List of works - Stephen P. Marsden

A biosynthesis-inspired approach to over twenty diverse natural product-like scaffolds. ⬇️

scientific article published on 18 July 2016

A concise, convergent total synthesis of monocerin.

scientific article published in November 2006

A convergent rhodium-catalysed asymmetric synthesis of tetrahydroquinolines. ⬇️

scientific article published in September 2014

A convergent, umpoled synthesis of 2-(1-amidoalkyl)pyridines ⬇️

scientific article published on 4 January 2016

A divergent synthetic approach to diverse molecular scaffolds: assessment of lead-likeness using LLAMA, an open-access computational tool ⬇️

scientific article

A novel, stereoselective and convergent synthesis of aryltetralins.

scientific article published in September 2004

A systematic approach to diverse, lead-like scaffolds from α,α-disubstituted amino acids ⬇️

scientific article published in June 2015

A unified lead-oriented synthesis of over fifty molecular scaffolds ⬇️

scientific article

Alkene hydroboration: hot intermediates that react while they are cooling.

scientific article published in October 2010

Aminomethylhydroxylation of alkenes: Exploitation in the synthesis of scaffolds for small molecule libraries.

scientific article published on 11 February 2015

Asymmetric Aza-Wittig Reactions: Enantioselective Synthesis of β-Quaternary Azacycles

scientific article published on 01 July 2006

Catalyst control in sequential asymmetric allylic substitution: stereodivergent access to N,N-diprotected unnatural amino acids.

scientific article published on 8 June 2011

Catalytic aza-Wittig cyclizations for heteroaromatic synthesis.

scientific article published on 20 May 2008

Chiral N-heterocyclic carbene ligands for asymmetric catalytic oxindole synthesis

scientific article published in August 2008

Chiral vinyl dioxazaborocines in synthesis: asymmetric cuprate additions to β-boronyl acrylates and vinyl sulfones

article

Concise access to indolizidine and pyrroloazepine skeleta via intramolecular Schmidt reactions of azido 1,3-diketones

scientific article published on 03 August 2006

Convenient synthesis of 3-alkoxy-3-aryloxindoles by intramolecular arylation of mandelic amides

scientific article published on 11 July 2008

Convergent, regiospecific synthesis of quinolines from o-aminophenylboronates.

scientific article published on 23 August 2008

Copper catalysed Ullmann type chemistry: from mechanistic aspects to modern development

scientific article published on 03 March 2014

Deconjugation of dehydroamino acids: stereoselective synthesis of racemic (E)-vinylglycines.

scientific article published in November 2005

Design, synthesis and decoration of molecular scaffolds for exploitation in the production of alkaloid-like libraries.

scientific article published on 29 December 2014

Direct Synthesis of N-Alkyl Arylglycines by Organocatalytic Asymmetric Transfer Hydrogenation of N-Alkyl Aryl Imino Esters. ⬇️

scientific article published on 5 October 2017

Efficient asymmetric synthesis of quaternary (E)-vinylglycines by deconjugative alkylation of dehydroamino acids.

scientific article published in November 2006

Efficient unified synthesis of diverse bridged polycyclic scaffolds using a complexity-generating 'stitching' annulation approach

scientific article published on 21 December 2020

Electrophile-directed diastereoselective alkylation of prochiral enediolates.

scientific article published on 3 October 2007

Enhanced asymmetric induction in cycloadditions to bridgehead-chiral vinyl dioxazaborocines

article by Christopher D Davies et al published May 2000 in Tetrahedron Letters

Epoxidation of alkenes by ozone catalysed by Fe(TMP)Cl

article

Evaluating New Chemistry to Drive Molecular Discovery: Fit for Purpose? ⬇️

scientific article

Exploitation of the Ugi–Joullié Reaction in the Synthesis of Libraries of Drug-Like Bicyclic Hydantoins ⬇️

Facile and general synthesis of quaternary 3-aminooxindoles.

scientific article published on 6 June 2008

Fragment-oriented synthesis: β-elaboration of cyclic amine fragments using enecarbamates as platform intermediates

scientific article published on 06 July 2020

Iridium-catalysed amine alkylation with alcohols in water

article

Isotopic labeling for determination of enantiomeric purity by 2H NMR spectroscopy.

scientific article published on 15 November 2007

Picolinamides as effective ligands for copper-catalysed aryl ether formation: structure-activity relationships, substrate scope and mechanistic investigations

scientific article published on 24 October 2014

Radical-mediated direct C–H amination of arenes with secondary amines ⬇️

scientific article published on 11 July 2018

Reagent-Controlled Asymmetric Homologation of Boronic Esters by Enantioenriched Main-Group Chiral Carbenoids

scientific article published on 01 February 2006

Reagent-controlled stereoselective synthesis of lignan-related tetrahydrofurans

scientific article published in October 2004

Recent advances and applications of iridium-catalysed asymmetric allylic substitution

scientific article published on 12 March 2012

Regioselective side-chain amination of 2-alkyl azacycles by radical translocation: total synthesis of tetraponerine T8

scientific article published on 04 January 2021

Rhodium catalysed reactions of silylated diazoacetates: Stereoselective synthesis of α-silylated γ-lactones via CH insertion

scholarly article by Stephen P. Marsden & Wai-Kit Pang published August 1998 in Tetrahedron Letters

Rhodium(III)-catalyzed C-H activation/annulation with vinyl esters as an acetylene equivalent. ⬇️

scientific article published on 28 August 2014

Selective amine cross-coupling using iridium-catalyzed "borrowing hydrogen" methodology

scientific article published in January 2009

Significance of nonstatistical dynamics in organic reaction mechanisms: time-dependent stereoselectivity in cyclopentyne-alkene cycloadditions.

scientific article published in October 2009

Stereocontrolled assembly of tetrasubstituted tetrahydrofurans: a concise synthesis of virgatusin.

scientific article published in August 2005

Synthesis and Application ofP-Stereogenic Phosphines as Superior Reagents in the Asymmetric Aza-Wittig Reaction

scientific article published on 22 August 2007

Synthesis and bio-assay of RCM-derived Bowman-Birk inhibitor analogues

scientific article published on 24 December 2003

Synthesis of benzazoles by hydrogen-transfer catalysis.

scientific article published in May 2009

Synthesis of highly substituted allenylsilanes by alkylidenation of silylketenes ⬇️

scientific article

Synthetic Studies on Psychotrimine: Palladium-Catalysed Arylation of 2-(N-Indolyl) Amides ⬇️

The Wittig reaction cleans up

article

Total synthesis of rapamycin

scientific article published in January 2009

Total synthesis of the immunosuppressants myriocin and 2-epi-myriocin.

scientific article published on 23 August 2008

Total synthesis of the indolizidine alkaloid tashiromine

scientific article

Towards the realisation of lead-oriented synthesis

scientific article

Translation of innovative chemistry into screening libraries: an exemplar partnership from the European Lead Factory ⬇️

scientific article published on 09 May 2018

List of works by Stephen P. Marsden

A biosynthesis-inspired approach to over twenty diverse natural product-like scaffolds. ⬇️

A concise, convergent total synthesis of monocerin.

A convergent rhodium-catalysed asymmetric synthesis of tetrahydroquinolines. ⬇️

A convergent, umpoled synthesis of 2-(1-amidoalkyl)pyridines ⬇️

A divergent synthetic approach to diverse molecular scaffolds: assessment of lead-likeness using LLAMA, an open-access computational tool ⬇️

A novel, stereoselective and convergent synthesis of aryltetralins.

A systematic approach to diverse, lead-like scaffolds from α,α-disubstituted amino acids ⬇️

A unified lead-oriented synthesis of over fifty molecular scaffolds ⬇️

Alkene hydroboration: hot intermediates that react while they are cooling.

Aminomethylhydroxylation of alkenes: Exploitation in the synthesis of scaffolds for small molecule libraries.

Asymmetric Aza-Wittig Reactions: Enantioselective Synthesis of β-Quaternary Azacycles

Catalyst control in sequential asymmetric allylic substitution: stereodivergent access to N,N-diprotected unnatural amino acids.

Catalytic aza-Wittig cyclizations for heteroaromatic synthesis.

Chiral N-heterocyclic carbene ligands for asymmetric catalytic oxindole synthesis

Chiral vinyl dioxazaborocines in synthesis: asymmetric cuprate additions to β-boronyl acrylates and vinyl sulfones

Concise access to indolizidine and pyrroloazepine skeleta via intramolecular Schmidt reactions of azido 1,3-diketones

Convenient synthesis of 3-alkoxy-3-aryloxindoles by intramolecular arylation of mandelic amides

Convergent, regiospecific synthesis of quinolines from o-aminophenylboronates.

Copper catalysed Ullmann type chemistry: from mechanistic aspects to modern development

Deconjugation of dehydroamino acids: stereoselective synthesis of racemic (E)-vinylglycines.

Design, synthesis and decoration of molecular scaffolds for exploitation in the production of alkaloid-like libraries.

Direct Synthesis of N-Alkyl Arylglycines by Organocatalytic Asymmetric Transfer Hydrogenation of N-Alkyl Aryl Imino Esters. ⬇️

Efficient asymmetric synthesis of quaternary (E)-vinylglycines by deconjugative alkylation of dehydroamino acids.

Efficient unified synthesis of diverse bridged polycyclic scaffolds using a complexity-generating 'stitching' annulation approach

Electrophile-directed diastereoselective alkylation of prochiral enediolates.

Enhanced asymmetric induction in cycloadditions to bridgehead-chiral vinyl dioxazaborocines

Epoxidation of alkenes by ozone catalysed by Fe(TMP)Cl

Evaluating New Chemistry to Drive Molecular Discovery: Fit for Purpose? ⬇️

Exploitation of the Ugi–Joullié Reaction in the Synthesis of Libraries of Drug-Like Bicyclic Hydantoins ⬇️

Facile and general synthesis of quaternary 3-aminooxindoles.

Fragment-oriented synthesis: β-elaboration of cyclic amine fragments using enecarbamates as platform intermediates

Iridium-catalysed amine alkylation with alcohols in water

Isotopic labeling for determination of enantiomeric purity by 2H NMR spectroscopy.

Picolinamides as effective ligands for copper-catalysed aryl ether formation: structure-activity relationships, substrate scope and mechanistic investigations

Radical-mediated direct C–H amination of arenes with secondary amines ⬇️

Reagent-Controlled Asymmetric Homologation of Boronic Esters by Enantioenriched Main-Group Chiral Carbenoids

Reagent-controlled stereoselective synthesis of lignan-related tetrahydrofurans

Recent advances and applications of iridium-catalysed asymmetric allylic substitution

Regioselective side-chain amination of 2-alkyl azacycles by radical translocation: total synthesis of tetraponerine T8

Rhodium catalysed reactions of silylated diazoacetates: Stereoselective synthesis of α-silylated γ-lactones via CH insertion

Rhodium(III)-catalyzed C-H activation/annulation with vinyl esters as an acetylene equivalent. ⬇️

Selective amine cross-coupling using iridium-catalyzed "borrowing hydrogen" methodology

Significance of nonstatistical dynamics in organic reaction mechanisms: time-dependent stereoselectivity in cyclopentyne-alkene cycloadditions.

Stereocontrolled assembly of tetrasubstituted tetrahydrofurans: a concise synthesis of virgatusin.

Synthesis and Application ofP-Stereogenic Phosphines as Superior Reagents in the Asymmetric Aza-Wittig Reaction

Synthesis and bio-assay of RCM-derived Bowman-Birk inhibitor analogues

Synthesis of benzazoles by hydrogen-transfer catalysis.

Synthesis of highly substituted allenylsilanes by alkylidenation of silylketenes ⬇️

Synthetic Studies on Psychotrimine: Palladium-Catalysed Arylation of 2-(N-Indolyl) Amides ⬇️

The Wittig reaction cleans up

Total synthesis of rapamycin

Total synthesis of the immunosuppressants myriocin and 2-epi-myriocin.

Total synthesis of the indolizidine alkaloid tashiromine

Towards the realisation of lead-oriented synthesis

Translation of innovative chemistry into screening libraries: an exemplar partnership from the European Lead Factory ⬇️