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List of works by Ralf H Adams

A molecular map of murine lymph node blood vascular endothelium at single cell resolution

scientific article published on 30 July 2020

A novel multistep mechanism for initial lymphangiogenesis in mouse embryos based on ultramicroscopy

scientific article

A specialized bone marrow microenvironment for fetal haematopoiesis

scientific article published on 14 March 2022

Activation of endothelial β-catenin signaling induces heart failure.

scientific article

Adaptive immune response in JAM-C-deficient mice: normal initiation but reduced IgG memory

scientific journal article

Age-dependent modulation of vascular niches for haematopoietic stem cells

scientific article published on 13 April 2016

AmotL2 links VE-cadherin to contractile actin fibres necessary for aortic lumen expansion

scientific article published on 7 May 2014

Author Correction: Activation of endothelial β-catenin signaling induces heart failure

scientific article published in Scientific Reports

Blood vessel control of macrophage maturation promotes arteriogenesis in ischemia

scientific article published on 16 October 2017

Blood vessel formation and function in bone

scientific article

Cardiac ischemia activates vascular endothelial cadherin promoter in both preexisting vascular cells and bone marrow cells involved in neovascularization

scientific article published on 16 March 2006

Cdk5 controls lymphatic vessel development and function by phosphorylation of Foxc2.

scientific article

Cell-matrix signals specify bone endothelial cells during developmental osteogenesis.

scientific article published on 20 February 2017

Control of skeletal patterning by ephrinB1-EphB interactions

scientific article published on August 2003

Corrigendum: Age-dependent modulation of vascular niches for haematopoietic stem cells

scientific article published in Nature

Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone

scientific article published on 12 March 2014

DLL1-mediated Notch activation regulates endothelial identity in mouse fetal arteries

scientific journal article

Deficiency of endothelial CXCR4 reduces reendothelialization and enhances neointimal hyperplasia after vascular injury in atherosclerosis-prone mice

scientific article

Developmental timing of CCM2 loss influences cerebral cavernous malformations in mice

scientific article

Direct cell-cell contact with the vascular niche maintains quiescent neural stem cells

scientific article published on 5 October 2014

Distinct fibroblast subsets regulate lacteal integrity through YAP/TAZ-induced VEGF-C in intestinal villi

scientific article published on 14 August 2020

Dll4 and Notch signalling couples sprouting angiogenesis and artery formation

scientific article published on 17 July 2017

Dynamics of endothelial cell behavior in sprouting angiogenesis

scientific article published on October 2010

Endothelial EphB4 maintains vascular integrity and transport function in adult heart

scientific article published on 29 November 2019

Endothelial Jagged1 antagonizes Dll4 regulation of endothelial branching and promotes vascular maturation downstream of Dll4/Notch1.

scientific article

Endothelial Notch activity promotes angiogenesis and osteogenesis in bone

scientific article published on 12 March 2014

Endothelial SRF/MRTF ablation causes vascular disease phenotypes in murine retinae

scientific article published on 8 April 2013

Endothelial Tie1-mediated angiogenesis and vascular abnormalization promote tumor progression and metastasis

scientific article published on 22 January 2018

Endothelial cell-derived non-canonical Wnt ligands control vascular pruning in angiogenesis

scientific article published in April 2014

Endothelial cells are progenitors of cardiac pericytes and vascular smooth muscle cells.

scientific article published on 12 August 2016

Endothelial depletion of murine SRF/MRTF provokes intracerebral hemorrhagic stroke

scientific article

Eph/ephrin molecules--a hub for signaling and endocytosis

scientific article

EphB Signaling Directs Peripheral Nerve Regeneration through Sox2-Dependent Schwann Cell Sorting ⬇️

scientific article published on October 1, 2010

Ephrin-B2 controls PDGFRβ internalization and signaling

scientific article published on December 2013

Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis

scientific article

Ephrin-B2-EphB4 communication mediates tumor-endothelial cell interactions during hematogenous spread to spinal bone in a melanoma metastasis model

scientific article published on 28 September 2020

Erratum: Corrigendum: Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone

scientific article published in Nature

Erratum: Tumour angiogenesis is reduced in the Tc1 mouse model of Down’s syndrome

scientific article published in Nature

Esm1 modulates endothelial tip cell behavior and vascular permeability by enhancing VEGF bioavailability

scientific article published on 23 July 2014

Fbxw7 controls angiogenesis by regulating endothelial Notch activity

scientific article (publication date: 2012)

Flow Dynamics and HSPC Homing in Bone Marrow Microvessels

scientific article published on February 2017

Formation of the Collateral Circulation Is Regulated by Vascular Endothelial Growth Factor-A and A Disintegrin and Metalloprotease Family Members 10 and 17 ⬇️

scientific article published on September 10, 2012

G13 controls angiogenesis through regulation of VEGFR-2 expression

scientific article published on 9 May 2013

Hemogenic endothelium generates mesoangioblasts that contribute to several mesodermal lineages in vivo

scientific article published in May 2014

Identification of a clonally expanding haematopoietic compartment in bone marrow

scientific article published on 27 November 2012

Inducible gene targeting in the neonatal vasculature and analysis of retinal angiogenesis in mice

scientific article published on 12 August 2010

Inhibition of Endothelial NOTCH1 Signaling Attenuates Inflammation by Reducing Cytokine-Mediated Histone Acetylation at Inflammatory Enhancers

scientific article published on 15 February 2018

Inhibition of endothelial Cdk5 reduces tumor growth by promoting non-productive angiogenesis

scientific article published on 8 January 2016

Integrin beta1 subunit controls mural cell adhesion, spreading, and blood vessel wall stability

scientific article

Integrin β1 controls VE-cadherin localization and blood vessel stability

scientific article published on 10 March 2015

Integrin-alpha9 is required for fibronectin matrix assembly during lymphatic valve morphogenesis

scientific article published on August 2009

Integrin-linked kinase controls retinal angiogenesis and is linked to Wnt signaling and exudative vitreoretinopathy

scientific article published on 20 November 2019

Junctional adhesion molecule (JAM)-C deficient C57BL/6 mice develop a severe hydrocephalus

scientific article

KLF4 is a key determinant in the development and progression of cerebral cavernous malformations

scientific article

Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes

scientific article published on 27 June 2019

Loss of vascular endothelial notch signaling promotes spontaneous formation of tertiary lymphoid structures

scientific article published on 19 April 2022

Low wnt/β-catenin signaling determines leaky vessels in the subfornical organ and affects water homeostasis in mice

scientific article published on 01 April 2019

Lymphatic endothelial differentiation: start out with Sox--carry on with Prox

scientific article published on 29 December 2008

MRTF-A controls vessel growth and maturation by increasing the expression of CCN1 and CCN2.

scientific article

Master and commander: continued expression of Prox1 prevents the dedifferentiation of lymphatic endothelial cells

scientific article published in December 2008

Mechanotransduction, PROX1, and FOXC2 cooperate to control connexin37 and calcineurin during lymphatic-valve formation

scientific article published on 2 February 2012

Meningeal lymphatic vessels regulate brain tumor drainage and immunity

scientific article published on 24 February 2020

Mesenchymal stromal cell-derived septoclasts resorb cartilage during developmental ossification and fracture healing

scientific article published on 28 January 2022

NCK-dependent pericyte migration promotes pathological neovascularization in ischemic retinopathy

scientific article published in Nature Communications

Notch controls retinal blood vessel maturation and quiescence

scientific article published on 19 June 2013

PDZ interaction site in ephrinB2 is required for the remodeling of lymphatic vasculature

scientific journal article

Pericytes regulate VEGF-induced endothelial sprouting through VEGFR1.

scientific article published on 17 November 2017

Perilipin+ embryonic preadipocytes actively proliferate along growing vasculatures for adipose expansion

scientific article published on August 2015

Phenotypic analysis of Myo10 knockout (Myo10) mice lacking full-length (motorized) but not brain-specific headless myosin X

scientific article published in Scientific Reports

Plastic roles of pericytes in the blood-retinal barrier.

scientific article

Polarized actin and VE-cadherin dynamics regulate junctional remodelling and cell migration during sprouting angiogenesis

scientific article published on 20 December 2017

Pulmonary pericytes regulate lung morphogenesis.

scientific article published on 22 June 2018

Regulation of monocyte cell fate by blood vessels mediated by Notch signalling.

scientific article published on 31 August 2016

Regulation of tissue morphogenesis by endothelial cell-derived signals

scientific article published on 17 December 2014

Regulation of vascular endothelial growth factor receptor function in angiogenesis by numb and numb-like.

scientific article

Regulation of vascular morphogenesis by Notch signaling

scientific article published on October 2007

RhoA and ROCK mediate histamine-induced vascular leakage and anaphylactic shock.

scientific article

Sample preparation for high-resolution 3D confocal imaging of mouse skeletal tissue

scientific article

Single cell transcriptomics reveals functionally specialized vascular endothelium in brain

scientific article published in 2022

Sox17 promotes tumor angiogenesis and destabilizes tumor vessels in mice

scientific article

Spatial regulation of VEGF receptor endocytosis in angiogenesis

scientific journal article

Spatiotemporal endothelial cell - pericyte association in tumors as shown by high resolution 4D intravital imaging.

scientific article

Spermatid differentiation requires the assembly of a cell polarity complex downstream of junctional adhesion molecule-C

scientific journal article

Stability and function of adult vasculature is sustained by Akt/Jagged1 signalling axis in endothelium

scientific article

Sulindac metabolites decrease cerebrovascular malformations in CCM3-knockout mice

scientific article published on 24 June 2015

Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs

scientific article

Tetraspanin CD9 links junctional adhesion molecule-A to αvβ3 integrin to mediate basic fibroblast growth factor–specific angiogenic signaling ⬇️

scientific article published on February 6, 2013

The Junctional Adhesion Molecule-B regulates JAM-C-dependent melanoma cell metastasis

scientific article

The Sphingosine-1-Phosphate Receptor S1PR1 Restricts Sprouting Angiogenesis by Regulating the Interplay between VE-Cadherin and VEGFR2

The Wnt/beta-catenin pathway modulates vascular remodeling and specification by upregulating Dll4/Notch signaling

scientific journal article

The bone marrow microenvironment at single-cell resolution

scientific article published on 10 April 2019

The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis

scientific article published in June 2009

The sphingosine-1-phosphate receptor S1PR1 restricts sprouting angiogenesis by regulating the interplay between VE-cadherin and VEGFR2.

scientific article published in September 2012

Tie1 deletion inhibits tumor growth and improves angiopoietin antagonist therapy

scientific article published on 16 January 2014

Transcriptional regulation of endothelial cell behavior during sprouting angiogenesis

scientific article published on 28 September 2017

Transit amplifying cells coordinate mouse incisor mesenchymal stem cell activation

scientific article published on 09 August 2019

Tumour angiogenesis is reduced in the Tc1 mouse model of Down's syndrome

scientific article

Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1.

scientific article published on 18 September 2017

Vascular RhoJ is an effective and selective target for tumor angiogenesis and vascular disruption

scientific article published in January 2014

Vascular endothelial adrenomedullin-RAMP2 system is essential for vascular integrity and organ homeostasis

scientific article published on 25 January 2013

Wnt/β-catenin signaling regulates VE-cadherin-mediated anastomosis of brain capillaries by counteracting S1pr1 signaling

scientific article published in Nature Communications

YAP/TAZ direct commitment and maturation of lymph node fibroblastic reticular cells

scientific article published on 24 January 2020

YAP1 and TAZ negatively control bone angiogenesis by limiting hypoxia-inducible factor signaling in endothelial cells

scientific article published on 20 January 2020

cKit Lineage Hemogenic Endothelium-Derived Cells Contribute to Mesenteric Lymphatic Vessels

scientific article published on 10 March 2015

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