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List of works by Greg M. Thurber

"Standing by" for Bystander Effects: Dual-Isotope Imaging of Antibody-Drug Conjugate and Payload Distribution

scientific article published on 12 July 2018

18F labeled nanoparticles for in vivo PET-CT imaging

scientific article published on February 2009

A Helix-Stabilizing Linker Improves Subcutaneous Bioavailability of a Helical Peptide Independent of Linker Lipophilicity.

scientific article published on 21 June 2016

A mechanistic compartmental model for total antibody uptake in tumors

scientific article published on 6 September 2012

A systems approach for tumor pharmacokinetics

scientific article

Accurate measurement of pancreatic islet beta-cell mass using a second-generation fluorescent exendin-4 analog

scientific article

Advances in measuring single-cell pharmacology in vivo

scientific article

Antibody tumor penetration: transport opposed by systemic and antigen-mediated clearance.

scientific article published on 24 April 2008

Co-administered antibody improves penetration of antibody-dye conjugate into human cancers with implications for antibody-drug conjugates

scientific article published on 09 November 2020

Directed Evolution Using Stabilized Bacterial Peptide Display

scientific article published on 10 January 2020

Dual-purpose linker for alpha helix stabilization and imaging agent conjugation to glucagon-like peptide-1 receptor ligands.

scientific article

Effect of small-molecule modification on single-cell pharmacokinetics of PARP inhibitors

scientific article

Hybrid in vivo FMT-CT imaging of protease activity in atherosclerosis with customized nanosensors.

scientific article published on 16 July 2009

Improved Tumor Penetration and Single-Cell Targeting of Antibody Drug Conjugates Increases Anticancer Efficacy and Host Survival.

scientific article published on 7 December 2017

Kinetics of anti-carcinoembryonic antigen antibody internalization: effects of affinity, bivalency, and stability.

scientific article published on 12 April 2008

Mechanistic and quantitative insight into cell surface targeted molecular imaging agent design.

scientific article

Multichannel imaging to quantify four classes of pharmacokinetic distribution in tumors

scientific article

Multicolor fluorescent intravital live microscopy (FILM) for surgical tumor resection in a mouse xenograft model

scientific article (publication date: 30 November 2009)

Multiscale Modeling of Antibody-Drug Conjugates: Connecting Tissue and Cellular Distribution to Whole Animal Pharmacokinetics and Potential Implications for Efficacy.

scientific article published on 10 June 2016

Noise suppressed, multifocus image fusion for enhanced intraoperative navigation.

scientific article published on 6 August 2012

Ocular Toxicity Profile of ST-162 and ST-168 as Novel Bifunctional MEK/PI3K Inhibitors

scientific article published on 30 April 2018

Oral Administration and Detection of a Near-Infrared Molecular Imaging Agent in an Orthotopic Mouse Model for Breast Cancer Screening.

scientific article

Oral and Subcutaneous Administration of a Near-Infrared Fluorescent Molecular Imaging Agent Detects Inflammation in a Mouse Model of Rheumatoid Arthritis

scientific article published on 12 March 2019

Pharmacokinetic and Immunological Considerations for Expanding the Therapeutic Window of Next-Generation Antibody-Drug Conjugates

scientific article published on 01 October 2018

Population dynamics of islet-infiltrating cells in autoimmune diabetes.

scientific article

Practical Guide for Quantification of In Vivo Degradation Rates for Therapeutic Proteins with Single-Cell Resolution Using Fluorescence Ratio Imaging

scientific article published on 05 February 2020

Practical theoretic guidance for the design of tumor-targeting agents.

scientific article

Quantitative Impact of Plasma Clearance and Down-regulation on GLP-1 Receptor Molecular Imaging.

scientific article

Quantitative pharmacology in antibody-drug conjugate development: armed antibodies or targeted small molecules?

scientific article published in May 2018

Reactive polymer enables efficient in vivo bioorthogonal chemistry.

scientific article published on 12 March 2012

Residualization Rates of Near-Infrared Dyes for the Rational Design of Molecular Imaging Agents

scientific article

Single-cell and subcellular pharmacokinetic imaging allows insight into drug action in vivo.

scientific article

Structure-Guided Design and Initial Studies of a Bifunctional MEK/PI3K Inhibitor (ST-168).

scientific article

Systems Pharmacology Approach Toward the Design of Inhaled Formulations of Rifampicin and Isoniazid for Treatment of Tuberculosis

scientific article

Theoretic criteria for antibody penetration into solid tumors and micrometastases

scientific article published on 15 May 2007

Tracking Antibody Distribution with Near-Infrared Fluorescent Dyes: Impact of Dye Structure and Degree of Labeling on Plasma Clearance.

scientific article

Tumor Drug Penetration Measurements Could Be the Neglected Piece of the Personalized Cancer Treatment Puzzle

scientific article published on 06 October 2018