List of works by Roberto Mallone

21-Hydroxylase epitopes are targeted by CD8 T cells in autoimmune Addison’s disease

scientific article published on 03 August 2010

A rapid lateral flow immunoassay for the detection of tyrosine phosphatase-like protein IA-2 autoantibodies in human serum

scientific article

A simple and fast non-radioactive bridging immunoassay for insulin autoantibodies

scientific article

Anti-CD38 autoantibodies in type? diabetes

scientific article

Anti-CD38 autoantibodies: characterisation in new-onset type I diabetes and latent autoimmune diabetes of the adult (LADA) and comparison with other islet autoantibodies.

scientific article published on 24 October 2002

Antibodies recognizing Mycobacterium avium paratuberculosis epitopes cross-react with the beta-cell antigen ZnT8 in Sardinian type 1 diabetic patients

scientific article

Antigen-based immune therapeutics for type 1 diabetes: magic bullets or ordinary blanks?

scientific article published on 14 May 2011

Arsenic trioxide and breast cancer: analysis of the apoptotic, differentiative and immunomodulatory effects

scientific article published in May 2002

Autoantibodies to fibroblasts induce a proadhesive and proinflammatory fibroblast phenotype in patients with systemic sclerosis

scientific article published on 01 June 2002

Autoantibody response to CD38 in Caucasian patients with type 1 and type 2 diabetes: immunological and genetic characterization.

scientific article published in April 2001

Beyond the hormone: insulin as an autoimmune target in type 1 diabetes

scientific article published on 23 June 2011

Biomarkers for immune intervention trials in type 1 diabetes

scientific article published on 27 February 2013

CD38 expressed on human monocytes: a coaccessory molecule in the superantigen-induced proliferation

scholarly article

CD38 stimulation lowers the activation threshold and enhances the alloreactivity of cord blood T cells by activating the phosphatidylinositol 3-kinase pathway and inducing CD73 expression

scientific article published on 01 May 1999

CD8+ T-cell responses identify beta-cell autoimmunity in human type 1 diabetes

scientific article published on 01 March 2007

Characterization of a CD38-like 78-kilodalton soluble protein released from B cell lines derived from patients with X-linked agammaglobulinemia

scientific article published on June 1998

Characterization of immune response to novel HLA-A2-restricted epitopes from zinc transporter 8 in type 1 diabetes

scientific article published on 2 November 2015

Combinatorial detection of autoreactive CD8+ T cells with HLA-A2 multimers: a multi-centre study by the Immunology of Diabetes Society T Cell Workshop

scientific article published in December 2017

Comparison of cryopreservation methods on T-cell responses to islet and control antigens from type 1 diabetic patients and controls

scientific article published on 01 November 2011

Correction: MHC Class II Tetramers Made from Isolated Recombinant α and β Chains Refolded with Affinity-Tagged Peptides.

scientific article published on 24 September 2013

Correction: MHC Class II Tetramers Made from Isolated Recombinant α and β Chains Refolded with Affinity-Tagged Peptides.

scientific article

Critical parameters in blood processing for T-cell assays: validation on ELISpot and tetramer platforms

Current approaches to measuring human islet-antigen specific T cell function in type 1 diabetes ⬇️

scientific article published on September 15, 2010

Differential recognition and activation thresholds in human autoreactive GAD-specific T-cells

scientific article

Equivalent specificity of peripheral blood and islet-infiltrating CD8+ T lymphocytes in spontaneously diabetic HLA-A2 transgenic NOD mice.

scientific article published in April 2008

Evidence that nasal insulin induces immune tolerance to insulin in adults with autoimmune diabetes ⬇️

scientific article

Expression of NKG2D and CD107 in CD8(+) effector memory lymphocytes in Churg-Strauss syndrome

scientific article published in January 2012

Functional avidity directs T-cell fate in autoreactive CD4+ T cells

scientific article published on 19 July 2005

GAD65-specific CD4+ T-cells with high antigen avidity are prevalent in peripheral blood of patients with type 1 diabetes

scientific article

HLA class I epitope discovery in type 1 diabetes

scientific article published on October 2006

HLA-B7-restricted islet epitopes are differentially recognized in type 1 diabetic children and adults and form weak peptide-HLA complexes

scientific article

Human CD38 (ADP-ribosyl cyclase) is a counter-receptor of CD31, an Ig superfamily member

scientific article

Human CD38 and its ligand CD31 define a unique lamina propria T lymphocyte signaling pathway

scientific article published on 19 January 2001

Human accessory cells activate fresh, normal, tumor-distant T lymphocytes but not tumor-infiltrating T lymphocytes to lyse autologous tumor cells in a primary cytotoxic T lymphocyte assay in renal cell carcinoma

scientific article published on 01 October 2001

Immune biomarkers in immunotherapeutic trials for type 1 diabetes: cui prodest?

scientific article published on 31 July 2012

Immunization of HLA class I transgenic mice identifies autoantigenic epitopes eliciting dominant responses in type 1 diabetes patients

scientific article

Immunodominance of HLA-B27-restricted HIV KK10-specific CD8(+) T-cells is not related to naïve precursor frequency

scientific article published on 13 October 2012

Immunology of Diabetes Society T-Cell Workshop: HLA class I tetramer-directed epitope validation initiative T-Cell Workshop Report-HLA Class I Tetramer Validation Initiative

scientific article published on 01 November 2011

Immunology of Diabetes Society T-Cell Workshop: HLA class II tetramer-directed epitope validation initiative.

scientific article published on November 2011

Infectious triggers in type 1 diabetes: is there a case for epitope mimicry?

scientific article published on September 2013

Inflammation-Induced Citrullinated Glucose-Regulated Protein 78 Elicits Immune Responses in Human Type 1 Diabetes

article

Insulin and type 1 diabetes: immune connections

scientific article published on 17 January 2013

Islet-reactive CD8+ T cell frequencies in the pancreas, but not in blood, distinguish type 1 diabetic patients from healthy donors

scientific article published in February 2018

Isolation and preservation of peripheral blood mononuclear cells for analysis of islet antigen-reactive T cell responses: position statement of the T-Cell Workshop Committee of the Immunology of Diabetes Society ⬇️

scientific article published on 05 October 2010

Long-lasting immune responses 4 years after GAD-alum treatment in children with type 1 diabetes

scientific article

Long-term exposure to Myozyme results in a decrease of anti-drug antibodies in late-onset Pompe disease patients

scientific article

Loss of CD38 correlates with simultaneous up-regulation of human leukocyte antigen-DR in benign prostatic glands, but not in fetal or androgen-ablated glands, and is strongly related to gland atrophy

scientific article published on 01 March 2003

Loss of immune tolerance to IL-2 in type 1 diabetes

scientific article published on 06 October 2016

Low-dose interleukin-2 fosters a dose-dependent regulatory T cell tuned milieu in T1D patients

scientific article published on 26 January 2015

MHC Class II tetramers and the pursuit of antigen-specific T cells: define, deviate, delete

scientific article published on March 2004

MHC class II tetramers made from isolated recombinant α and β chains refolded with affinity-tagged peptides

scientific article

Materno-Fetal Transfer of Preproinsulin Through the Neonatal Fc Receptor Prevents Autoimmune Diabetes

scientific article published on 27 April 2015

Measurement of CD8 T cell responses in human type 1 diabetes

scientific article published on December 2008

Mesenchymal stem cells protect NOD mice from diabetes by inducing regulatory T cells

scientific article published on 7 May 2009

Navigating diabetes-related immune epitope data: resources and tools provided by the Immune Epitope Database (IEDB)

scientific article

Of bugs and men: antigen-fortified Lactoccoccus lactis for type 1 diabetes immunotherapy

scientific article published on 01 August 2014

Pathogenic and regulatory T cells in type 1 diabetes: losing self-control, restoring it, and how to take the temperature

scientific article published on October 2011

Presumption of guilt for T cells in type 1 diabetes: lead culprits or partners in crime depending on age of onset?

scientific article published on 21 October 2020

Presumption of innocence for beta cells: why are they vulnerable autoimmune targets in type 1 diabetes?

scientific article published on 07 September 2020

Priming of Qualitatively Superior Human Effector CD8+ T Cells Using TLR8 Ligand Combined with FLT3 Ligand

scientific article published on 25 November 2015

Reduced naïve CD8(+) T-cell priming efficacy in elderly adults

scientific article

Regulation of immune responses to protein therapeutics by transplacental induction of T cell tolerance

scientific article published in February 2015

Regulatory T cell phenotype and function 4 years after GAD-alum treatment in children with type 1 diabetes

scientific article published in June 2013

Retinoids in breast cancer prevention and treatment. A review of the literature.

scientific article

Serum-free culture medium and IL-7 costimulation increase the sensitivity of ELISpot detection

scientific article published on 29 January 2008

Short-term subcutaneous insulin treatment delays but does not prevent diabetes in NOD mice

scientific article published on 01 June 2012

Signaling through CD38 induces NK cell activation

scientific article published in April 2001

Single insulin-specific CD8+ T cells show characteristic gene expression profiles in human type 1 diabetes

scientific article published on 13 October 2011

T cell recognition of autoantigens in human type 1 diabetes: clinical perspectives

scientific article published on 19 July 2011

T cells in the pathogenesis of type 1 diabetes

scientific article published on April 2008

T cells recognizing a peptide contaminant undetectable by mass spectrometry.

scientific article

T-Cell Epitopes and Neo-epitopes in Type 1 Diabetes: A Comprehensive Update and Reappraisal

scientific article published on 01 July 2020

Targeting T lymphocytes for immune monitoring and intervention in autoimmune diabetes

scientific article

The frequency and immunodominance of islet-specific CD8+ T-cell responses change after type 1 diabetes diagnosis and treatment

scientific article published on 27 February 2008

Three sensitive assays do not provide evidence for circulating HuD-specific T cells in the blood of patients with paraneoplastic neurological syndromes with anti-Hu antibodies

scientific article

To B or not to B: (anti)bodies of evidence on the crime scene of type 1 diabetes?

scientific article published on August 2011

Viral infection prevents diabetes by inducing regulatory T cells through NKT cell-plasmacytoid dendritic cell interplay.

scientific article

Worsening of hypertension in a pregnant woman with renal arteriovenous malformation: a successful superselective embolization after delivery

scientific article published on 01 September 2003

Zinc transporter (ZnT)8(186-194) is an immunodominant CD8+ T cell epitope in HLA-A2+ type 1 diabetic patients.

scientific article published on 20 April 2012

acDCs enhance human antigen-specific T-cell responses

scientific article published on 28 June 2011

β-cell Mass in Nondiabetic Autoantibody-Positive Subjects: An Analysis Based on the Network for Pancreatic Organ Donors Database

scientific article published on 01 February 2016

Paulina is supported by:

About Paulina

Help