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List of works by Meinrad Busslinger

A Kinase-Independent Function of CDK6 Links the Cell Cycle to Tumor Angiogenesis

scientific article published in August 2016

A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse

scientific article

A kinase-independent function of CDK6 links the cell cycle to tumor angiogenesis

scientific article

A novel B-cell lineage-specific transcription factor present at early but not late stages of differentiation

scientific article published on May 1990

A regulatory sequence near the 3' end of sea urchin histone genes

scientific article published on July 1979

A selective transcriptional induction system for mammalian cells based on Gal4-estrogen receptor fusion proteins

scientific article

Activated Notch counteracts Ikaros tumor suppression in mouse and human T-cell acute lymphoblastic leukemia

scientific article published on 6 February 2015

Activation of an inducible c-FosER fusion protein causes loss of epithelial polarity and triggers epithelial-fibroblastoid cell conversion

scientific article published on December 1992

Activation-induced cytidine deaminase expression in CD4+ T cells is associated with a unique IL-10-producing subset that increases with age

scientific article (publication date: 2011)

Alternatively spliced insertions in the paired domain restrict the DNA sequence specificity of Pax6 and Pax8.

scientific article

An intragenic TaqI RFLP at the PAX5 locus

scientific article published on 01 April 1994

Anabolism-Associated Mitochondrial Stasis Driving Lymphocyte Differentiation over Self-Renewal ⬇️

scientific article published on December 2016

Aspects of the regulation of histone genes

scientific article published on May 1978

B young again

scientific article

B-lymphoid cells with attributes of dendritic cells regulate T cells via indoleamine 2,3-dioxygenase

scientific article

Beta + thalassemia: aberrant splicing results from a single point mutation in an intron

scientific article published in December 1981

Bhlhe40 and Bhlhe41 transcription factors regulate alveolar macrophage self-renewal and identity

scientific article published on 15 August 2019

Blimp-1 controls plasma cell function through the regulation of immunoglobulin secretion and the unfolded protein response

scientific article published on 18 January 2016

CTCF-binding elements mediate control of V(D)J recombination

scientific article published on 11 September 2011

CXCR5(+) follicular cytotoxic T cells control viral infection in B cell follicles

scientific article published on 3 August 2016

Caffeine-induced diuresis and natriuresis is independent of renal tubular NHE3

scientific article

Chromosomal localization of seven PAX genes and cloning of a novel family member, PAX-9

scientific article (publication date: April 1993)

Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP

scientific article published on 01 December 1994

Conserved biological function between Pax-2 and Pax-5 in midbrain and cerebellum development: evidence from targeted mutations

scientific article published on December 1997

Control of B-1a cell development by instructive BCR signaling

scientific article published on 3 February 2018

Control of antigen receptor diversity through spatial regulation of V(D)J recombination

scientific article published in January 2013

Control of pre-BCR signaling by Pax5-dependent activation of the BLNK gene

scientific article published in October 2002

Conversion of mature B cells into T cells by dedifferentiation to uncommitted progenitors

scientific article

Cooperation of Pax2 and Pax5 in midbrain and cerebellum development

scientific article

Corecruitment of the Grg4 repressor by PU.1 is critical for Pax5-mediated repression of B-cell-specific genes

scientific article published on 20 February 2004

DNA methylation and the regulation of globin gene expression

scientific article published on 01 August 1983

DNA sequence recognition by Pax proteins: bipartite structure of the paired domain and its binding site

scientific article published in October 1993

Dangerous liaisons: spermatozoa as natural vectors for foreign DNA?

scientific article published on June 1989

Deregulated expression of PAX5 in medulloblastoma

scientific article

Deregulation of PAX-5 by translocation of the Emu enhancer of the IgH locus adjacent to two alternative PAX-5 promoters in a diffuse large-cell lymphoma

scientific article

Derivation of 2 categories of plasmacytoid dendritic cells in murine bone marrow

scientific article published on 22 February 2005

Developmental and tissue-specific regulation of a novel transcription factor of the sea urchin

scientific article published on May 1989

Developmental plasticity of lymphocytes

scientific article published on April 2008

Developmental regulation of micro-injected histone genes in sea urchin embryos

scientific article published in May 1988

Differential requirement for Nfil3 during NK cell development.

scientific article

Differentiation of type 1 ILCs from a common progenitor to all helper-like innate lymphoid cell lineages

scientific article published in April 2014

Differentiation, dedifferentiation, and redifferentiation of B-lineage lymphocytes: roles of the surrogate light chain and the Pax5 gene

scientific article

Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch

scientific journal article

Distinct promoters mediate the regulation of Ebf1 gene expression by interleukin-7 and Pax5

scientific article

Distinct regulators control the expression of the mid-hindbrain organizer signal FGF8.

scientific article published in December 2001

Early function of Pax5 (BSAP) before the pre-B cell receptor stage of B lymphopoiesis

scientific article published on August 1998

Epigenetic Control of Immunity

Epigenetic control of immunity

scientific article

Epigenetic regulation of brain region-specific microglia clearance activity.

scientific article published on 23 July 2018

Epigenetic silencing of the c-fms locus during B-lymphopoiesis occurs in discrete steps and is reversible.

scientific article published on 14 October 2004

Erratum: Corrigendum: RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci

scholarly article published in Nature Immunology

Erratum: Corrigendum: RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci

scholarly article published in Nature Immunology

Erythropoiesis and globin switching in compound Klf1::Bcl11a mutant mice

scientific article published on 29 January 2013

Essential functions of Pax5 (BSAP) in pro-B cell development: difference between fetal and adult B lymphopoiesis and reduced V-to-DJ recombination at the IgH locus

scientific article published in February 1997

Essential role for the transcription factor Bhlhe41 in regulating the development, self-renewal and BCR repertoire of B-1a cells.

scientific article published on 27 February 2017

Essential role of EBF1 in the generation and function of distinct mature B cell types

scientific article published on 2 April 2012

Fidelity and infidelity in commitment to B-lymphocyte lineage development

scientific article

Flexible long-range loops in the VH gene region of the Igh locus facilitate the generation of a diverse antibody repertoire

scientific article published on August 2013

GABAergic neurons regulate lateral ventricular development via transcription factor Pax5

scientific journal article

GATA-3 regulates the self-renewal of long-term hematopoietic stem cells

scientific article published on 25 August 2013

Gene repression by Pax5 in B cells is essential for blood cell homeostasis and is reversed in plasma cells

scientific article published in March 2006

Hematopoietic precursor cells transiently reestablish permissiveness for X inactivation

scientific article

Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes

scientific journal article

Hormone-dependent transcriptional regulation and cellular transformation by Fos-steroid receptor fusion proteins

scientific article published on June 1991

ICE-proteases mediate HTLV-I Tax-induced apoptotic T-cell death.

scientific article published in May 1997

Id2-mediated inhibition of E2A represses memory CD8+ T cell differentiation

scientific article

Identification of BSAP (Pax-5) target genes in early B-cell development by loss- and gain-of-function experiments

scientific article published on April 1998

Identification of Pax2-regulated genes by expression profiling of the mid-hindbrain organizer region

scientific article

Ikaros prevents autoimmunity by controlling anergy and Toll-like receptor signaling in B cells

scientific article published on 07 October 2019

In vitro differentiation of murine embryonic stem cells toward a renal lineage

scientific article published on 5 February 2007

Instructive role of the transcription factor E2A in early B lymphopoiesis and germinal center B cell development

scientific article

Isolation and amino acid sequence analysis reveal an ancient evolutionary origin of the cleavage stage (CS) histones of the sea urchin

scientific article published in August 1997

Lack of nuclear factor-kappa B2/p100 causes a RelB-dependent block in early B lymphopoiesis

scientific article published on 27 May 2008

Life beyond cleavage: the case of Ago2 and hematopoiesis

scientific article published on August 2007

Lineage commitment in lymphopoiesis

scientific article

Locus 'decontraction' and centromeric recruitment contribute to allelic exclusion of the immunoglobulin heavy-chain gene

scientific article published on 05 December 2004

Long-term in vivo reconstitution of T-cell development by Pax5-deficient B-cell progenitors

scientific article

Loss- and gain-of-function mutations reveal an important role of BSAP (Pax-5) at the start and end of B cell differentiation

scientific article published in April 1998

MUCOSAL IMMUNOLOGY. The microbiota regulates type 2 immunity through RORγt⁺ T cells

scientific article published on 9 July 2015

Mcl-1 is essential for germinal center formation and B cell memory

scientific article

Modeling Renal Cell Carcinoma in Mice: Bap1 and Pbrm1 Inactivation Drive Tumor Grade

scientific article published on 4 May 2017

Molecular cloning and characterization of a human PAX-7 cDNA expressed in normal and neoplastic myocytes

scientific article

Molecular functions of the transcription factors E2A and E2-2 in controlling germinal center B cell and plasma cell development

scientific article

Molecular role of the PAX5-ETV6 oncoprotein in promoting B-cell acute lymphoblastic leukemia

scientific article published on 20 February 2017

Monoallelic expression of Pax5: a paradigm for the haploinsufficiency of mammalian Pax genes?

scientific article

Multifunctional role of the transcription factor Blimp-1 in coordinating plasma cell differentiation

scientific article published on 18 January 2016

Mutually exclusive interaction of the CCAAT-binding factor and of a displacement protein with overlapping sequences of a histone gene promoter

article

Myeloid lineage switch of Pax5 mutant but not wild-type B cell progenitors by C/EBPalpha and GATA factors

scientific article

NK Cell-Specific Gata3 Ablation Identifies the Maturation Program Required for Bone Marrow Exit and Control of Proliferation

scientific article

Nephric lineage specification by Pax2 and Pax8

scientific journal article

Oncogenic role of Pax5 in the T-lymphoid lineage upon ectopic expression from the immunoglobulin heavy-chain locus

scientific article published on 12 September 2006

Opposing roles of polycomb repressive complexes in hematopoietic stem and progenitor cells

scientific article published on 5 May 2010

PAX8 mutations associated with congenital hypothyroidism caused by thyroid dysgenesis

scientific article

PU.1 cooperates with IRF4 and IRF8 to suppress pre-B-cell leukemia

scientific article published on 02 March 2016

Paul Ehrlich (1854-1915) and His Contributions to the Foundation and Birth of Translational Medicine.

scientific article

Pax 2/8-regulated Gata 3 expression is necessary for morphogenesis and guidance of the nephric duct in the developing kidney

scientific journal article

Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis

scientific article

Pax2 and Pax8 cooperate in mouse inner ear morphogenesis and innervation

scientific article

Pax2/5 and Pax6 subdivide the early neural tube into three domains

scientific article published in April 1999

Pax5 determines the identity of B cells from the beginning to the end of B-lymphopoiesis

scientific article

Pax5 induces V-to-DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene

scientific article published on February 2004

Pax5 promotes B lymphopoiesis and blocks T cell development by repressing Notch1.

scientific article published in December 2002

Pax5/BSAP maintains the identity of B cells in late B lymphopoiesis

scientific article published in June 2001

Pax5: a master regulator of B cell development and leukemogenesis

scientific article published on January 2011

Pax5: the guardian of B cell identity and function

scientific article published on May 2007

Polycomb repression complex 2 is required for the maintenance of retinal progenitor cells and balanced retinal differentiation

scientific article published on 11 November 2017

Postnatal development of the murine cerebellar cortex: formation and early dispersal of basket, stellate and Golgi neurons

scientific article published in July 2006

Precocious expression of Blimp1 in B cells causes autoimmune disease with increased self-reactive plasma cells

scientific article published on 29 November 2018

Promoter of a somatic histone H2B gene of the sea urchin

scientific article published on May 1988

RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci

scientific journal article

Rapid in vivo analysis of mutant forms of the LAT adaptor using Pax5-Lat double-deficient pro-B cells

scientific article

Regulation of DNA replication within the immunoglobulin heavy-chain locus during B cell commitment

scientific article

Regulation of GATA-3 expression during CD4 lineage differentiation.

scientific article

Retrotransposon derepression leads to activation of the unfolded protein response and apoptosis in pro-B cells

scientific article

Reversible contraction by looping of the Tcra and Tcrb loci in rearranging thymocytes

scientific article published on 04 March 2007

Reversion of B cell commitment upon loss of Pax5 expression

scientific article published in July 2002

Role of STAT5 in controlling cell survival and immunoglobulin gene recombination during pro-B cell development

scientific article published on 29 November 2009

Rotational diffusion of band 3 proteins in the human erythrocyte membrane

scientific article published in Nature

SGLT2 inhibition and renal urate excretion: role of luminal glucose, GLUT9, and URAT1

scientific article published on 14 November 2018

SSCP/SacI polymorphism in the PAX5 gene

scientific article published in May 1994

STAT5 in B cell development and leukemia

scientific article published on 11 March 2010

Spatial Regulation of V-(D)J Recombination at Antigen Receptor Loci.

scientific article published on 13 August 2015

Stage-specific control of early B cell development by the transcription factor Ikaros

scientific article published on 9 February 2014

Stepwise activation of enhancer and promoter regions of the B cell commitment gene Pax5 in early lymphopoiesis

scientific article published on 2 April 2009

Synthesis of sperm and late histone cDNAs of the sea urchin with a primer complementary to the conserved 3' terminal palindrome: evidence for tissue-specific and more general histone gene variants

scientific article published on September 1985

The B-cell identity factor Pax5 regulates distinct transcriptional programmes in early and late B lymphopoiesis

scientific article published on 5 June 2012

The Helix-Loop-Helix Protein ID2 Governs NK Cell Fate by Tuning Their Sensitivity to Interleukin-15.

scientific article published on 9 January 2016

The PAX5 gene: a linkage and mutation analysis in candidate human primary immunodeficiencies

scientific article published on January 1995

The characterization of novel Pax genes of the sea urchin and Drosophila reveal an ancient evolutionary origin of the Pax2/5/8 subfamily

scientific article published in October 1997

The distal V(H) gene cluster of the Igh locus contains distinct regulatory elements with Pax5 transcription factor-dependent activity in pro-B cells

scientific article

The estrogen-dependent c-JunER protein causes a reversible loss of mammary epithelial cell polarity involving a destabilization of adherens junctions

scientific article

The mechanism of repression of the myeloid-specific c-fms gene by Pax5 during B lineage restriction

scientific article

The metabolite BH4 controls T cell proliferation in autoimmunity and cancer

scientific article published in Nature

The molecular basis of B-cell lineage commitment

scientific article

The protein CDP, but not CP1, footprints on the CCAAT region of the γ-globin gene in unfractionated B-cell extracts

article

The role of BSAP (Pax-5) in B-cell development

scientific article published on October 1995

The sequence GGCmCGG is resistant to MspI cleavage

scientific article published on June 1983

The testis-specific octamer-binding protein of the sea urchin has a molecular weight of 85 kDa.

scientific article published on September 1989

The transcription factor GATA-3 controls cell fate and maintenance of type 2 innate lymphoid cells.

scientific article published on 11 October 2012

The transcription factor Pax5 regulates its target genes by recruiting chromatin-modifying proteins in committed B cells

scientific article (publication date: 6 May 2011)

The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells

scientific article

The transcriptional repressor CDP (Cutl1) is essential for epithelial cell differentiation of the lung and the hair follicle

scientific journal article

Thymic B Cells Are Licensed to Present Self Antigens for Central T Cell Tolerance Induction

scientific article published on 9 June 2015

Tissue-specific expression of cre recombinase from the Pax8 locus

scientific article published in March 2004

Tlx3 and Tlx1 are post-mitotic selector genes determining glutamatergic over GABAergic cell fates

scientific journal article

Transcription factor Pax5 activates the chromatin of key genes involved in B cell signaling, adhesion, migration, and immune function

scientific article published on 19 July 2007

Transcription factor YY1 is essential for regulation of the Th2 cytokine locus and for Th2 cell differentiation

scientific article published on 17 December 2012

Transcription termination and 3' processing: the end is in site!

scientific article (publication date: June 1985)

Transcriptional control of B-cell development

scientific article

Transcriptional control of early B cell development

scientific article published on January 2004

Transcriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho family

scientific article

Ubiquitous and gene-specific regulatory 5' sequences in a sea urchin histone DNA clone coding for histone protein variants

scientific article published on March 1980

Wapl repression by Pax5 promotes V gene recombination by Igh loop extrusion

scientific article published on 01 July 2020

twin of eyeless, a second Pax-6 gene of Drosophila, acts upstream of eyeless in the control of eye development

scientific article published in March 1999

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