List of works by Priscille Brodin

2-Carboxyquinoxalines kill mycobacterium tuberculosis through noncovalent inhibition of DprE1

scientific article

A Bacterial Toxin with Analgesic Properties: Hyperpolarization of DRG Neurons by Mycolactone.

scientific article published on 18 July 2017

A Truncated HIV-1 Tat Protein Basic Domain Rapidly Translocates through the Plasma Membrane and Accumulates in the Cell Nucleus

article

A combination screening to identify enhancers of para-aminosalicylic acid against Mycobacterium tuberculosis

scientific article published on 04 April 2022

A fast, fully automated cell segmentation algorithm for high-throughput and high-content screening

scientific article

A fragment merging approach towards the development of small molecule inhibitors of Mycobacterium tuberculosis EthR for use as ethionamide boosters

scientific article published on 25 January 2016

A microscopic phenotypic assay for the quantification of intracellular mycobacteria adapted for high-throughput/high-content screening

scientific article published on 17 January 2014

A new evolutionary scenario for the Mycobacterium tuberculosis complex

scientific article

A novel codrug made of the combination of ethionamide and its potentiating booster: synthesis, self-assembly into nanoparticles and antimycobacterial evaluation

scientific article published on 10 May 2019

A novel specific edge effect correction method for RNA interference screenings

scientific article published on 26 November 2011

Aconitate decarboxylase 1 participates in the control of pulmonary Brucella infection in mice

scientific article published on 15 September 2021

An increase in antimycobacterial Th1-cell responses by prime-boost protocols of immunization does not enhance protection against tuberculosis

scientific article

Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis

scientific article published in 2011

ArfGAP1 restricts Mycobacterium tuberculosis entry by controlling the actin cytoskeleton.

scientific article published on 15 November 2017

Automated high-throughput siRNA transfection in raw 264.7 macrophages: a case study for optimization procedure

scientific article

Bacterial artificial chromosome-based comparative genomic analysis identifies Mycobacterium microti as a natural ESAT-6 deletion mutant

scientific article

Benzofuro[3,2-f][1]benzopyrans: A new class of antitubercular agents

scientific article published on 17 April 2006

Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis

scientific journal article

CD8+-T-cell responses of Mycobacterium-infected mice to a newly identified major histocompatibility complex class I-restricted epitope shared by proteins of the ESAT-6 family

scientific journal article

Cell Microbiology Interview

scientific article published on 04 November 2020

Cell envelope protein PPE68 contributes to Mycobacterium tuberculosis RD1 immunogenicity independently of a 10-kilodalton culture filtrate protein and ESAT-6.

scientific article published on April 2004

Clofazimine encapsulation in nanoporous silica particles for the oral treatment of antibiotic-resistant Mycobacterium tuberculosis infections

scientific article published on 24 March 2017

Combination therapy for tuberculosis treatment: pulmonary administration of ethionamide and booster co-loaded nanoparticles

scientific article

Compartmentalized Encapsulation of Two Antibiotics in Porous Nanoparticles: an Efficient Strategy to Treat Intracellular Infections

Control of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP

scientific journal article

Could Mycolactone Inspire New Potent Analgesics? Perspectives and Pitfalls

scientific article published on 04 September 2019

Cyclipostins and Cyclophostin analogs as promising compounds in the fight against tuberculosis.

scientific article published on 18 September 2017

Cyclodextrin-based nanocarriers containing a synergic drug combination: A potential formulation for pulmonary administration of antitubercular drugs

scientific article published on 15 May 2017

Cytosolic access of Mycobacterium tuberculosis: critical impact of phagosomal acidification control and demonstration of occurrence in vivo

scientific article published on 6 February 2015

Dehydrojuncusol, a Natural Phenanthrene Compound Extracted from Juncus maritimus, Is a New Inhibitor of Hepatitis C Virus RNA Replication

scientific article published on 01 May 2019

Determinants of Mg2+-dependent activities of recombinant human immunodeficiency virus type 1 integrase

scientific article published in August 2000

Disruption of HIV-1 integrase-DNA complexes by short 6-oxocytosine-containing oligonucleotides

scientific article

Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence

scientific article

ESAT-6 from Mycobacterium tuberculosis dissociates from its putative chaperone CFP-10 under acidic conditions and exhibits membrane-lysing activity

scientific article published on 8 June 2007

ESAT-6 proteins: protective antigens and virulence factors?

scientific article

Enhanced protection against tuberculosis by vaccination with recombinant Mycobacterium microti vaccine that induces T cell immunity against region of difference 1 antigens

scientific article published on 4 June 2004

Ethionamide boosters. 2. Combining bioisosteric replacement and structure-based drug design to solve pharmacokinetic issues in a series of potent 1,2,4-oxadiazole EthR inhibitors

scientific article

Ethionamide boosters: synthesis, biological activity, and structure-activity relationships of a series of 1,2,4-oxadiazole EthR inhibitors

scientific article published on April 2011

Evaluation of vaccines in the EU TB Vaccine Cluster using a guinea pig aerosol infection model of tuberculosis

scientific article published on 20 January 2005

Fragment-Based Optimized EthR Inhibitors with in Vivo Ethionamide Boosting Activity

scientific article published on 02 March 2020

Fragment-Sized EthR Inhibitors Exhibit Exceptionally Strong Ethionamide Boosting Effect in Whole-Cell Mycobacterium tuberculosis Assays

scientific article

Functional analysis of early secreted antigenic target-6, the dominant T-cell antigen of Mycobacterium tuberculosis, reveals key residues involved in secretion, complex formation, virulence, and immunogenicity

scientific article published on 27 July 2005

Functional characterization of the Mycobacterium tuberculosis serine/threonine kinase PknJ

scientific journal article

Genome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolism

scientific article

Heparin-Binding Hemagglutinin Adhesin (HBHA) Is Involved in Intracytosolic Lipid Inclusions Formation in Mycobacteria

scientific article published on 24 September 2018

High content phenotypic cell-based visual screen identifies Mycobacterium tuberculosis acyltrehalose-containing glycolipids involved in phagosome remodeling

scientific journal article

High content screening identifies decaprenyl-phosphoribose 2' epimerase as a target for intracellular antimycobacterial inhibitors

scientific article

High content screening in chemical biology: overview and main challenges

scientific article

High frequency of CD4+ T cells specific for the TB10.4 protein correlates with protection against Mycobacterium tuberculosis infection

scientific article

High-content imaging of Mycobacterium tuberculosis-infected macrophages: an in vitro model for tuberculosis drug discovery

scientific article

High-content screening in infectious diseases

scientific article published on 20 June 2011

High-content screening technology combined with a human granuloma model as a new approach to evaluate the activities of drugs against Mycobacterium tuberculosis.

scientific article published on 27 October 2014

Host-directed therapies offer novel opportunities for the fight against tuberculosis

scientific article

Host-pathogen systems for early drug discovery against tuberculosis

scientific article

How can nanoparticles contribute to antituberculosis therapy?

scientific article published on 27 January 2017

Identification of Piperazinylbenzenesulfonamides as New Inhibitors of Claudin-1 Trafficking and Hepatitis C Virus Entry.

scientific article published on 28 February 2018

Identification of aminopyrimidine-sulfonamides as potent modulators of Wag31-mediated cell elongation in mycobacteria

scientific article published on 28 September 2016

Immunogenic membrane-associated proteins of Mycobacterium tuberculosis revealed by proteomics

scientific article

Impact of Mycobacterium ulcerans biofilm on transmissibility to ecological niches and Buruli ulcer pathogenesis

scientific article

Impact of pe_pgrs33 Gene Polymorphisms on Mycobacterium tuberculosis Infection and Pathogenesis

scientific article

Inactivation of Rv2525c, a substrate of the twin arginine translocation (Tat) system of Mycobacterium tuberculosis, increases beta-lactam susceptibility and virulence

scientific journal article

Increased protective efficacy of recombinant BCG strains expressing virulence-neutral proteins of the ESX-1 secretion system

scientific article

Inhibition of HIV-1 integration by mono- & bi-functionalized triple helix forming oligonucleotides

scientific article published in June 1999

Intrinsic Antibacterial Activity of Nanoparticles Made of β-Cyclodextrins Potentiates Their Effect as Drug Nanocarriers against Tuberculosis

scientific article published on 08 March 2019

Khaya grandifoliola C.DC: a potential source of active ingredients against hepatitis C virus in vitro

scientific article published on 3 February 2016

La mycolactone

scientific article published on 01 February 2016

Legionella pneumophila Modulates Mitochondrial Dynamics to Trigger Metabolic Repurposing of Infected Macrophages

scientific article

Ligand efficiency driven design of new inhibitors of Mycobacterium tuberculosis transcriptional repressor EthR using fragment growing, merging, and linking approaches

scientific article

Long-circulating DNA lipid nanocapsules as new vector for passive tumor targeting

scientific article published on 2 October 2009

Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti

scientific article published in November 2002

LppM impact on the colonization of macrophages by Mycobacterium tuberculosis

scientific article published on 24 May 2016

Macro-array and bioinformatic analyses reveal mycobacterial 'core' genes, variation in the ESAT-6 gene family and new phylogenetic markers for the Mycobacterium tuberculosis complex

scientific article published in February 2004

Mitochondrial Dynamics and Activity in Legionella-Infected Cells

scientific article published on 01 January 2019

Multiplexed Quantitation of Intraphagocyte Mycobacterium tuberculosis Secreted Protein Effectors.

scientific article

Mycobacterial toxin induces analgesia in buruli ulcer by targeting the angiotensin pathways.

scientific article published in June 2014

Mycobacterium tuberculosis Controls Phagosomal Acidification by Targeting CISH-Mediated Signaling

scientific article published on September 2017

Mycobacterium tuberculosis LppM Displays an Original Structure and Domain Composition Linked to a Dual Localization

scientific article

Mycobacterium tuberculosis inhibits human innate immune responses via the production of TLR2 antagonist glycolipids

scientific article published on 2 October 2017

Mycolactone as Analgesic: Subcutaneous Bioavailability Parameters

scientific article published on 12 April 2019

Oxadiazolone derivatives, new promising multi-target inhibitors against M. tuberculosis

scientific article published on 29 August 2018

Phenotypic assays for Mycobacterium tuberculosis infection

scientific article published on 19 May 2017

Polyphenols Inhibit Hepatitis C Virus Entry by a New Mechanism of Action

scientific article published on 22 July 2015

Potent antiviral activity of Solanum rantonnetii and the isolated compounds against hepatitis C virus in vitro

Protection against Mycobacterium ulcerans lesion development by exposure to aquatic insect saliva

scientific article

Proteomic identification of M. tuberculosis protein kinase substrates: PknB recruits GarA, a FHA domain-containing protein, through activation loop-mediated interactions

scientific journal article

Proteomics of Mycobacterium Infection: Moving towards a Better Understanding of Pathogen-Driven Immunomodulation

scientific article published on 30 January 2018

Publisher Correction: Combination therapy for tuberculosis treatment: pulmonary administration of ethionamide and booster co-loaded nanoparticles.

scientific article

Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis

scientific article published on 14 April 2003

Reversion of antibiotic resistance in Mycobacterium tuberculosis by spiroisoxazoline SMARt-420.

scientific article

STAT3 Represses Nitric Oxide Synthesis in Human Macrophages upon Mycobacterium tuberculosis Infection

scientific article published on 7 July 2016

SUPPORT VECTOR MACHINES FOR AUTOMATIC DETECTION OF TUBERCULOSIS BACTERIA IN CONFOCAL MICROSCOPY IMAGES

Spatiotemporal changes of the phagosomal proteome in dendritic cells in response to LPS stimulation

scientific article published on 26 February 2019

Synergy between Circular Bacteriocin AS-48 and Ethambutol against Mycobacterium tuberculosis

scholarly article by Clara Aguilar-Pérez et al published September 2018 in Antimicrobial Agents and Chemotherapy

Synthesis and antimycobacterial evaluation of benzofurobenzopyran analogues

scientific article published on 12 December 2006

Systematic genetic nomenclature for type VII secretion systems.

scientific article

Testing chemical and genetic Modulators in Mycobacterium tuberculosis infected cells using phenotypic assays

scientific article published on January 2015

The EU approved antimalarial pyronaridine shows antitubercular activity and synergy with rifampicin, targeting RNA polymerase

The balance of apoptotic and necrotic cell death in Mycobacterium tuberculosis infected macrophages is not dependent on bacterial virulence

scientific article

Tuberculosis: from genome to vaccine

scientific article

[Aquatic insects and transmission of Mycobacterium ulcerans].

scientific article published in June 2007

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