List of works - Andrew J. Wiemer

A live imaging cell motility screen identifies prostaglandin E2 as a T cell stop signal antagonist

scientific article (publication date: October 2011)

A power law function describes the time- and dose-dependency of Vγ9Vδ2 T cell activation by phosphoantigens

scientific article published on 02 November 2018

Calpain inhibition impairs TNF-alpha-mediated neutrophil adhesion, arrest and oxidative burst

scientific article

Cyclopropene cycloadditions with annulated furans: total synthesis of (+)- and (-)-frondosin B and (+)-frondosin A.

scientific article published on 10 March 2014

Digeranyl bisphosphonate inhibits geranylgeranyl pyrophosphate synthase.

scientific article published on 21 December 2006

Geranylgeranyl diphosphate synthase inhibition induces apoptosis that is dependent upon GGPP depletion, ERK phosphorylation and caspase activation.

scientific article published on 16 March 2017

HMBPP Analog Prodrugs Bypass Energy-Dependent Uptake To Promote Efficient BTN3A1-Mediated Malignant Cell Lysis by Vγ9Vδ2 T Lymphocyte Effectors

scientific article published on 06 June 2016

Inhibition of geranylgeranyl diphosphate synthase induces apoptosis through multiple mechanisms and displays synergy with inhibition of other isoprenoid biosynthetic enzymes.

scientific article

Molecular mechanisms linking geranylgeranyl diphosphate synthase to cell survival and proliferation

scientific article published on 18 August 2016

Novel α-substituted tropolones promote potent and selective caspase-dependent leukemia cell apoptosis.

scientific article published on 20 September 2016

Phosphinophosphonates and Their Tris-pivaloyloxymethyl Prodrugs Reveal a Negatively Cooperative Butyrophilin Activation Mechanism.

scientific article published on 20 February 2017

Phosphonamidate Prodrugs of a Butyrophilin Ligand Display Plasma Stability and Potent Vγ9 Vδ2 T Cell Stimulation

scientific article published on 26 September 2018

Probing the Ligand-Binding Pocket of BTN3A1

scientific article published on 03 July 2019

Quantitative determination of farnesyl and geranylgeranyl diphosphate levels in mammalian tissue

scientific article published on 15 April 2008

Regulation of the Notch-ATM-abl axis by geranylgeranyl diphosphate synthase inhibition

scientific article published on 30 September 2019

Stability and Efficiency of Mixed Aryl Phosphonate Prodrugs

scientific article published on 24 July 2019

Structure-Activity Relationships of Butyrophilin 3 Ligands

scientific article published on 27 April 2020

Synthesis and biological evaluation of santacruzamate A analogues for anti-proliferative and immunomodulatory activity.

scientific article published on 24 August 2016

The focal adhesion kinase inhibitor PF-562,271 impairs primary CD4+ T cell activation.

scientific article published on 05 August 2013

Toward Broad Spectrum Dihydrofolate Reductase Inhibitors Targeting Trimethoprim Resistant Enzymes Identified in Clinical Isolates of Methicillin Resistant Staphylococcus aureus

scientific article published on 15 October 2019

List of works by Andrew J. Wiemer