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List of works by Joan Clària

5-lipoxygenase activating protein signals adipose tissue inflammation and lipid dysfunction in experimental obesity.

scientific article published on 5 March 2010

5-lipoxygenase deficiency reduces hepatic inflammation and tumor necrosis factor alpha-induced hepatocyte damage in hyperlipidemia-prone ApoE-null mice.

scientific article published on March 2010

5-lipoxygenase regulates malignant mesothelial cell survival: involvement of vascular endothelial growth factor.

scientific article

A coding polymorphism in the 12-lipoxygenase gene is associated to essential hypertension and urinary 12(S)-HETE.

scientific article

Acute-On-Chronic Liver Failure, Human Serum Albumin and Immune-Modulation: The Beginning of an Exciting Adventure.

scientific article published on 12 December 2017

Albumin in decompensated cirrhosis: new concepts and perspectives

scientific article published on 26 February 2020

Albumin internalizes and inhibits endosomal TLR signaling in leukocytes from patients with decompensated cirrhosis

scientific article published on 01 October 2020

Altered biosynthesis of leukotrienes and lipoxins and host defense disorders in patients with cirrhosis and ascites.

scientific article published in July 1998

An investigation of the resolution of inflammation (catabasis) in COPD.

scientific article published on 13 November 2012

Anti-Inflammatory and Proresolving Effects of the Omega-6 Polyunsaturated Fatty Acid Adrenic Acid

scientific article published on 02 October 2020

Aquaretic effect of the kappa-opioid agonist RU 51599 in cirrhotic rats with ascites and water retention

scientific article

Aspirin in the 21st century-common mechanisms of disease and their modulation by aspirin: a report from the 2015 scientific conference of the international aspirin foundation, 28 August, London, UK.

scientific article

Association of a variant in the gene encoding for ERV1/ChemR23 with reduced inflammation in visceral adipose tissue from morbidly obese individuals

scientific article

Atrial natriuretic peptide antagonizes endothelin-induced calcium increase and cell contraction in cultured human hepatic stellate cells

scientific article published on 01 August 1999

Blood metabolomics uncovers inflammation-associated mitochondrial dysfunction as a potential mechanism underlying ACLF

scientific article published on 25 November 2019

Blunted natriuretic response to human urine extracts with Na+, K+-ATPase inhibiting activity in experimental cirrhosis

scientific article published on 01 May 1994

Brachial and femoral artery blood flow in cirrhosis: relationship to kidney dysfunction.

scientific article

Bradykinin attenuates hepatocellular damage and fibrosis in rats with chronic liver injury

scientific article published on 26 September 2007

Carbon tetrachloride induced cirrhosis in rats: a useful tool for investigating the pathogenesis of ascites in chronic liver disease.

scientific article published in January 1992

Cell-specific PPARγ deficiency establishes anti-inflammatory and anti-fibrogenic properties for this nuclear receptor in non-parenchymal liver cells

scientific article

Changes in liver and plasma acetylcholinesterase in rats with cirrhosis induced by bile duct ligation

scientific article published in March 2006

Cigarette smoke concentrate increases 8-epi-PGF2alpha and TGFbeta1 secretion in rat mesangial cells

scientific article published on June 2004

Circulating CXCL10 in cirrhotic portal hypertension might reflect systemic inflammation and predict ACLF and mortality.

scientific article published on 6 November 2017

Diagnosis of functional kidney failure of cirrhosis with Doppler sonography: Prognostic value of resistive index

scientific article published on 01 October 1994

Differential inflammasome activation predisposes to acute-on-chronic liver failure in human and experimental cirrhosis with and without previous decompensation

scientific article published on 02 April 2020

Disruption of the 12/15-lipoxygenase gene (Alox15) protects hyperlipidemic mice from nonalcoholic fatty liver disease

scientific article published on 21 October 2010

Diversity of lipid mediators in human adipose tissue depots.

scientific article published on 30 January 2013

Effect of upright posture and physical exercise on endogenous neurohormonal systems in cirrhotic patients with sodium retention and normal supine plasma renin, aldosterone, and norepinephrine levels

scientific article published on 01 August 1995

Effects of celecoxib and naproxen on renal function in nonazotemic patients with cirrhosis and ascites.

scientific article

Effects of low-sodium diet and spironolactone on portal pressure in patients with compensated cirrhosis

scientific article published on 01 May 1994

Endogenous cannabinoids: a new system involved in the homeostasis of arterial pressure in experimental cirrhosis in the rat.

scientific article published in January 2002

Endothelin 1 does not play a major role in the homeostasis of arterial pressure in cirrhotic rats with ascites.

scientific article published in June 1995

F2 isoprostane is already increased at the onset of type 1 diabetes mellitus: effect of glycemic control

scientific article published in September 2004

Gene expression profiling of renal dysfunction in rats with experimental cirrhosis.

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Hepatic inflammasome activation as origin of Interleukin-1α and Interleukin-1β in liver cirrhosis

scientific article published on 21 October 2020

Impaired responsiveness to angiotensin II in experimental cirrhosis: role of nitric oxide

scientific article published on 01 August 1993

Increased apoptosis dependent on caspase-3 activity in polymorphonuclear leukocytes from patients with cirrhosis and ascites.

scientific article published in July 2004

Increased nitric oxide—dependent vasorelaxation in aortic rings of cirrhotic rats with ascites

scientific article published on 01 December 1994

Increased susceptibility to exacerbated liver injury in hypercholesterolemic ApoE-deficient mice: potential involvement of oxysterols

scientific article published on 8 January 2009

Inhibition of 5-lipoxygenase-activating protein abrogates experimental liver injury: role of Kupffer cells.

scientific article published on 20 July 2005

Inhibition of soluble epoxide hydrolase modulates inflammation and autophagy in obese adipose tissue and liver: role for omega-3 epoxides

scientific article

Integrative microRNA profiling in alcoholic hepatitis reveals a role for microRNA-182 in liver injury and inflammation.

scientific article published on 10 May 2016

Intracellular calcium concentration in vascular smooth muscle cells of rats with cirrhosis.

scientific article published on October 1994

Leukocytes, Systemic Inflammation and Immunopathology in Acute-on-Chronic Liver Failure

scientific article published on 08 December 2020

Macrophage Activation Markers, CD163 and CD206, in Acute-on-Chronic Liver Failure

scientific article published on 09 May 2020

Molecular genetic reports in clinical practice: content and nomenclature of mutations

scientific article published on 22 October 2009

Molecular interplay between Δ5/Δ6 desaturases and long-chain fatty acids in the pathogenesis of non-alcoholic steatohepatitis.

scientific article

Natriuretic hormone activity in the urine of cirrhotic patients

scientific article published on 01 September 1990

Natural killer cell recognition and killing of activated hepatic stellate cells

scientific article published on 30 March 2012

New insights into the regulation of liver inflammation and oxidative stress

scientific article published on December 2006

New insights into the role of macrophages in adipose tissue inflammation and Fatty liver disease: modulation by endogenous omega-3 Fatty Acid-derived lipid mediators

scientific article published on 5 October 2011

Nitric oxide production in arterial vessels of cirrhotic rats

scientific article published on February 1995

Omega-3-derived mediators counteract obesity-induced adipose tissue inflammation.

scientific article published on 21 May 2013

Orchestration of Tryptophan‐Kynurenine Pathway, Acute Decompensation, and Acute‐on‐Chronic Liver Failure in Cirrhosis

scientific article published on 19 March 2019

Pathogenesis of arterial hypotension in cirrhotic rats with ascites: Role of endogenous nitric oxide

scientific article published on 01 February 1992

Pharmacological intervention of cyclooxygenase-2 and 5-lipoxygenase pathways. Impact on inflammation and cancer.

scientific article

Polymorphisms in the IL-1 gene cluster influence systemic inflammation in patients at risk for acute-on-chronic liver failure.

scientific article

Pro-resolving actions of SPM in adipose tissue biology.

scientific article published on 21 March 2017

Pro-resolving mediators produced from EPA and DHA: Overview of the pathways involved and their mechanisms in metabolic syndrome and related liver diseases

scientific article

Prostaglandin E2 Exerts Multiple Regulatory Actions on Human Obese Adipose Tissue Remodeling, Inflammation, Adaptive Thermogenesis and Lipolysis

scientific article

Prostaglandins and other cyclooxygenase-dependent arachidonic acid metabolites and the kidney in liver disease.

scientific article published on October 2003

Protection from hepatic lipid accumulation and inflammation by genetic ablation of 5-lipoxygenase.

scientific article published on 21 March 2010

Publication of a special issue: resolution of acute inflammation and the role of lipid mediators.

scientific article

Publication of the Special Issue “Fourth European Workshop on Lipid Mediators”

scientific article published on 01 October 2013

Regulatory effects of arachidonate 5-lipoxygenase on hepatic microsomal TG transfer protein activity and VLDL-triglyceride and apoB secretion in obese mice.

scientific article

Renal effects of acute isosorbide-5-mononitrate administration in cirrhosis.

scientific article

Renal effects of natriuretic peptide receptor blockade in cirrhotic rats with ascites.

scientific article

Renal sodium handling in preascitic cirrhosis

scientific article published in May 2001

Resolution of adipose tissue inflammation.

scientific article

Resolution of inflammation in obesity-induced liver disease.

scientific article published on 20 August 2012

Resolvin D1 and Its Precursor Docosahexaenoic Acid Promote Resolution of Adipose Tissue Inflammation by Eliciting Macrophage Polarization toward an M2-Like Phenotype

scientific article published on 17 October 2011

Resolvin D1 and resolvin D2 govern local inflammatory tone in obese fat

scientific article

Resolvin D1 primes the resolution process initiated by calorie restriction in obesity-induced steatohepatitis.

scientific article published on 18 November 2013

Resolvins, specialized proresolving lipid mediators, and their potential roles in metabolic diseases

scientific article

Role for PPARγ in obesity-induced hepatic steatosis as determined by hepatocyte- and macrophage-specific conditional knockouts

scientific article published on 19 April 2011

Role of bioactive lipid mediators in obese adipose tissue inflammation and endocrine dysfunction.

scientific article published on 30 September 2015

Role of nitric oxide and prostacyclin in the control of renal perfusion in experimental cirrhosis

scientific article published on 01 September 1995

Selective inhibition of cyclooxygenase 2 spares renal function and prostaglandin synthesis in cirrhotic rats with ascites

scientific article published on 01 May 1999

Signaling and Immunoresolving Actions of Resolvin D1 in Inflamed Human Visceral Adipose Tissue

scientific article

Smoking increases serum levels of transforming growth factor-beta in diabetic patients

scientific article published on 01 November 1999

Stimulation of soluble guanylate cyclase exerts antiinflammatory actions in the liver through a VASP/NF-κB/NLRP3 inflammasome circuit

scientific article published on 26 October 2020

Systemic inflammation in decompensated cirrhosis: Characterization and role in acute-on-chronic liver failure

scientific article published on 2 August 2016

The Acute-on-Chronic Liver Failure Syndrome, or When the Innate Immune System Goes Astray

scientific article published on November 2016

The effects of smoking and its cessation on 8-epi-PGF2alpha and transforming growth factor-beta 1 in Type 1 diabetes mellitus.

scientific article published in March 2004

The pathogen receptor liver and lymph node sinusoidal endotelial cell C-type lectin is expressed in human Kupffer cells and regulated by PU.1.

scientific article

The results in rodent models of atherosclerosis are not interchangeable

scientific article published on 24 July 2007

The selective cyclooxygenase-2 inhibitor SC-236 reduces liver fibrosis by mechanisms involving non-parenchymal cell apoptosis and PPARgamma activation.

scientific article published on 4 May 2005

The selective cyclooxygenase-2 inhibitor celecoxib modulates the formation of vasoconstrictor eicosanoids and activates PPARgamma. Influence of albumin

scientific article published in January 2005

The soluble guanylate cyclase stimulator IW-1973 prevents inflammation and fibrosis in experimental non-alcoholic steatohepatitis

scientific article published on 27 December 2017

Urinary excretion of urodilatin in patients with cirrhosis

scientific article published in December 1996

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