List of works - Sonja Sucic

A cytosolic relay of heat shock proteins HSP70-1A and HSP90β monitors the folding trajectory of the serotonin transporter

scientific article published on 8 September 2014

A salt bridge linking the first intracellular loop with the C terminus facilitates the folding of the serotonin transporter

scientific article published on 13 April 2015

An unfolding story: Small molecules remedy misfolded monoamine transporters.

scientific article published on 7 September 2017

Axonal targeting of the serotonin transporter in cultured rat dorsal raphe neurons is specified by SEC24C-dependent export from the endoplasmic reticulum

scientific article published in April 2014

Big Lessons from Tiny Flies: Drosophila Melanogaster as a Model to Explore Dysfunction of Dopaminergic and Serotonergic Neurotransmitter Systems

scholarly article published 22 May 2018

Big Lessons from Tiny Flies: as a Model to Explore Dysfunction of Dopaminergic and Serotonergic Neurotransmitter Systems

scholarly article by Ameya Kasture et al published 16 June 2018 in International Journal of Molecular Sciences

Ca(2+)/calmodulin-dependent protein kinase IIα (αCaMKII) controls the activity of the dopamine transporter: implications for Angelman syndrome.

scientific article published on 9 July 2012

Calmodulin kinase II regulates amphetamine-induced reverse transport in dopamine and serotonin transporters

scientific article published on 17 September 2012

Cell death mechanisms at the maternal-fetal interface: insights into the role of granulysin

scientific article

Characterising the interaction between the COPII component SEC24C and the human serotonin transporter

scientific article published on 5 September 2011

Classical Radioligand Uptake and Binding Methods in Transporter Research: An Emphasis on the Monoamine Neurotransmitter Transporters

scholarly article by Sonja Sucic & Heinz Bönisch published 2016 in Neuromethods

Comparison of the β-Adrenergic Receptor Antagonists Landiolol and Esmolol: Receptor Selectivity, Partial Agonism, and Pharmacochaperoning Actions

scientific article published on 22 July 2016

Concentrative ER export of the serotonin transporter relies exclusively on an interaction with Sec24C.

scientific article

Conformational state interactions provide clues to the pharmacochaperone potential of serotonin transporter partial substrates

scientific article published on 23 August 2017

Corrigendum: STAT3 controls IL6-dependent regulation of serotonin transporter function and depression-like behaviour

scientific article published on 15 July 2015

Differential regulation of amphetamine-induced serotonergic and dopaminergic efflux by syntaxin 1A.

scientific article

Distinct contribution of axonal and somatodendritic serotonin transporters in drosophila olfaction

scientific article published on 06 March 2019

First Trimester Pregnancy Decidual Natural Killer Cells Contain and Spontaneously Release High Quantities of Granulysin

scientific article published on 27 May 2011

Functional Rescue of a Misfolded Drosophila melanogaster Dopamine Transporter Mutant Associated with a Sleepless Phenotype by Pharmacological Chaperones.

scientific article

Functional significance of a highly conserved glutamate residue of the human noradrenaline transporter

scientific article

How does the carboxyl terminus assist folding and ER export of the serotonin transporter?

scientific article published on 17 September 2012

Investigation of the functional roles of the MELAL and GQXXRXG motifs of the human noradrenaline transporter using cysteine mutants

scientific article published on 3 November 2006

LAPTM4A interacts with hOCT2 and regulates its endocytotic recruitment

scientific article published on 08 May 2011

Ligand Selectivity among the Dopamine and Serotonin Transporters Specified by the Forward Binding Reaction

scientific article

Mutations in the amino-terminus impair amphetamine-induced efflux by inducing inward-facing conformations of the serotonin transporter

scholarly article by Sonja Sucic et al published 2009 in BMC Pharmacology

Nanopharmacological Force Sensing to Reveal Allosteric Coupling in Transporter Binding Sites

scientific article published on 22 December 2015

Pharmacochaperoning in a Drosophila model system rescues human dopamine transporter variants associated with infantile/juvenile parkinsonism

scientific article published on 29 September 2017

Relax, Cool Down and Scaffold: How to Restore Surface Expression of Folding-Deficient Mutant GPCRs and SLC6 Transporters

scientific article published on 14 November 2017

Rescue by 4-phenylbutyrate of several misfolded creatine transporter-1 variants linked to the creatine transporter deficiency syndrome

scientific article published on 15 March 2019

Roles of transmembrane domain 2 and the first intracellular loop in human noradrenaline transporter function: pharmacological and SCAM analysis

scientific article published on 10 August 2005

SLC6 Transporter Folding Diseases and Pharmacochaperoning.

scientific article published on 31 October 2017

STAT3 controls IL6-dependent regulation of serotonin transporter function and depression-like behavior

scientific article

Several adaptor proteins promote intracellular localisation of the transporter MRP4/ABCC4 in platelets and haematopoietic cells

scientific article published on 20 October 2016

Standardized phytotherapic extracts rescue anomalous locomotion and electrophysiological responses of TDP-43 Drosophila melanogaster model of ALS

scientific article published in Scientific Reports

Switching the clientele: a lysine residing in the C terminus of the serotonin transporter specifies its preference for the coat protein complex II component SEC24C

scientific article published on 3 January 2013

The N Terminus Specifies the Switch between Transport Modes of the Human Serotonin Transporter

scientific article published on 19 January 2017

The N terminus of monoamine transporters is a lever required for the action of amphetamines

scientific article

The N-terminus acts as a lever to support amphetamine-induced substrate efflux by the serotonin transporter

The cysteines of the extracellular loop are crucial for trafficking of human organic cation transporter 2 to the plasma membrane and are involved in oligomerization

scientific article published on 15 November 2011

The high-affinity binding site for tricyclic antidepressants resides in the outer vestibule of the serotonin transporter

scientific article

The role of the conserved GXXXRXG motif in the expression and function of the human norepinephrine transporter

scientific article published on December 2002

The serotonin transporter is an exclusive client of the coat protein complex II (COPII) component SEC24C.

scientific article

Trafficking of the amino acid transporter B0,+ (SLC6A14) to the plasma membrane involves an exclusive interaction with SEC24C for its exit from the endoplasmic reticulum

scientific article published on 14 November 2018

Truncations in the amino terminus reveal a region key to supporting amphetamine-induced efflux by the human serotonin transporter

scholarly article by Sonja Sucic et al published 2011 in BMC Pharmacology

When transporters fail to be transported: how to rescue folding-deficient SLC6 transporters

scientific article published on 01 December 2016

List of works by Sonja Sucic

A cytosolic relay of heat shock proteins HSP70-1A and HSP90β monitors the folding trajectory of the serotonin transporter

A salt bridge linking the first intracellular loop with the C terminus facilitates the folding of the serotonin transporter

An unfolding story: Small molecules remedy misfolded monoamine transporters.

Axonal targeting of the serotonin transporter in cultured rat dorsal raphe neurons is specified by SEC24C-dependent export from the endoplasmic reticulum

Big Lessons from Tiny Flies: Drosophila Melanogaster as a Model to Explore Dysfunction of Dopaminergic and Serotonergic Neurotransmitter Systems

Big Lessons from Tiny Flies: as a Model to Explore Dysfunction of Dopaminergic and Serotonergic Neurotransmitter Systems

Ca(2+)/calmodulin-dependent protein kinase IIα (αCaMKII) controls the activity of the dopamine transporter: implications for Angelman syndrome.

Calmodulin kinase II regulates amphetamine-induced reverse transport in dopamine and serotonin transporters

Cell death mechanisms at the maternal-fetal interface: insights into the role of granulysin

Characterising the interaction between the COPII component SEC24C and the human serotonin transporter

Classical Radioligand Uptake and Binding Methods in Transporter Research: An Emphasis on the Monoamine Neurotransmitter Transporters

Comparison of the β-Adrenergic Receptor Antagonists Landiolol and Esmolol: Receptor Selectivity, Partial Agonism, and Pharmacochaperoning Actions

Concentrative ER export of the serotonin transporter relies exclusively on an interaction with Sec24C.

Conformational state interactions provide clues to the pharmacochaperone potential of serotonin transporter partial substrates

Corrigendum: STAT3 controls IL6-dependent regulation of serotonin transporter function and depression-like behaviour

Differential regulation of amphetamine-induced serotonergic and dopaminergic efflux by syntaxin 1A.

Distinct contribution of axonal and somatodendritic serotonin transporters in drosophila olfaction

First Trimester Pregnancy Decidual Natural Killer Cells Contain and Spontaneously Release High Quantities of Granulysin

Functional Rescue of a Misfolded Drosophila melanogaster Dopamine Transporter Mutant Associated with a Sleepless Phenotype by Pharmacological Chaperones.

Functional significance of a highly conserved glutamate residue of the human noradrenaline transporter

How does the carboxyl terminus assist folding and ER export of the serotonin transporter?

Investigation of the functional roles of the MELAL and GQXXRXG motifs of the human noradrenaline transporter using cysteine mutants

LAPTM4A interacts with hOCT2 and regulates its endocytotic recruitment

Ligand Selectivity among the Dopamine and Serotonin Transporters Specified by the Forward Binding Reaction

Mutations in the amino-terminus impair amphetamine-induced efflux by inducing inward-facing conformations of the serotonin transporter

Nanopharmacological Force Sensing to Reveal Allosteric Coupling in Transporter Binding Sites

Pharmacochaperoning in a Drosophila model system rescues human dopamine transporter variants associated with infantile/juvenile parkinsonism

Relax, Cool Down and Scaffold: How to Restore Surface Expression of Folding-Deficient Mutant GPCRs and SLC6 Transporters

Rescue by 4-phenylbutyrate of several misfolded creatine transporter-1 variants linked to the creatine transporter deficiency syndrome

Roles of transmembrane domain 2 and the first intracellular loop in human noradrenaline transporter function: pharmacological and SCAM analysis

SLC6 Transporter Folding Diseases and Pharmacochaperoning.

STAT3 controls IL6-dependent regulation of serotonin transporter function and depression-like behavior

Several adaptor proteins promote intracellular localisation of the transporter MRP4/ABCC4 in platelets and haematopoietic cells

Standardized phytotherapic extracts rescue anomalous locomotion and electrophysiological responses of TDP-43 Drosophila melanogaster model of ALS

Switching the clientele: a lysine residing in the C terminus of the serotonin transporter specifies its preference for the coat protein complex II component SEC24C

The N Terminus Specifies the Switch between Transport Modes of the Human Serotonin Transporter

The N terminus of monoamine transporters is a lever required for the action of amphetamines

The N-terminus acts as a lever to support amphetamine-induced substrate efflux by the serotonin transporter

The cysteines of the extracellular loop are crucial for trafficking of human organic cation transporter 2 to the plasma membrane and are involved in oligomerization

The high-affinity binding site for tricyclic antidepressants resides in the outer vestibule of the serotonin transporter

The role of the conserved GXXXRXG motif in the expression and function of the human norepinephrine transporter

The serotonin transporter is an exclusive client of the coat protein complex II (COPII) component SEC24C.

Trafficking of the amino acid transporter B0,+ (SLC6A14) to the plasma membrane involves an exclusive interaction with SEC24C for its exit from the endoplasmic reticulum

Truncations in the amino terminus reveal a region key to supporting amphetamine-induced efflux by the human serotonin transporter

When transporters fail to be transported: how to rescue folding-deficient SLC6 transporters