List of works - Han-Yu Shih

A discrete chromatin loop in the mouse Tcra-Tcrd locus shapes the TCRδ and TCRα repertoires

scientific article

Asymmetric Action of STAT Transcription Factors Drives Transcriptional Outputs and Cytokine Specificity.

scientific article

BACH2 regulates CD8(+) T cell differentiation by controlling access of AP-1 factors to enhancers

scientific article published on 09 May 2016

Chromatin architecture, CCCTC-binding factor, and V(D)J recombination: managing long-distance relationships at antigen receptor loci.

scientific article published on May 2013

Commensal-specific T cell plasticity promotes rapid tissue adaptation to injury

scientific article published on 06 December 2018

Developmental Acquisition of Regulomes Underlies Innate Lymphoid Cell Functionality

scientific article published on 04 May 2016

Epigenomic Views of Innate Lymphoid Cells

scientific article published on 13 November 2017

Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions.

scientific article

Helper T cell plasticity: impact of extrinsic and intrinsic signals on transcriptomes and epigenomes

scientific article

Histone deacetylase 1 (HDAC1): A key player of T cell-mediated arthritis

scientific article published on 26 December 2019

Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium

scientific article published on 31 January 2019

IL-7 coordinates proliferation, differentiation and Tcra recombination during thymocyte β-selection.

scientific article

MicroRNA-221 and -222 modulate intestinal inflammatory Th17 cell response as negative feedback regulators downstream of interleukin-23

scientific article published on 02 March 2021

NCR+ ILC3 maintain larger STAT4 reservoir via T-BET to regulate type 1 features upon IL-23 stimulation in mice

scientific article published on 16 April 2018

Neuropeptide CGRP Limits Group 2 Innate Lymphoid Cell Responses and Constrains Type 2 Inflammation

scientific article published on 25 July 2019

Orchestrating T-cell receptor α gene assembly through changes in chromatin structure and organization.

scientific article published on April 2011

Regulation of TCRβ Allelic Exclusion by Gene Segment Proximity and Accessibility ⬇️

scientific article published on November 11, 2011

Restoration of the type I IFN-IL-1 balance through targeted blockade of PTGER4 inhibits autoimmunity in NOD mice

scientific article published on 8 February 2018

Retinoic Acid Receptor Alpha Represses a Th9 Transcriptional and Epigenomic Program to Reduce Allergic Pathology

scientific article published on 01 January 2019

Shared and restricted T-cell receptor use is crucial for carbamazepine-induced Stevens-Johnson syndrome

scientific article published on 14 September 2011

Signal transducer and activator of transcription 5 (STAT5) paralog dose governs T cell effector and regulatory functions.

scientific article published on 21 March 2016

Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection

scientific article published on 17 June 2019

Tcra gene recombination is supported by a Tcra enhancer- and CTCF-dependent chromatin hub.

scientific article

The Histone Variant MacroH2A1.2 Is Necessary for the Activation of Muscle Enhancers and Recruitment of the Transcription Factor Pbx1.

scientific article published on 27 January 2016

The Magnitude of IFN-γ Responses Is Fine-Tuned by DNA Architecture and the Non-coding Transcript of Ifng-as1

scientific article published on 31 July 2019

The Transcription Factor T-bet Limits Amplification of Type I IFN Transcriptome and Circuitry in T Helper 1 Cells.

scientific article published on 8 June 2017

Transcriptional and epigenetic networks of helper T and innate lymphoid cells.

scientific article

Variable Extent of Lineage-Specificity and Developmental Stage-Specificity of Cohesin and CCCTC-Binding Factor Binding Within the Immunoglobulin and T Cell Receptor Loci.

scientific article published on 8 March 2018

List of works by Han-Yu Shih

A discrete chromatin loop in the mouse Tcra-Tcrd locus shapes the TCRδ and TCRα repertoires

Asymmetric Action of STAT Transcription Factors Drives Transcriptional Outputs and Cytokine Specificity.

BACH2 regulates CD8(+) T cell differentiation by controlling access of AP-1 factors to enhancers

Chromatin architecture, CCCTC-binding factor, and V(D)J recombination: managing long-distance relationships at antigen receptor loci.

Commensal-specific T cell plasticity promotes rapid tissue adaptation to injury

Developmental Acquisition of Regulomes Underlies Innate Lymphoid Cell Functionality

Epigenomic Views of Innate Lymphoid Cells

Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions.

Helper T cell plasticity: impact of extrinsic and intrinsic signals on transcriptomes and epigenomes

Histone deacetylase 1 (HDAC1): A key player of T cell-mediated arthritis

Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium

IL-7 coordinates proliferation, differentiation and Tcra recombination during thymocyte β-selection.

MicroRNA-221 and -222 modulate intestinal inflammatory Th17 cell response as negative feedback regulators downstream of interleukin-23

NCR+ ILC3 maintain larger STAT4 reservoir via T-BET to regulate type 1 features upon IL-23 stimulation in mice

Neuropeptide CGRP Limits Group 2 Innate Lymphoid Cell Responses and Constrains Type 2 Inflammation

Orchestrating T-cell receptor α gene assembly through changes in chromatin structure and organization.

Regulation of TCRβ Allelic Exclusion by Gene Segment Proximity and Accessibility ⬇️

Restoration of the type I IFN-IL-1 balance through targeted blockade of PTGER4 inhibits autoimmunity in NOD mice

Retinoic Acid Receptor Alpha Represses a Th9 Transcriptional and Epigenomic Program to Reduce Allergic Pathology

Shared and restricted T-cell receptor use is crucial for carbamazepine-induced Stevens-Johnson syndrome

Signal transducer and activator of transcription 5 (STAT5) paralog dose governs T cell effector and regulatory functions.

Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection

Tcra gene recombination is supported by a Tcra enhancer- and CTCF-dependent chromatin hub.

The Histone Variant MacroH2A1.2 Is Necessary for the Activation of Muscle Enhancers and Recruitment of the Transcription Factor Pbx1.

The Magnitude of IFN-γ Responses Is Fine-Tuned by DNA Architecture and the Non-coding Transcript of Ifng-as1

The Transcription Factor T-bet Limits Amplification of Type I IFN Transcriptome and Circuitry in T Helper 1 Cells.

Transcriptional and epigenetic networks of helper T and innate lymphoid cells.

Variable Extent of Lineage-Specificity and Developmental Stage-Specificity of Cohesin and CCCTC-Binding Factor Binding Within the Immunoglobulin and T Cell Receptor Loci.