List of works by Alessandro Ori

A systems biology approach for the investigation of the heparin/heparan sulfate interactome

scientific article

ATR regulates neuronal activity by modulating presynaptic firing

scientific article published in 2021

An integrated approach for genome annotation of the eukaryotic thermophile Chaetomium thermophilum

scientific article published on 14 November 2014

Association of condensin with chromosomes depends on DNA binding by its HEAT-repeat subunits

scientific article

Author Correction: TRPS1 shapes YAP/TEAD-dependent transcription in breast cancer cells

scientific article published in Nature Communications

Automated structure modeling of large protein assemblies using crosslinks as distance restraints

scientific article

Cations modulate polysaccharide structure to determine FGF-FGFR signaling: a comparison of signaling and inhibitory polysaccharide interactions with FGF-1 in solution

scientific article published in June 2009

Cell type-specific nuclear pores: a case in point for context-dependent stoichiometry of molecular machines

scientific article

Cellular and epigenetic drivers of stem cell ageing

scientific article published on 01 September 2018

Cellular apoptosis susceptibility (CAS) is linked to integrin β1 and required for tumor cell migration and invasion in hepatocellular carcinoma (HCC).

scientific article published on 23 March 2016

Characterisation of the interaction of neuropilin-1 with heparin and a heparan sulfate mimetic library of heparin-derived sugars

scientific article

Characterization and quantification of proteins secreted by single human embryos prior to implantation

scientific article

Cohesin-mediated NF-κB signaling limits hematopoietic stem cell self-renewal in aging and inflammation

scientific article published on 07 December 2018

Comparable stabilisation, structural changes and activities can be induced in FGF by a variety of HS and non-GAG analogues: implications for sequence-activity relationships

scientific article published on 3 September 2010

Comparison of Protein Quantification in a Complex Background by DIA and TMT Workflows with Fixed Instrument Time

scientific article published on 20 February 2019

Differential scanning fluorimetry measurement of protein stability changes upon binding to glycosaminoglycans: a screening test for binding specificity

scientific article published on May 2010

Disentangling Genetic and Environmental Effects on the Proteotypes of Individuals

scientific article published on 25 April 2019

Diversification of the structural determinants of fibroblast growth factor-heparin interactions: implications for binding specificity

scientific article

Following Protein–Glycosaminoglycan Polysaccharide Interactions with Differential Scanning Fluorimetry

scientific article published on 01 January 2012

Histone Deacetylase Inhibitors (HDACi) Cause the Selective Depletion of Bromodomain Containing Proteins (BCPs).

scientific article published on 9 March 2015

Identification of heparin-binding sites in proteins by selective labeling

scientific article

In situ structural analysis of the human nuclear pore complex

scientific article

Integrated Transcriptome and Proteome Analyses Reveal Organ-Specific Proteome Deterioration in Old Rats

scientific article published on 17 September 2015

Integrated structural analysis of the human nuclear pore complex scaffold

scientific journal article

Landscape of nuclear transport receptor cargo specificity

scientific article published on 18 December 2017

Loss of metabolic plasticity underlies metformin toxicity in aged Caenorhabditis elegans

scientific article published on 02 November 2020

Mapping protein carboxymethylation sites provides insights into their role in proteostasis and cell proliferation

scientific article published on 18 November 2021

Metabolic determination of cell fate through selective inheritance of mitochondria

scientific article published on 14 February 2022

NUFIP1 is a ribosome receptor for starvation-induced ribophagy

scientific article published on 26 April 2018

Nucleoporin Nup155 is part of the p53 network in liver cancer

scientific article published on 14 May 2019

Profiling of gallbladder carcinoma reveals distinct miRNA profiles and activation of STAT1 by the tumor suppressive miRNA-145-5p

scientific article published on 18 March 2019

Proliferation and migration activities of fibroblast growth factor-2 in endothelial cells are modulated by its direct interaction with heparin affin regulatory peptide

scientific article published on 12 October 2014

Prosurvival function of the cellular apoptosis susceptibility/importin-α1 transport cycle is repressed by p53 in liver cancer.

scientific article published on 17 July 2014

Protein lifetimes in aged brains reveal a proteostatic adaptation linking physiological aging to neurodegeneration

scientific article published on 20 May 2022

Quantifying compartment‐associated variations of protein abundance in proteomics data

scholarly article by Luca Parca et al published July 2018 in Molecular Systems Biology

Rapid proteotyping reveals cancer biology and drug response determinants in the NCI-60 cells

Reduced proteasome activity in the aging brain results in ribosome stoichiometry loss and aggregation

scientific article published on 01 June 2020

Spatial Tissue Proteomics Quantifies Inter- and Intratumor Heterogeneity in Hepatocellular Carcinoma (HCC).

scientific article published on 23 January 2018

Spatially resolved analysis of FFPE tissue proteomes by quantitative mass spectrometry

scientific article published on 31 July 2020

Spatiotemporal variation of mammalian protein complex stoichiometries.

scientific article published on 14 March 2016

Species comparison of liver proteomes reveals links to naked mole-rat longevity and human aging

Structural basis for assembly and function of the Nup82 complex in the nuclear pore scaffold

scientific article

Symportin 1 chaperones 5S RNP assembly during ribosome biogenesis by occupying an essential rRNA-binding site

scientific article published on 7 April 2015

TRPS1 shapes YAP/TEAD-dependent transcription in breast cancer cells

scientific article published in Nature Communications

The GID ubiquitin ligase complex is a regulator of AMPK activity and organismal lifespan

scientific article published on 03 December 2019

The endosomal transcriptional regulator RNF11 integrates degradation and transport of EGFR.

scientific article

The heparanome and regulation of cell function: structures, functions and challenges

scientific article

The natural compound atraric acid suppresses androgen-regulated neo-angiogenesis of castration-resistant prostate cancer through angiopoietin 2

scientific article published on 05 May 2022

The quantitative proteome of a human cell line.

scientific article

The use of targeted proteomics to determine the stoichiometry of large macromolecular assemblies

scientific article

Vulnerability of progeroid smooth muscle cells to biomechanical forces is mediated by MMP13

scientific article published on 17 August 2020

What have we learned on aging from omics studies?

scientific article published on 16 June 2017

Xlink Analyzer: software for analysis and visualization of cross-linking data in the context of three-dimensional structures

scientific article published on 7 February 2015