List of works - Yen-Hua Huang

A novel quantitative kinase assay using bacterial surface display and flow cytometry

scientific article (publication date: 2013)

Anticancer and toxic properties of cyclotides are dependent on phosphatidylethanolamine phospholipid targeting

scientific article

Backbone cyclization of analgesic conotoxin GeXIVA facilitates direct folding of the ribbon isomer

scientific article published on 28 August 2017

Cell Membrane Composition Drives Selectivity and Toxicity of Designed Cyclic Helix-Loop-Helix Peptides with Cell Penetrating and Tumor Suppressor Properties

scientific article published on 21 August 2019

Characterization of Tachyplesin Peptides and Their Cyclized Analogues to Improve Antimicrobial and Anticancer Properties ⬇️

scientific article published on 26 August 2019

Circular Permutation of the Native Enzyme-Mediated Cyclization Position in Cyclotides

scientific article published on 30 March 2020

Cyclotide interactions with the nematode external surface.

scientific article

Cyclotides Suppress Human T-Lymphocyte Proliferation by an Interleukin 2-Dependent Mechanism

scientific article (publication date: 2013)

Cyclotides: natural, circular plant peptides that possess significant activity against gastrointestinal nematode parasites of sheep.

scientific article published on 22 April 2008

Decoding the membrane activity of the cyclotide kalata B1: the importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities

scientific article

Design and characterization of novel antimicrobial peptides, R-BP100 and RW-BP100, with activity against Gram-negative and Gram-positive bacteria.

scientific article

Design of substrate-based BCR-ABL kinase inhibitors using the cyclotide scaffold

scientific article

Development of cell-penetrating peptide-based drug leads to inhibit MDMX:p53 and MDM2:p53 interactions

scientific article published on 10 June 2016

Discovery and mechanistic studies of cytotoxic cyclotides from the medicinal herb Hybanthus enneaspermus

scientific article published on 15 May 2020

Effects of arginine 10 to lysine substitution on ω-conotoxin CVIE and CVIF block of Cav2.2 channels.

scientific article

Enhanced Activity against Multidrug-Resistant Bacteria through Coapplication of an Analogue of Tachyplesin I and an Inhibitor of the QseC/B Signaling Pathway

scientific article published on 14 February 2020

Evaluation of the <i>in Vivo</i> Aphrodisiac Activity of a Cyclotide Extract from <i>Hybanthus enneaspermus</i>

scientific article published on 09 December 2020

Fmoc-based synthesis of disulfide-rich cyclic peptides

scientific article published on 11 June 2014

High-affinity cyclic peptide matriptase inhibitors

scientific article published on 2 April 2013

Identification and characterization of a new family of cell-penetrating peptides: cyclic cell-penetrating peptides

scientific article

Inhibition of tau aggregation using a naturally-occurring cyclic peptide scaffold.

scientific article published on 8 January 2016

Lengths of the C-Terminus and Interconnecting Loops Impact Stability of Spider-Derived Gating Modifier Toxins

scientific article published on 12 August 2017

Optimization of the cyclotide framework to improve cell penetration properties

scientific article

Phosphatidylethanolamine binding is a conserved feature of cyclotide-membrane interactions

scientific article

Redesigned Spider Peptide with Improved Antimicrobial and Anticancer Properties

scientific article published on 25 July 2017

Semienzymatic Cyclization of Disulfide-rich Peptides Using Sortase A

scientific article published on 7 March 2014

Structural and functional characterization of chimeric cyclotides from the Möbius and trypsin inhibitor subfamilies

scientific article published on 3 August 2016

Synthesis, Racemic X-ray Crystallographic, and Permeability Studies of Bioactive Orbitides from Jatropha Species

article

The Prototypic Cyclotide Kalata B1 Has a Unique Mechanism of Entering Cells

scientific article published on 11 August 2015

The antimicrobial activity of Sub3 is dependent on membrane binding and cell-penetrating ability

scientific article

The biological activity of the prototypic cyclotide kalata b1 is modulated by the formation of multimeric pores

scientific article

Understanding the Diversity and Distribution of Cyclotides from Plants of Varied Genetic Origin

scientific article

List of works by Yen-Hua Huang

A novel quantitative kinase assay using bacterial surface display and flow cytometry

Anticancer and toxic properties of cyclotides are dependent on phosphatidylethanolamine phospholipid targeting

Backbone cyclization of analgesic conotoxin GeXIVA facilitates direct folding of the ribbon isomer

Cell Membrane Composition Drives Selectivity and Toxicity of Designed Cyclic Helix-Loop-Helix Peptides with Cell Penetrating and Tumor Suppressor Properties

Characterization of Tachyplesin Peptides and Their Cyclized Analogues to Improve Antimicrobial and Anticancer Properties ⬇️

Circular Permutation of the Native Enzyme-Mediated Cyclization Position in Cyclotides

Cyclotide interactions with the nematode external surface.

Cyclotides Suppress Human T-Lymphocyte Proliferation by an Interleukin 2-Dependent Mechanism

Cyclotides: natural, circular plant peptides that possess significant activity against gastrointestinal nematode parasites of sheep.

Decoding the membrane activity of the cyclotide kalata B1: the importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities

Design and characterization of novel antimicrobial peptides, R-BP100 and RW-BP100, with activity against Gram-negative and Gram-positive bacteria.

Design of substrate-based BCR-ABL kinase inhibitors using the cyclotide scaffold

Development of cell-penetrating peptide-based drug leads to inhibit MDMX:p53 and MDM2:p53 interactions

Discovery and mechanistic studies of cytotoxic cyclotides from the medicinal herb Hybanthus enneaspermus

Effects of arginine 10 to lysine substitution on ω-conotoxin CVIE and CVIF block of Cav2.2 channels.

Enhanced Activity against Multidrug-Resistant Bacteria through Coapplication of an Analogue of Tachyplesin I and an Inhibitor of the QseC/B Signaling Pathway

Evaluation of the <i>in Vivo</i> Aphrodisiac Activity of a Cyclotide Extract from <i>Hybanthus enneaspermus</i>

Fmoc-based synthesis of disulfide-rich cyclic peptides

High-affinity cyclic peptide matriptase inhibitors

Identification and characterization of a new family of cell-penetrating peptides: cyclic cell-penetrating peptides

Inhibition of tau aggregation using a naturally-occurring cyclic peptide scaffold.

Lengths of the C-Terminus and Interconnecting Loops Impact Stability of Spider-Derived Gating Modifier Toxins

Optimization of the cyclotide framework to improve cell penetration properties

Phosphatidylethanolamine binding is a conserved feature of cyclotide-membrane interactions

Redesigned Spider Peptide with Improved Antimicrobial and Anticancer Properties

Semienzymatic Cyclization of Disulfide-rich Peptides Using Sortase A

Structural and functional characterization of chimeric cyclotides from the Möbius and trypsin inhibitor subfamilies

Synthesis, Racemic X-ray Crystallographic, and Permeability Studies of Bioactive Orbitides from Jatropha Species

The Prototypic Cyclotide Kalata B1 Has a Unique Mechanism of Entering Cells

The antimicrobial activity of Sub3 is dependent on membrane binding and cell-penetrating ability

The biological activity of the prototypic cyclotide kalata b1 is modulated by the formation of multimeric pores

Understanding the Diversity and Distribution of Cyclotides from Plants of Varied Genetic Origin