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List of works by Christoph Harms

ARC is a novel therapeutic approach against acetaminophen-induced hepatocellular necrosis

scientific article published on 6 October 2012

Cellular heterogeneity contributes to subtype-specific expression of ZEB1 in human glioblastoma

scientific article published on 25 September 2017

Certain types of iron oxide nanoparticles are not suited to passively target inflammatory cells that infiltrate the brain in response to stroke

scientific article published on 27 February 2013

Combined temozolomide and sunitinib treatment leads to better tumour control but increased vascular resistance in O6-methylguanine methyltransferase-methylated gliomas

scientific article published on 14 March 2013

Corrigendum: Protein kinase CK2 links extracellular growth factor signaling with the control of p27Kip1 stability in the heart

scholarly article published in Nature Medicine

Critical role for FoxO3a-dependent regulation of p21CIP1/WAF1 in response to statin signaling in cardiac myocytes

scientific article published on 07 December 2006

Elevated levels of plasma homocysteine, deficiencies in dietary folic acid and uracil-DNA glycosylase impair learning in a mouse model of vascular cognitive impairment

scientific article

Ephrin-B2-EphB4 communication mediates tumor-endothelial cell interactions during hematogenous spread to spinal bone in a melanoma metastasis model

scientific article published on 28 September 2020

Folate deficiency increases mtDNA and D-1 mtDNA deletion in aged brain of mice lacking uracil-DNA glycosylase.

scientific article published on 28 January 2011

Folate deficiency induces neurodegeneration and brain dysfunction in mice lacking uracil DNA glycosylase

scientific article published on July 2008

Glioma Stem Cells but Not Bulk Glioma Cells Upregulate IL-6 Secretion in Microglia/Brain Macrophages via Toll-like Receptor 4 Signaling

scientific article published on 30 March 2016

Histone acetylation and CREB binding protein are required for neuronal resistance against ischemic injury

scientific article

Hyperbaric oxygenation induced tolerance against focal cerebral ischemia in mice is strain dependent.

scientific article published in July 2000

ICAM1 depletion reduces spinal metastasis formation in vivo and improves neurological outcome

scientific article published on 25 February 2015

Identification of 2-[4-[(4-Methoxyphenyl)methoxy]-phenyl]acetonitrile and Derivatives as Potent Oct3/4 Inducers

scientific article published on 7 May 2015

Imaging early endothelial inflammation following stroke by core shell silica superparamagnetic glyconanoparticles that target selectin

In vivo imaging of the inflammatory receptor CD40 after cerebral ischemia using a fluorescent antibody

scientific article

Increased postischemic brain injury in mice deficient in uracil-DNA glycosylase

scientific article

Inhibition of Na+,K+-ATPase activity in cultured rat cerebellar granule cells prevents the onset of apoptosis induced by low potassium

scientific article published on 01 March 2000

Inhibition of histone deacetylation protects wild-type but not gelsolin-deficient neurons from oxygen/glucose deprivation.

scientific article published in August 2006

Inhibition of histone deacetylation protects wildtype but not gelsolin-deficient mice from ischemic brain injury

scientific article published on 23 December 2007

Inhibition of histone methyltransferases SUV39H1 and G9a leads to neuroprotection in an in vitro model of cerebral ischemia

scientific article

Interaction of ARC and Daxx: A Novel Endogenous Target to Preserve Motor Function and Cell Loss after Focal Brain Ischemia in Mice

scientific article

Ischemic injury in experimental stroke depends on angiotensin II.

scientific article published in February 2002

MPTH-08ZEB1 IS UBIQUITOUSLY EXPRESSED ACROSS SUBTYPES IN HUMAN GLIOBLASTOMA AND A SURROGATE MARKER OF TUMOR PURITY.

scientific article published on 9 November 2015

NDRG1 overexpressing gliomas are characterized by reduced tumor vascularization and resistance to antiangiogenic treatment

scientific article published on 19 August 2015

Nestin-expressing cells divide and adopt a complex electrophysiologic phenotype after transient brain ischemia

scientific article published in December 2005

Neuronal gelsolin prevents apoptosis by enhancing actin depolymerization

scientific article published in January 2004

Neuroprotective effects of atorvastatin against glutamate-induced excitotoxicity in primary cortical neurones

scientific article published in March 2005

P17.25GLIOMA-INITIATING CELL INDUCED INTERLEUKIN-6 PRODUCTION IS MEDIATED BY TOLL-LIKE RECEPTOR 4 IN MICROGLIA.

scientific article published in September 2014

Passive Entrapment of Tumor Cells Determines Metastatic Dissemination to Spinal Bone and Other Osseous Tissues

scientific article

Physical activity improves long-term stroke outcome via endothelial nitric oxide synthase-dependent augmentation of neovascularization and cerebral blood flow

scientific article published on 12 October 2006

Prognostic Relevance of Tumor Purity and Interaction with MGMT Methylation in Glioblastoma

scientific article published in February 2017

Protein kinase CK2 links extracellular growth factor signaling with the control of p27Kip1 stability in the heart

article by Ludger Hauck et al published March 2008 in Nature Medicine

Reduced Hippocampal Neurogenesis in Mice Deficient in Apoptosis Repressor with Caspase Recruitment Domain (ARC)

scientific article published on 26 July 2019

Refining humane endpoints in mouse models of disease by systematic review and machine learning-based endpoint definition

scientific article published on 18 April 2019

Role of NAD(P)H:quinone oxidoreductase in the progression of neuronal cell death in vitro and following cerebral ischaemia in vivo

scientific journal article

Role of nitric oxide in the ethylcholine aziridinium model of delayed apoptotic neurodegeneration in vivo and in vitro

article

Roller culture of free-floating retinal slices: a new system of organotypic cultures of adult rat retina

scientific article published on 15 September 2006

SUMO2/3 conjugation is an endogenous neuroprotective mechanism

scientific article published on 24 August 2011

Serotonin uptake and release mechanisms in developing cultures of rat embryonic raphe neurons: age- and region-specific differences.

scientific article published on January 2000

Serum insulin-like growth factor I and ischemic brain injury.

scientific article published on 24 October 2007

Small ubiquitin-like modifier 1-3 conjugation [corrected] is activated in human astrocytic brain tumors and is required for glioblastoma cell survival

scientific article published on 28 November 2012

SorCS2 facilitates release of endostatin from astrocytes and controls post-stroke angiogenesis

scientific article published on 03 January 2020

Stage 1 Registered Report: Effect of deficient phagocytosis on neuronal survival and neurological outcome after temporary middle cerebral artery occlusion (tMCAo).

scientific article

Systemic application of AAV vectors targeting GFAP-expressing astrocytes in Z-Q175-KI Huntington's disease mice.

scientific article

TAT-apoptosis repressor with caspase recruitment domain protein transduction rescues mice from fulminant liver failure.

scientific article published on 3 July 2012

TRPV4 inhibition prevents paclitaxel-induced neurotoxicity in preclinical models.

scientific article published on 28 April 2018

The human longevity gene homolog INDY and interleukin-6 interact in hepatic lipid metabolism

scientific article

Uncoupling the Excitatory Amino Acid Transporter 2 From Its C-Terminal Interactome Restores Synaptic Glutamate Clearance at Corticostriatal Synapses and Alleviates Mutant Huntingtin-Induced Hypokinesia

scientific article published on 01 January 2021

Unique properties of PTEN-L contribute to neuroprotection in response to ischemic-like stress

scientific article published on 28 February 2019

Vascular signal transducer and activator of transcription-3 promotes angiogenesis and neuroplasticity long-term after stroke

scientific article published on 20 March 2015

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