report "Research Gaps for Long-Term Drug Therapies for Osteoporotic Fracture Prevention"

scientific article published on 25 July 2019

A bone structural basis for fracture risk in diabetes

scientific article published on 16 September 2008

A defect in renal calcium conservation may contribute to the pathogenesis of postmenopausal osteoporosis

scientific article published on 01 June 1998

A distal forearm fracture in childhood is associated with an increased risk for future fragility fractures in adult men, but not women.

scientific article published on August 2013

A fragment of the hypophosphatemic factor, MEPE, requires inducible cyclooxygenase-2 to exert potent anabolic effects on normal human marrow osteoblast precursors

scientific article published in December 2004

A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues

scientific article published in 2022

A population-based assessment of rates of bone loss at multiple skeletal sites: evidence for substantial trabecular bone loss in young adult women and men

scientific article

A potentially deleterious role of IGFBP-2 on bone density in aging men and women

scientific article

A randomised controlled trial of low-dose aspirin for the prevention of fractures in healthy older people: protocol for the ASPREE-Fracture substudy

scientific article published on 21 May 2015

A randomized placebo-controlled trial of short-term graded transdermal estradiol in healthy gonadotropin-releasing hormone agonist-suppressed pre- and postmenopausal women: effects on serum markers of bone turnover, insulin-like growth factor-I, and

scientific article published on 28 December 2004

A unitary model for involutional osteoporosis: estrogen deficiency causes both type I and type II osteoporosis in postmenopausal women and contributes to bone loss in aging men.

scientific article

Abdominal aortic calcification, BMD, and bone microstructure: a population-based study.

scientific article published on October 2008

Ability of circulating human hematopoietic lineage negative cells to support hematopoiesis

scientific article published on January 2015

Abnormalities of parathyroid hormone secretion in elderly women that are reversible by short term therapy with 1,25-dihydroxyvitamin D3.

scientific article

Accelerated osteocyte senescence and skeletal fragility in mice with type 2 diabetes

scientific article published on 07 April 2020

Addressing the Crisis in the Treatment of Osteoporosis: A Path Forward

scientific article published on 29 December 2016

Age- and sex-specific differences in the factor of risk for vertebral fracture: a population-based study using QCT.

scientific article published in September 2006

Age-dependence of femoral strength in white women and men.

scientific article

Age-dependent renal cortical microvascular loss in female mice

scientific article published on 7 February 2012

Androgen effects on bone metabolism: recent progress and controversies

scientific article

Androgen therapy in women: an Endocrine Society Clinical Practice guideline.

scientific article published on 3 October 2006

Androgens and bone

scientific article published on 17 October 2008

Androgens, estrogens, and bone turnover in men

scientific article published on 01 May 2003

Applications of a New Handheld Reference Point Indentation Instrument Measuring Bone Material Strength

scientific article published on 24 September 2013

Are the endocrine society's clinical practice guidelines on androgen therapy in women misguided? A commentary-response

scientific article published in November 2007

Assessing forearm fracture risk in postmenopausal women

scientific article

Association of hip strength estimates by finite-element analysis with fractures in women and men

scientific article

Automatic multi-parametric quantification of the proximal femur with quantitative computed tomography

scientific article

Benefits and risks of bisphosphonate therapy for osteoporosis

scientific article published on 20 April 2012

Better tools for assessing osteoporosis.

scientific article published on 3 December 2012

Bisphosphonate associated osteonecrosis of the jaw.

scientific article published on March 2009

Bisphosphonate-Associated Osteonecrosis of the Jaw: Report of a Task Force of the American Society for Bone and Mineral Research

article

Bisphosphonates: mechanism of action and role in clinical practice

scientific article

Body composition during childhood and adolescence: relations to bone strength and microstructure

scientific article

Bone density and structure in healthy postmenopausal women treated with exemestane for the primary prevention of breast cancer: a nested substudy of the MAP.3 randomised controlled trial

article

Bone fragility in men--where are we?

scientific article published on August 2006

Bone growth and turnover in progesterone receptor knockout mice

scientific article published on 14 February 2008

Bone microarchitecture in ankylosing spondylitis and the association with bone mineral density, fractures, and syndesmophytes

scientific article published on January 2013

Bone microstructural changes revealed by high-resolution peripheral quantitative computed tomography imaging and elevated DKK1 and MIP-1α levels in patients with MGUS.

scientific article published on 31 October 2011

Bone strength and structural deficits in children and adolescents with a distal forearm fracture resulting from mild trauma

scientific article

Bone structure at the distal radius during adolescent growth

scientific article published on June 2009

Bone turnover across the menopause transition: correlations with inhibins and follicle-stimulating hormone

scientific article published on 31 January 2006

Bone-targeted replacement therapy for hypophosphatasia

scientific article published on 01 June 2008

Building bone to reverse osteoporosis and repair fractures

scientific article

Can vitamin D metabolite measurements facilitate a "treat-to-target" paradigm to guide vitamin D supplementation?

scientific article published on 9 January 2015

Cathepsin K Inhibitors for Osteoporosis: Biology, Potential Clinical Utility, and Lessons Learned

scientific article

Cellular senescence in bone

scientific article published on 16 January 2019

Characterization of circulating osteoblast lineage cells in humans

scientific article published on 4 January 2007

Characterization of mesenchymal progenitor cells isolated from human bone marrow by negative selection

scientific article published on 28 December 2011

Circulating Osteogenic Progenitor Cells in Mild, Moderate, and Severe Aortic Valve Stenosis

scientific article published on 01 April 2019

Circulating cells with osteogenic potential.

scientific article published on April 2006

Circulating cytokine levels in osteoporotic and normal women

scientific article published on 01 September 1994

Circulating osteoblast-lineage cells

scientific article published on 01 August 2005

Circulating osteoblast-lineage cells in humans.

scientific article

Circulating osteogenic cells: characterization and relationship to rates of bone loss in postmenopausal women

scientific article

Circulating osteogenic endothelial progenitor cell counts: new biomarker for the severity of coronary artery disease

scientific article published on 27 October 2016

Clinical Use of Quantitative Computed Tomography (QCT) of the Hip in the Management of Osteoporosis in Adults: the 2015 ISCD Official Positions-Part I.

scientific article published in July 2015

Clinical Use of Quantitative Computed Tomography-Based Advanced Techniques in the Management of Osteoporosis in Adults: the 2015 ISCD Official Positions-Part III.

scientific article

Clinical Use of Quantitative Computed Tomography-Based Finite Element Analysis of the Hip and Spine in the Management of Osteoporosis in Adults: the 2015 ISCD Official Positions-Part II.

scientific article published in July 2015

Clinical practice. Osteopenia.

scientific article published on May 2007

Clinical review 144: Estrogen and the male skeleton

scientific article

Comparison of sex steroid measurements in men by immunoassay versus mass spectroscopy and relationships with cortical and trabecular volumetric bone mineral density

scientific article published on 13 March 2008

Comparison of vertebral and femoral strength between Caucasian and Asian adults using finite element analysis of computed tomography scans

scientific article published on 04 August 2020

Comprehensive Assessment of Osteoporosis and Bone Fragility with CT Colonography.

scientific article

Concise review: Insights from normal bone remodeling and stem cell-based therapies for bone repair

scientific article published on December 2010

Contribution of In Vivo Structural Measurements and Load/Strength Ratios to the Determination of Forearm Fracture Risk in Postmenopausal Women

article by L Joseph Melton et al published 29 May 2007 in Journal of Bone and Mineral Research

Contributions of bone density and structure to fracture risk assessment in men and women

scientific article published on 02 February 2005

Coronary endothelial dysfunction in humans is associated with coronary retention of osteogenic endothelial progenitor cells

scientific article

Coronary microvascular endothelial dysfunction is an independent predictor of development of osteoporosis in postmenopausal women

scientific article

Correlates of osteoprotegerin levels in women and men.

scientific article published in May 2002

Corrigendum to 'Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease' EBioMedicine 47 (2019) 446-456

scientific article published on 23 January 2020

Corrigendum: Targeting cellular senescence prevents age-related bone loss in mice.

scientific article published in November 2017

Cortical and trabecular bone microarchitecture as an independent predictor of incident fracture risk in older women and men in the Bone Microarchitecture International Consortium (BoMIC): a prospective study

scientific article published on 28 November 2018

Cortical porosity identifies women with osteopenia at increased risk for forearm fractures.

scientific article

Cost-effective osteoporosis treatment thresholds: the United States perspective

scientific article published on 22 February 2008

Cross-sectional versus longitudinal evaluation of bone loss in men and women

scientific article

Cytokine production in the bone marrow microenvironment: failure to demonstrate estrogen regulation in early postmenopausal women

scientific article

Cytokine-specific induction of the TGF-beta inducible early gene (TIEG): regulation by specific members of the TGF-beta family

scientific article published on 01 June 2000

DHEA in elderly women and DHEA or testosterone in elderly men.

scientific article

Deletion of Estrogen Receptor Beta in Osteoprogenitor Cells Increases Trabecular but Not Cortical Bone Mass in Female Mice.

scientific article published on 29 September 2015

Determinants of Bone Material Strength and Cortical Porosity in Patients with Type 2 Diabetes Mellitus

scientific article published on 18 June 2020

Determinants of bone strength and quality in diabetes mellitus in humans

scientific article

Determinants of forearm strength in postmenopausal women.

scientific article

Development and Application of Mass Spectroscopy Assays for Nε-(1-Carboxymethyl)-L-Lysine and Pentosidine in Renal Failure and Diabetes

scientific article published on 01 May 2020

Development and characterization of a conditionally immortalized human osteoblastic cell line stably transfected with the human androgen receptor gene.

scientific article published on September 1997

Diminished bone strength is observed in adult women and men who sustained a mild trauma distal forearm fracture during childhood

scientific article

Dissection of estrogen receptor alpha signaling pathways in osteoblasts using RNA-sequencing

scientific article

Distinct effects of loss of classical estrogen receptor signaling versus complete deletion of estrogen receptor alpha on bone

scientific article

Does reduced skeletal loading account for age-related bone loss?

scientific article published on 01 December 2006

Dose-response of estrogen on bone versus the uterus in ovariectomized mice

scientific article published in October 2004

Editorial: Sex hormone binding globulin: inhibitor or facilitator (or both) of sex steroid action?

scientific article published on 01 December 2006

Effect of 2 years of testosterone replacement on insulin secretion, insulin action, glucose effectiveness, hepatic insulin clearance, and postprandial glucose turnover in elderly men.

scientific article published on 11 May 2007

Effect of EstrogenversusTestosterone on Circulating Osteoprotegerin and Other Cytokine Levels in Normal Elderly Men

Effect of blockade of TNF-alpha and interleukin-1 action on bone resorption in early postmenopausal women

scientific article published on 01 May 2007

Effect of estrogen replacement therapy on parathyroid hormone secretion in elderly postmenopausal women

scientific article published in March 2003

Effect of estrogen versus testosterone on circulating osteoprotegerin and other cytokine levels in normal elderly men.

scientific article

Effects of Age and Estrogen on Skeletal Gene Expression in Humans as Assessed by RNA Sequencing

scientific article published on 24 September 2015

Effects of Raloxifene, a Selective Estrogen Receptor Modulator, on Bone Turnover Markers and Serum Sex Steroid and Lipid Levels in Elderly Men ⬇️

scientific article published on November 1, 2001

Effects of adjuvant exemestane versus anastrozole on bone mineral density for women with early breast cancer (MA.27B): a companion analysis of a randomised controlled trial

scientific article

Effects of age and estrogen status on serum parathyroid hormone levels and biochemical markers of bone turnover in women: a population-based study

scientific article published in May 1997

Effects of age on bone mRNA levels of sclerostin and other genes relevant to bone metabolism in humans

scientific article published on 29 October 2013

Effects of bisphosphonate treatment on circulating osteogenic endothelial progenitor cells in postmenopausal women

scientific article published on 8 December 2012

Effects of body size and skeletal site on the estimated prevalence of osteoporosis in women and men.

scientific article published in January 2000

Effects of chronic estrogen treatment on modulating age-related bone loss in female mice.

scientific article

Effects of estrogen and testosterone on resting energy expenditure in older men.

scientific article

Effects of estrogen on bone mRNA levels of sclerostin and other genes relevant to bone metabolism in postmenopausal women

scientific article published on 20 December 2013

Effects of estrogen on osteoprogenitor cells and cytokines/bone-regulatory factors in postmenopausal women

scientific article

Effects of estrogen with micronized progesterone on cortical and trabecular bone mass and microstructure in recently postmenopausal women

scientific article published on 15 January 2013

Effects of gonadal and adrenal androgens in a novel androgen-responsive human osteoblastic cell line ⬇️

scientific article published on October 1, 1998

Effects of intermittent parathyroid hormone treatment on osteoprogenitor cells in postmenopausal women

scientific article

Effects of loss of classical estrogen response element signaling on bone in male mice.

scientific article published on 4 January 2007

Effects of loss of steroid receptor coactivator-1 on the skeletal response to estrogen in mice

scientific article published on 16 October 2003

Effects of parathyroid hormone treatment on circulating sclerostin levels in postmenopausal women

scientific article

Effects of physiological variations in circulating insulin levels on bone turnover in humans.

scientific article

Effects of sex and age on bone microstructure at the ultradistal radius: a population-based noninvasive in vivo assessment

scientific article

Effects of suppression of follicle-stimulating hormone secretion on bone resorption markers in postmenopausal women.

scientific article

Effects of testosterone and estradiol on cutaneous vasodilation during local warming in older men.

scientific article

Effects of the Circadian Variation in Serum Cortisol on Markers of Bone Turnover and Calcium Homeostasis in Normal Postmenopausal Women1 ⬇️

scientific article published on March 1, 1998

Emerging role of circulating calcifying cells in the bone-vascular axis

scientific article published on June 2012

Emerging therapeutic opportunities for skeletal restoration ⬇️

scientific article published on February 1, 2011

Epidemiology and clinical features of osteoporosis in young individuals

scientific article published in September 1994

Epidemiology of adrenal tumours in Olmsted County, Minnesota, USA: a population-based cohort study

scientific article published on 01 November 2020

Epidemiology of sarcopenia

scientific article published on 01 June 2000

Epidemiology of sarcopenia.

scientific article

Establishment of normative biometric data for body composition based on computed tomography in a North American cohort

scientific article published on 29 October 2020

Estrogen and fracture risk in men

scientific article published on 01 October 2008

Estrogen and the skeleton

scientific article

Estrogen inhibits Dlk1/FA1 production: a potential mechanism for estrogen effects on bone turnover.

scientific article published on October 2011

Estrogen receptor alpha and beta heterodimers exert unique effects on estrogen- and tamoxifen-dependent gene expression in human U2OS osteosarcoma cells.

scientific article

Estrogen receptor beta isoform-specific induction of transforming growth factor beta-inducible early gene-1 in human osteoblast cells: an essential role for the activation function 1 domain

scientific article published on 15 May 2008

Estrogen receptor beta: the antimechanostat?

scientific article published on 31 August 2005

Estrogen receptor isoform-specific induction of progesterone receptors in human osteoblasts

scientific article published on April 2002

Estrogen receptor isoform-specific regulation of endogenous gene expression in human osteoblastic cell lines expressing either ERalpha or ERbeta.

scientific article

Estrogen receptor isoform-specific regulation of the retinoblastoma-binding protein 1 (RBBP1) gene: roles of AF1 and enhancer elements.

scientific article

Estrogen regulation of human osteoblast function is determined by the stage of differentiation and the estrogen receptor isoform.

scientific article

Estrogen, selective estrogen receptor modulators and now mechanism-specific ligands of the estrogen or androgen receptor?

scientific article published on 01 June 2003

Estrogens and bone health in men.

scientific article

Etidronate for osteoporosis in primary biliary cirrhosis: a randomized trial

scientific article published on 01 December 2000

Evaluation of a prediction model for long-term fracture risk.

scientific article

Evaluation of cross-sectional and longitudinal changes in volumetric bone mineral density in postmenopausal women using single- versus dual-energy quantitative computed tomography

scientific article published on 25 April 2018

Evidence that type I osteoporosis results from enhanced responsiveness of bone to estrogen deficiency.

scientific article published on 18 July 2003

Examination of ERα signaling pathways in bone of mutant mouse models reveals the importance of ERE-dependent signaling

scientific article

Examination of nuclear receptor expression in osteoblasts reveals Rorβ as an important regulator of osteogenesis

scientific journal article

Expression of a potential metastasis suppressor gene (nm23) in thyroid neoplasms.

scientific article published on September 1993

Factors associated with proximal femur fracture determined in a large cadaveric cohort

scientific article published in November 2018

Fat tissue, aging, and cellular senescence

scientific article

Fatty acid metabolism in the elderly: effects of dehydroepiandrosterone and testosterone replacement in hormonally deficient men and women.

scientific article published on 30 June 2009

For estimating creatinine clearance measuring muscle mass gives better results than those based on demographics

scientific article published on 28 January 2009

Forum on aging and skeletal health: summary of the proceedings of an ASBMR workshop

scientific article published on 13 September 2011

Fracture Incidence and Characteristics in Young Adults Aged 18 to 49 Years: A Population-Based Study

scientific article published on 29 July 2017

Fracture risk after bilateral oophorectomy in elderly women.

scientific article

Fracture risk after surgery for peptic ulcer disease: a population-based cohort study

scientific article published on 01 July 1999

Fracture risk among patients with urolithiasis: a population-based cohort study

scientific article published in February 1998

Fracture risk following bilateral orchiectomy

scientific article published on 01 May 2003

Fracture risk in men with prostate cancer: a population-based study.

scientific article published in August 2011

Fracture risk in monoclonal gammopathy of undetermined significance

scientific article published on 01 January 2004

Fracture risk in primary hyperparathyroidism.

scientific article

Fracture risk in type 2 diabetes: update of a population-based study

scientific article published on August 2008

Fracture risk in women with breast cancer: a population-based study.

scientific article

Fractures following thyroidectomy in women: a population-based cohort study

scientific article published in November 2000

Global transcriptional profiling using RNA sequencing and DNA methylation patterns in highly enriched mesenchymal cells from young versus elderly women

scientific article published on 27 March 2015

Hdac3 Deficiency Increases Marrow Adiposity and Induces Lipid Storage and Glucocorticoid Metabolism in Osteochondroprogenitor Cells

scientific article published on 24 July 2015

High serum IGFBP-2 is predictive of increased bone turnover in aging men and women

scientific article published on June 2007

High-trauma fractures and bone mineral density

scientific article published in November 2007

Higher muscle protein synthesis in women than men across the lifespan, and failure of androgen administration to amend age-related decrements.

scientific article published on 30 September 2008

Hip load capacity and yield load in men and women of all ages

scientific article published on 14 March 2020

Hormonal and biochemical determinants of trabecular microstructure at the ultradistal radius in women and men.

scientific article published on 20 December 2005

Hormonal and systemic regulation of sclerostin

scientific article published on 10 December 2016

Human immunodeficiency virus envelope protein Gp120 induces proliferation but not apoptosis in osteoblasts at physiologic concentrations.

scientific article

Identification of Rorβ targets in cultured osteoblasts and in human bone

scientific article published on 11 October 2013

Identification of Senescent Cells in the Bone Microenvironment

scientific article published on 24 June 2016

Identification of multiple endocrine neoplasia, type 2 gene carriers using linkage analysis and analysis of the RET proto-oncogene

scientific article published on 01 May 1994

Identification of osteoclast-osteoblast coupling factors in humans reveals links between bone and energy metabolism

scientific article published on 07 January 2020

Idiopathic Osteoporosis—Is the Osteoblast To Blame? ⬇️

scientific article published on 01 September 1997

Implications of absolute fracture risk assessment for osteoporosis practice guidelines in the USA.

scientific article

Improved fracture risk assessment based on nonlinear micro-finite element simulations from HRpQCT images at the distal radius.

scientific article published on December 2013

In vivo assessment of bone quality in postmenopausal women with type 2 diabetes

scientific article published on April 2014

Incidence of childhood distal forearm fractures over 30 years: a population-based study

scientific article published in September 2003

Incidence of primary hyperparathyroidism in Rochester, Minnesota, 1993-2001: an update on the changing epidemiology of the disease

scientific article published on 19 September 2005

Increased Cortical Porosity and Reduced Trabecular Density Are Not Necessarily Synonymous With Bone Loss and Microstructural Deterioration.

scientific article published on 4 October 2018

Independent Roles of Estrogen Deficiency and Cellular Senescence in the Pathogenesis of Osteoporosis: Evidence in Young Adult Mice and Older Humans

scientific article published on 21 June 2019

Induction of fracture repair by mesenchymal cells derived from human embryonic stem cells or bone marrow

scientific article published on 14 June 2011

Inhibiting Cellular Senescence: A New Therapeutic Paradigm for Age-Related Osteoporosis

scientific article published on 7 February 2018

Insulin-like growth factor (IGF)-II/IGF-binding proteins in constitutionally tall children

scientific article published on 01 April 2003

Insulin-like growth factor binding protein-2: a novel regulator of skeletal gender differences?

scientific article published on 01 May 2008

Insulin-mediated FFA suppression is associated with triglyceridemia and insulin sensitivity independent of adiposity

scientific article

Interleukin-1beta and tumor necrosis factor-alpha, but not interleukin-6, stimulate osteoprotegerin ligand gene expression in human osteoblastic cells

scientific article published on September 1999

Is It Time to Stop (or Pause) Vertebral Augmentation?

scientific article published on 01 January 2019

Is Nitroglycerin a Novel and Inexpensive Treatment for Osteoporosis? ⬇️

scientific article published on February 23, 2011

Is familial hyperparathyroidism a unique disease?

scientific article published on 01 December 1997

Is vitamin D a determinant of muscle mass and strength?

scientific article published on December 2011

Isolation and characterization of human osteoblasts from needle biopsies without in vitro culture

scientific article

LPS-induced premature osteocyte senescence: Implications in inflammatory alveolar bone loss and periodontal disease pathogenesis

scientific article published on 02 January 2020

Leptin reduces ovariectomy-induced bone loss in rats

scientific article published on 01 August 2001

Leptin-central or peripheral to the regulation of bone metabolism?

scientific article published in November 2002

Long-term fracture risk among women with proven endometriosis

scientific article published on 24 October 2006

Longitudinal changes in lumbar bone mineral density distribution may increase the risk of wedge fractures.

scientific article published on 8 November 2012

Loss of ERE binding activity by estrogen receptor-alpha alters basal and estrogen-stimulated bone-related gene expression by osteoblastic cells

scientific article

Magic bullets to kill nasty osteoclasts

scientific article published on 01 August 2005

Male mice with elevated C-type natriuretic peptide-dependent guanylyl cyclase-B activity have increased osteoblasts, bone mass and bone strength

scientific article published on 13 March 2020

Male osteoporosis.

scientific article published on 17 June 2012

Managing fragility fractures during the COVID-19 pandemic

scientific article published on 11 June 2020

Mechanisms of sex steroid effects on bone.

scientific article

Mediators of the biphasic responses of bone to intermittent and continuously administered parathyroid hormone

scientific article published in May 2003

Mesenchymal stem cells for bone repair and metabolic bone diseases.

scientific article published on October 2009

Microarchitecture and Peripheral BMD are Impaired in Postmenopausal White Women With Fracture Independently of Total Hip T-Score: An International Multicenter Study

scientific article published on 28 January 2016

Minireview: The OPG/RANKL/RANK System ⬇️

scientific article published on December 1, 2001

Multicenter precision of cortical and trabecular bone quality measures assessed by high-resolution peripheral quantitative computed tomography

scientific article published on March 2013

Muscle strength in osteoporotic versus normal women

scientific article published on 01 January 1993

Mutual antagonism of estrogen receptors alpha and beta and their preferred interactions with steroid receptor coactivators in human osteoblastic cell lines.

scientific article

Mutual enhancement of differentiation of osteoblasts and osteocytes occurs through direct cell-cell contact

scientific article published on November 2014

Myostatin as a mediator of sarcopenia versus homeostatic regulator of muscle mass: insights using a new mass spectrometry-based assay

scientific article published on 15 July 2015

Native osteoprotegerin gene transfer inhibits the development of murine osteolytic bone disease induced by tumor xenografts.

scientific article published on April 2004

New Insights Into Androgen and Estrogen Receptor Regulation of the Male Skeleton.

scientific article published on July 2015

Nonoxidative free fatty acid disposal is greater in young women than men.

scientific article published on December 2010

Novel anthropomorphic hip phantom corrects systemic interscanner differences in proximal femoral vBMD

scientific article published on December 2014

Odanacatib: Location and timing are everything ⬇️

scientific article published on 01 March 2012

Oestrogen, bones and men: when testosterone just isn't enough.

scientific article

Operator variability in scan positioning is a major component of HR-pQCT precision error and is reduced by standardized training

scientific article published on 30 July 2016

Oral bisphosphonate-induced osteonecrosis: risk factors, prediction of risk using serum CTX testing, prevention, and treatment

scientific article published in June 2008

Osteocalcin expression by circulating endothelial progenitor cells in patients with coronary atherosclerosis

scientific article published on October 2008

Osteocalcin positive CD133+/CD34-/KDR+ progenitor cells as an independent marker for unstable atherosclerosis

scientific article

Osteoclast TGF-β Receptor Signaling Induces Wnt1 Secretion and Couples Bone Resorption to Bone Formation.

scientific article published on 24 June 2015

Osteogenic monocytes within the coronary circulation and their association with plaque vulnerability in patients with early atherosclerosis

scientific article

Osteoporosis and Hip Fracture Risk From Routine Computed Tomography Scans: The Fracture, Osteoporosis, and CT Utilization Study (FOCUS).

scientific article published on 17 April 2018

Osteoporosis assessment by whole body region vs. site-specific DXA

scientific article published on 06 April 2005

Osteoporosis detection in postmenopausal women using axial transmission multi-frequency bone ultrasonometer: clinical findings

scientific article

Osteoporosis in men

Osteoporosis in men--consensus is premature.

scientific article published on 27 May 2004

Osteoporosis update from the 2010 santa fe bone symposium

scientific article published on January 2011

Osteoporosis: gender differences and similarities

scientific article

Osteoporosis: now and the future

scientific article published on 28 March 2011

Osteoprotection Through the Deletion of the Transcription Factor Rorβ in Mice

scientific article published on 5 December 2017

Osteoprotegerin production by human osteoblast lineage cells is stimulated by vitamin D, bone morphogenetic protein-2, and cytokines

scientific article published on September 1998

Parathyroid Hormone plus Alendronate — A Combination That Does Not Add Up ⬇️

scientific article published on September 20, 2003

Pathogenesis of Age-Related Bone Loss in Humans ⬇️

scientific article published on August 24, 2012

Pathophysiologic importance of visceral adipose tissue in women with heart failure and preserved ejection fraction

scientific article published on 23 November 2020

Patients with an HbA1c in the prediabetic and diabetic range have higher numbers of circulating cells with osteogenic and endothelial progenitor cell markers

scientific article

Periodontal Disease and Senescent Cells: New Players for an Old Oral Health Problem?

scientific article published on 09 October 2020

Placebo-Controlled Trials in Osteoporosis — Proceeding with Caution ⬇️

scientific article published on September 30, 2010

Polyphenol-rich cranberry juice has a neutral effect on endothelial function but decreases the fraction of osteocalcin-expressing endothelial progenitor cells

scientific article published on 02 March 2012

Population-based analysis of the relationship of whole bone strength indices and fall-related loads to age- and sex-specific patterns of hip and wrist fractures

scientific article

Population-based study of age and sex differences in bone volumetric density, size, geometry, and structure at different skeletal sites

scientific article

Posterior single-stepping thresholds are prospectively related to falls in older women

scientific article published on 14 February 2020

Potential Extensions of the US FRAX Algorithm.

scientific article

Potential role of pancreatic and enteric hormones in regulating bone turnover.

scientific article

Primary hyperparathyroidism and the risk of fracture: a population-based study

scientific article published on 01 October 1999

Primary osteoporosis in men: role of sex steroid deficiency.

scientific article

Proceedings of the 2018 Santa Fe Bone Symposium: Advances in the Management of Osteoporosis

scientific article published on 22 September 2018

Prospective randomized study of effects of unopposed estrogen replacement therapy on markers of coagulation and inflammation in postmenopausal women

scientific article

Proximal femoral density distribution and structure in relation to age and hip fracture risk in women

scientific article published on March 2013

Quantification of GDF11 and Myostatin in Human Aging and Cardiovascular Disease.

scientific article published on June 2016

Re: "The 3.6 kb DNA fragment from the rat Col1a1 gene promoter drives the expression of genes in both osteoblast and osteoclast lineage cells" by Boban et al. (Bone 39:1302-1312, 2006).

scientific article published on 23 February 2007

Receptor activator of nuclear factor kappaB ligand and osteoprotegerin regulation of bone remodeling in health and disease.

scientific article published on 5 December 2007

Reducing Senescent Cell Burden in Aging and Disease

scientific article published on 17 April 2020

Regarding "True Gold or Pyrite: A Review of Reference Point Indentation for Assessing Bone Mechanical Properties In Vivo".

scientific article published on 31 August 2015

Regulation of bone formation by osteoclasts involves Wnt/BMP signaling and the chemokine sphingosine-1-phosphate.

scholarly article

Regulation of bone turnover by sex steroids in men

scientific article published on May 2008

Regulation of circulating sclerostin levels by sex steroids in women and in men.

scientific article

Regulation of osteoclastogenesis and RANK expression by TGF-beta1.

scientific article

Relation of age, gender, and bone mass to circulating sclerostin levels in women and men.

scientific article

Relation of serum serotonin levels to bone density and structural parameters in women

scientific article

Relation of vertebral deformities to bone density, structure, and strength

scientific article

Relationship between body composition and bone mass in women

scientific article published on June 1996

Relationship of adiposity to bone volumetric density and microstructure in men and women across the adult lifespan

scientific article published on 18 February 2013

Relationship of age to bone microstructure independent of areal bone mineral density

scientific article published on March 2012

Relationship of bone turnover to bone density and fractures

scientific article

Relationship of estrogen receptor genotypes to bone mineral density and to rates of bone loss in men.

scientific article published in April 2004

Relationship of femoral neck areal bone mineral density to volumetric bone mineral density, bone size, and femoral strength in men and women

scientific article published on 5 November 2011

Relationship of intestinal calcium absorption to 1,25-dihydroxyvitamin D [1,25(OH)2D] levels in young versus elderly women: evidence for age-related intestinal resistance to 1,25(OH)2D action

scientific article published in November 2000

Relationship of serum leptin levels with body composition and sex steroid and insulin levels in men and women

scientific article published on 01 October 2000

Relationship of serum sex steroid levels and bone turnover markers with bone mineral density in men and women: a key role for bioavailable estrogen

scientific article published in July 1998

Relationship of serum sex steroid levels to longitudinal changes in bone density in young versus elderly men.

scientific article

Relationship of sympathetic activity to bone microstructure, turnover, and plasma osteopontin levels in women

scientific article

Relationship of testosterone and osteocalcin levels during growth

scientific article published in September 2011

Relationship of volumetric BMD and structural parameters at different skeletal sites to sex steroid levels in men.

scientific article published on 20 December 2004

Relationship of volumetric bone density and structural parameters at different skeletal sites to sex steroid levels in women

scientific article

Relative contributions of testosterone and estrogen in regulating bone resorption and formation in normal elderly men

scientific article published on December 2000

Relative influence of physical activity, muscle mass and strength on bone density

scientific article published on 01 January 2000

Response to Stoecker et al.

scientific article published on 31 March 2017

Response to Wnt Signaling Pathways

scientific article published on 14 September 2015

Robust QCT/FEA models of proximal femur stiffness and fracture load during a sideways fall on the hip.

scientific article published on 29 October 2010

Role of Low Levels of Endogenous Estrogen in Regulation of Bone Resorption in Late Postmenopausal Women ⬇️

scientific article published on January 1, 2002

Role of RANK ligand in mediating increased bone resorption in early postmenopausal women

scientific article

Role of calcium intake in modulating age-related increases in parathyroid function and bone resorption

scientific article published on 01 May 1996

Role of circulating osteogenic progenitor cells in calcific aortic stenosis

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Role of extracellular matrix in insulin-like growth factor (IGF) binding protein-2 regulation of IGF-II action in normal human osteoblasts

scientific article published in December 2003

Role of parathyroid hormone in mediating age-related changes in bone resorption in men.

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Role of serum leptin, insulin, and estrogen levels as potential mediators of the relationship between fat mass and bone mineral density in men versus women

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SAT-366 The Impact of Mild Autonomous Cortisol Secretion on Bone Metabolism

Sclerostin is expressed in osteoclasts from aged mice and reduces osteoclast-mediated stimulation of mineralization.

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Sclerostin levels during growth in children.

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Secondary Fracture Prevention: Consensus Clinical Recommendations From a Multistakeholder Coalition

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Secondary Fracture Prevention: Consensus Clinical Recommendations from a Multistakeholder Coalition

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Secondary Fracture Prevention: Consensus Clinical Recommendations from a Multistakeholder Coalition

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Secondary osteoporosis and the risk of distal forearm fractures in men and women.

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Secondary osteoporosis and the risk of vertebral deformities in women

scientific article published on 01 January 1999

Senescent cells exacerbate chronic inflammation and contribute to periodontal disease progression in old mice

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Senolytic Drugs: Reducing Senescent Cell Viability to Extend Health Span

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Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease

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Senolytics improve physical function and increase lifespan in old age

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Senolytics reduce coronavirus-related mortality in old mice

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Serum biomarker profile associated with high bone turnover and BMD in postmenopausal women

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Sex steroids and the construction and conservation of the adult skeleton

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Sex- and age-related differences in bone microarchitecture in men relative to women assessed by high-resolution peripheral quantitative computed tomography.

scientific article published on 16 February 2012

Skeletal Metabolism, Fracture Risk, and Fracture Outcomes in Type 1 and Type 2 Diabetes.

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Skeletal changes through the lifespan--from growth to senescence

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Skeletal consequences of deletion of steroid receptor coactivator-2/transcription intermediary factor-2.

scientific article published on 07 May 2009

Skeletal effects of estrogen are mediated by opposing actions of classical and nonclassical estrogen receptor pathways

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Skeletal muscle mass is associated with bone geometry and microstructure and serum insulin-like growth factor binding protein-2 levels in adult women and men.

scientific article published on October 2012

Skeletal stem/osteoprogenitor cells: current concepts, alternate hypotheses, and relationship to the bone remodeling compartment

scientific article published on February 2008

Sphingosine 1-Phosphate (S1P) Receptors 1 and 2 Coordinately Induce Mesenchymal Cell Migration through S1P Activation of Complementary Kinase Pathways* ⬇️

scientific article published on January 7, 2013

Statistical Parametric Mapping of HR-pQCT Images: A Tool for Population-Based Local Comparisons of Micro-Scale Bone Features

scientific article published on 9 November 2016

Structural determinants of vertebral fracture risk

scientific article published on 01 December 2007

Structural patterns of the proximal femur in relation to age and hip fracture risk in women

scientific article published on 25 August 2013

Subcutaneous administration of insulin-like growth factor (IGF)-II/IGF binding protein-2 complex stimulates bone formation and prevents loss of bone mineral density in a rat model of disuse osteoporosis

scientific article published in June 2002

Surrogates for fracture endpoints in clinical trials

scientific article published on 01 June 2003

Survival after the diagnosis of hyperparathyroidism: a population-based study

scientific article published on 01 February 1998

Sympathetic β1-adrenergic signaling contributes to regulation of human bone metabolism

scientific article published on 02 October 2018

TGF-β induces Wnt10b in osteoclasts from female mice to enhance coupling to osteoblasts

scientific article published on 16 July 2013

TGF-β mediates suppression of adipogenesis by estradiol through connective tissue growth factor induction

scientific article published on 8 November 2011

Targeted Reduction of Senescent Cell Burden Alleviates Focal Radiotherapy-Related Bone Loss

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Targeting bone remodeling for the treatment of osteoporosis: summary of the proceedings of an ASBMR workshop

scientific article published on 01 March 2009

Targeting cellular senescence prevents age-related bone loss in mice.

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Technical note: Recommendations for a standard procedure to assess cortical bone at the tissue-level in vivo using impact microindentation

scientific article published on 26 July 2016

Testosterone: more is not always better

scientific article published in December 2009

The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.

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The Impact of Mild Autonomous Cortisol Secretion on Bone Turnover Markers

scientific article published on 01 May 2020

The Limited Clinical Utility of Testosterone, Estradiol, and Sex Hormone Binding Globulin Measurements in the Prediction of Fracture Risk and Bone Loss in Older Men.

scientific article published on 18 October 2016

The anti-androgen hydroxyflutamide and androgens inhibit interleukin-6 production by an androgen-responsive human osteoblastic cell line.

scientific article published on August 1999

The assembly of the adult skeleton during growth and maturation: implications for senile osteoporosis

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The bone and beyond: a shift in calcium

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The circumstances, orientations, and impact locations of falls in community-dwelling older women.

scientific article published on 21 July 2017

The clinical diagnosis of osteoporosis: a position statement from the National Bone Health Alliance Working Group.

scientific article published on 28 February 2014

The endogenous selective estrogen receptor modulator 27-hydroxycholesterol is a negative regulator of bone homeostasis.

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The impact of the new National Bone Health Alliance (NBHA) diagnostic criteria on the prevalence of osteoporosis in the USA.

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The microbiome adds to the complexity of parathyroid hormone action on bone

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The oxysterol, 27-hydroxycholesterol, links cholesterol metabolism to bone homeostasis through its actions on the estrogen and liver X receptors

scientific article published on 20 September 2011

The relationships between compensatory stepping thresholds and measures of gait, standing postural control, strength, and balance confidence in older women

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The rise and fall of primary hyperparathyroidism: a population-based study in Rochester, Minnesota, 1965-1992.

scientific article published in March 1997

The role of cellular senescence in ageing and endocrine disease

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The role of estrogens in men and androgens in women.

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The role of the immune system in the pathophysiology of osteoporosis

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The unitary model for estrogen deficiency and the pathogenesis of osteoporosis: is a revision needed?

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Three-dimensional structural analysis of the proximal femur in an age-stratified sample of women.

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Towards a diagnostic and therapeutic consensus in male osteoporosis

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Trabecular bone deficits among Vietnamese immigrants

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Transforming growth factor beta 1 induces CXCL16 and leukemia inhibitory factor expression in osteoclasts to modulate migration of osteoblast progenitors.

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Treatment-Related Changes in Bone Turnover and Fracture Risk Reduction in Clinical Trials of Anti-Resorptive Drugs: A Meta-Regression

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Treatment-Related Changes in Bone Turnover and Fracture Risk Reduction in Clinical Trials of Antiresorptive Drugs: Proportion of Treatment Effect Explained

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Treatment-related changes in bone mineral density as a surrogate biomarker for fracture risk reduction: meta-regression analyses of individual patient data from multiple randomised controlled trials

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Trends in fracture incidence: a population-based study over 20 years.

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Two years of treatment with dehydroepiandrosterone does not improve insulin secretion, insulin action, or postprandial glucose turnover in elderly men or women

scientific article published in March 2007

Unsupervised machine learning for the discovery of latent disease clusters and patient subgroups using electronic health records

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Update in male osteoporosis

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Update on Estrogens and the Skeleton ⬇️

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Use of renal function measurements for assessing fracture risk in postmenopausal women.

scientific article published on November 2008

Use of site-specific antibodies to characterize the circulating form of big insulin-like growth factor II in patients with hepatitis C-associated osteosclerosis

scientific article published on 01 August 2002

Validation of a CT-derived method for osteoporosis screening in IBD patients undergoing contrast-enhanced CT enterography.

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Validation of a novel, rapid, high precision sclerostin assay not confounded by sclerostin fragments

scientific article published on 14 March 2018

Voxel size dependency, reproducibility and sensitivity of an in vivo bone loading estimation algorithm.

scientific article published on January 2016

What Accounts for Rib Fractures in Older Adults? ⬇️

scientific article published on October 19, 2011

What Do We Tell Our Patients about Calcium and Vitamin D Supplementation? ⬇️

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Wnt Signaling Inhibits Osteoclast Differentiation by Activating Canonical and Noncanonical cAMP/PKA Pathways

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Wnt Signaling Inhibits Osteoclast Differentiation by Activating Canonical and Noncanonical cAMP/PKA Pathways

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Wnt10b activates the Wnt, notch, and NFκB pathways in U2OS osteosarcoma cells.

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miR-219a-5p Regulates Rorβ During Osteoblast Differentiation and in Age-related Bone Loss

scientific article published on 15 October 2018

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