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List of works by Peter K. Sorger

3D Printed frames to enable reuse and improve the fit of N95 and KN95 respirators

scientific article published on 26 July 2020

A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade

article

A Crisis-Responsive Framework for Medical Device Development Applied to the COVID-19 Pandemic

publication published on 22 March 2021

A High Content Screen in Macrophages Identifies Small Molecule Modulators of STING-IRF3 and NFkB Signaling.

scientific article published on 19 March 2018

A Multi-center Study on the Reproducibility of Drug-Response Assays in Mammalian Cell Lines

scientific article published on 10 July 2019

A compendium of signals and responses triggered by prodeath and prosurvival cytokines

scientific article published on 18 July 2005

A curative combination cancer therapy achieves high fractional cell killing through low cross-resistance and drug additivity

scientific article published on 19 November 2019

A data-driven computational model of the ErbB receptor signaling network.

scientific article

A dual array-based approach to assess the abundance and posttranslational modification state of signaling proteins

scientific article

A dual role for Bub1 in the spindle checkpoint and chromosome congression

scientific article published on 31 March 2005

A dynamic view of the proteomic landscape during differentiation of ReNcell VM cells, an immortalized human neural progenitor line

scientific article published on 19 February 2019

A functional genomic screen identifies a role for TAO1 kinase in spindle-checkpoint signalling.

scientific article

A high-throughput quantitative multiplex kinase assay for monitoring information flow in signaling networks: application to sepsis-apoptosis

scientific article published on 26 June 2003

A multi-center study on factors influencing the reproducibility of in vitro drug-response studies

A multi-omic analysis of MCF10A cells provides a resource for integrative assessment of ligand-mediated molecular and phenotypic responses

scientific article published in 2022

A multiscale statistical mechanical framework integrates biophysical and genomic data to assemble cancer networks

scientific article

A multitargeted probe-based strategy to identify signaling vulnerabilities in cancers.

scientific article

A noncanonical Frizzled2 pathway regulates epithelial-mesenchymal transition and metastasis

scientific article

A proof of concept for biomarker-guided targeted therapy against ovarian cancer based on patient-derived tumor xenografts

scientific article published on 03 August 2020

A reductionist's systems biology: opinion

scientific article published in February 2005

A role for the Adenomatous Polyposis Coli protein in chromosome segregation

scientific article

A single-cell landscape of high-grade serous ovarian cancer

scientific article published on 22 June 2020

A systems model of signaling identifies a molecular basis set for cytokine-induced apoptosis

scientific article published in December 2005

Adaptation of Human iPSC-Derived Cardiomyocytes to Tyrosine Kinase Inhibitors Reduces Acute Cardiotoxicity via Metabolic Reprogramming

scientific article published on 08 May 2019

Adaptive informatics for multifactorial and high-content biological data

scientific article

Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly dividing de-differentiated state

scientific article published on 09 January 2017

Alternative drug sensitivity metrics improve preclinical cancer pharmacogenomics

scientific article published in June 2017

An expanding role for cell biologists in drug discovery and pharmacology.

scientific article

Analysis of SteraMist ionized hydrogen peroxide technology in the sterilization of N95 respirators and other PPE

scientific article published on 21 January 2021

Analysis of SteraMist ionized hydrogen peroxide technology in the sterilization of N95 respirators and other PPE: a quality improvement study

scientific article published on 23 April 2020

Analysis of growth factor signaling in genetically diverse breast cancer lines

scientific article

Analysis of kinesin motor function at budding yeast kinetochores.

scientific article

Analysis of mitosis and antimitotic drug responses in tumors by in vivo microscopy and single-cell pharmacodynamics.

scientific article published on 28 June 2011

Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities

scientific article

Assessing the filtration efficiency and regulatory status of N95s and nontraditional filtering face-piece respirators available during the COVID-19 pandemic

scientific article published on 29 July 2021

Assessing the quality of nontraditional N95 filtering face-piece respirators available during the COVID-19 pandemic

scientific article published on 27 July 2020

Author Correction: Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer

scientific article published on 18 May 2020

Automated assembly of molecular mechanisms at scale from text mining and curated databases

preprint published on 31 August 2022

Automatic fluorescent tag detection in 3D with super-resolution: application to the analysis of chromosome movement.

scientific article published in October 2002

BID preferentially activates BAK while BIM preferentially activates BAX, affecting chemotherapy response

scientific article

Bayesian network approach to cell signaling pathway modeling

scientific article

Biophysical prediction of protein-peptide interactions and signaling networks using machine learning

scientific article published on 06 January 2020

CRAN-11. MULTIPLEXED IMMUNOFLUORESCENCE REVEALS POTENTIAL PD-1/PD-L1 PATHWAY VULNERABILITIES IN CRANIOPHARYNGIOMA

Cell biology: the more MAD, the merrier

scientific article published on 01 March 2005

Cell stimulus and lysis in a microfluidic device with segmented gas-liquid flow

scientific article

Cells on chips

scientific article published on July 2006

Cells surviving fractional killing by TRAIL exhibit transient but sustainable resistance and inflammatory phenotypes

scientific article published on 22 May 2013

Centromeric chromatin and epigenetic effects in kinetochore assembly

scientific article published on 01 May 1998

Changing Mad2 levels affects chromosome segregation and spindle assembly checkpoint control in female mouse meiosis I.

scientific article

Channel Embedding for Informative Protein Identification from Highly Multiplexed Images

scientific article published on 29 September 2020

Chemical Biology Toolkit for DCLK1 Reveals Connection to RNA Processing

scientific article published on 04 August 2020

Cheminformatics Tools for Analyzing and Designing Optimized Small-Molecule Collections and Libraries

scientific article published on 04 April 2019

Chromosome instability induced by Mps1 and p53 mutation generates aggressive lymphomas exhibiting aneuploidy-induced stress.

scientific article

Classic and contemporary approaches to modeling biochemical reactions

scientific article

Clinical efficacy and molecular response correlates of the WEE1 inhibitor adavosertib combined with cisplatin in patients with metastatic triple-negative breast cancer (mTNBC)

scientific article published on 30 November 2020

Collecting and organizing systematic sets of protein data

scientific article

Combination Cancer Therapy Can Confer Benefit via Patient-to-Patient Variability without Drug Additivity or Synergy

scientific article published in December 2017

Common and cell-type specific responses to anti-cancer drugs revealed by high throughput transcript profiling.

scientific article published on 30 October 2017

Comparative autoregressive moving average analysis of kinetochore microtubule dynamics in yeast.

scientific article

Comparing signaling networks between normal and transformed hepatocytes using discrete logical models

scientific article

Comparing the Efficacy of Cancer Therapies between Subgroups in Basket Trials

scientific article published on 01 November 2020

Concurrent Dexamethasone Limits the Clinical Benefit of Immune Checkpoint Blockade in Glioblastoma

scientific article published on 25 November 2020

Conservation of protein abundance patterns reveals the regulatory architecture of the EGFR-MAPK pathway

scientific article published on 12 July 2016

Coupling cell division and cell death to microtubule dynamics

scientific article published on December 1997

Creating and analyzing pathway and protein interaction compendia for modelling signal transduction networks

scientific article (publication date: May 2012)

Crowdsourcing network inference: the DREAM predictive signaling network challenge

scientific article

Crystal Structure of the Yeast Inner Kinetochore Subunit Cep3p

scientific article

Cue-signal-response analysis of TNF-induced apoptosis by partial least squares regression of dynamic multivariate data

scientific article published in January 2004

Cyclic Immunofluorescence (CycIF), A Highly Multiplexed Method for Single-cell Imaging

scientific article

Cytokine-associated drug toxicity in human hepatocytes is associated with signaling network dysregulation

scientific article published on April 2010

Decision-tree based model analysis for efficient identification of parameter relations leading to different signaling states

scientific article (publication date: 2013)

Deletion of the MAD2L1 spindle assembly checkpoint gene is tolerated in mouse models of acute T-cell lymphoma and hepatocellular carcinoma

scientific article

Designing Drug-Response Experiments and Quantifying their Results.

scientific article

Development and Characterization of a Wee1 Kinase Degrader

scientific article published on 14 November 2019

Development of CDK2 and CDK5 Dual Degrader TMX-2172

scientific article published on 15 May 2020

Development of a Selective CDK7 Covalent Inhibitor Reveals Predominant Cell-Cycle Phenotype

scientific article published on 21 March 2019

Differentiable biology: using deep learning for biophysics-based and data-driven modeling of molecular mechanisms

scientific article published on 04 October 2021

Direct Lyapunov exponent analysis enables parametric study of transient signalling governing cell behaviour

scientific article

Discovering causal pathways linking genomic events to transcriptional states using Tied Diffusion Through Interacting Events (TieDIE).

scientific article published on 27 August 2013

Discovery and resistance mechanism of a selective CDK12 degrader

scientific article published on 22 March 2021

Discovery of Covalent CDK14 Inhibitors with Pan-TAIRE Family Specificity

scientific article published on 28 March 2019

Discovery of Potent and Selective Covalent Inhibitors of JNK

scientific article published on 27 January 2012

Discrete logic modelling as a means to link protein signalling networks with functional analysis of mammalian signal transduction

scientific article

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

scientific article published on April 2016

Electronic detection of DNA by its intrinsic molecular charge

scientific article

Elevated GM-CSF and IL-1beta levels compromise the ability of p38 MAPK inhibitors to modulate TNFalpha levels in the human monocytic/macrophage U937 cell line

scientific article published on 9 July 2010

Encoding Growth Factor Identity in the Temporal Dynamics of FOXO3 under the Combinatorial Control of ERK and AKT Kinases.

scientific article

Evolution of delayed resistance to immunotherapy in a melanoma responder

scientific article published on 03 May 2021

Exceptional response and multisystem autoimmune-like toxicities associated with the same T cell clone in a patient with uveal melanoma treated with immune checkpoint inhibitors

article

Exploring the contextual sensitivity of factors that determine cell-to-cell variability in receptor-mediated apoptosis

scientific article

Facetto: Combining Unsupervised and Supervised Learning for Hierarchical Phenotype Analysis in Multi-Channel Image Data

scientific article published on 10 September 2019

Factors required for the binding of reassembled yeast kinetochores to microtubules in vitro.

scientific article

Failure analysis of clinical trials to test the amyloid hypothesis

scientific article

FamPlex: a resource for entity recognition and relationship resolution of human protein families and complexes in biomedical text mining.

scientific article published on 28 June 2018

Fibroblast-tumor cell signaling limits HER2 kinase therapy response via activation of MTOR and antiapoptotic pathways

scientific article published on 29 June 2020

Fides: Reliable trust-region optimization for parameter estimation of ordinary differential equation models

scientific article published on 13 July 2022

Flexible informatics for linking experimental data to mathematical models via DataRail

scientific article

Fractional killing arises from cell-to-cell variability in overcoming a caspase activity threshold

scientific article published on 7 May 2015

From word models to executable models of signaling networks using automated assembly.

scientific article

Fundamental trade-offs between information flow in single cells and cellular populations.

scientific article published on 12 May 2017

Fuzzy logic analysis of kinase pathway crosstalk in TNF/EGF/insulin-induced signaling

scientific article

GRcalculator: an online tool for calculating and mining dose-response data.

scientific article published on 24 October 2017

Genetic selection of peptide inhibitors of biological pathways.

scientific article

Genome-encoded cytoplasmic double-stranded RNAs, found in <i>C9ORF72</i> ALS-FTD brain, propagate neuronal loss

scientific article published on 01 July 2021

Growth rate inhibition metrics correct for confounders in measuring sensitivity to cancer drugs

scientific article

HAND1 and BARX1 Act as Transcriptional and Anatomic Determinants of Malignancy in Gastrointestinal Stromal Tumor ⬇️

scientific article published on 15 January 2021

HSF1 phase transition mediates stress adaptation and cell fate decisions

scientific article published on 03 February 2020

Heat shock factor and the heat shock response

scientific article

Heterogeneity and Clonal Evolution of Acquired PARP Inhibitor Resistance in <i>TP53-</i> and <i>BRCA1</i>-Deficient Cells

scientific article published on 29 January 2021

Hierarchical assembly of the budding yeast kinetochore from multiple subcomplexes

scientific article

Highly multiplexed imaging of single cells using a high-throughput cyclic immunofluorescence method.

scientific article

Highly multiplexed immunofluorescence images and single-cell data of immune markers in tonsil and lung cancer

scientific article published on 17 December 2019

Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes

scientific article published on 11 July 2018

Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes

INDRA-IPM: interactive pathway modeling using natural language with automated assembly

scientific article published on 01 November 2019

INNV-13. ALLELE: A CONSORTIUM FOR PROSPECTIVE GENOMICS AND FUNCTIONAL DIAGNOSTICS TO GUIDE PATIENT CARE AND TRIAL ANALYSIS IN NEWLY-DIAGNOSED GLIOBLASTOMA

Identification of essential components of the S. cerevisiae kinetochore

scientific article published in May 1993

Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer

scientific article published on 19 March 2020

Impaired SHP2-mediated extracellular signal-regulated kinase activation contributes to gefitinib sensitivity of lung cancer cells with epidermal growth factor receptor-activating mutations

scientific article published on 20 April 2010

In vitro assays for studying Saccharomyces cerevisiae kinetochore activity

scientific article published on 01 January 1999

Inferring reaction network structure from single-cell, multiplex data, using toric systems theory

scientific article published on 06 December 2019

Inflammatory but not mitogenic contexts prime synovial fibroblasts for compensatory signaling responses to p38 inhibition

scientific article published on 6 March 2018

Informatics and quantitative analysis in biological imaging

scientific article

Inhibition of Haspin Kinase Promotes Cell-Intrinsic and Extrinsic Antitumor Activity

scientific article published on 27 December 2019

Input-output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data

scientific article

Integrating multi-omics data reveals function and therapeutic potential of deubiquitinating enzymes

preprint published on 09 August 2021

Integrating multi-omics data reveals function and therapeutic potential of deubiquitinating enzymes

scientific article published on 23 June 2022

Intra- and interdimeric caspase-8 self-cleavage controls strength and timing of CD95-induced apoptosis

scientific article

Kinetochores distinguish GTP from GDP forms of the microtubule lattice

scientific article published in Nature

Kinome-wide selectivity profiling of ATP-competitive mammalian target of rapamycin (mTOR) inhibitors and characterization of their binding kinetics

scientific article published on 5 January 2012

L1000CDS2: LINCS L1000 characteristic direction signatures search engine

scientific article

LINCS Canvas Browser: interactive web app to query, browse and interrogate LINCS L1000 gene expression signatures

scientific article

Leveraging Compound Promiscuity to Identify Targetable Cysteines within the Kinome

scientific article published on 11 April 2019

Live cell imaging of yeast.

scientific article

Logic-based models for the analysis of cell signaling networks

scientific article published on April 2010

Lyapunov exponents and phase diagrams reveal multi-factorial control over TRAIL-induced apoptosis

scientific article published on 22 November 2011

MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells

scientific journal article

MCMICRO: a scalable, modular image-processing pipeline for multiplexed tissue imaging

scientific article published on 25 November 2021

MITI minimum information guidelines for highly multiplexed tissue images

scientific article published on 01 March 2022

Machine learning identifies candidates for drug repurposing in Alzheimer's disease

scientific article published on 15 February 2021

Measuring Cancer Drug Sensitivity and Resistance in Cultured Cells

scientific article published on 19 June 2017

Measuring and Modeling Apoptosis in Single Cells ⬇️

scientific article published on March 18, 2011

Mechanistic model of <scp>MAPK</scp> signaling reveals how allostery and rewiring contribute to drug resistance

scientific article published in 2023

Metrics other than potency reveal systematic variation in responses to cancer drugs.

scientific article

Microfluidics closes in on point-of-care assays

scientific article published in December 2008

Minerva: a light-weight, narrative image browser for multiplexed tissue images

scientific article published on 15 October 2020

Mismatch repair deficiency in high-grade meningioma: a rare but recurrent event associated with dramatic immune activation and clinical response to PD-1 blockade

scientific article published on 27 November 2018

Misorientation and reduced stretching of aligned sister kinetochores promote chromosome missegregation in EB1- or APC-depleted cells.

scientific article published on 8 June 2006

Modeling a snap-action, variable-delay switch controlling extrinsic cell death

scientific article

Modulating cell-to-cell variability and sensitivity to death ligands by co-drugging

scientific article

Molecular Structures and Interactions in the Yeast Kinetochore ⬇️

scientific article published on January 1, 2010

Molecular analysis of kinetochore-microtubule attachment in budding yeast.

scientific article

Mps1 at kinetochores is essential for female mouse meiosis I

scientific journal article

Multiomics Profiling Establishes the Polypharmacology of FDA-Approved CDK4/6 Inhibitors and the Potential for Differential Clinical Activity

scientific article published on 06 June 2019

Multiplexed Exchange-PAINT imaging reveals ligand-dependent EGFR and Met interactions in the plasma membrane

scientific article published on 22 September 2017

Multiplexed Immunofluorescence Reveals Potential PD-1/PD-L1 Pathway Vulnerabilities in Craniopharyngioma.

scientific article published on 2 March 2018

Myeloid antigen-presenting cell niches sustain antitumor T cells and license PD-1 blockade via CD28 costimulation

scientific article published on 04 November 2021

Narrative online guides for the interpretation of digital-pathology images and tissue-atlas data

scientific article published on 08 November 2021

Networks inferred from biochemical data reveal profound differences in toll-like receptor and inflammatory signaling between normal and transformed hepatocytes

scientific article

New approaches to modeling complex biochemistry ⬇️

scientific article published on February 1, 2011

Nociceptor neuroimmune interactomes reveal cell type- and injury-specific inflammatory pain pathways

Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis

scientific article published on 12 April 2009

OpenFold: retraining AlphaFold2 yields new insights into its learning mechanisms and capacity for generalization

scientific article published on 14 May 2024

Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma

scientific article published on 25 January 2021

Phenotypic clustering of yeast mutants based on kinetochore microtubule dynamics

scientific article published on 5 May 2007

Phosphotyrosine signaling proteins that drive oncogenesis tend to be highly interconnected

scientific article

Phylogenetic and structural analysis of centromeric DNA and kinetochore proteins

scientific article

Physicochemical modelling of cell signalling pathways.

scientific article

Predictable Clinical Benefits without Evidence of Synergy in Trials of Combination Therapies with Immune-Checkpoint Inhibitors

scientific article published on 19 January 2022

Probing the Architecture of a Simple Kinetochore Using DNA–Protein Crosslinking ⬇️

scientific article published on December 15, 1997

Profiles of Basal and stimulated receptor signaling networks predict drug response in breast cancer lines

scientific article

Profiling drugs for rheumatoid arthritis that inhibit synovial fibroblast activation ⬇️

scientific article published on 31 October 2016

Profiling phospho-signaling networks in breast cancer using reverse-phase protein arrays ⬇️

scientific article published on September 3, 2012

Programming biological models in Python using PySB

scientific article

Properties of cell death models calibrated and compared using Bayesian approaches

scientific article published on January 2013

Protein structure prediction by AlphaFold2: are attention and symmetries all you need?

Qualifying antibodies for image-based immune profiling and multiplexed tissue imaging

scientific article published on 18 September 2019

Quantification of sensitivity and resistance of breast cancer cell lines to anti-cancer drugs using GR metrics

scientific article

Quantitative analysis of pathways controlling extrinsic apoptosis in single cells

scientific article

Quantitative microscopy of green fluorescent protein-labeled yeast.

scientific article

Rapid phospho-turnover by receptor tyrosine kinases impacts downstream signaling and drug binding

scientific article published on September 2011

Rapid prototyping and clinical testing of a reusable face shield for health care workers responding to the COVID-19 pandemic

scientific article published on 15 April 2020

Real-time imaging of the dynamics of death receptors and therapeutics that overcome TRAIL resistance in tumors ⬇️

scientific article published on July 23, 2012

Receptor-Driven ERK Pulses Reconfigure MAPK Signaling and Enable Persistence of Drug-Adapted BRAF-Mutant Melanoma Cells

scientific article published on 21 October 2020

Receptor-based mechanism of relative sensing and cell memory in mammalian signaling networks

scientific article published on 21 January 2020

Recombination and lineage-specific mutations linked to the emergence of SARS-CoV-2

scientific article published on 06 August 2021

Report on EU-USA workshop: how systems biology can advance cancer research (27 October 2008)

scientific article

Reproducibility will only come with data liberation

scientific article

Response and mechanisms of resistance to larotrectinib and selitrectinib in metastatic undifferentiated sarcoma harboring oncogenic fusion of NTRK1

scientific article published on 14 February 2020

S. cerevisiae chromosomes biorient via gradual resolution of syntely between S phase and anaphase

scientific article published on August 2013

SARS-CoV-2 infection protects against rechallenge in rhesus macaques

scientific article

SYLARAS: A Platform for the Statistical Analysis and Visual Display of Systemic Immunoprofiling Data and Its Application to Glioblastoma

scientific article published on 03 September 2020

Scope2Screen: Focus+Context Techniques for Pathology Tumor Assessment in Multivariate Image Data

scientific article published on 24 December 2021

Selective USP7 inhibition elicits cancer cell killing through a p53-dependent mechanism

scientific article published on 24 March 2020

Sequential application of anticancer drugs enhances cell death by rewiring apoptotic signaling networks.

scientific article

Single cell spatial analysis reveals the topology of immunomodulatory purinergic signaling in glioblastoma

scientific article published in 2022

Single-cell and subcellular pharmacokinetic imaging allows insight into drug action in vivo.

scientific article

Single-cell tumor-immune microenvironment of BRCA1/2 mutated high-grade serous ovarian cancer

scientific article published in 2022

Small-Molecule Screen Identifies De Novo Nucleotide Synthesis as a Vulnerability of Cells Lacking SIRT3.

scientific article published in February 2018

Snapshots of protein dynamics and post-translational modifications in one experiment--beta-catenin and its functions

scientific article published on 4 March 2011

Spindle checkpoint deficiency is tolerated by murine epidermal cells but not hair follicle stem cells

scientific article published on 4 February 2013

Spindle checkpoint proteins and chromosome-microtubule attachment in budding yeast

scientific article

Structure and assembly of turnip crinkle virus. II. Mechanism of reassembly in vitro

scientific article published in October 1986

Structure, Function, and Regulation of Budding Yeast Kinetochores ⬇️

scientific article published on January 1, 2003

Structure-Based Design of a Potent and Selective Covalent Inhibitor for SRC Kinase That Targets a P-Loop Cysteine

scientific article published on 30 January 2020

Structure-guided development of covalent TAK1 inhibitors

scientific article published on 9 December 2016

Studies of TAK1-centered polypharmacology with novel covalent TAK1 inhibitors

scientific article published on 7 December 2016

Surviving apoptosis: life-death signaling in single cells.

scientific article published on 25 April 2015

Synergistic drug-cytokine induction of hepatocellular death as an in vitro approach for the study of inflammation-associated idiosyncratic drug hepatotoxicity.

scientific article

Systematic analysis of BRAF(V600E) melanomas reveals a role for JNK/c-Jun pathway in adaptive resistance to drug-induced apoptosis

scientific article

Systematic calibration of a cell signaling network model

scientific article published on 23 April 2010

Systems biology and combination therapy in the quest for clinical efficacy

scientific article published in September 2006

Targeting immunosuppressive macrophages overcomes PARP inhibitor resistance in BRCA1-associated triple-negative breast cancer

scientific article published on 14 December 2020

The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations

scientific article published on 24 November 2017

The Spatial Landscape of Progression and Immunoediting in Primary Melanoma at Single-Cell Resolution

scientific article published in 2022

The glucose-regulated protein grp94 is related to heat shock protein hsp90.

scientific article published in March 1987

The human kinetochore proteins Nnf1R and Mcm21R are required for accurate chromosome segregation

scientific article

The human kinetochore proteins Nnf1R and Mcm21R are required for accurate chromosome segregation

The logic of EGFR/ErbB signaling: theoretical properties and analysis of high-throughput data

scientific article

The response of human epithelial cells to TNF involves an inducible autocrine cascade

scientific article published on March 2006

The yeast DASH complex forms closed rings on microtubules.

scientific article

Time-resolved phosphoproteomics reveals scaffolding and catalysis-responsive patterns of SHP2-dependent signaling

scientific article published on 23 March 2021

Timing and checkpoints in the regulation of mitotic progression

scientific article

Torin2 Exploits Replication and Checkpoint Vulnerabilities to Cause Death of PI3K-Activated Triple-Negative Breast Cancer Cells

scientific article published on 04 December 2019

Towards a rigorous assessment of systems biology models: the DREAM3 challenges

scientific article

Tracing the pathway of spindle assembly checkpoint signaling

scientific article

Training signaling pathway maps to biochemical data with constrained fuzzy logic: quantitative analysis of liver cell responses to inflammatory stimuli

scientific article

Trimerization of a yeast transcriptional activator via a coiled-coil motif

scientific article published on 01 December 1989

Two genes required for the binding of an essential Saccharomyces cerevisiae kinetochore complex to DNA.

scientific article

Yeast heat shock factor contains separable transient and sustained response transcriptional activators

scientific article published on 01 August 1990

Yeast heat shock factor is an essential DNA-binding protein that exhibits temperature-dependent phosphorylation

scientific article published in September 1988

Yeast kinetochore microtubule dynamics analyzed by high-resolution three-dimensional microscopy

scientific article

p31(comet) acts to ensure timely spindle checkpoint silencing subsequent to kinetochore attachment

scientific article published on 30 September 2011

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